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Volumn 93, Issue 8, 2015, Pages 867-878

The chemical inhibitors of cellular death, PJ34 and Necrostatin-1, down-regulate IL-33 expression in liver

Author keywords

Acute hepatitis; Cytokine; Fibroblasts; IL 33; PARP 1; RIP kinase

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CONCANAVALIN A; INTERLEUKIN 33; LIVER PROTECTIVE AGENT; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NECROSTATIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLYINOSINIC POLYCYTIDYLIC ACID; STAUROSPORINE; UNCLASSIFIED DRUG; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; N-(OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)-N,N-DIMETHYLACETAMIDE HYDROCHLORIDE; NECROSTATIN-1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PHENANTHRENE DERIVATIVE;

EID: 84937967401     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-015-1270-6     Document Type: Article
Times cited : (29)

References (61)
  • 1
    • 77955591462 scopus 로고    scopus 로고
    • Hepatocyte death: a clear and present danger
    • COI: 1:CAS:528:DC%2BC3cXhtVyku7rK, PID: 20664081
    • Malhi H, Guicciardi ME, Gores GJ (2010) Hepatocyte death: a clear and present danger. Physiol Rev 90:1165–1194
    • (2010) Physiol Rev , vol.90 , pp. 1165-1194
    • Malhi, H.1    Guicciardi, M.E.2    Gores, G.J.3
  • 2
    • 77957105977 scopus 로고    scopus 로고
    • Molecular mechanisms of necroptosis: an ordered cellular explosion
    • COI: 1:CAS:528:DC%2BC3cXhtFajsL7P, PID: 20823910
    • Vandenabeele P, Galluzzi L, Vanden Berghe T, Kroemer G (2010) Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 11:700–714
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 700-714
    • Vandenabeele, P.1    Galluzzi, L.2    Vanden Berghe, T.3    Kroemer, G.4
  • 3
    • 66449133280 scopus 로고    scopus 로고
    • Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
    • COI: 1:CAS:528:DC%2BD1MXps1eiu7o%3D, PID: 19524513
    • Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M et al (2009) Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137:1112–1123
    • (2009) Cell , vol.137 , pp. 1112-1123
    • Cho, Y.S.1    Challa, S.2    Moquin, D.3    Genga, R.4    Ray, T.D.5    Guildford, M.6
  • 4
    • 66749183275 scopus 로고    scopus 로고
    • Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
    • COI: 1:CAS:528:DC%2BD1MXps1eiu70%3D, PID: 19524512
    • He S, Wang L, Miao L, Wang T, Du F, Zhao L et al (2009) Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 137:1100–1111
    • (2009) Cell , vol.137 , pp. 1100-1111
    • He, S.1    Wang, L.2    Miao, L.3    Wang, T.4    Du, F.5    Zhao, L.6
  • 5
    • 67650812332 scopus 로고    scopus 로고
    • RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
    • COI: 1:CAS:528:DC%2BD1MXos1Sqt7Y%3D
    • Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC et al (2009) RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science (New York, NY) 325:332–336
    • (2009) Science (New York, NY) , vol.325 , pp. 332-336
    • Zhang, D.W.1    Shao, J.2    Lin, J.3    Zhang, N.4    Lu, B.J.5    Lin, S.C.6
  • 6
    • 79957483071 scopus 로고    scopus 로고
    • TNF-alpha induced apoptosis is accompanied with rapid CD30 and slower CD45 shedding from K-562 cells
    • COI: 1:CAS:528:DC%2BC3MXhs1Gitrg%3D, PID: 21221555
