Airway epithelial cell integrity protects from cytotoxicity of pseudomonas aeruginosa quorum-sensing signals

American Journal of Respiratory Cell and Molecular Biology

Volumn 53, Issue 2, 2015, Pages 265-275

  Losa, Davide ^a   Kohler, Thilo ^b   Bacchetta, Marc ^a   Saab, Joanna Bou ^a   Frieden, Maud ^a   Van Delden, Christian ^b   Chanson, Marc ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b Department of Microbiology and Molecular Genetics ^*  (Switzerland)

Author keywords

Calcium; Cystic fibrosis; Gap junctions; Pseudomonas aeruginosa; Quorum sensing

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ARYLDIALKYLPHOSPHATASE 1; ARYLDIALKYLPHOSPHATASE 2; CALCIUM; LACTONE DERIVATIVE; MICROBIAL PRODUCTS NOT CLASSIFIED ELSEWHERE; N 3 OXO DODECANOYL LEVO HOMOSERINE LACTONE; PROTEIN TYROSINE KINASE; RHO KINASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR; ARYLDIALKYLPHOSPHATASE; HOMOSERINE; LACTONE; PON2 PROTEIN, HUMAN; PSEUDOMONAS AERUGINOSA AUTOINDUCER;

AIRWAY EPITHELIAL CELL; ARTICLE; BACTERIAL CELL; BACTERIAL COLONIZATION; BACTERIAL VIRULENCE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL COMMUNICATION; CELL DENSITY; CELL POLARITY; CELL PROTECTION; CHEMICAL INTERACTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; EPITHELIUM CELL; GAP JUNCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MULTICENTER STUDY (TOPIC); NONHUMAN; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; TRACHEAL ASPIRATION PROCEDURE; ANALOGS AND DERIVATIVES; CELL LINE; HOST PATHOGEN INTERACTION; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; PSEUDOMONAS INFECTION; RESPIRATORY TRACT MUCOSA;

BACTERIA (MICROORGANISMS); MAMMALIA; PSEUDOMONAS AERUGINOSA;

ARYLDIALKYLPHOSPHATASE; CALCIUM SIGNALING; CELL COMMUNICATION; CELL LINE; EPITHELIAL CELLS; GAP JUNCTIONS; HOMOSERINE; HOST-PATHOGEN INTERACTIONS; HUMANS; LACTONES; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; QUORUM SENSING; RESPIRATORY MUCOSA;

EID: 84937736412     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2014-0405OC     Document Type: Article

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