Actively targeted in vivo multiplex detection of intrinsic cancer biomarkers using biocompatible SERS nanotags

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Dinish, U S ^a   Balasundaram, Ghayathri ^a   Chang, Young Tae ^a,b   Olivo, Malini ^a,b  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; EPIDERMAL GROWTH FACTOR RECEPTOR; HERMES ANTIGEN; IMMOBILIZED ANTIBODY; NANOPARTICLE; PROTEIN SERINE THREONINE KINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR; TUMOR MARKER;

ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; FEMALE; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE; NEOPLASMS; NUDE MOUSE; RAMAN SPECTROMETRY; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; ANTIBODIES, IMMOBILIZED; ANTIGENS, CD44; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SPECTRUM ANALYSIS, RAMAN; TRANSPLANTATION, HETEROLOGOUS; TUMOR MARKERS, BIOLOGICAL;

EID: 84894191479     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep04075     Document Type: Article

References (53)

1. Kang, H. et al. Near-infrared SERS nanoprobes with plasmonic Au/Ag hollowshell assemblies for in vivo multiplex detection. Adv. Funct. Mater. 23, 3719-3727 (2013).
2. Kho, K. W., Fu, C. Y., Dinish, U. S. & Olivo, M. Clinical SERS: are we there yet? J Biophotonics. 4, 667-684 (2011).
3. Zhang, Y., Hong, H., Myklejord, D. V. & Cai, W. Molecular imaging with SERS-active nanoparticles. Small. 7, 3261-3269 (2011).
4. Xie, W. & Schlucker, S. Medical applications of surface-enhanced Raman scattering. Phys. Chem. Chem. Phys. 15, 5329-5344 (2013).
5. Bantz, K. C. et al. Recent progress in SERS biosensing. Phys. Chem. Chem. Phys. 13, 11551-11567 (2011).
6. Lee, S. et al. Biological imaging of HEK293 cells expressing PLC gamma1 using surface-enhanced Raman microscopy. Anal Chem. 79, 916-922 (2007).
7. Faulds, K., Barbagallo, R. P., Keer, J. T., Smith, W. E. & Graham, D. SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence. Analyst. 129, 567-568 (2004). (Pubitemid 38961982)
8. Woo, M. A. et al. Multiplex immunoassay using fluorescent-surface enhanced Raman spectroscopic dots for the detection of bronchioalveolar stem cells in murine lung. Anal. Chem. 81, 1008-1015 (2009).
9. Zavaleta, C. L. et al. Multiplexed imaging of surface enhanced Raman scattering nanotags in living mice using noninvasive Raman spectroscopy. Proc. Natl. Acad. Sci. U. S. A. 106, 13511-13516 (2009).
10. Maiti, K. K. et al. Multiplex targeted in vivo cancer detection using sensitive nearinfrared SERS nanotags. Nano Today. 7, 85-93 (2012).
11. Dougan, J. A. & Faulds, K. Surface enhanced Raman scattering for multiplexed detection. Analyst. 137, 545-554 (2012).
12. Dinish, U. S., Balasundaram, G., Chang, Y. T. & Olivo, M. Sensitive multiplex detection of serological liver cancer biomarkers using SERS-active photonic crystal fiber probe. J. Biophotonics. 1-10, DOI 10.1002/jbio.201300084 (2013).
13. Keren, S. et al. Noninvasive molecular imaging of small living subjects using Raman spectroscopy. Proc. Natl. Acad. Sci. U. S. A. 105, 5844-5849 (2008). (Pubitemid 351758460)
14. Qian, X. et al. In vivo tumor targeting and spectroscopic detection with surface enhanced Raman nanoparticle tags. Nat. Biotechnol. 26, 83-90 (2008).