    • Jurisic V, Srdic-Rajic T, Konjevic G, Bogdanovic G, Colic M (2011) TNF-alpha induced apoptosis is accompanied with rapid CD30 and slower CD45 shedding from K-562 cells. The Journal of membrane biology 239:115–122
    • (2011) The Journal of membrane biology , vol.239 , pp. 115-122
    • Jurisic, V.1    Srdic-Rajic, T.2    Konjevic, G.3    Bogdanovic, G.4    Colic, M.5
  • 8
    • 79957438570 scopus 로고    scopus 로고
    • Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice
    • COI: 1:CAS:528:DC%2BC3MXmsFCqt70%3D, PID: 21425308
    • Csak T, Dolganiuc A, Kodys K, Nath B, Petrasek J, Bala S et al (2011) Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice. Hepatology 53:1917–1931
    • (2011) Hepatology , vol.53 , pp. 1917-1931
    • Csak, T.1    Dolganiuc, A.2    Kodys, K.3    Nath, B.4    Petrasek, J.5    Bala, S.6
  • 9
    • 0026643743 scopus 로고
    • A T cell-dependent experimental liver injury in mice inducible by concanavalin A
    • COI: 1:CAS:528:DyaK38XltVGqtrw%3D, PID: 1634608
    • Tiegs G, Hentschel J, Wendel A (1992) A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J Clin Invest 90:196–203
    • (1992) J Clin Invest , vol.90 , pp. 196-203
    • Tiegs, G.1    Hentschel, J.2    Wendel, A.3
  • 10
    • 0034624976 scopus 로고    scopus 로고
    • Critical contribution of liver natural killer T cells to a murine model of hepatitis
    • COI: 1:CAS:528:DC%2BD3cXjsVWms78%3D, PID: 10792025
    • Takeda K, Hayakawa Y, Van Kaer L, Matsuda H, Yagita H, Okumura K (2000) Critical contribution of liver natural killer T cells to a murine model of hepatitis. Proc Natl Acad Sci U S A 97:5498–5503
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 5498-5503
    • Takeda, K.1    Hayakawa, Y.2    Van Kaer, L.3    Matsuda, H.4    Yagita, H.5    Okumura, K.6
  • 11
    • 1542466794 scopus 로고    scopus 로고
    • Critical roles of TRAIL in hepatic cell death and hepatic inflammation
    • COI: 1:CAS:528:DC%2BD2cXjsVGmuw%3D%3D, PID: 14702109
    • Zheng SJ, Wang P, Tsabary G, Chen YH (2004) Critical roles of TRAIL in hepatic cell death and hepatic inflammation. J Clin Invest 113:58–64
    • (2004) J Clin Invest , vol.113 , pp. 58-64
    • Zheng, S.J.1    Wang, P.2    Tsabary, G.3    Chen, Y.H.4
  • 12
    • 49449097533 scopus 로고    scopus 로고
    • Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease
    • COI: 1:CAS:528:DC%2BD1cXpvFOisrg%3D, PID: 18667695
    • Takeda K, Kojima Y, Ikejima K, Harada K, Yamashina S, Okumura K et al (2008) Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease. Proc Natl Acad Sci U S A 105:10895–10900
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 10895-10900
    • Takeda, K.1    Kojima, Y.2    Ikejima, K.3    Harada, K.4    Yamashina, S.5    Okumura, K.6
  • 13
    • 68149171396 scopus 로고    scopus 로고
    • Hepatocyte-specific NEMO deletion promotes NK/NKT cell- and TRAIL-dependent liver damage
    • COI: 1:CAS:528:DC%2BD1MXps1enu70%3D, PID: 19635861
    • Beraza N, Malato Y, Sander LE, Al-Masaoudi M, Freimuth J, Riethmacher D et al (2009) Hepatocyte-specific NEMO deletion promotes NK/NKT cell- and TRAIL-dependent liver damage. J Exp Med 206:1727–1737
    • (2009) J Exp Med , vol.206 , pp. 1727-1737
    • Beraza, N.1    Malato, Y.2    Sander, L.E.3    Al-Masaoudi, M.4    Freimuth, J.5    Riethmacher, D.6
  • 14
