Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour

International Journal of Neuropsychopharmacology

Volumn 29, Issue 4, 2014, Pages

  Gibney, Sinead M ^a   Fagan, Eimear M ^a   Waldron, Ann Marie ^a   O'Byrne, Jordan ^a   Connor, Thomas J ^a   Harkin, Andrew ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Allopurinol; forced swimming test; kynurenine pathway; stress; tryptophan 2,3 dioxygenase

Indexed keywords

ALLOPURINOL; CORTICOSTERONE; GLUCOCORTICOID; KYNURENINE; TRYPTOPHAN 2,3 DIOXYGENASE;

ACUTE STRESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; BRAIN CORTEX; CHRONIC STRESS; CONTROLLED STUDY; DEPRESSION; ENZYME ACTIVITY; ENZYME INHIBITION; FORCED SWIM TEST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMOBILITY; IMMOBILIZATION STRESS; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRYPTOPHAN METABOLISM; WEIGHT GAIN;

EID: 84938082923     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145713001673     Document Type: Article

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