Pathogenic Mouse Hepatitis Virus or Poly(I:C) Induce IL-33 in Hepatocytes in Murine Models of Hepatitis

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Arshad, Muhammad Imran ^a,b,c,e   Patrat Delon, Solène ^a,b,c   Piquet Pellorce, Claire ^a,b,c   L'Helgoualc'h, Annie ^a,b,c   Rauch, Michel ^a,b,c   Genet, Valentine ^a,b,c   Lucas Clerc, Catherine ^b   Bleau, Christian ^d   Lamontagne, Lucie ^d   Samson, Michel ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c UNIVERSITÉ DE RENNES 1   (France)

^d UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^e UNIVERSITY OF AGRICULTURE   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

CD1D ANTIGEN; GALACTOSAMINE; INTERLEUKIN 33; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MODEL; DOWN REGULATION; ENDOTHELIUM CELL; GENE OVEREXPRESSION; HEPATITIS; KNOCKOUT MOUSE; LIVER CELL; LIVER SINUSOID; MICROENVIRONMENT; MOUSE; MURINE HEPATITIS CORONAVIRUS; NATURAL KILLER CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; UPREGULATION; VASCULAR ENDOTHELIUM; VIRUS VIRULENCE; WILD TYPE;

ANIMALS; ANTIGENS, CD1D; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GALACTOSAMINE; GENE DELETION; GENE EXPRESSION; HEPATITIS; HEPATITIS, VIRAL, ANIMAL; INTERLEUKINS; KILLER CELLS, NATURAL; LIVER; MICE; MICE, KNOCKOUT; MURINE HEPATITIS VIRUS; NATURAL KILLER T-CELLS; POLY I-C;

EID: 84884168728     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074278     Document Type: Article

References (34)

1. Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, et al. (2005) IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23: 479-490. doi:10.1016/j.immuni.2005.09.015. PubMed: 16286016.
2. Ali S, Huber M, Kollewe C, Bischoff SC, Falk W, et al. (2007) IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells. Proc Natl Acad Sci U S A 104: 18660-18665. doi:10.1073/pnas.0705939104. PubMed: 18003919.
3. Liew FY, Pitman NI, McInnes IB, (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nat Rev Immunol 10: 103-110. doi:10.1038/nri2692. PubMed: 20081870.
4. Liew FY, (2012) IL-33: a Janus cytokine. Ann Rheum Dis 71 Suppl 2: i101-i104 doi:10.1136/annrheumdis-2011-200589. PubMed: 22460136.
5. Le Goffic R, Arshad MI, Rauch M, L'Helgoualc'h A, Delmas B, et al. (2011) Infection with influenza virus induces IL-33 in murine lungs. Am J Respir Cell Mol Biol 45: 1125-1132. doi:10.1165/rcmb.2010-0516OC. PubMed: 21642589.
6. Chang YJ, Kim HY, Albacker LA, Baumgarth N, McKenzie AN, et al. (2011) Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. Nat Immunol 12: 631-638. doi:10.1038/ni.2045. PubMed: 21623379.
7. Bonilla WV, Fröhlich A, Senn K, Kallert S, Fernandez M, et al. (2012) The alarmin interleukin-33 drives protective antiviral CD8(+) T cell responses. Science 335: 984-989. doi:10.1126/science.1215418. PubMed: 22323740.
8. Becerra A, Warke RV, de Bosch N, Rothman AL, Bosch I, (2008) Elevated levels of soluble ST2 protein in dengue virus infected patients. Cytokine 41: 114-120. doi:10.1016/j.cyto.2007.11.001. PubMed: 18226917.
9. Miyagaki T, Sugaya M, Yokobayashi H, Kato T, Ohmatsu H, et al. (2011) High levels of soluble ST2 and low levels of IL-33 in sera of patients with HIV infection. J Invest Dermatol 131: 794-796. doi:10.1038/jid.2010.366. PubMed: 21150924.
10. Arshad MI, Rauch M, L'Helgoualc'h A, Julia V, Leite-de-Moraes MC, et al. (2011) NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis. Eur J Immunol 41: 2341-2348. doi:10.1002/eji.201041332. PubMed: 21557213.
11. Arshad MI, Piquet-Pellorce C, Samson M, (2012) IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology. Liver Int, 32: 1200-10. PubMed: 22530772.
12. Volarevic V, Mitrovic M, Milovanovic M, Zelen I, Nikolic I, et al. (2012) Protective role of IL-33/ST2 axis in Con A-induced hepatitis. J Hepatol 56: 26-33. doi:10.1016/S0168-8278(12)60072-5. PubMed: 21703183.
13. Arshad MI, Piquet-Pellorce C, L'Helgoualc'h A, Rauch M, Patrat-Delon S, et al. (2012) Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL), but Not FasL and Tumor Necrosis Factor alpha (TNFa), Regulates Interleukin (IL)-33 Expression in Murine Hepatocytes During Acute Hepatitis. Hepatology 56: 2353-2362. doi:10.1002/hep.25893. PubMed: 22961755.
14. Marvie P, Lisbonne M, L'Helgoualc'h A, Rauch M, Turlin B, et al. (2010) Interleukin-33 overexpression is associated with liver fibrosis in mice and humans. J Cell Mol Med 14: 1726-1739. PubMed: 19508382.
15. Roth GA, Zimmermann M, Lubsczyk BA, Pilz J, Faybik P, et al. (2010) Up-regulation of interleukin 33 and soluble ST2 serum levels in liver failure. J Surg Res 163: e79-e83. doi:10.1016/j.jss.2010.04.004. PubMed: 20638676.
16. Wang J, Zhao P, Guo H, Sun X, Jiang Z, et al. (2012) Serum IL-33 levels are associated with liver damage in patients with chronic hepatitis C. Mediat Inflamm, 2012(2012): 819636. PubMed: 22315510.
17. Wang J, Cai Y, Ji H, Feng J, Ayana DA, et al. (2012) Serum IL-33 Levels Are Associated with Liver Damage in Patients with Chronic Hepatitis B. J Interferon Cytokine Res 32: 248-253. doi:10.1089/jir.2011.0109. PubMed: 22304300.
18. Alexopoulou L, Holt AC, Medzhitov R, Flavell RA, (2001) Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413: 732-738. doi:10.1038/35099560. PubMed: 11607032.
19. Dejager L, Libert C, (2008) Tumor necrosis factor alpha mediates the lethal hepatotoxic effects of poly(I:C) in D-galactosamine-sensitized mice. Cytokine 42: 55-61. doi:10.1016/j.cyto.2008.01.014. PubMed: 18331798.
20. Cavanaugh PF Jr., Ho YK, Bardos TJ, (1996) The activation of murine macrophages and natural killer cells by the partially thiolated double stranded RNA poly(I)-mercapto poly(C). Res Commun Mol Pathol Pharmacol 91: 131-147. PubMed: 8832906.
21. Schwabe RF, Seki E, Brenner DA, (2006) Toll-like receptor signaling in the liver. Gastroenterology 130: 1886-1900. doi:10.1053/j.gastro.2006.01.038. PubMed: 16697751.
22. Hou X, Zhou R, Wei H, Sun R, Tian Z, (2009) NKG2D-retinoic acid early inducible-1 recognition between natural killer cells and Kupffer cells in a novel murine natural killer cell-dependent fulminant hepatitis. Hepatology 49: 940-949. doi:10.1002/hep.22725. PubMed: 19177594.
23. Lamontagne L, Descoteaux JP, Jolicoeur P, (1989) Mouse hepatitis virus 3 replication in T and B lymphocytes correlate with viral pathogenicity. J Immunol 142: 4458-4465. PubMed: 2542412.
24. Aparicio JL, Peña C, Retegui LA, (2011) Autoimmune hepatitis-like disease in C57BL/6 mice infected with mouse hepatitis virus A59. Int Immunopharmacol 11: 1591-1598. doi:10.1016/j.intimp.2011.05.020. PubMed: 21635973.
25. Jacques A, Bleau C, Martin JP, Lamontagne L, (2008) Intrahepatic endothelial and Kupffer cells involved in immunosuppressive cytokines and natural killer (NK)/NK T cell disorders in viral acute hepatitis. Clin Exp Immunol 152: 298-310. doi:10.1111/j.1365-2249.2008.03628.x. PubMed: 18336588.
26. Godfraind C, Langreth SG, Cardellichio CB, Knobler R, Coutelier JP, et al. (1995) Tissue and cellular distribution of an adhesion molecule in the carcinoembryonic antigen family that serves as a receptor for mouse hepatitis virus. Lab Invest 73: 615-627. PubMed: 7474935.
27. Lehoux M, Jacques A, Lusignan S, Lamontagne L, (2004) Murine viral hepatitis involves NK cell depletion associated with virus-induced apoptosis. Clin Exp Immunol 137: 41-51. doi:10.1111/j.1365-2249.2004.02501.x. PubMed: 15196242.
28. Jacques A, Bleau C, Turbide C, Beauchemin N, Lamontagne L, (2009) Macrophage interleukin-6 and tumour necrosis factor-alpha are induced by coronavirus fixation to Toll-like receptor 2/heparan sulphate receptors but not carcinoembryonic cell adhesion antigen 1a. Immunology 128: e181-e192. doi:10.1111/j.1365-2567.2008.02946.x. PubMed: 19740307.
29. Lisbonne M, L'Helgoualc'h A, Nauwelaers G, Turlin B, Lucas C, et al. (2011) Invariant natural killer T-cell-deficient mice display increased CCl(4)-induced hepatitis associated with CXCL1 over-expression and neutrophil infiltration. Eur J Immunol 41: 1720-1732. doi:10.1002/eji.201041006. PubMed: 21469102.
30. Zhang L, Lu R, Zhao G, Pflugfelder SC, Li DQ, (2011) TLR-mediated induction of pro-allergic cytokine IL-33 in ocular mucosal epithelium. Int J Biochem Cell Biol 43: 1383-1391. doi:10.1016/j.biocel.2011.06.003. PubMed: 21684348.
31. Sponheim J, Pollheimer J, Olsen T, Balogh J, Hammarström C, et al. (2010) Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts. Am J Pathol 177: 2804-2815. doi:10.2353/ajpath.2010.100378. PubMed: 21037074.
32. Polumuri SK, Jayakar GG, Shirey KA, Roberts ZJ, Perkins DJ, et al. (2012) Transcriptional Regulation of Murine IL-33 by TLR and Non-TLR Agonists. J Immunol, 189: 50-60. PubMed: 22634618.
33. Stefanovic L, Brenner DA, Stefanovic B, (2005) Direct hepatotoxic effect of KC chemokine in the liver without infiltration of neutrophils. Exp Biol Med (Maywood) 230: 573-586. PubMed: 16118408.
34. Patrick AL, Rullo J, Beaudin S, Liaw P, Fox-Robichaud AE, (2007) Hepatic leukocyte recruitment in response to time-limited expression of TNF-alpha and IL-1beta. Am J Physiol Gastrointest Liver Physiol 293: G663-G672. doi:10.1152/ajpgi.00070.2007. PubMed: 17656447.