    • 53149111140 scopus 로고    scopus 로고
    • Differential roles of JNK in ConA/GalN and ConA-induced liver injury in mice
    • COI: 1:CAS:528:DC%2BD1cXht1Cjt7nJ, PID: 18772342
    • Ni HM, Chen X, Ding WX, Schuchmann M, Yin XM (2008) Differential roles of JNK in ConA/GalN and ConA-induced liver injury in mice. Am J Pathol 173:962–972
    • (2008) Am J Pathol , vol.173 , pp. 962-972
    • Ni, H.M.1    Chen, X.2    Ding, W.X.3    Schuchmann, M.4    Yin, X.M.5
  • 15
    • 0032737476 scopus 로고    scopus 로고
    • Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation
    • COI: 1:CAS:528:DyaK1MXnsFSlsbs%3D, PID: 10534346
    • Kunstle G, Hentze H, Germann PG, Tiegs G, Meergans T, Wendel A (1999) Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation. Hepatology 30:1241–1251
    • (1999) Hepatology , vol.30 , pp. 1241-1251
    • Kunstle, G.1    Hentze, H.2    Germann, P.G.3    Tiegs, G.4    Meergans, T.5    Wendel, A.6
  • 16
    • 81855183262 scopus 로고    scopus 로고
    • Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury
    • COI: 1:CAS:528:DC%2BC3MXhsFSjt7rM, PID: 21878202
    • Liedtke C, Bangen JM, Freimuth J, Beraza N, Lambertz D, Cubero FJ et al (2011) Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury. Gastroenterology 141:2176–2187
    • (2011) Gastroenterology , vol.141 , pp. 2176-2187
    • Liedtke, C.1    Bangen, J.M.2    Freimuth, J.3    Beraza, N.4    Lambertz, D.5    Cubero, F.J.6
  • 17
    • 84886563312 scopus 로고    scopus 로고
    • Protective effects of necrostatin-1 against concanavalin A-induced acute hepatic injury in mice
    • Zhou Y, Dai W, Lin C, Wang F, He L, Shen M et al (2013) Protective effects of necrostatin-1 against concanavalin A-induced acute hepatic injury in mice. Mediat Inflamm 2013:706156
    • (2013) Mediat Inflamm , vol.2013 , pp. 706156
    • Zhou, Y.1    Dai, W.2    Lin, C.3    Wang, F.4    He, L.5    Shen, M.6
  • 19
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • COI: 1:CAS:528:DC%2BD3MXnvFegsL0%3D, PID: 11607032
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA (2001) Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413:732–738
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 20
    • 56549116047 scopus 로고    scopus 로고
    • Toll-like receptor and RIG-I-like receptor signaling
    • COI: 1:CAS:528:DC%2BD1MXpvFKrsQ%3D%3D, PID: 19076341
    • Kawai T, Akira S (2008) Toll-like receptor and RIG-I-like receptor signaling. Ann N Y Acad Sci 1143:1–20
    • (2008) Ann N Y Acad Sci , vol.1143
    • Kawai, T.1    Akira, S.2
  • 21
    • 0037256608 scopus 로고    scopus 로고
    • Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model
    • COI: 1:CAS:528:DC%2BD3sXjtlOgtbw%3D, PID: 12708612
    • Weber LW, Boll M, Stampfl A (2003) Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. Crit Rev Toxicol 33:105–136
    • (2003) Crit Rev Toxicol , vol.33 , pp. 105-136
    • Weber, L.W.1    Boll, M.2    Stampfl, A.3
  • 22
    • 77955142252 scopus 로고    scopus 로고
    • Interleukin-33 overexpression is associated with liver fibrosis in mice and humans
    • COI: 1:CAS:528:DC%2BC3cXhsFyrtLvO, PID: 19508382
    • Marvie P, Lisbonne M, L’Helgoualc’h A, Rauch M, Turlin B, Preisser L et al (2010) Interleukin-33 overexpression is associated with liver fibrosis in mice and humans. J Cell Mol Med 14:1726–1739
