-
1
-
-
84929620816
-
CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2007-2011
-
Ostrom QT, Gittleman H, Liao P, et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro-Oncol 2014; 16(Suppl 4):iv1-63
-
(2014)
Neuro-Oncol
, vol.16
, pp. iv1-63
-
-
Ostrom, Q.T.1
Gittleman, H.2
Liao, P.3
-
2
-
-
34347207046
-
-
4th Revised Edition. World Health Organization; Geneva, Switzerland
-
Cancer IA for R on, Cavenee WK, Ohgaki H, Wiestler OD, Louis DN. WHO Classification of tumours of the central nervous system. 4th Revised Edition. World Health Organization; Geneva, Switzerland: 2007
-
(2007)
WHO Classification of Tumours of the Central Nervous System
-
-
Cavenee, W.K.1
Ohgaki, H.2
Wiestler, O.D.3
Louis, D.N.4
-
3
-
-
43049124130
-
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas
-
Pfister S, Janzarik WG, Remke M, et al. BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. J Clin Invest 2008; 118(5):1739-49
-
(2008)
J Clin Invest
, vol.118
, Issue.5
, pp. 1739-1749
-
-
Pfister, S.1
Janzarik, W.G.2
Remke, M.3
-
4
-
-
27144540888
-
RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma
-
Sharma MK, Zehnbauer BA, Watson MA, Gutmann DH. RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma. Neurology 2005; 65(8):1335-6
-
(2005)
Neurology
, vol.65
, Issue.8
, pp. 1335-1336
-
-
Sharma, M.K.1
Zehnbauer, B.A.2
Watson, M.A.3
Gutmann, D.H.4
-
5
-
-
73649119176
-
MAPK pathway activation and the origins of pediatric low-grade astrocytomas
-
Tatevossian RG, Lawson AR, Forshew T, et al. MAPK pathway activation and the origins of pediatric low-grade astrocytomas. J Cell Physiol 2010;222(3):509-14
-
(2010)
J Cell Physiol
, vol.222
, Issue.3
, pp. 509-514
-
-
Tatevossian, R.G.1
Lawson, A.R.2
Forshew, T.3
-
6
-
-
0033864837
-
Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas
-
Gutmann DH, Donahoe J, Brown T, et al. Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas. Neuropathol Appl Neurobiol 2000;26(4):361-7
-
(2000)
Neuropathol Appl Neurobiol
, vol.26
, Issue.4
, pp. 361-367
-
-
Gutmann, D.H.1
Donahoe, J.2
Brown, T.3
-
7
-
-
33644761901
-
Molecular genetic analyses in neurofibromatosis type 1 patients with tumors
-
Oguzkan S, Terzi YK, Cinbis M, et al. Molecular genetic analyses in neurofibromatosis type 1 patients with tumors. Cancer Genet Cytogenet 2006; 165(2):167-71
-
(2006)
Cancer Genet Cytogenet
, vol.165
, Issue.2
, pp. 167-171
-
-
Oguzkan, S.1
Terzi, Y.K.2
Cinbis, M.3
-
8
-
-
72049096346
-
Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma
-
Yu J, Deshmukh H, Gutmann RJ, et al. Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma. Neurology 2009;73(19): 1526-31
-
(2009)
Neurology
, vol.73
, Issue.19
, pp. 1526-1531
-
-
Yu, J.1
Deshmukh, H.2
Gutmann, R.J.3
-
9
-
-
52649172327
-
Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma
-
Bar EE, Lin A, Tihan T, et al. Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma. J Neuropathol Exp Neurol 2008;67(9):878-87
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, Issue.9
, pp. 878-887
-
-
Bar, E.E.1
Lin, A.2
Tihan, T.3
-
10
-
-
66949147222
-
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene
-
Sievert AJ, Jackson EM, Gai X, et al. Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. Brain Pathol 2009;19(3): 449-58
-
(2009)
Brain Pathol
, vol.19
, Issue.3
, pp. 449-458
-
-
Sievert, A.J.1
Jackson, E.M.2
Gai, X.3
-
11
-
-
55349107544
-
Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
-
Jones DT, Kocialkowski S, Liu L, et al. Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Cancer Res 2008;68(21):8673-7
-
(2008)
Cancer Res
, vol.68
, Issue.21
, pp. 8673-8677
-
-
Jones, D.T.1
Kocialkowski, S.2
Liu, L.3
-
12
-
-
78349232314
-
MAPK pathway activation through BRAF gene fusion in pilocytic astrocytomas; A novel oncogenic fusion gene with diagnostic, prognostic, and therapeutic potential
-
Jeuken JW, Wesseling P. MAPK pathway activation through BRAF gene fusion in pilocytic astrocytomas; a novel oncogenic fusion gene with diagnostic, prognostic, and therapeutic potential. J Pathol 2010;222(4): 324-8
-
(2010)
J Pathol
, vol.222
, Issue.4
, pp. 324-328
-
-
Jeuken, J.W.1
Wesseling, P.2
-
13
-
-
68749098096
-
Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours
-
Jacob K, Albrecht S, Sollier C, et al. Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours. Br J Cancer 2009;101(4):722-33
-
(2009)
Br J Cancer
, vol.101
, Issue.4
, pp. 722-733
-
-
Jacob, K.1
Albrecht, S.2
Sollier, C.3
-
14
-
-
80052273582
-
Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma
-
Eisenhardt AE, Olbrich H, Röring M, et al. Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma. Int J Cancer J 2011;129(9): 2297-303
-
(2011)
Int J Cancer J
, vol.129
, Issue.9
, pp. 2297-2303
-
-
Eisenhardt, A.E.1
Olbrich, H.2
Röring, M.3
-
15
-
-
79954441895
-
Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
-
Schindler G, Capper D, Meyer J, et al. Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathol 2011;121(3):397-405
-
(2011)
Acta Neuropathol
, vol.121
, Issue.3
, pp. 397-405
-
-
Schindler, G.1
Capper, D.2
Meyer, J.3
-
16
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty KT, Puzanov I, Kim KB, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 2010; 363(9):809-19
-
(2010)
N Engl J Med
, vol.363
, Issue.9
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
-
17
-
-
84906075553
-
Mechanism and consequences of RAF kinase activation by small-molecule inhibitors
-
Holderfield M, Nagel TE, Stuart DD. Mechanism and consequences of RAF kinase activation by small-molecule inhibitors. Br J Cancer 2014;111(4):640-5
-
(2014)
Br J Cancer
, vol.111
, Issue.4
, pp. 640-645
-
-
Holderfield, M.1
Nagel, T.E.2
Stuart, D.D.3
-
18
-
-
84925547021
-
Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib
-
Idbaih A, Mokhtari K, Emile JF, et al. Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib. Neurology 2014; 83(16):1478-80
-
(2014)
Neurology
, vol.83
, Issue.16
, pp. 1478-1480
-
-
Idbaih, A.1
Mokhtari, K.2
Emile, J.F.3
-
19
-
-
84880983541
-
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
-
Jones DTW, Hutter B, Jäger N, et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat Genet 2013;45(8):927-32
-
(2013)
Nat Genet
, vol.45
, Issue.8
, pp. 927-932
-
-
Jones, D.T.W.1
Hutter, B.2
Jäger, N.3
-
20
-
-
57749091894
-
Clinicopathological features and global genomic copy number alterations of pilomyxoid astrocytoma in the hypothalamus/optic pathway: Comparative analysis with pilocytic astrocytoma using array-based comparative genomic hybridization
-
Jeon YK, Cheon JE, Kim SK, et al. Clinicopathological features and global genomic copy number alterations of pilomyxoid astrocytoma in the hypothalamus/optic pathway: comparative analysis with pilocytic astrocytoma using array-based comparative genomic hybridization. Mod Pathol 2008;21(11): 1345-56
