-
1
-
-
46249125488
-
How shelterin protects mammalian telomeres
-
Palm W, de Lange T. 2008. How shelterin protects mammalian telomeres. Annu Rev Genet 42:301-334. http://dx.doi.org/10.1146/annurev .genet.41.110306.130350
-
(2008)
Annu Rev Genet
, vol.42
, pp. 301-334
-
-
Palm, W.1
de Lange, T.2
-
2
-
-
71149093724
-
How telomeres solve the end-protection problem
-
de Lange T. 2009. How telomeres solve the end-protection problem. Science 326:948-952. http://dx.doi.org/10.1126/science.1170633
-
(2009)
Science
, vol.326
, pp. 948-952
-
-
de Lange, T.1
-
3
-
-
74049111326
-
Telomeres and telomerase in cancer
-
Artandi SE, DePinho RA. 2010. Telomeres and telomerase in cancer. Carcinogenesis 31:9-18. http://dx.doi.org/10.1093/carcin/bgp268
-
(2010)
Carcinogenesis
, vol.31
, pp. 9-18
-
-
Artandi, S.E.1
DePinho, R.A.2
-
4
-
-
84872912456
-
Finding the end: recruitment of telomerase to telomeres
-
Nandakumar J, Cech TR. 2013. Finding the end: recruitment of telomerase to telomeres. Nat Rev Mol Cell Biol 14:69-82. http://dx.doi.org/10 .1038/nrm3505
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 69-82
-
-
Nandakumar, J.1
Cech, T.R.2
-
5
-
-
0030697342
-
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
-
Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR. 1997. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 3:1271-1274. http://dx.doi.org/10.1038/nm1197-1271
-
(1997)
Nat Med
, vol.3
, pp. 1271-1274
-
-
Bryan, T.M.1
Englezou, A.2
Dalla-Pozza, L.3
Dunham, M.A.4
Reddel, R.R.5
-
6
-
-
77951133257
-
Alternative lengthening of telomeres: models, mechanisms and implications
-
Cesare AJ, Reddel RR. 2010. Alternative lengthening of telomeres: models, mechanisms and implications. Nat Rev Genet 11:319-330. http://dx .doi.org/10.1038/nrg2763
-
(2010)
Nat Rev Genet
, vol.11
, pp. 319-330
-
-
Cesare, A.J.1
Reddel, R.R.2
-
7
-
-
84862514686
-
Telomerase-independent paths to immortality in predictable cancer sub-types
-
Durant ST. 2012. Telomerase-independent paths to immortality in predictable cancer sub-types. J Cancer 3:67-82. http://dx.doi.org/10.7150/jca .3965
-
(2012)
J Cancer
, vol.3
, pp. 67-82
-
-
Durant, S.T.1
-
8
-
-
80053229934
-
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes
-
Heaphy CM, Subhawong AP, Hong SM, Goggins MG, Montgomery EA, Gabrielson E, Netto GJ, Epstein JI, Lotan TL, Westra WH, Shih IM, Iacobuzio-Donahue CA, Maitra A, Li QK, Eberhart CG, Taube JM, Rakheja D, Kurman RJ, Wu TC, Roden RB, Argani P, De Marzo AM, Terracciano L, Torbenson M, Meeker AK. 2011. Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes. Am J Pathol 179:1608-1615. http://dx.doi.org/10 .1016/j.ajpath.2011.06.018
-
(2011)
Am J Pathol
, vol.179
, pp. 1608-1615
-
-
Heaphy, C.M.1
Subhawong, A.P.2
Hong, S.M.3
Goggins, M.G.4
Montgomery, E.A.5
Gabrielson, E.6
Netto, G.J.7
Epstein, J.I.8
Lotan, T.L.9
Westra, W.H.10
Shih, I.M.11
Iacobuzio-Donahue, C.A.12
Maitra, A.13
Li, Q.K.14
Eberhart, C.G.15
Taube, J.M.16
Rakheja, D.17
Kurman, R.J.18
Wu, T.C.19
Roden, R.B.20
Argani, P.21
De Marzo, A.M.22
Terracciano, L.23
Torbenson, M.24
Meeker, A.K.25
more..