    • (2010) J Cell Mol Med , vol.14 , pp. 1726-1739
    • Marvie, P.1    Lisbonne, M.2    L’Helgoualc’h, A.3    Rauch, M.4    Turlin, B.5    Preisser, L.6
  • 23
    • 84865169674 scopus 로고    scopus 로고
    • IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology
    • COI: 1:CAS:528:DC%2BC38XhsFSis7rE, PID: 22530772
    • Arshad MI, Piquet-Pellorce C, Samson M (2012) IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology. Liver Int 32:1200–1210
    • (2012) Liver Int , vol.32 , pp. 1200-1210
    • Arshad, M.I.1    Piquet-Pellorce, C.2    Samson, M.3
  • 24
    • 79960721309 scopus 로고    scopus 로고
    • NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis
    • COI: 1:CAS:528:DC%2BC3MXpt1yhsbk%3D, PID: 21557213
    • Arshad MI, Rauch M, L’Helgoualc’h A, Julia V, Leite-de-Moraes MC, Lucas-Clerc C et al (2011) NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis. Eur J Immunol 41:2341–2348
    • (2011) Eur J Immunol , vol.41 , pp. 2341-2348
    • Arshad, M.I.1    Rauch, M.2    L’Helgoualc’h, A.3    Julia, V.4    Leite-de-Moraes, M.C.5    Lucas-Clerc, C.6
  • 25
    • 84884168728 scopus 로고    scopus 로고
    • Pathogenic mouse hepatitis virus or poly(I:C) induce IL-33 in hepatocytes in murine models of hepatitis
    • COI: 1:CAS:528:DC%2BC3sXhsFSqs7rK, PID: 24058536
    • Arshad MI, Patrat-Delon S, Piquet-Pellorce C, L’Helgoualc’h A, Rauch M, Genet V et al (2013) Pathogenic mouse hepatitis virus or poly(I:C) induce IL-33 in hepatocytes in murine models of hepatitis. PLoS One 8:e74278
    • (2013) PLoS One , vol.8 , pp. e74278
    • Arshad, M.I.1    Patrat-Delon, S.2    Piquet-Pellorce, C.3    L’Helgoualc’h, A.4    Rauch, M.5    Genet, V.6
  • 26
    • 84867186211 scopus 로고    scopus 로고
    • Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice
    • COI: 1:CAS:528:DC%2BC38XhsVKmur3J, PID: 22782692
    • Sakai N, Van Sweringen HL, Quillin RC, Schuster R, Blanchard J, Burns JM et al (2012) Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice. Hepatology 56:1468–1478
    • (2012) Hepatology , vol.56 , pp. 1468-1478
    • Sakai, N.1    Van Sweringen, H.L.2    Quillin, R.C.3    Schuster, R.4    Blanchard, J.5    Burns, J.M.6
  • 27
    • 84870512750 scopus 로고    scopus 로고
    • Tumor necrosis factor related apoptosis inducing ligand (TRAIL), but not FasL and tumor necrosis factor alpha (TNFa), regulates interleukin (IL)-33 expression in murine hepatocytes during acute hepatitis
    • COI: 1:CAS:528:DC%2BC38XhvVSmtb3E, PID: 22961755
    • Arshad MI, Piquet-Pellorce C, L’Helgoualc’h A, Rauch M, Patrat-Delon S, Ezan F et al (2012) Tumor necrosis factor related apoptosis inducing ligand (TRAIL), but not FasL and tumor necrosis factor alpha (TNFa), regulates interleukin (IL)-33 expression in murine hepatocytes during acute hepatitis. Hepatology 56:2353–2362
    • (2012) Hepatology , vol.56 , pp. 2353-2362
    • Arshad, M.I.1    Piquet-Pellorce, C.2    L’Helgoualc’h, A.3    Rauch, M.4    Patrat-Delon, S.5    Ezan, F.6
  • 28
    • 33846101552 scopus 로고    scopus 로고
    • IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo
    • COI: 1:CAS:528:DC%2BD2sXjt12msw%3D%3D, PID: 17185418
    • Carriere V, Roussel L, Ortega N, Lacorre DA, Americh L, Aguilar L et al (2007) IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo. Proc Natl Acad Sci U S A 104:282–287