-
(2008)
Mod Pathol
, vol.21
, Issue.11
, pp. 1345-1356
-
-
Jeon, Y.K.1
Cheon, J.E.2
Kim, S.K.3
-
21
-
-
84883647983
-
Outcome analysis of childhood pilocytic astrocytomas: A retrospective study of 148 cases at a single institution
-
Colin C, Padovani L, Chappe C, et al. Outcome analysis of childhood pilocytic astrocytomas: a retrospective study of 148 cases at a single institution. Neuropathol Appl Neurobiol 2013;39(6): 693-705
-
(2013)
Neuropathol Appl Neurobiol
, vol.39
, Issue.6
, pp. 693-705
-
-
Colin, C.1
Padovani, L.2
Chappe, C.3
-
22
-
-
4344688094
-
Clinico-pathological features of pilomyxoid astrocytoma of the optic pathway
-
Chikai K, Ohnishi A, Kato T, et al. Clinico-pathological features of pilomyxoid astrocytoma of the optic pathway. Acta Neuropathol 2004;108(2):109-14
-
(2004)
Acta Neuropathol
, vol.108
, Issue.2
, pp. 109-114
-
-
Chikai, K.1
Ohnishi, A.2
Kato, T.3
-
23
-
-
84907291101
-
Pilomyxoid astrocytoma treated successfully with vemurafenib
-
Skrypek M, Foreman N, Guillaume D, Moertel C. Pilomyxoid astrocytoma treated successfully with vemurafenib. Pediatr Blood Cancer 2014;61(11):2099-100
-
(2014)
Pediatr Blood Cancer
, vol.61
, Issue.11
, pp. 2099-2100
-
-
Skrypek, M.1
Foreman, N.2
Guillaume, D.3
Moertel, C.4
-
24
-
-
84925231101
-
Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study
-
Franz DN, Belousova E, Sparagana S, et al. Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study. Lancet Oncol 2014;15(13):1513-20
-
(2014)
Lancet Oncol
, vol.15
, Issue.13
, pp. 1513-1520
-
-
Franz, D.N.1
Belousova, E.2
Sparagana, S.3
-
25
-
-
84872088946
-
Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): A multicentre, randomised, placebo-controlled phase 3 trial
-
Franz DN, Belousova E, Sparagana S, et al. Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial. Lancet 2013;381(9861):125-32
-
(2013)
Lancet
, vol.381
, Issue.9861
, pp. 125-132
-
-
Franz, D.N.1
Belousova, E.2
Sparagana, S.3
-
26
-
-
78149249554
-
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
-
Houillier C, Wang X, Kaloshi G, et al. IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas. Neurology 2010;75(17): 1560-6
-
(2010)
Neurology
, vol.75
, Issue.17
, pp. 1560-1566
-
-
Houillier, C.1
Wang, X.2
Kaloshi, G.3
-
27
-
-
33750563258
-
A t (1;19)(q10;p10) Mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma
-
Jenkins RB, Blair H, Ballman KV, et al. A t (1;19)(q10;p10) Mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma. Cancer Res 2006; 66(20):9852-61
-
(2006)
Cancer Res
, vol.66
, Issue.20
, pp. 9852-9861
-
-
Jenkins, R.B.1
Blair, H.2
Ballman, K.V.3
-
28
-
-
0344863443
-
Chromosomal anomalies in oligodendroglial tumors are correlated with clinical features
-
Van den Bent MJ, Looijenga LH, Langenberg K, et al. Chromosomal anomalies in oligodendroglial tumors are correlated with clinical features. Cancer 2003;97(5):1276-84
-
(2003)
Cancer
, vol.97
, Issue.5
, pp. 1276-1284
-
-
Van Den Bent, M.J.1
Looijenga, L.H.2
Langenberg, K.3
-
29
-
-
19944411123
-
Correlations between molecular profile and radiologic pattern in oligodendroglial tumors
-
Laigle-Donadey F, Martin-Duverneuil N, Lejeune J, et al. Correlations between molecular profile and radiologic pattern in oligodendroglial tumors. Neurology 2004; 63(12):2360-2
-
(2004)
Neurology
, vol.63
, Issue.12
, pp. 2360-2362
-
-