-
9
-
-
19944428332
-
A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas
-
Henson JD, Hannay JA, McCarthy SW, Royds JA, Yeager TR, Robinson RA, Wharton SB, Jellinek DA, Arbuckle SM, Yoo J, Robinson BG, Learoyd DL, Stalley PD, Bonar SF, Yu D, Pollock RE, Reddel RR. 2005. A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas. Clin Cancer Res 11:217-225.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 217-225
-
-
Henson, J.D.1
Hannay, J.A.2
McCarthy, S.W.3
Royds, J.A.4
Yeager, T.R.5
Robinson, R.A.6
Wharton, S.B.7
Jellinek, D.A.8
Arbuckle, S.M.9
Yoo, J.10
Robinson, B.G.11
Learoyd, D.L.12
Stalley, P.D.13
Bonar, S.F.14
Yu, D.15
Pollock, R.E.16
Reddel, R.R.17
-
10
-
-
79960700556
-
Altered telomeres in tumors with ATRX and DAXX mutations
-
Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, Bigner DD, Oba-Shinjo SM, Marie SK, Riggins GJ, Kinzler KW, Vogelstein B, Hruban RH, Maitra A, Papadopoulos N, Meeker AK. 2011. Altered telomeres in tumors with ATRX and DAXX mutations. Science 333:425. http://dx.doi.org/10.1126/science.1207313
-
(2011)
Science
, vol.333
, pp. 425
-
-
Heaphy, C.M.1
de Wilde, R.F.2
Jiao, Y.3
Klein, A.P.4
Edil, B.H.5
Shi, C.6
Bettegowda, C.7
Rodriguez, F.J.8
Eberhart, C.G.9
Hebbar, S.10
Offerhaus, G.J.11
McLendon, R.12
Rasheed, B.A.13
He, Y.14
Yan, H.15
Bigner, D.D.16
Oba-Shinjo, S.M.17
Marie, S.K.18
Riggins, G.J.19
Kinzler, K.W.20
Vogelstein, B.21
Hruban, R.H.22
Maitra, A.23
Papadopoulos, N.24
Meeker, A.K.25
more..
-
11
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber J, Korshunov A, Liu XY, Jones DTW, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DK, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, Lindroth A, Jäger N, Rausch T, Ryzhova M, Korbel JO, Hielscher T, Hauser P, Garami M, Klekner A, Bognar L, Ebinger M, Schuhmann MU, Scheurlen W, Pekrun A, Frühwald MC, Roggendorf W, Kramm C, Dürken M, Atkinson J, Lepage P, Montpetit A, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel P, Kulozik AE, Zapatka M, Guha A, Malkin D, Felsberg J, Reifenberger G, von Deimling A, Ichimura K, Collins VP, Witt H, Milde T, Witt O, Zhang C, Castelo-Branco P, Lichter P, Faury D, Tabori U, Plass C, Majewski J, Pfister SM, Jabado N. 2012. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 482:226-231. http://dx.doi.org /10.1038/nature10833
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
Jones, D.T.W.4
Pfaff, E.5
Jacob, K.6
Sturm, D.7
Fontebasso, A.M.8
Quang, D.K.9
Tönjes, M.10
Hovestadt, V.11
Albrecht, S.12
Kool, M.13
Nantel, A.14
Konermann, C.15
Lindroth, A.16
Jäger, N.17
Rausch, T.18
Ryzhova, M.19
Korbel, J.O.20
Hielscher, T.21
Hauser, P.22
Garami, M.23
Klekner, A.24
Bognar, L.25
Ebinger, M.26
Schuhmann, M.U.27
Scheurlen, W.28
Pekrun, A.29
Frühwald, M.C.30
Roggendorf, W.31
Kramm, C.32
Dürken, M.33
Atkinson, J.34
Lepage, P.35
Montpetit, A.36
Zakrzewska, M.37
Zakrzewski, K.38
Liberski, P.P.39
Dong, Z.40
Siegel, P.41
Kulozik, A.E.42
Zapatka, M.43
Guha, A.44
Malkin, D.45
Felsberg, J.46
Reifenberger, G.47
von Deimling, A.48
Ichimura, K.49
Collins, V.P.50
Witt, H.51
Milde, T.52
Witt, O.53
Zhang, C.54
Castelo-Branco, P.55
Lichter, P.56
Faury, D.57
Tabori, U.58
Plass, C.59
Majewski, J.60
Pfister, S.M.61
Jabado, N.62
more..