15. Maiti, K. K. et al. Development of biocompatible SERS nanotag with increased stability by chemisorption of reporter molecule for in vivo cancer detection. Biosens. Bioelectron. 26, 398-403 (2010).
16. Samanta, A. et al. Ultrasensitive near-infrared Raman reporters for SERS-based in vivo cancer detection. Angew. Chem. Int. Ed. 50, 6089-6092 (2011).
17. Kustner, B. et al. SERS labels for red laser excitation: silica-encapsulated SAMs on tunable gold/silver nanoshells. Angew. Chem. Int. Ed. 48, 1950-1953 (2009).
18. Han, M., Gao, X., Su, J. Z. & Nie, S. Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules. Nat. Biotechnol. 19, 631-635 (2001). (Pubitemid 32625432)
19. Van Sark, M. H. J. G. W. et al. Photooxidation and photobleachingof single CdSe/ZnS qunatum dots probed by room-temperature time-resoled spectroscopy. J. Phys. Chem. B. 105, 8281-8284 (2001).
20. Von Maltzahn, G. et al. SERS-coded gold nanorods as a multifunctional platform for densely multiplexed near-infrared imaging and photothermal heating. Adv. Mater. 21, 3175-3180 (2009).
21. Qian, J., Jiang, L., Cai, F., Wang, D. & He, S. Fluorescence-surface enhanced Raman scattering co-functionalized gold nanorods as near-infrared probes for purely optical in vivo imaging. Biomaterials. 32, 1601-1610 (2011).
22. Wu, L. et al. Simultaneous evaluation of p53 and p21 expression level for early cancer diagnosis using SERS technique. Analyst. 138, 3450-3456 (2013).
23. Sanles-Sobrido, M. et al. Design of SERS-encoded, submicron, hollow particles through confined growth of encapsulated metal nanoparticles. J. Am. Chem. Soc. 131, 2699-2705 (2009).
24. Lee, S. et al. Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres. Biosens. Bioelectron. 24, 2260-2263 (2009).
25. Yuan, H. et al. Quantitative surface-enhanced resonant Raman scattering multiplexing of biocompatible gold nanostars for in vitro and ex vivo detection. Anal. Chem. 85, 208-212 (2013).
26. Xie, J., Zhang, Q., Lee, J. & Wang, D. The synthesis of SERS-active gold nanoflower tags for in vivo applications. ACS Nano. 2, 2473-2480 (2008).
27. Vendrell, M., Maiti, K. K., Dhaliwal, K. & Chang, Y. T. Surface-enhanced Raman scattering in cancer detection and imaging. Trends. Biotechnol. 31, 249-257 (2013).
28. Wang, X. et al. Detection of circulating tumor cells in human peripheral blood using surface-enhanced Raman scattering nanoparticles. Cancer. Res. 71, 526-1532 (2011).
29. Chen, Y. et al. Immunoassay for LMP1 innasopharyngeal tissue basedon surfaceenhanced Raman scattering. Int J Nanomedicine. 7, 73-82 (2012).
30. Wang, H. N. & Vo-Dinh, T. Multiplex detection of breast cancer biomarkers using plasmonic molecular sentinel nanoprobes. Nanotechnology. 20, 065101 (1-6) (2009).
31. Matschulat, A., Drescher, D. & Kneipp, J. Surface-enhanced Raman scattering hybrid nanoprobe multiplexing and imaging in biological systems. ACS Nano. 4, 3259-3269 (2010).
32. Wang, Y., Seebald, J. L., Szeto, D. L. & Irudayaraj, J. Biocompatibility and biodistribution of surface-enhanced Raman scattering nanoprobes in zebrafish embryos: in vivo and multiplex imaging. ACS Nano. 4, 4039-4053 (2010).
33. McVeigh, P. Z., Mallia, R. J., Veilleux, I. & Wilson, B. C. Wide field quantitative multiplex surface enhanced Raman scattering imaging in vivo. J. Biomed. Opt. 18, 046011-1-046011-8 (2013).
34. Zavaleta, C. L. et al. A Raman-based endoscopic strategy for multiplexed molecular imaging. Proc. Natl. Acad. Sci. U. S. A. 110, E2288-2297 (2013).