Laigle-Donadey, F.1
Martin-Duverneuil, N.2
Lejeune, J.3
-
30
-
-
34848875420
-
Molecular genetic markers as predictors of response to chemotherapy in gliomas
-
Idbaih A, Omuro A, Ducray F, Hoang-Xuan K. Molecular genetic markers as predictors of response to chemotherapy in gliomas. Curr Opin Oncol 2007;19(6): 606-11
-
(2007)
Curr Opin Oncol
, vol.19
, Issue.6
, pp. 606-611
-
-
Idbaih, A.1
Omuro, A.2
Ducray, F.3
Hoang-Xuan, K.4
-
31
-
-
79960315686
-
Molecular markers in low-grade gliomas: Predictive or prognostic
-
Hartmann C, Hentschel B, Tatagiba M, et al. Molecular markers in low-grade gliomas: predictive or prognostic? Clin Cancer Res 2011;17(13):4588-99
-
(2011)
Clin Cancer Res
, vol.17
, Issue.13
, pp. 4588-4599
-
-
Hartmann, C.1
Hentschel, B.2
Tatagiba, M.3
-
32
-
-
34249013376
-
Temozolomide for low-grade gliomas: Predictive impact of 1p/19q loss on response and outcome
-
Kaloshi G, Benouaich-Amiel A, Diakite F, et al. Temozolomide for low-grade gliomas: predictive impact of 1p/19q loss on response and outcome. Neurology 2007; 68(21):1831-6
-
(2007)
Neurology
, vol.68
, Issue.21
, pp. 1831-1836
-
-
Kaloshi, G.1
Benouaich-Amiel, A.2
Diakite, F.3
-
33
-
-
33646061363
-
Progressive low-grade oligodendrogliomas: Response to temozolomide and correlation between genetic profile and O6-methylguanine DNA methyltransferase protein expression
-
Levin N, Lavon I, Zelikovitsh B, et al. Progressive low-grade oligodendrogliomas: response to temozolomide and correlation between genetic profile and O6-methylguanine DNA methyltransferase protein expression. Cancer 2006;106(8): 1759-65
-
(2006)
Cancer
, vol.106
, Issue.8
, pp. 1759-1765
-
-
Levin, N.1
Lavon, I.2
Zelikovitsh, B.3
-
34
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008; 321(5897):1807-12
-
(2008)
Science
, vol.321
, Issue.5897
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
35
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H, Parsons DW, Jin G, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med 2009;360(8):765-73
-
(2009)
N Engl J Med
, vol.360
, Issue.8
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
-
36
-
-
70249097408
-
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
-
Sanson M, Marie Y, Paris S, et al. Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol 2009;27(25):4150-4
-
(2009)
J Clin Oncol
, vol.27
, Issue.25
, pp. 4150-4154
-
-
Sanson, M.1
Marie, Y.2
Paris, S.3
-
37
-
-
77649305610
-
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
-
Ward PS, Patel J, Wise DR, et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 2010;17(3):225-34
-
(2010)
Cancer Cell
, vol.17
, Issue.3
, pp. 225-234
-
-
Ward, P.S.1
Patel, J.2
Wise, D.R.3
-
38
-
-
84858796262
-
IDH mutation impairs histone demethylation and results in a block to cell differentiation
-
Lu C, Ward PS, Kapoor GS, et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature 2012;483(7390):474-8
-
(2012)
Nature
, vol.483
, Issue.7390
, pp. 474-478
-
-
Lu, C.1
Ward, P.S.2
Kapoor, G.S.3
-
40
-
-
84877632013
-
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
-
Rohle D, Popovici-Muller J, Palaskas N, et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science 2013;340(6132): 626-30
-
(2013)
Science
, vol.340
, Issue.6132
, pp. 626-630
-
-
Rohle, D.1
Popovici-Muller, J.2
Palaskas, N.3
-
41
-
-
84886744421
-
Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine
-