-
12
-
-
80053994579
-
ATRX in chromatin assembly and genome architecture during development and disease
-
Bérubé NG. 2011. ATRX in chromatin assembly and genome architecture during development and disease. Biochem Cell Biol 89:435-444. http://dx .doi.org/10.1139/o11-038
-
(2011)
Biochem Cell Biol
, vol.89
, pp. 435-444
-
-
Bérubé, N.G.1
-
13
-
-
38749117849
-
Loss of ATRX leads to chromosome cohesion and congression defects
-
Ritchie K, Seah C, Moulin J, Isaac C, Dick F, Bérubé NG. 2008. Loss of ATRX leads to chromosome cohesion and congression defects. J Cell Biol 180:315-324. http://dx.doi.org/10.1083/jcb.200706083
-
(2008)
J Cell Biol
, vol.180
, pp. 315-324
-
-
Ritchie, K.1
Seah, C.2
Moulin, J.3
Isaac, C.4
Dick, F.5
Bérubé, N.G.6
-
14
-
-
84855984815
-
Expression of telomeres in astrocytoma WHO grade 2 to 4: TERRA level correlates with telomere length, telomerase activity, and advanced clinical grade
-
Sampl S, Pramhas S, Stern C, Preusser M, Marosi C, Holzmann K. 2012. Expression of telomeres in astrocytoma WHO grade 2 to 4: TERRA level correlates with telomere length, telomerase activity, and advanced clinical grade. Transl Oncol 5:56-65. http://dx.doi.org/10.1593/tlo.11202
-
(2012)
Transl Oncol
, vol.5
, pp. 56-65
-
-
Sampl, S.1
Pramhas, S.2
Stern, C.3
Preusser, M.4
Marosi, C.5
Holzmann, K.6
-
15
-
-
45249110498
-
A quantitative real-time PCR method for absolute telomere length
-
O'Callaghan N, Dhillon V, Thomas P, Fenech M. 2008. A quantitative real-time PCR method for absolute telomere length. Biotechniques 44:807-809. http://dx.doi.org/10.2144/000112761
-
(2008)
Biotechniques
, vol.44
, pp. 807-809
-
-
O'Callaghan, N.1
Dhillon, V.2
Thomas, P.3
Fenech, M.4
-
16
-
-
84868534644
-
A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection
-
Deng Z, Wang Z, Stong N, Plasschaert R, Moczan A, Chen HS, Hu S, Wikramasinghe P, Davuluri RV, Bartolomei MS, Riethman H, Lieberman PM. 2012. A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection. EMBO J 31:4165-4178. http://dx.doi.org/10.1038/emboj.2012.266
-
(2012)
EMBO J
, vol.31
, pp. 4165-4178
-
-
Deng, Z.1
Wang, Z.2
Stong, N.3
Plasschaert, R.4
Moczan, A.5
Chen, H.S.6
Hu, S.7
Wikramasinghe, P.8
Davuluri, R.V.9
Bartolomei, M.S.10
Riethman, H.11
Lieberman, P.M.12
-
17
-
-
66249147593
-
Association between transcriptional activity, local chromatin structure, and the efficiencies of both subpathways of nucleotide excision repair of melphalan adducts
-
Episkopou H, Kyrtopoulos SA, Sfikakis PP, Fousteri M, Dimopoulos MA, Mullenders LHF, Souliotis VL. 2009. Association between transcriptional activity, local chromatin structure, and the efficiencies of both subpathways of nucleotide excision repair of melphalan adducts. Cancer Res 69:4424-4433. http://dx.doi.org/10.1158/0008-5472.CAN-08-3489
-
(2009)
Cancer Res
, vol.69
, pp. 4424-4433
-
-
Episkopou, H.1
Kyrtopoulos, S.A.2
Sfikakis, P.P.3
Fousteri, M.4
Dimopoulos, M.A.5
Mullenders, L.H.F.6
Souliotis, V.L.7
-
18
-
-
71849088980
-
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity
-
Henson JD, Cao Y, Huschtscha LI, Chang AC, Au AYM, Pickett HA, Reddel RR. 2009. DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity. Nat Biotechnol 27:1181-1186. http://dx.doi.org/10.1038/nbt.1587
-
(2009)
Nat Biotechnol
, vol.27
, pp. 1181-1186
-
-
Henson, J.D.1
Cao, Y.2
Huschtscha, L.I.3
Chang, A.C.4
Au, A.Y.M.5
Pickett, H.A.6
Reddel, R.R.7
-
19
-
-
0033199695
-
Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body
-
Yeager T, Neumann A, Englezou A, Huschtscha L, Noble J, Reddel R. 1999. Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res 59:4175-4179.
-
(1999)
Cancer Res
, vol.59
, pp. 4175-4179
-
-
Yeager, T.1
Neumann, A.2
Englezou, A.3
Huschtscha, L.4
Noble, J.5
Reddel, R.6
-
20
-
-
84868625787
-
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
-
Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, de Wilde RF, Rodriguez FJ, Rosemberg S, Oba-Shinjo SM, Nagahashi Marie SK, Bettegowda C, Agrawal N, Lipp E, Pirozzi C, Lopez G, He Y, Friedman H, Friedman AH, Riggins GJ, Holdhoff M, Burger P, McLendon R, Bigner DD, Vogelstein B, Meeker AK, Kinzler KW, Papadopoulos N, Diaz LA, Yan H. 2012. Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget 3:709-722.
