An interferon-γ-delivery system based on chitosan/poly(γ-glutamic acid) polyelectrolyte complexes modulates macrophage-derived stimulation of cancer cell invasion in vitro

Acta Biomaterialia

Volumn 23, Issue , 2015, Pages 157-171

  Cardoso, Ana P ^a,b,c   Gonçalves, Raquel M ^a,b   Antunes, Joana C ^a,b,c   Pinto, Marta L ^a,b,c   Pinto, Ana T ^a,b,c   Castro, Flávia ^a,b,c   Monteiro, Cátia ^a,b   Barbosa, Mário A ^a,b,c   Oliveira, Maria José ^a,b,d  

^a UNIVERSITY OF PORTO   (Portugal)

^b INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

^d University of Porto   (Portugal)

Author keywords

Cancer; Drug delivery; Immunomodulation; Macrophage; Polyelectrolyte multilayers

Indexed keywords

AMINO ACIDS; BIOCOMPATIBILITY; CHITOSAN; CONTROLLED DRUG DELIVERY; CYTOLOGY; GLYCOPROTEINS; HYALURONIC ACID; MACROPHAGES; MULTILAYER FILMS; MULTILAYERS; POLYELECTROLYTES; TARGETED DRUG DELIVERY; TUMORS;

CANCER CELLS; CELL INVASION; DELIVERY SYSTEMS; GASTRIC CANCER CELLS; GLUTAMIC ACID; IMMUNO MODULATIONS; IN-VITRO; POLYELECTROLYTE COMPLEXES; POLYELECTROLYTE MULTILAYER; POLYELECTROLYTE MULTILAYER FILM;

DISEASES;

CHITOSAN; CYTOKINE; DRUG CARRIER; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 6; POLY(GAMMA GLUTAMIC ACID); POLYAMINOACID; POLYELECTROLYTE; RECOMBINANT GAMMA INTERFERON; UNCLASSIFIED DRUG; ELECTROLYTE; POLY(GAMMA-GLUTAMIC ACID); POLYGLUTAMIC ACID;

AGS CELL LINE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; CANCER CELL; CELL INVASION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSKELETON; DRUG DELIVERY SYSTEM; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; HYDROPHILICITY; IMMUNOMODULATION; IN VITRO STUDY; MACROPHAGE FUNCTION; PARTICLE SIZE; PHENOTYPE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STATIC ELECTRICITY; SURFACE CHARGE; SUSTAINED DRUG RELEASE; ANALOGS AND DERIVATIVES; CELL CULTURE; CELL LINE; CHEMISTRY; DRUG EFFECTS; IMMUNOLOGY; MACROPHAGE; NEOPLASMS, EXPERIMENTAL; PATHOLOGY; TUMOR INVASION;

CELL LINE; CELLS, CULTURED; CHITOSAN; CYTOKINES; ELECTROLYTES; HUMANS; INTERFERON-GAMMA; MACROPHAGES; NEOPLASM INVASIVENESS; NEOPLASMS, EXPERIMENTAL; POLYGLUTAMIC ACID;

EID: 84938199069     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2015.05.022     Document Type: Article

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