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Volumn 523, Issue 7559, 2015, Pages 226-230

Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; CRE RECOMBINASE; MYOSIN HEAVY CHAIN ALPHA; HIF1A PROTEIN, MOUSE; HYBRID PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; RECOMBINASE;

EID: 84938069663     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14582     Document Type: Article
Times cited : (254)

References (29)
  • 1
    • 64249107059 scopus 로고    scopus 로고
    • Evidence for cardiomyocyte renewal in humans
    • Bergmann, O. et al. Evidence for cardiomyocyte renewal in humans. Science 324, 98-102 (2009).
    • (2009) Science , vol.324 , pp. 98-102
    • Bergmann, O.1
  • 2
    • 84873305461 scopus 로고    scopus 로고
    • Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart
    • Malliaras, K. et al. Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart. EMBO Mol. Med. 5, 191-209 (2013).
    • (2013) EMBO Mol. Med. , vol.5 , pp. 191-209
    • Malliaras, K.1
  • 3
    • 84872611623 scopus 로고    scopus 로고
    • Mammalian heart renewal by pre-existing cardiomyocytes
    • Senyo, S. E. et al. Mammalian heart renewal by pre-existing cardiomyocytes. Nature 493, 433-436 (2013).
    • (2013) Nature , vol.493 , pp. 433-436
    • Senyo, S.E.1
  • 4
    • 67650569135 scopus 로고    scopus 로고
    • Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
    • Bersell, K., Arab, S., Haring, B. & Kuhn, B. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell 138, 257-270 (2009).
    • (2009) Cell , vol.138 , pp. 257-270
    • Bersell, K.1    Arab, S.2    Haring, B.3    Kuhn, B.4
  • 5
    • 84902602979 scopus 로고    scopus 로고
    • Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice
    • Ali, S. R. et al. Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. Proc. Natl Acad. Sci. USA 111, 8850-8855 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 8850-8855
    • Ali, S.R.1
  • 7
    • 77957584397 scopus 로고    scopus 로고
    • O2 regulates stem cells through Wnt/b-catenin signalling
    • Mazumdar, J. et al. O2 regulates stem cells through Wnt/b-catenin signalling. Nature Cell Biol. 12, 1007-1013 (2010).
    • (2010) Nature Cell Biol. , vol.12 , pp. 1007-1013
    • Mazumdar, J.1
  • 8
    • 77956217067 scopus 로고    scopus 로고
    • Regulation of the HIF-1a level is essential for hematopoietic stem cells
    • Takubo, K. et al. Regulation of the HIF-1a level is essential for hematopoietic stem cells. Cell Stem Cell 7, 391-402 (2010).
    • (2010) Cell Stem Cell , vol.7 , pp. 391-402
    • Takubo, K.1
  • 9
    • 84872132572 scopus 로고    scopus 로고
    • Aspecializedmicrovascular domainin the mouse neural stem cell niche
    • Culver, J.C.,Vadakkan, T. J.&Dickinson,M. E.Aspecializedmicrovascular domainin the mouse neural stem cell niche. PLoS ONE 8, e53546 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e53546
    • Culver, J.C.1    Vadakkan, T.J.2    Dickinson, M.E.3
  • 10
    • 34248359065 scopus 로고    scopus 로고
    • Distribution of hematopoietic stemcells in the bone marrow according to regional hypoxia
    • Parmar, K., Mauch, P., Vergilio, J. A., Sackstein, R. & Down, J. D. Distribution of hematopoietic stemcells in the bone marrow according to regional hypoxia. Proc. Natl Acad. Sci. USA 104, 5431-5436 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 5431-5436
    • Parmar, K.1    Mauch, P.2    Vergilio, J.A.3    Sackstein, R.4    Down, J.D.5
  • 11
    • 84899533827 scopus 로고    scopus 로고
    • The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response
    • Puente, B. N. et al. The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell 157, 565-579 (2014).
    • (2014) Cell , vol.157 , pp. 565-579
    • Puente, B.N.1
  • 12
    • 77954345078 scopus 로고    scopus 로고
    • Oxygen homeostasis interdiscip
    • Semenza, G. L. Oxygen homeostasis. Wiley Interdiscip. Rev. Syst. Biol. Med. 2, 336-361 (2010).
    • (2010) Rev. Syst. Biol. Med. , vol.2 , pp. 336-361
    • Semenza, G.L.1
  • 13
    • 23744451791 scopus 로고    scopus 로고
    • A hypoxia-inducible vigilant vector system for activating therapeutic genes in ischemia
    • Tang, Y. L. et al. A hypoxia-inducible vigilant vector system for activating therapeutic genes in ischemia. Gene Ther. 12, 1163-1170 (2005).
    • (2005) Gene Ther. , vol.12 , pp. 1163-1170
    • Tang, Y.L.1
  • 14
    • 0035917313 scopus 로고    scopus 로고
    • HIFa targetedfor VHL-mediated destructionby proline hydroxylation: Implications for O2 sensing
    • Ivan,M. et al. HIFa targetedfor VHL-mediated destructionby proline hydroxylation: Implications for O2 sensing. Science 292, 464-468 (2001).
    • (2001) Science , vol.292 , pp. 464-468
    • Ivan, M.1
  • 15