-
(2012)
Oncotarget
, vol.3
, pp. 709-722
-
-
Jiao, Y.1
Killela, P.J.2
Reitman, Z.J.3
Rasheed, A.B.4
Heaphy, C.M.5
de Wilde, R.F.6
Rodriguez, F.J.7
Rosemberg, S.8
Oba-Shinjo, S.M.9
Nagahashi Marie, S.K.10
Bettegowda, C.11
Agrawal, N.12
Lipp, E.13
Pirozzi, C.14
Lopez, G.15
He, Y.16
Friedman, H.17
Friedman, A.H.18
Riggins, G.J.19
Holdhoff, M.20
Burger, P.21
McLendon, R.22
Bigner, D.D.23
Vogelstein, B.24
Meeker, A.K.25
Kinzler, K.W.26
Papadopoulos, N.27
Diaz, L.A.28
Yan, H.29
more..
-
21
-
-
84872788316
-
Whole exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma
-
Kannan K, Inagaki A, Silber J, Gorovets D, Zhang J, Kastenhuber ER, Heguy A, Petrini JH, Chan TA, Huse JT. 2012. Whole exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma. Oncotarget 3:1194-1203.
-
(2012)
Oncotarget
, vol.3
, pp. 1194-1203
-
-
Kannan, K.1
Inagaki, A.2
Silber, J.3
Gorovets, D.4
Zhang, J.5
Kastenhuber, E.R.6
Heguy, A.7
Petrini, J.H.8
Chan, T.A.9
Huse, J.T.10
-
22
-
-
84871020024
-
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
-
Liu XY, Gerges N, Korshunov A, Sabha N, Khuong-Quang DA, Fontebasso AM, Fleming A, Hadjadj D, Schwartzentruber J, Majewski J, Dong Z, Siegel P, Albrecht S, Croul S, Jones DT, Kool M, Tonjes M, Reifenberger G, Faury D, Zadeh G, Pfister S, Jabado N. 2012. Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations. Acta Neuropathol 124:615-625. http://dx.doi.org/10.1007/s00401-012-1031-3
-
(2012)
Acta Neuropathol
, vol.124
, pp. 615-625
-
-
Liu, X.Y.1
Gerges, N.2
Korshunov, A.3
Sabha, N.4
Khuong-Quang, D.A.5
Fontebasso, A.M.6
Fleming, A.7
Hadjadj, D.8
Schwartzentruber, J.9
Majewski, J.10
Dong, Z.11
Siegel, P.12
Albrecht, S.13
Croul, S.14
Jones, D.T.15
Kool, M.16
Tonjes, M.17
Reifenberger, G.18
Faury, D.19
Zadeh, G.20
Pfister, S.21
Jabado, N.22
more..
-
23
-
-
84876294049
-
Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas
-
Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ. 2013. Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathol 23:237-243. http://dx.doi.org/10.1111/j.1750-3639 .2012.00630.x
-
(2013)
Brain Pathol
, vol.23
, pp. 237-243
-
-
Nguyen, D.N.1
Heaphy, C.M.2
de Wilde, R.F.3
Orr, B.A.4
Odia, Y.5
Eberhart, C.G.6
Meeker, A.K.7
Rodriguez, F.J.8
-
24
-
-
84869860972
-
Loss of wild-type ATRX expression in somatic cell hybrids segregates with activation of alternative lengthening of telomeres
-
Bower K, Napier CE, Cole SL, Dagg RA, Lau LMS, Duncan EM, Moy EL, Reddel RR. 2012. Loss of wild-type ATRX expression in somatic cell hybrids segregates with activation of alternative lengthening of telomeres. PLoS One 7:e50062. http://dx.doi.org/10.1371/journal.pone.0050062
-
(2012)
PLoS One
, vol.7
, pp. e50062
-
-
Bower, K.1
Napier, C.E.2
Cole, S.L.3
Dagg, R.A.4
Lau, L.M.S.5
Duncan, E.M.6
Moy, E.L.7
Reddel, R.R.8
-
25
-
-
84864619205
-
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
-
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JHJ, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, Macconaill L, Hanna M, Hahn WC, Lue NF, Reddel RR, Jiao Y, Kinzler K, Vogelstein B, Papadopoulos N, Meeker AK, ALT Starr Cancer Consortium. 2012. Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet 8:e1002772. http://dx .doi.org/10.1371/journal.pgen.1002772
-
(2012)
PLoS Genet
, vol.8
, pp. e1002772
-
-
Lovejoy, C.A.1
Li, W.2
Reisenweber, S.3
Thongthip, S.4
Bruno, J.5
de Lange, T.6
De, S.7
Petrini, J.H.J.8
Sung, P.A.9
Jasin, M.10
Rosenbluh, J.11
Zwang, Y.12
Weir, B.A.13
Hatton, C.14
Ivanova, E.15
Macconaill, L.16
Hanna, M.17
Hahn, W.C.18
Lue, N.F.19
Reddel, R.R.20
Jiao, Y.21
Kinzler, K.22
Vogelstein, B.23
Papadopoulos, N.24
Meeker, A.K.25
more..