Turcan S, Fabius AW, Borodovsky A, et al. Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine. Oncotarget 2013;4(10):1729-36
-
(2013)
Oncotarget
, vol.4
, Issue.10
, pp. 1729-1736
-
-
Turcan, S.1
Fabius, A.W.2
Borodovsky, A.3
-
42
-
-
84886741979
-
5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft
-
Borodovsky A, Salmasi V, Turcan S, et al. 5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft. Oncotarget 2013;4(10):1737-47
-
(2013)
Oncotarget
, vol.4
, Issue.10
, pp. 1737-1747
-
-
Borodovsky, A.1
Salmasi, V.2
Turcan, S.3
-
43
-
-
84906557615
-
A vaccine targeting mutant IDH1 induces antitumour immunity
-
Schumacher T, Bunse L, Pusch S, et al. A vaccine targeting mutant IDH1 induces antitumour immunity. Nature 2014; 512(7514):324-7
-
(2014)
Nature
, vol.512
, Issue.7514
, pp. 324-327
-
-
Schumacher, T.1
Bunse, L.2
Pusch, S.3
-
44
-
-
82755194965
-
Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers
-
Yip S, Butterfield YS, Morozova O, et al. Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. J Pathol 2012;226(1):7-16
-
(2012)
J Pathol
, vol.226
, Issue.1
, pp. 7-16
-
-
Yip, S.1
Butterfield, Y.S.2
Morozova, O.3
-
45
-
-
84866411339
-
CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas
-
Sahm F, Koelsche C, Meyer J, et al. CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas. Acta Neuropathol 2012; 123(6):853-60
-
(2012)
Acta Neuropathol
, vol.123
, Issue.6
, pp. 853-860
-
-
Sahm, F.1
Koelsche, C.2
Meyer, J.3
-
46
-
-
84868625787
-
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
-
Jiao Y, Killela PJ, Reitman ZJ, et al. Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget 2012;3(7): 709-22
-
(2012)
Oncotarget
, vol.3
, Issue.7
, pp. 709-722
-
-
Jiao, Y.1
Killela, P.J.2
Reitman, Z.J.3
-
47
-
-
84876067164
-
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
-
Killela PJ, Reitman ZJ, Jiao Y, et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proc Natl Acad Sci USA 2013;110(15): 6021-6
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.15
, pp. 6021-6026
-
-
Killela, P.J.1
Reitman, Z.J.2
Jiao, Y.3
-
48
-
-
84881095932
-
Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss
-
Arita H, Narita Y, Fukushima S, et al. Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss. Acta Neuropathol 2013;126(2):267-76
-
(2013)
Acta Neuropathol
, vol.126
, Issue.2
, pp. 267-276
-
-
Arita, H.1
Narita, Y.2
Fukushima, S.3
-
49
-
-
84892590846
-
Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system
-
Koelsche C, Sahm F, Capper D, et al. Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system. Acta Neuropathol 2013;126(6): 907-15
-
(2013)
Acta Neuropathol
, vol.126
, Issue.6
, pp. 907-915
-
-
Koelsche, C.1
Sahm, F.2
Capper, D.3
-
50
-
-
84939890243
-
Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells
-
Barszczyk M, Buczkowicz P, Castelo-Branco P, et al. Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells. Acta Neuropathol 2014;128(6):863-77
-
(2014)
Acta Neuropathol
, vol.128
, Issue.6
, pp. 863-877
-
-
Barszczyk, M.1
Buczkowicz, P.2
Castelo-Branco, P.3
-
51
-
-
84885418335
-
Predictive biomarkers in adult gliomas: The present and the future
-
Thomas L, Di Stefano AL, Ducray F. Predictive biomarkers in adult gliomas: The present and the future. Curr Opin Oncol 2013;25(6):689-94
-
(2013)
Curr Opin Oncol
, vol.25
, Issue.6
, pp. 689-694
-
-
Thomas, L.1
Di Stefano, A.L.2
Ducray, F.3
-
52
-
-