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 282-287
    • Carriere, V.1    Roussel, L.2    Ortega, N.3    Lacorre, D.A.4    Americh, L.5    Aguilar, L.6
  • 29
    • 36749067367 scopus 로고    scopus 로고
    • IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells
    • COI: 1:CAS:528:DC%2BD2sXhtl2ku7bO, PID: 18003919
    • Ali S, Huber M, Kollewe C, Bischoff SC, Falk W, Martin MU (2007) IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells. Proc Natl Acad Sci U S A 104:18660–18665
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 18660-18665
    • Ali, S.1    Huber, M.2    Kollewe, C.3    Bischoff, S.C.4    Falk, W.5    Martin, M.U.6
  • 30
  • 31
    • 68249143387 scopus 로고    scopus 로고
    • IL-33 raises alarm
    • COI: 1:CAS:528:DC%2BD1MXpsFOgtbk%3D, PID: 19604486
    • Lamkanfi M, Dixit VM (2009) IL-33 raises alarm. Immunity 31:5–7
    • (2009) Immunity , vol.31 , pp. 5-7
    • Lamkanfi, M.1    Dixit, V.M.2
  • 32
    • 67049158193 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
    • COI: 1:CAS:528:DC%2BD1MXntlyhtbY%3D, PID: 19439663
    • Cayrol C, Girard JP (2009) The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc Natl Acad Sci U S A 106:9021–9026
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9021-9026
    • Cayrol, C.1    Girard, J.P.2
  • 33
    • 68249137289 scopus 로고    scopus 로고
    • Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
    • COI: 1:CAS:528:DC%2BD1MXpsFOgurk%3D, PID: 19559631
    • Luthi AU, Cullen SP, McNeela EA, Duriez PJ, Afonina IS, Sheridan C et al (2009) Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 31:84–98
    • (2009) Immunity , vol.31 , pp. 84-98
    • Luthi, A.U.1    Cullen, S.P.2    McNeela, E.A.3    Duriez, P.J.4    Afonina, I.S.5    Sheridan, C.6
  • 34
    • 67651053209 scopus 로고    scopus 로고
    • Interleukin-33 is biologically active independently of caspase-1 cleavage
    • COI: 1:CAS:528:DC%2BD1MXot12kuro%3D, PID: 19465481
    • Talabot-Ayer D, Lamacchia C, Gabay C, Palmer G (2009) Interleukin-33 is biologically active independently of caspase-1 cleavage. J Biol Chem 284:19420–19426
    • (2009) J Biol Chem , vol.284 , pp. 19420-19426
    • Talabot-Ayer, D.1    Lamacchia, C.2    Gabay, C.3    Palmer, G.4
  • 35
    • 73949088791 scopus 로고    scopus 로고
    • Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation
    • COI: 1:CAS:528:DC%2BC3cXot1ymtw%3D%3D, PID: 20035719
    • Ali S, Nguyen DQ, Falk W, Martin MU (2010) Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation. Biochem Biophys Res Commun 391:1512–1516
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1512-1516
    • Ali, S.1    Nguyen, D.Q.2    Falk, W.3    Martin, M.U.4
  • 36
    • 70349305527 scopus 로고    scopus 로고
    • CX3CL1/fractalkine shedding by human hepatic stellate cells: contribution to chronic inflammation in the liver
    • COI: 1:CAS:528:DC%2BD1MXhtlGns7fM, PID: 19432809
    • Bourd-Boittin K, Basset L, Bonnier D, L’Helgoualc’h A, Samson M, Theret N (2009) CX3CL1/fractalkine shedding by human hepatic stellate cells: contribution to chronic inflammation in the liver. J Cell Mol Med 13:1526–1535
    • (2009) J Cell Mol Med , vol.13 , pp. 1526-1535
    • Bourd-Boittin, K.1    Basset, L.2    Bonnier, D.3    L’Helgoualc’h, A.4    Samson, M.5    Theret, N.6
  • 37
    • 79957566790 scopus 로고    scopus 로고