-
26
-
-
79953013144
-
Alternative lengthening of telomeres in human glioma stem cells
-
Silvestre DC, Pineda Marti JR, Hoffschir F, Studler J-M, Mouthon M-A, Pflumio F, Junier M-P, Chneiweisse H, Boussin FD. 2011. Alternative lengthening of telomeres in human glioma stem cells. Stem Cells 29:440-451. http://dx.doi.org/10.1002/stem.600
-
(2011)
Stem Cells
, vol.29
, pp. 440-451
-
-
Silvestre, D.C.1
Pineda Marti, J.R.2
Hoffschir, F.3
Studler, J.-M.4
Mouthon, M.-A.5
Pflumio, F.6
Junier, M.-P.7
Chneiweisse, H.8
Boussin, F.D.9
-
27
-
-
84885484823
-
A glioblastoma neurosphere line with alternative lengthening of telomeres
-
Heaphy CM, Schreck KC, Raabe E, Mao XG, An P, Chu Q, Poh W, Jiao Y, Rodriguez FJ, Odia Y, Meeker AK, Eberhart CG. 2013. A glioblastoma neurosphere line with alternative lengthening of telomeres. Acta Neuropathol 126:607-608. http://dx.doi.org/10.1007/s00401-013-1174-x
-
(2013)
Acta Neuropathol
, vol.126
, pp. 607-608
-
-
Heaphy, C.M.1
Schreck, K.C.2
Raabe, E.3
Mao, X.G.4
An, P.5
Chu, Q.6
Poh, W.7
Jiao, Y.8
Rodriguez, F.J.9
Odia, Y.10
Meeker, A.K.11
Eberhart, C.G.12
-
28
-
-
84925540998
-
A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres
-
Borodovsky A, Meeker AK, Kirkness EF, Zhao Q, Eberhart CG, Gallia GL, Riggins GJ. 2015. A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres. J Neurooncol 121:479-487. http://dx.doi.org/10.1007/s11060-014-1672-2
-
(2015)
J Neurooncol
, vol.121
, pp. 479-487
-
-
Borodovsky, A.1
Meeker, A.K.2
Kirkness, E.F.3
Zhao, Q.4
Eberhart, C.G.5
Gallia, G.L.6
Riggins, G.J.7
-
29
-
-
0346056814
-
A conserved truncated isoform of the ATR-X syndrome protein lacking the SWI/SNF-homology domain
-
Garrick D, Samara V, McDowell TL, Smith AJ, Dobbie L, Higgs DR, Gibbons RJ. 2004. A conserved truncated isoform of the ATR-X syndrome protein lacking the SWI/SNF-homology domain. Gene 326:23-34. http://dx.doi.org/10.1016/j.gene.2003.10.026
-
(2004)
Gene
, vol.326
, pp. 23-34
-
-
Garrick, D.1
Samara, V.2
McDowell, T.L.3
Smith, A.J.4
Dobbie, L.5
Higgs, D.R.6
Gibbons, R.J.7
-
30
-
-
77649099092
-
Distinct factors control histone variant H3.3 localization at specific genomic regions
-
Goldberg AD, Banaszynski LA, Noh KM, Lewis PW, Elsaesser SJ, Stadler S, Dewell S, Law M, Guo X, Li X, Wen D, Chapgier A, DeKelver RC, Miller JC, Lee YL, Boydston EA, Holmes MC, Gregory PD, Greally JM, Rafii S, Yang C, Scambler PJ, Garrick D, Gibbons RJ, Higgs DR, Cristea IM, Urnov FD, Zheng D, Allis CD. 2010. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell 140:678-691. http://dx.doi.org/10.1016/j.cell.2010.01.003
-
(2010)
Cell
, vol.140
, pp. 678-691
-
-
Goldberg, A.D.1
Banaszynski, L.A.2
Noh, K.M.3
Lewis, P.W.4
Elsaesser, S.J.5
Stadler, S.6
Dewell, S.7
Law, M.8
Guo, X.9
Li, X.10
Wen, D.11
Chapgier, A.12
DeKelver, R.C.13
Miller, J.C.14
Lee, Y.L.15
Boydston, E.A.16
Holmes, M.C.17
Gregory, P.D.18
Greally, J.M.19
Rafii, S.20
Yang, C.21
Scambler, P.J.22
Garrick, D.23
Gibbons, R.J.24
Higgs, D.R.25
Cristea, I.M.26
Urnov, F.D.27
Zheng, D.28
Allis, C.D.29
more..