84873362485
-
Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: A report from EORTC study 26951
-
Erdem-Eraslan L, Gravendeel LA, de Rooi J, et al. Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: a report from EORTC study 26951. J Clin Oncol 2013; 31(3):328-36
-
(2013)
J Clin Oncol
, vol.31
, Issue.3
, pp. 328-336
-
-
Erdem-Eraslan, L.1
Gravendeel, L.A.2
De Rooi, J.3
-
53
-
-
84873338121
-
Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: Long-term results of RTOG 9402
-
Cairncross G, Wang M, Shaw E, et al. Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402. J Clin Oncol 2013; 31(3):337-43
-
(2013)
J Clin Oncol
, vol.31
, Issue.3
, pp. 337-343
-
-
Cairncross, G.1
Wang, M.2
Shaw, E.3
-
54
-
-
84873345824
-
Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: Long-term follow-up of EORTC brain tumor group study 26951
-
Van den Bent MJ, Brandes AA, Taphoorn MJB, et al. Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951. J Clin Oncol 2013;31(3):344-50
-
(2013)
J Clin Oncol
, vol.31
, Issue.3
, pp. 344-350
-
-
Van Den Bent, M.J.1
Brandes, A.A.2
Taphoorn, M.J.B.3
-
55
-
-
84899760157
-
Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH
-
Cairncross JG, Wang M, Jenkins RB, et al. Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH. J Clin Oncol 2014;32(8):783-90
-
(2014)
J Clin Oncol
, vol.32
, Issue.8
, pp. 783-790
-
-
Cairncross, J.G.1
Wang, M.2
Jenkins, R.B.3
-
56
-
-
77952557556
-
Cognition and quality of life after chemotherapy plus radiotherapy (RT) vs. RT for pure and mixed anaplastic oligodendrogliomas: Radiation therapy oncology group trial 9402
-
Wang M, Cairncross G, Shaw E, et al. Cognition and quality of life after chemotherapy plus radiotherapy (RT) vs. RT for pure and mixed anaplastic oligodendrogliomas: radiation therapy oncology group trial 9402. Int J Radiat Oncol Biol Phys 2010;77(3):662-9
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.77
, Issue.3
, pp. 662-669
-
-
Wang, M.1
Cairncross, G.2
Shaw, E.3
-
60
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352(10):987-96
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
61
-
-
34247100159
-
Radiotherapy for glioblastoma in the elderly
-
Keime-Guibert F, Chinot O, Taillandier L, et al. Radiotherapy for glioblastoma in the elderly. N Engl J Med 2007;356(15): 1527-35
-
(2007)
N Engl J Med
, vol.356
, Issue.15
, pp. 1527-1535
-
-
Keime-Guibert, F.1
Chinot, O.2
Taillandier, L.3
-
62
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008;455(7216):1061-8
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1061-1068
-
-
Genome Atlas Research Network, C.1
-
63
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010; 17(1):98-110
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
64
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan CW, Verhaak RGW, McKenna A, et al. The somatic genomic landscape of glioblastoma. Cell 2013;155(2):462-77
-
(2013)
Cell
, vol.155
, Issue.2
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.W.2
McKenna, A.3
-
65
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000; 343(19):1350-4
-
(2000)
N Engl J Med
, vol.343
, Issue.19
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
-
66
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005;352(10):997-1003
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
67
-
-
84865558322
-
Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: The Nordic randomised, phase 3 trial