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-A to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola, P. et al. Targeting of HIF-a to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292, 468-472 (2001).
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1
  • 16
    • 79953294165 scopus 로고    scopus 로고
    • Cellular hypoxia of pancreatic b-cells due to high levels of oxygen consumption for insulin secretion in vitro
    • Sato, Y. et al. Cellular hypoxia of pancreatic b-cells due to high levels of oxygen consumption for insulin secretion in vitro. J. Biol. Chem. 286, 12524-12532 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 12524-12532
    • Sato, Y.1
  • 17
    • 84892913238 scopus 로고    scopus 로고
    • C-Kit-positive cardiac stem cells nested in hypoxic niches are activated by stem cell factor reversing the aging myopathy
    • Sanada, F. et al. c-Kit-positive cardiac stem cells nested in hypoxic niches are activated by stem cell factor reversing the aging myopathy. Circ. Res. 114, 41-55 (2014).
    • (2014) Circ. Res. , vol.114 , pp. 41-55
    • Sanada, F.1
  • 18
    • 84900560043 scopus 로고    scopus 로고
    • C-kit1 cells minimally contribute cardiomyocytes to the heart
    • Van Berlo, J. H. et al. c-kit1 cells minimally contribute cardiomyocytes to the heart. Nature 509, 337-341 (2014).
    • (2014) Nature , vol.509 , pp. 337-341
    • Van Berlo, J.H.1
  • 19
    • 84888135216 scopus 로고    scopus 로고
    • Sca1-derived cells are a source of myocardial renewal in the murine adult heart
    • Uchida, S. et al. Sca1-derived cells are a source of myocardial renewal in the murine adult heart. Stem Cell Rep. 1, 397-410 (2013).
    • (2013) Stem Cell Rep. , vol.1 , pp. 397-410
    • Uchida, S.1
  • 20
    • 79953891392 scopus 로고    scopus 로고
    • Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors
    • Tian, Y.M. et al.Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors. J. Biol. Chem. 286, 13041-13051 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 13041-13051
    • Tian, Y.M.1
  • 21
    • 33750734736 scopus 로고    scopus 로고
    • Cardiomyocyte DNA synthesis and binucleation during murine development
    • Soonpaa, M. H., Kim, K. K., Pajak, L., Franklin, M. & Field, L. J. Cardiomyocyte DNA synthesis and binucleation during murine development. Am. J. Physiol. 271, H2183-H2189 (1996).
    • (1996) Am. J. Physiol. , vol.271 , pp. 2183-2189
    • Soonpaa, M.H.1    Kim, K.K.2    Pajak, L.3    Franklin, M.4    Field, L.J.5
  • 22
    • 84896929687 scopus 로고    scopus 로고
    • Metabolic requirements for the maintenance of selfrenewing stem cells
    • Ito, K. & Suda, T. Metabolic requirements for the maintenance of selfrenewing stem cells. Nature Rev. Mol. Cell Biol. 15, 243-256 (2014).
    • (2014) Nature Rev. Mol. Cell Biol. , vol.15 , pp. 243-256
    • Ito, K.1    Suda, T.2
  • 23
    • 84884565811 scopus 로고    scopus 로고
    • Hypoxia and metabolic properties of hematopoietic stem cells
    • Zhang, C. C. & Sadek, H. A. Hypoxia and metabolic properties of hematopoietic stem cells. Antioxid. Redox Signal. 20, 1891-1901 (2014).
    • (2014) Antioxid. Redox Signal. , vol.20 , pp. 1891-1901
    • Zhang, C.C.1    Sadek, H.A.2
  • 25
    • 30444445382 scopus 로고    scopus 로고
    • Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
    • Safran, M. et al. Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production. Proc. Natl Acad. Sci. USA 103, 105-110 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 105-110
    • Safran, M.1
  • 26
    • 77749323185 scopus 로고    scopus 로고
    • RNA-seq analysis to capture the transcriptome landscape of a single cell
    • Tang, F. et al. RNA-seq analysis to capture the transcriptome landscape of a single cell. Nature Protocols 5, 516-535 (2010).
    • (2010) Nature Protocols , vol.5 , pp. 516-535
    • Tang, F.1
  • 27
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-seq
    • Trapnell, C., Pachter, L.&Salzberg, S. L. TopHat: Discovering splice junctions with RNA-seq. Bioinformatics 25, 1105-1111 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 28
    • 75249087100 scopus 로고    scopus 로고
    • EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson, M. D., McCarthy, D. J. & Smyth, G. K. edgeR: A Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139-140 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 29
    • 42649094152 scopus 로고    scopus 로고
    • Myocardial capillary supply is limited in hypertrophic cardiomyopathy: A morphological analysis
    • Johansson, B., Morner, S., Waldenstrom, A. & Stal, P. Myocardial capillary supply is limited in hypertrophic cardiomyopathy: A morphological analysis. Int. J. Cardiol. 126, 252-257 (2008). 7
    • (2008) Int. J. Cardiol. , vol.126 , pp. 252-257
    • Johansson, B.1    Morner, S.2    Waldenstrom, A.3    Stal, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.