    • Invariant natural killer T-cell-deficient mice display increased CCl(4)-induced hepatitis associated with CXCL1 over-expression and neutrophil infiltration
    • COI: 1:CAS:528:DC%2BC3MXmsFGjurw%3D, PID: 21469102
    • Lisbonne M, L’Helgoualc’h A, Nauwelaers G, Turlin B, Lucas C, Herbelin A et al (2011) Invariant natural killer T-cell-deficient mice display increased CCl(4)-induced hepatitis associated with CXCL1 over-expression and neutrophil infiltration. Eur J Immunol 41:1720–1732
    • (2011) Eur J Immunol , vol.41 , pp. 1720-1732
    • Lisbonne, M.1    L’Helgoualc’h, A.2    Nauwelaers, G.3    Turlin, B.4    Lucas, C.5    Herbelin, A.6
  • 39
    • 80053087284 scopus 로고    scopus 로고
    • Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity
    • COI: 1:CAS:528:DC%2BC3MXht1Gqt7zJ, PID: 21876153
    • Lu JV, Weist BM, van Raam BJ, Marro BS, Nguyen LV, Srinivas P et al (2011) Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity. Proc Natl Acad Sci U S A 108:15312–15317
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 15312-15317
    • Lu, J.V.1    Weist, B.M.2    van Raam, B.J.3    Marro, B.S.4    Nguyen, L.V.5    Srinivas, P.6
  • 41
    • 33644840693 scopus 로고    scopus 로고
    • Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
    • COI: 1:CAS:528:DC%2BD2MXls1OmsLg%3D, PID: 16408008
    • Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N et al (2005) Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1:112–119
    • (2005) Nat Chem Biol , vol.1 , pp. 112-119
    • Degterev, A.1    Huang, Z.2    Boyce, M.3    Li, Y.4    Jagtap, P.5    Mizushima, N.6
  • 42
    • 80052850704 scopus 로고    scopus 로고
    • FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
    • COI: 1:CAS:528:DC%2BC3MXhtFersLrF, PID: 21804564
    • Welz PS, Wullaert A, Vlantis K, Kondylis V, Fernandez-Majada V, Ermolaeva M et al (2011) FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 477:330–334
    • (2011) Nature , vol.477 , pp. 330-334
    • Welz, P.S.1    Wullaert, A.2    Vlantis, K.3    Kondylis, V.4    Fernandez-Majada, V.5    Ermolaeva, M.6
  • 43
    • 80052845560 scopus 로고    scopus 로고
    • Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
    • PID: 21921917
    • Gunther C, Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H et al (2011) Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis. Nature 477:335–339
    • (2011) Nature , vol.477 , pp. 335-339
    • Gunther, C.1    Martini, E.2    Wittkopf, N.3    Amann, K.4    Weigmann, B.5    Neumann, H.6
  • 44
    • 84872382300 scopus 로고    scopus 로고
    • ARC is a novel therapeutic approach against acetaminophen-induced hepatocellular necrosis
    • COI: 1:CAS:528:DC%2BC3sXovFCguw%3D%3D, PID: 23046676
    • An J, Mehrhof F, Harms C, Lattig-Tunnemann G, Lee SL, Endres M et al (2013) ARC is a novel therapeutic approach against acetaminophen-induced hepatocellular necrosis. J Hepatol 58:297–305
    • (2013) J Hepatol , vol.58 , pp. 297-305
    • An, J.1    Mehrhof, F.2    Harms, C.3    Lattig-Tunnemann, G.4    Lee, S.L.5    Endres, M.6
  • 45
    • 84907751865 scopus 로고    scopus 로고
    • Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure
    • COI: 1:CAS:528:DC%2BC2cXhsFCis7fO, PID: 25349782
    • Takemoto K, Hatano E, Iwaisako K, Takeiri M, Noma N, Ohmae S et al (2014) Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure. FEBS open bio 4:777–787
