Unsupervised unmixing of Raman microspectroscopic images for morphochemical analysis of non-dried brain tumor specimens

Analytical and Bioanalytical Chemistry

Volumn 403, Issue 3, 2012, Pages 719-725

  Bergner, Norbert ^a   Krafft, Christoph ^a   Geiger, Kathrin D ^b   Kirsch, Matthias ^b   Schackert, Gabriele ^b   Popp, Jürgen ^a,c  

^a LEIBNIZ INSTITUTE OF PHOTONIC TECHNOLOGY   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Brain tumors; Hyperspectral unmixing; Non dried specimens; Raman imaging

Indexed keywords

AQUEOUS BUFFER; ASTROCYTOMA; BRAIN TUMORS; CELL NUCLEUS; CHOLESTEROL ESTERS; CLINICAL TOOLS; DATA SETS; DRYING EFFECTS; ENDMEMBERS; EPENDYMOMA; GLIOBLASTOMA MULTIFORME; GRANULAR LAYER; HYPERSPECTRAL UNMIXING; LABEL FREE; MICROSPECTROSCOPIC IMAGING; MOLECULAR CONTRAST; NON-DRIED SPECIMENS; RAMAN IMAGING; RAMAN SPECTROSCOPIC; REFERENCE MATERIAL; SINGLE-MODE LASERS; SPATIAL RESOLUTION; SPECTRAL DECOMPOSITION TECHNIQUE; SPECTRAL SIGNATURE; STEP SIZE; SUB-CELLULAR; TISSUE SECTIONS; TUMOR CELLS; UNMIXING; UNSUPERVISED APPROACHES;

ALGORITHMS; CHOLESTEROL; DIAGNOSIS; ESTERIFICATION; ESTERS; LIPIDS; NUCLEIC ACIDS; RAMAN SPECTROSCOPY; TUMORS;

BRAIN;

ALGORITHM; ASTROCYTOMA; BRAIN; BRAIN TUMOR; CONFERENCE PAPER; EPENDYMOMA; GLIOBLASTOMA; HUMAN; LABORATORY DIAGNOSIS; METHODOLOGY; PATHOLOGY; RAMAN SPECTROMETRY;

ALGORITHMS; ASTROCYTOMA; BRAIN; BRAIN NEOPLASMS; EPENDYMOMA; GLIOBLASTOMA; HUMANS; SPECIMEN HANDLING; SPECTRUM ANALYSIS, RAMAN;

EID: 84861229379     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-012-5858-1     Document Type: Conference Paper

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