-
Malmström A, Grønberg BH, Marosi C, et al. Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: The Nordic randomised, phase 3 trial. Lancet Oncol 2012;13(9): 916-26
-
(2012)
Lancet Oncol
, vol.13
, Issue.9
, pp. 916-926
-
-
Malmström, A.1
Grønberg, B.H.2
Marosi, C.3
-
68
-
-
84863091424
-
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: The NOA-08 randomised, phase 3 trial
-
Wick W, Platten M, Meisner C, et al. Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: The NOA-08 randomised, phase 3 trial. Lancet Oncol 2012;13(7):707-15
-
(2012)
Lancet Oncol
, vol.13
, Issue.7
, pp. 707-715
-
-
Wick, W.1
Platten, M.2
Meisner, C.3
-
69
-
-
80051659072
-
Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: An ANOCEF phase II trial
-
Gallego Pérez-Larraya J, Ducray F, Chinot O, et al. Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial. J Clin Oncol 2011;29(22): 3050-5
-
(2011)
J Clin Oncol
, vol.29
, Issue.22
, pp. 3050-3055
-
-
Gallego Pérez-Larraya, J.1
Ducray, F.2
Chinot, O.3
-
70
-
-
84864134056
-
Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, MethyLight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNAmethyltranferase in a series of 100 glioblastoma patients
-
Quillien V, Lavenu A, Karayan-Tapon L, et al. Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, MethyLight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNAmethyltranferase in a series of 100 glioblastoma patients. Cancer 2012; 118(17):4201-11
-
(2012)
Cancer
, vol.118
, Issue.17
, pp. 4201-4211
-
-
Quillien, V.1
Lavenu, A.2
Karayan-Tapon, L.3
-
71
-
-
84863413030
-
Prognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastoma
-
Christians A, Hartmann C, Benner A, et al. Prognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastoma. PLoS ONE 2012;7(3):e33449
-
(2012)
PLoS ONE
, vol.7
, Issue.3
, pp. e33449
-
-
Christians, A.1
Hartmann, C.2
Benner, A.3
-
72
-
-
84927788328
-
The future of antiangiogenic treatment in glioblastoma
-
Chinot OL, Reardon DA. The future of antiangiogenic treatment in glioblastoma. Curr Opin Neurol 2014;27(6):675-82
-
(2014)
Curr Opin Neurol
, vol.27
, Issue.6
, pp. 675-682
-
-
Chinot, O.L.1
Reardon, D.A.2
-
73
-
-
84863092492
-
VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: An analysis of data from the AViTA and AVOREN randomised trials
-
Lambrechts D, Claes B, Delmar P, et al. VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials. Lancet Oncol 2012;13(7):724-33
-
(2012)
Lancet Oncol
, vol.13
, Issue.7
, pp. 724-733
-
-
Lambrechts, D.1
Claes, B.2
Delmar, P.3
-
74
-
-
84860356630
-
Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth
-
Hamerlik P, Lathia JD, Rasmussen R, et al. Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth. J Exp Med 2012;209(3):507-20
-
(2012)
J Exp Med
, vol.209
, Issue.3
, pp. 507-520
-
-
Hamerlik, P.1
Lathia, J.D.2
Rasmussen, R.3
-
75
-
-
84894194756
-
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma
-
Chinot OL, Wick W, Mason W, et al. Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma. N Engl J Med 2014;370(8):709-22
-
(2014)
N Engl J Med
, vol.370
, Issue.8
, pp. 709-722
-
-
Chinot, O.L.1
Wick, W.2
Mason, W.3
-
76
-
-
84894114159
-
A randomized trial of bevacizumab for newly diagnosed glioblastoma
-
Gilbert MR, Dignam JJ, Armstrong TS, et al. A randomized trial of bevacizumab for newly diagnosed glioblastoma. N Engl J Med 2014;370(8):699-708