    • (2014) FEBS open bio , vol.4 , pp. 777-787
    • Takemoto, K.1    Hatano, E.2    Iwaisako, K.3    Takeiri, M.4    Noma, N.5    Ohmae, S.6
  • 46
    • 84893653487 scopus 로고    scopus 로고
    • Role of receptor interacting protein (RIP)1 on apoptosis-inducing factor-mediated necroptosis during acetaminophen-evoked acute liver failure in mice
    • COI: 1:CAS:528:DC%2BC2cXivFCktLc%3D, PID: 24440347
    • Zhang YF, He W, Zhang C, Liu XJ, Lu Y, Wang H et al (2014) Role of receptor interacting protein (RIP)1 on apoptosis-inducing factor-mediated necroptosis during acetaminophen-evoked acute liver failure in mice. Toxicol Lett 225:445–453
    • (2014) Toxicol Lett , vol.225 , pp. 445-453
    • Zhang, Y.F.1    He, W.2    Zhang, C.3    Liu, X.J.4    Lu, Y.5    Wang, H.6
  • 47
    • 32044447161 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover
    • COI: 1:CAS:528:DC%2BD28Xhslaqs7c%3D, PID: 16469705
    • Chang L, Kamata H, Solinas G, Luo JL, Maeda S, Venuprasad K et al (2006) The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover. Cell 124:601–613
    • (2006) Cell , vol.124 , pp. 601-613
    • Chang, L.1    Kamata, H.2    Solinas, G.3    Luo, J.L.4    Maeda, S.5    Venuprasad, K.6
  • 48
    • 58149262908 scopus 로고    scopus 로고
    • Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim
    • COI: 1:CAS:528:DC%2BD1MXhtlCnsL8%3D, PID: 19119023
    • Kaufmann T, Jost PJ, Pellegrini M, Puthalakath H, Gugasyan R, Gerondakis S et al (2009) Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim. Immunity 30:56–66
    • (2009) Immunity , vol.30 , pp. 56-66
    • Kaufmann, T.1    Jost, P.J.2    Pellegrini, M.3    Puthalakath, H.4    Gugasyan, R.5    Gerondakis, S.6
  • 49
    • 81255195542 scopus 로고    scopus 로고
    • Programmed necrosis: backup to and competitor with apoptosis in the immune system
    • COI: 1:CAS:528:DC%2BC3MXhsVOisbjN, PID: 22089220
    • Han J, Zhong CQ, Zhang DW (2011) Programmed necrosis: backup to and competitor with apoptosis in the immune system. Nat Immunol 12:1143–1149
    • (2011) Nat Immunol , vol.12 , pp. 1143-1149
    • Han, J.1    Zhong, C.Q.2    Zhang, D.W.3
  • 50
    • 0028795171 scopus 로고
    • Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor
    • COI: 1:CAS:528:DyaK2MXjs1ygsLY%3D, PID: 7806154
    • Gantner F, Leist M, Lohse AW, Germann PG, Tiegs G (1995) Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 21:190–198
    • (1995) Hepatology , vol.21 , pp. 190-198
    • Gantner, F.1    Leist, M.2    Lohse, A.W.3    Germann, P.G.4    Tiegs, G.5
  • 51
    • 0030017301 scopus 로고    scopus 로고
    • Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A
    • COI: 1:STN:280:DyaK28zgsFWitA%3D%3D, PID: 8690213
    • Kusters S, Gantner F, Kunstle G, Tiegs G (1996) Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A. Gastroenterology 111:462–471
    • (1996) Gastroenterology , vol.111 , pp. 462-471
    • Kusters, S.1    Gantner, F.2    Kunstle, G.3    Tiegs, G.4
  • 52
    • 84255162817 scopus 로고    scopus 로고
    • Necroptosis turns TNF lethal
    • COI: 1:CAS:528:DC%2BC3MXhs1KrtrbE, PID: 22195740
    • Galluzzi L, Kroemer G (2011) Necroptosis turns TNF lethal. Immunity 35:849–851
    • (2011) Immunity , vol.35 , pp. 849-851
    • Galluzzi, L.1    Kroemer, G.2
  • 53
