Increased autophagy and apoptosis contribute to muscle atrophy in a myotonic dystrophy type 1 Drosophila model

DMM Disease Models and Mechanisms

Volumn 8, Issue 7, 2015, Pages 679-690

  Bargiela, Ariadna ^a,b   Cerro Herreros, Estefaniá ^a,b   Fernandez Costa, Juan M ^a,e   Vilchez, Juan J ^a,c,d   Llamusi, Beatriz ^b   Artero, Ruben ^a,b  

^a UNIVERSITY OF VALENCIA   (Spain)

^b Instituto Universitario IVI INCLIVA   (Spain)

^c HOSPITAL UNIVERSITARIO LA FE   (Spain)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^e Technology Park of Valencia   (Spain)

Author keywords

Apoptosis; Autophagy; CTG repeat expansion; Dystrophy; Muscle atrophy; Muscleblind

Indexed keywords

DIAP1 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MYOSIN HEAVY CHAIN; RNA; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; MUSCLEBLIND PROTEIN, DROSOPHILA; MYOTONIC DYSTROPHY PROTEIN KINASE; NUCLEAR PROTEIN; TARGET OF RAPAMYCIN KINASE; THREAD PROTEIN, DROSOPHILA;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; FLIGHT MUSCLE; FRUIT FLY MODEL; GENE OVEREXPRESSION; HEAT SHOCK; MUSCLE ATROPHY; MUSCLE TISSUE; MYOBLAST; MYOTONIC DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; REPRESSOR GENE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRINUCLEOTIDE REPEAT; ANIMAL; DISEASE MODEL; DROSOPHILA MELANOGASTER; FEMALE; GENE; GENETICS; HUMAN; MUSCULAR ATROPHY; PATHOLOGY; TRANSGENIC ANIMAL; UPREGULATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; AUTOPHAGY; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENES, INSECT; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MUSCULAR ATROPHY; MYOTONIC DYSTROPHY; MYOTONIN-PROTEIN KINASE; NUCLEAR PROTEINS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRINUCLEOTIDE REPEAT EXPANSION; UP-REGULATION;

EID: 84937951494     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.018127     Document Type: Article

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