-
31
-
-
84866115963
-
Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1_
-
Arnoult N, Van Beneden A, Decottignies A. 2012. Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1_. Nat Struct Mol Biol 19:948-956. http://dx.doi.org/10 .1038/nsmb.2364
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 948-956
-
-
Arnoult, N.1
Van Beneden, A.2
Decottignies, A.3
-
32
-
-
84926480208
-
ATRX promotes gene expression by facilitating transcriptional elongation through guanine- rich coding regions
-
Levy MA, Kernohan KD, Jiang Y, Bérubé NG. 2015. ATRX promotes gene expression by facilitating transcriptional elongation through guanine- rich coding regions. Hum Mol Genet 24:1824-1835. http://dx.doi .org/10.1093/hmg/ddu596
-
(2015)
Hum Mol Genet
, vol.24
, pp. 1824-1835
-
-
Levy, M.A.1
Kernohan, K.D.2
Jiang, Y.3
Bérubé, N.G.4
-
33
-
-
37349043972
-
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends
-
Azzalin CM, Reichenbach P, Khoriauli L, Giulotto E, Lingner J. 2007. Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 318:798-801. http://dx.doi.org/10 .1126/science.1147182
-
(2007)
Science
, vol.318
, pp. 798-801
-
-
Azzalin, C.M.1
Reichenbach, P.2
Khoriauli, L.3
Giulotto, E.4
Lingner, J.5
-
34
-
-
68949198783
-
TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres
-
Deng Z, Norseen J, Wiedmer A, Riethman H, Lieberman PM. 2009. TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres. Mol Cell 35:403-413. http://dx.doi.org/10 .1016/j.molcel.2009.06.025
-
(2009)
Mol Cell
, vol.35
, pp. 403-413
-
-
Deng, Z.1
Norseen, J.2
Wiedmer, A.3
Riethman, H.4
Lieberman, P.M.5
-
35
-
-
84899017741
-
Alternative lengthening of telomeres is characterized by reduced compaction of telomeric chromatin
-
Episkopou H, Draskovic I, Van Beneden A, Tilman G, Mattiussi M, Gobin M, Arnoult N, Londono-Vallejo A, Decottignies A. 2014. Alternative lengthening of telomeres is characterized by reduced compaction of telomeric chromatin. Nucleic Acids Res 42:4391-4405. http://dx.doi.org /10.1093/nar/gku114
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 4391-4405
-
-
Episkopou, H.1
Draskovic, I.2
Van Beneden, A.3
Tilman, G.4
Mattiussi, M.5
Gobin, M.6
Arnoult, N.7
Londono-Vallejo, A.8
Decottignies, A.9
-
36
-
-
76249083210
-
ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain
-
Kernohan KD, Jiang Y, Tremblay DC, Bonivissuto AC, Eubanks JH, Mann MRW, Bérubé NG. 2010. ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain. Dev Cell 18:191-202. http://dx.doi.org/10.1016/j.devcel.2009.12 .017
-
(2010)
Dev Cell
, vol.18
, pp. 191-202
-
-
Kernohan, K.D.1
Jiang, Y.2
Tremblay, D.C.3
Bonivissuto, A.C.4
Eubanks, J.H.5
Mann, M.R.W.6
Bérubé, N.G.7
-
37
-
-
77958494782
-
ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a sizedependent manner
-
Law MJ, Lower KM, Voon HP, Hughes JR, Garrick D, Viprakasit V, Mitson M, De Gobbi M, Marra M, Morris A, Abbott A, Wilder SP, Taylor S, Santos GM, Cross J, Ayyub H, Jones S, Ragoussis J, Rhodes D, Dunham I, Higgs DR, Gibbons RJ. 2010. ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a sizedependent manner. Cell 143:367-378. http://dx.doi.org/10.1016/j.cell .2010.09.023
-
(2010)
Cell
, vol.143
, pp. 367-378
-
-
Law, M.J.1
Lower, K.M.2
Voon, H.P.3
Hughes, J.R.4
Garrick, D.5
Viprakasit, V.6
Mitson, M.7
De Gobbi, M.8
Marra, M.9
Morris, A.10
Abbott, A.11
Wilder, S.P.12
Taylor, S.13
Santos, G.M.14
Cross, J.15
Ayyub, H.16
Jones, S.17
Ragoussis, J.18
Rhodes, D.19
Dunham, I.20
Higgs, D.R.21
Gibbons, R.J.22
more..