    • 84862943893 scopus 로고    scopus 로고
    • Immune mechanisms of Concanavalin A model of autoimmune hepatitis
    • COI: 1:CAS:528:DC%2BC38XhslKnsbo%3D, PID: 22253517
    • Wang HX, Liu M, Weng SY, Li JJ, Xie C, He HL et al (2012) Immune mechanisms of Concanavalin A model of autoimmune hepatitis. World J Gastroenterol 18:119–125
    • (2012) World J Gastroenterol , vol.18 , pp. 119-125
    • Wang, H.X.1    Liu, M.2    Weng, S.Y.3    Li, J.J.4    Xie, C.5    He, H.L.6
  • 55
    • 63149121152 scopus 로고    scopus 로고
    • Circulating microRNAs, potential biomarkers for drug-induced liver injury
    • COI: 1:CAS:528:DC%2BD1MXjslyhsL4%3D, PID: 19246379
    • Wang K, Zhang S, Marzolf B, Troisch P, Brightman A, Hu Z et al (2009) Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc Natl Acad Sci U S A 106:4402–4407
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 4402-4407
    • Wang, K.1    Zhang, S.2    Marzolf, B.3    Troisch, P.4    Brightman, A.5    Hu, Z.6
  • 56
    • 78649837734 scopus 로고    scopus 로고
    • Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases
    • COI: 1:CAS:528:DC%2BC3cXhsF2js7%2FF, PID: 20930130
    • Zhang Y, Jia Y, Zheng R, Guo Y, Wang Y, Guo H et al (2010) Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases. Clin Chem 56:1830–1838
    • (2010) Clin Chem , vol.56 , pp. 1830-1838
    • Zhang, Y.1    Jia, Y.2    Zheng, R.3    Guo, Y.4    Wang, Y.5    Guo, H.6
  • 57
    • 84868211262 scopus 로고    scopus 로고
    • Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases
    • PID: 22684891
    • Bala S, Petrasek J, Mundkur S, Catalano D, Levin I, Ward J et al (2012) Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. Hepatology. doi:10.1002/hep.25873
    • (2012) Hepatology
    • Bala, S.1    Petrasek, J.2    Mundkur, S.3    Catalano, D.4    Levin, I.5    Ward, J.6
  • 58
    • 4043136609 scopus 로고    scopus 로고
    • The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2
    • COI: 1:CAS:528:DC%2BD2cXmtFOisb4%3D, PID: 15175328
    • Lee TH, Shank J, Cusson N, Kelliher MA (2004) The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2. J Biol Chem 279:33185–33191
    • (2004) J Biol Chem , vol.279 , pp. 33185-33191
    • Lee, T.H.1    Shank, J.2    Cusson, N.3    Kelliher, M.A.4
  • 59
    • 42249102086 scopus 로고    scopus 로고
    • Identification of RIP1 kinase as a specific cellular target of necrostatins
    • COI: 1:CAS:528:DC%2BD1cXkvVSmtL0%3D, PID: 18408713
    • Degterev A, Hitomi J, Germscheid M, Ch’en IL, Korkina O, Teng X et al (2008) Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 4:313–321
    • (2008) Nat Chem Biol , vol.4 , pp. 313-321
    • Degterev, A.1    Hitomi, J.2    Germscheid, M.3    Ch’en, I.L.4    Korkina, O.5    Teng, X.6
  • 60
    • 0028917669 scopus 로고
    • Human Kupffer cells secrete IL-10 in response to lipopolysaccharide (LPS) challenge
    • COI: 1:CAS:528:DyaK2MXmt1OntrY%3D, PID: 7790711
    • Knolle P, Schlaak J, Uhrig A, Kempf P, Meyer zum Buschenfelde KH, Gerken G (1995) Human Kupffer cells secrete IL-10 in response to lipopolysaccharide (LPS) challenge. J Hepatol 22:226–229
    • (1995) J Hepatol , vol.22 , pp. 226-229
    • Knolle, P.1    Schlaak, J.2    Uhrig, A.3    Kempf, P.4    Meyer zum Buschenfelde, K.H.5    Gerken, G.6


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