Computational de novo design of a four-helix bundle protein - DND-4HB

Protein Science

Volumn 24, Issue 4, 2015, Pages 434-445

  Murphy, Grant S ^a   Sathyamoorthy, Bharatwaj ^b,f   Der, Bryan S ^c   Machius, Mischa C ^d   Pulavarti, Surya V ^b,e   Szyperski, Thomas ^b,e   Kuhlman, Brian ^c,d  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e Northeast Structural Genomics Consortium   (United States)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

computational protein design; de novo protein design; four helix bundle; NMR structure; rosetta

Indexed keywords

DND 4HB PROTEIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CIRCULAR DICHROISM; CONCENTRATION (PARAMETERS); HYDRODYNAMICS; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTEIN TARGETING; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MOLECULAR MODEL; PROCEDURES; PROTEIN ENGINEERING;

AMINO ACID SEQUENCE; CLONING, MOLECULAR; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN FOLDING; RECOMBINANT PROTEINS;

EID: 84938211722     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2577     Document Type: Article

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