35. Tsutsui, S. et al. Prognostic and predictive value of epidermal growth factor receptor in recurrent breast cancer. Clin Cancer Res. 8, 3454-3460 (2002). (Pubitemid 35340721)
36. Hiraga, T., Ito, S. & Nakamura, H. Cancer stem-like cell marker cd44 promotes bone metastases by enhancing tumorigenicity, cell motility and hyaluronan production. Cancer Res. 73, 4112-4122 (2013).
37. Bacman, D. et al. TGF-beta receptor 2 down regulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study. BMC Cancer. 7, 156, doi:10.1186/1471-2407-7-156 (2007). (Pubitemid 47487590)
38. Brincker, H. Direct intratumoral chemotherapy. CritRev Oncol Hematol. 15, 91-98 (1993). (Pubitemid 24013563)
39. Walter, K. A., Tamargo, R. J., Olivi, A., Burger, P. C. & Brem, H. Intratumoral chemotherapy. Neurosurgery. 37, 1128-1145 (1995).
40. Voulgaris, S. et al. Intratumoral doxorubicin in patients with malignant brain gliomas. Am J Clin Oncol. 1, 60-64 (2002). (Pubitemid 34131031)
41. Goldberg, E. P., Hadba, A. R., Almond, B. A. & Marotta, J. S. Intratumoral cancer chemotherapy and immunotherapy: opportunities for nonsystemic preoperative drug delivery. J Pharm Pharmacol. 54, 159-180 (2002). (Pubitemid 34150053)
42. Duvillard, C., Romanet, P., Cosmidis, A., Beaudouin, N. & Chauffert, B. Phase 2 study of intratumoral cisplatin and epinephrine treatment for locally recurrent head and neck tumors. Ann Otol Rhinol Laryngol. 113, 229-233 (2004). (Pubitemid 38337770)
43. Lammers, T. et al. Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems. Neoplasia. 8, 788-795 (2006). (Pubitemid 44564834)
44. Yang, L. et al. Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging.. Small. 5, 235-243 (2009).
45. Kong, K. V., Lam, Z., Goh, W. D., Leong, W. K. & Olivo, M. Metal carbonyl-gold nanoparticle conjugates for live-cell SERS imaging. Angew. Chem. Int. Ed. 51, 9796-9799 (2012).
46. Dinish, U. S. et al. Highly sensitive SERS detection of cancer proteins in low sample volume using hollow core photonic crystal fiber. Biosens. Bioelectron. 33, \ 293-298 (2012).
47. Maiti, K. K. et al. Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters. Chem Comm. 47, 3514-3516 (2011).
48. Lampidis, T. J., Hasin, Y., Weiss, M. J. & Chen, L. B. Selective killing of carcinoma cells "in vitro" by lipophilic-cationic compounds: a cellular basis. Biomed Pharmacother. 39, 220-226 (1985). (Pubitemid 16194118)
49. Sonavane, G., Tomoda, K. & Makino, K. Biodistribution of colloidal gold nanoparticles after intravenous administration: effect of particle size. Colloids Surf B Biointerfaces. 66, 274-280 (2008).
50. Xie, H., Goins, B., Bao, A., Wang, Z. J. & Phillips, W. T. Effect of intratumoral administration on biodistribution of 64Cu-labeled nanoshells. Int. J Nanomedicine. 7, 2227-2238 (2012).
51. Yong, K. T., Roy, I., Ding, H., Bergey, E. J. & Prasad, P. N. Biocompatible nearinfrared quantum dots as ultrasensitive probes for long-term in vivo imaging applications. Small. 5, 1997-2004 (2009).
52. Hong, W. S. & Hong, S. I. Clinical usefulness of alpha-1-antitrypsin in the diagnosis of hepatocellular carcinoma. J. Korean Med Sci. 6, 206-213 (1991).
53. Waldmann, T. A. & McIntire, K. R. The use of a radioimmunoassay for alphafetoprotein in the diagnosis of malignancy. Cancer. 34, 1510-1515 (1974).