-
38
-
-
77649262618
-
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
-
Wong LH, McGhie JD, Sim M, Anderson MA, Ahn S, Hannan RD, George AJ, Morgan KA, Mann JR, Choo KHA. 2010. ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells. Genome Res 20:351-360. http://dx.doi.org/10.1101/gr .101477.109
-
(2010)
Genome Res
, vol.20
, pp. 351-360
-
-
Wong, L.H.1
McGhie, J.D.2
Sim, M.3
Anderson, M.A.4
Ahn, S.5
Hannan, R.D.6
George, A.J.7
Morgan, K.A.8
Mann, J.R.9
Choo, K.H.A.10
-
39
-
-
84877115679
-
Atrx deficiency induces telomere dysfunction, en- docrine defects, and reduced life span
-
Watson LA, Solomon LA, Li JR, Jiang Y, Edwards M, Shin-ya K, Beier F, Bérubé NG. 2013. Atrx deficiency induces telomere dysfunction, en- docrine defects, and reduced life span. J Clin Invest 123:2049-2063. http://dx.doi.org/10.1172/JCI65634
-
(2013)
J Clin Invest
, vol.123
, pp. 2049-2063
-
-
Watson, L.A.1
Solomon, L.A.2
Li, J.R.3
Jiang, Y.4
Edwards, M.5
Shin-ya, K.6
Beier, F.7
Bérubé, N.G.8
-
40
-
-
84877283370
-
PMLbodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells
-
Chang FTM, McGhie JD, Chan FL, Tang MC, Anderson MA, Mann JR, Choo KHA, Wong LH. 2013.PMLbodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells. Nucleic Acids Res 41:4447-4458. http://dx.doi.org/10.1093/nar/gkt114.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 4447-4458
-
-
Chang, F.T.M.1
McGhie, J.D.2
Chan, F.L.3
Tang, M.C.4
Anderson, M.A.5
Mann, J.R.6
Choo, K.H.A.7
Wong, L.H.8
-
41
-
-
73249117060
-
CpG-island promoters drive transcription of human telomeres
-
Nergadze SG, Farnung BO, Wischnewski H, Khoriauli L, Vitelli V, Chawla R, Giulotto E, Azzalin CM. 2009. CpG-island promoters drive transcription of human telomeres. RNA 15:2186-2194. http://dx.doi.org /10.1261/rna.1748309
-
(2009)
RNA
, vol.15
, pp. 2186-2194
-
-
Nergadze, S.G.1
Farnung, B.O.2
Wischnewski, H.3
Khoriauli, L.4
Vitelli, V.5
Chawla, R.6
Giulotto, E.7
Azzalin, C.M.8
-
42
-
-
84922480767
-
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors
-
Flynn RL, Cox KE, Jeitany M, Wakimoto H, Bryll AR, Ganem NJ, Bersani F, Pineda JR, Suvà ML, Benes CH, Haber DA, Boussin FD, Zou L. 2015. Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors. Science 347:273-277. http://dx.doi.org/10 .1126/science.1257216
-
(2015)
Science
, vol.347
, pp. 273-277
-
-
Flynn, R.L.1
Cox, K.E.2
Jeitany, M.3
Wakimoto, H.4
Bryll, A.R.5
Ganem, N.J.6
Bersani, F.7
Pineda, J.R.8
Suvà, M.L.9
Benes, C.H.10
Haber, D.A.11
Boussin, F.D.12
Zou, L.13
-
43
-
-
79953033701
-
TERRA and hnRNPA1 orchestrate an RPAto-POT1 switch on telomeric single-stranded DNA
-
Flynn RL, Centore RC, O'Sullivan RJ, Rai R, Tse A, Songyang Z, Chang S, Karlseder J, Zou L. 2011. TERRA and hnRNPA1 orchestrate an RPAto-POT1 switch on telomeric single-stranded DNA. Nature 471:532-536. http://dx.doi.org/10.1038/nature09772
-
(2011)
Nature
, vol.471
, pp. 532-536
-
-
Flynn, R.L.1
Centore, R.C.2
O'Sullivan, R.J.3
Rai, R.4
Tse, A.5
Songyang, Z.6
Chang, S.7
Karlseder, J.8
Zou, L.9
-
44
-
-
84921969781
-
NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination
-
Conomos D, Reddel RR, Pickett HA. 2014. NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination. Nat Struct Mol Biol 21:760-770. http://dx.doi.org/10.1038/nsmb.2877
-
(2014)
Nat Struct Mol Biol
, vol.21
, pp. 760-770
-
-
