Psychological stress-induced, IDO1-dependent tryptophan catabolism: Implications on immunosuppression in mice and humans

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Kiank, Cornelia ^a   Zeden, Jan Philip ^a   Drude, Solveig ^a   Domanska, Grazyna ^a   Fusch, Gerhard ^a   Otten, Winfried ^b   Schuett, Christine ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLTRYPTOPHAN; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; KYNURENIC ACID; KYNURENINE; MESSENGER RNA; MIFEPRISTONE; QUINOLINIC ACID; SEROTONIN; TRYPTOPHAN; TRYPTOPHAN DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 1-METHYLTRYPTOPHAN; DRUG DERIVATIVE;

ABDOMINAL SURGERY; ACOUSTIC STRESS; ACUTE STRESS; ADULT; AGED; AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEREMIA; BAGG ALBINO MOUSE; BLOOD LEVEL; BRAIN; CATABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; EXPLORATORY BEHAVIOR; FEMALE; GENE EXPRESSION; HOST RESISTANCE; HUMAN; IMMOBILIZATION STRESS; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LUNG; LYMPHOCYTOPENIA; MALE; MENTAL STRESS; METABOLITE; MOUSE; NONHUMAN; PEYER PATCH; PILOT STUDY; POSTOPERATIVE PERIOD; SEROTONIN BLOOD LEVEL; SPLEEN; SPLEEN CELL; SURGICAL PATIENT; THYMUS ATROPHY; UPREGULATION; WEIGHT REDUCTION; ANIMAL; BLOOD; DRUG ANTAGONISM; GENETICS; IMMUNOSUPPRESSIVE TREATMENT; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; FEMALE; HUMANS; IMMUNOSUPPRESSION; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTERFERON-GAMMA; KYNURENIC ACID; MALE; MICE; MICE, INBRED BALB C; MIDDLE AGED; MIFEPRISTONE; SEROTONIN; STRESS, PSYCHOLOGICAL; TRYPTOPHAN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77955648350     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011825     Document Type: Article

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