Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y 1086, c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity

Oncogene

Volumn 33, Issue 16, 2014, Pages 2123-2133

  Cardoso, A P ^a   Pinto, M L ^a   Pinto, A T ^a   Oliveira, M I ^a   Pinto, M T ^a   Goncalves R ^a   Relvas, J B ^b,c   Figueiredo, C ^a,c   Seruca, R ^a,c   Mantovani, A ^d,e   Mareel, M ^f   Barbosa, M A ^a   Oliveira, M J ^a,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c University of Porto   (Portugal)

^d HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

^f GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

cancer cell invasion; colon cancer; gastric cancer; invasion related signaling pathways; macrophages; tumor microenvironment

Indexed keywords

BLOTTING, WESTERN; CACO-2 CELLS; CELL LINE, TUMOR; CELL MOVEMENT; CELLS, CULTURED; COCULTURE TECHNIQUES; COLORECTAL NEOPLASMS; HUMANS; MACROPHAGES; MATRIX METALLOPROTEINASES; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOPLASM INVASIVENESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECEPTOR, EPIDERMAL GROWTH FACTOR; RHO GTP-BINDING PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TIME-LAPSE IMAGING; TYROSINE;

EID: 84899425243     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.154     Document Type: Article

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