Conomos, D.1
Reddel, R.R.2
Pickett, H.A.3
-
45
-
-
32344444083
-
Telomere dynamics in genome stability
-
Bhattacharyya MK, Lustig AJ. 2006. Telomere dynamics in genome stability. Trends Biochem Sci 31:114-122. http://dx.doi.org/10.1016/j.tibs .2005.12.001
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 114-122
-
-
Bhattacharyya, M.K.1
Lustig, A.J.2
-
46
-
-
84880725971
-
Alternative lengthening of telomeres: remodeling the telomere architecture
-
Conomos D, Pickett HA, Reddel RR. 2013. Alternative lengthening of telomeres: remodeling the telomere architecture. Front Oncol 3:27. http://dx.doi.org/10.3389/fonc.2013.00027
-
(2013)
Front Oncol
, vol.3
, pp. 27
-
-
Conomos, D.1
Pickett, H.A.2
Reddel, R.R.3
-
47
-
-
0029827343
-
ATRX encodes a novel member of the SNF2 family of proteins:mutations point to a common mechanism underlying the ATR-X syndrome
-
Picketts DJ, Higgs DR, Bachoo S, Blake DJ, Quarrell OW, Gibbons RJ. 1996. ATRX encodes a novel member of the SNF2 family of proteins:mutations point to a common mechanism underlying the ATR-X syndrome. Hum Mol Genet 5:1899-1907. http://dx.doi.org/10.1093/hmg/5.12.1899
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1899-1907
-
-
Picketts, D.J.1
Higgs, D.R.2
Bachoo, S.3
Blake, D.J.4
Quarrell, O.W.5
Gibbons, R.J.6
-
48
-
-
0032959506
-
RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase
-
Le S, Moore JK, Haber JE, Greider CW. 1999. RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics 152:143-152.
-
(1999)
Genetics
, vol.152
, pp. 143-152
-
-
Le, S.1
Moore, J.K.2
Haber, J.E.3
Greider, C.W.4
-
49
-
-
0033513079
-
Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae
-
Teng SC, Zakian VA. 1999. Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol Cell Biol 19:8083-8093.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 8083-8093
-
-
Teng, S.C.1
Zakian, V.A.2
-
50
-
-
0037426088
-
Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme
-
Hakin-Smith V, Jellinek DA, Levy D, Carroll T, Teo M, Timperley WR, McKay MJ, Reddel RR, Royds JA. 2003. Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme. Lancet 361:836-838. http://dx.doi.org/10.1016/S0140-6736(03)12681-5
-
(2003)
Lancet
, vol.361
, pp. 836-838
-
-
Hakin-Smith, V.1
Jellinek, D.A.2
Levy, D.3
Carroll, T.4
Teo, M.5
Timperley, W.R.6
McKay, M.J.7
Reddel, R.R.8
Royds, J.A.9
-
51
-
-
0344837710
-
Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma
-
Ulaner GA, Huang HY, Otero J, Zhao Z, Ben-Porat L, Satagopan JM, Gorlick R, Meyers P, Healey JH, Huvos AG, Hoffman AR, Ladanyi M. 2003. Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma. Cancer Res 63:1759-1763.
-
(2003)
Cancer Res
, vol.63
, pp. 1759-1763
-
-
Ulaner, G.A.1
Huang, H.Y.2
Otero, J.3
Zhao, Z.4
Ben-Porat, L.5
Satagopan, J.M.6
Gorlick, R.7
Meyers, P.8
Healey, J.H.9
Huvos, A.G.10
Hoffman, A.R.11
Ladanyi, M.12
-
52
-
-
84893757512
-
Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1
-
O'Sullivan RJ, Arnoult N, Lackner DH, Oganesian L, Haggblom C, Corpet A, Almouzni G, Karlseder J. 2014. Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1. Nat Struct Mol Biol 21:167-174. http://dx.doi.org/10.1038/nsmb.2754
-
(2014)
Nat Struct Mol Biol
, vol.21
, pp. 167-174
-
-
O'Sullivan, R.J.1
Arnoult, N.2
Lackner, D.H.3
Oganesian, L.4
Haggblom, C.5
Corpet, A.6
Almouzni, G.7
Karlseder, J.8
|