-
(2014)
N Engl J Med
, vol.370
, Issue.8
, pp. 699-708
-
-
Gilbert, M.R.1
Dignam, J.J.2
Armstrong, T.S.3
-
77
-
-
84904913239
-
Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): A randomised controlled phase 2 trial
-
TaalW, Oosterkamp HM, Walenkamp AM, et al. Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial. Lancet Oncol 2014; 15(9):943-53
-
(2014)
Lancet Oncol
, vol.15
, Issue.9
, pp. 943-953
-
-
Taal, W.1
Oosterkamp, H.M.2
Walenkamp, A.M.3
-
78
-
-
84911097954
-
Targeted molecular therapies against epidermal growth factor receptor: Past experiences and challenges
-
Reardon DA, Wen PY, Mellinghoff IK. Targeted molecular therapies against epidermal growth factor receptor: past experiences and challenges. Neuro Oncol 2014;16(Suppl 8):viii7-13
-
(2014)
Neuro Oncol
, vol.16
, pp. viii7-13
-
-
Reardon, D.A.1
Wen, P.Y.2
Mellinghoff, I.K.3
-
79
-
-
52949098192
-
Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors
-
Sampson JH, Akabani G, Archer GE, et al. Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors. Neuro Oncol 2008;10(3):320-9
-
(2008)
Neuro Oncol
, vol.10
, Issue.3
, pp. 320-329
-
-
Sampson, J.H.1
Akabani, G.2
Archer, G.E.3
-
82
-
-
84964315887
-
Spatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas
-
Van Thuijl HF, Scheinin I, Sie D, et al. Spatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas. Genome Biol 2014;15(9):471
-
(2014)
Genome Biol
, vol.15
, Issue.9
, pp. 471
-
-
Van Thuijl, H.F.1
Scheinin, I.2
Sie, D.3
-
83
-
-
84874598318
-
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
-
Sottoriva A, Spiteri I, Piccirillo SG, et al. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc Natl Acad Sci USA 2013; 110(10):4009-14
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.10
, pp. 4009-4014
-
-
Sottoriva, A.1
Spiteri, I.2
Piccirillo, S.G.3
-
84
-
-
84905447834
-
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing
-
Francis JM, Zhang CZ, Maire CL, et al. EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing. Cancer Discov 2014;4(8):956-71
-
(2014)
Cancer Discov
, vol.4
, Issue.8
, pp. 956-971
-
-
Francis, J.M.1
Zhang, C.Z.2
Maire, C.L.3
-
85
-
-
77956227086
-
Interobserver variation of the histopathological diagnosis in clinical trials on glioma: A clinician's perspective
-
Van den Bent MJ. Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician's perspective. Acta Neuropathol 2010;120(3):297-304
-
(2010)
Acta Neuropathol
, vol.120
, Issue.3
, pp. 297-304
-
-
Van Den Bent, M.J.1
-
86
-
-
78651082266
-
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas
-
Hartmann C, Hentschel B, Wick W, et al. Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathol 2010;120(6):707-18
-
(2010)
Acta Neuropathol
, vol.120
, Issue.6
, pp. 707-718
-
-
Hartmann, C.1
Hentschel, B.2
Wick, W.3
-
87
-
-
84939952838
-
Molecular classification of diffuse cerebral WHO grade II/III gliomas using genomeand transcriptome-wide profiling improves stratification of prognostically distinct patient groups
-
Weller M, Weber RG, Willscher E, et al. Molecular classification of diffuse cerebral WHO grade II/III gliomas using genomeand transcriptome-wide profiling improves stratification of prognostically distinct patient groups. Acta Neuropathol 2015; 129(5):679-93
-
(2015)
Acta Neuropathol
, vol.129
, Issue.5
, pp. 679-693
-
-
Weller, M.1
Weber, R.G.2
Willscher, E.3
|