Cx26 regulates proliferation of repairing basal airway epithelial cells

International Journal of Biochemistry and Cell Biology

Volumn 52, Issue , 2014, Pages 152-160

  Crespin, S ^a   Bacchetta, M ^a   Bou Saab, J ^a   Tantilipikorn, P ^b   Bellec, J ^c   Dudez, T ^a   Nguyen, T H ^c   Kwak, B R ^d   Lacroix, J S ^a   Huang, S ^e   Wiszniewski, L ^e   Chanson, M ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b MAHIDOL UNIVERSITY   (Thailand)

^c NANTES UNIVERSITY HOSPITAL   (France)

^d UNIVERSITY OF GENEVA   (Switzerland)

^e Epithelix   (Switzerland)

Author keywords

Cx26; Cystic fibrosis; Gap junctions; Mucilair; Proliferation; Repair

Indexed keywords

CONNEXIN 26; KI 67 ANTIGEN; KRUPPEL LIKE FACTOR 4; LENTIVIRUS VECTOR; MESSENGER RNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; GAP JUNCTION PROTEIN; KRUPPEL LIKE FACTOR;

AIRWAY; ARTICLE; BASAL CELL; CELL DIFFERENTIATION; CELL POPULATION; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; EPITHELIUM CELL; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMORTALIZED CELL LINE; LABELING INDEX; PROTEIN EXPRESSION; WOUND; WOUND CLOSURE; BRONCHUS; CELL CULTURE; CYSTIC FIBROSIS; METABOLISM; PATHOLOGY; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA;

BRONCHI; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CONNEXINS; CYSTIC FIBROSIS; EPITHELIAL CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; RESPIRATORY MUCOSA;

EID: 84901634896     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.02.010     Document Type: Article

References (36)

1. M.F. Beers, and E.E. Morrissey The three R's of lung health and disease: repair, remodelling, and regeneration J Clin Invest 121 2011 2065 2073
2. D.W. Borthwick, M. Shahbazian, Q.T. Krantz, J.R. Dorin, and S.H. Randell Evidence for stem-cell niches in the tracheal epithelium Am J Respir Cell Mol Biol 24 2001 662 670 (Pubitemid 32550587)
3. J.L. Carson, W. Reed, B.M. Moats-Staats, L.E. Brighton, T.M. Gambling, and S.C. Hu et al. Connexin26 expression in human and ferret airways and lung during development Am J Respir Cell Mol Biol 18 1998 111 119 (Pubitemid 128355353)
4. A. Chandrasekhar, E.A. Kalmykov, S.R. Polusani, S.A. Mathis, S.N. Zucker, and B.J. Nicholson Intercellular redistribution of cAMP underlies selective suppression of cancer cell growth by Connexin26 PLoS ONE 8 2013 e82335
5. M. Chanson, and M. Koval Connexins in lung function and inflammation E. Oviedo-Orta, B.R. Kwak, Connexin Cell Communication Channels: Roles in the Immune System & Immunopathology 2013 WH Evans-CRC Press 137 156
6. R. Choudhry, J.D. Pitts, and M.B. Hodgins Changing patterns of gap junctional intercellular communication and connexin distribution in mouse epidermis and hair follicles during embryonic development Dev Dyn 210 1997 417 430 (Pubitemid 27516668)
7. C.E. Cowan, E.E. Kohler, T.A. Dugan, M.K. Mirza, A.B. Malik, and K.K. Wary Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier function Circ Res 2010 959 966 107
8. A.R. Djalilian, D. McGaughey, S. Patel, E.Y. Seo, C. Yang, and J. Cheng et al. Connexin26 regulates epidermal barrier and wound remodelling and promotes psoriasiform response J Clin Invest 116 2006 1243 1253
9. M.L. Fulcher, S.E. Gabriel, J.C. Olsen, J.R. Tatreau, M. Gentzsch, and E. Livanos et al. Novel human bronchial epithelial cell lines for cystic fibrosis research Am J Physiol Lung Cell Mol Physiol 296 2009 L82 L91
10. +-ATPase inhibitor ouabain in human airway epithelial cell line Calu-3 Exp Cell Res 312 2006 3847 3856 (Pubitemid 44633885)
11. J.A. Goliger, and D.L. Paul Expression of gap junction proteins Cx36, Cx31. 1, Cx37 and Cx43 in developing and mature rat epidermis Dev Dyn 200 1994 1 13 (Pubitemid 24178283)
12. M. Ghosh, H.M. Brechbuhl, R.W. Smith, B. Li, D.A. Hicks, and T. Titchner et al. Context-dependent differentiation of multipotential keratin14-expressing tracheal basal cells Am J Respir Cell Mol Biol 45 2010 403 410
13. T.-L. Hackett, F. Shaheen, A. Johnson, S. Wadsworth, D.V. Pechkovsky, and D.B. Jacoby et al. Characterization of side population cells from human airway epithelium Stem cCells 26 2008 2576 2585
14. R. Hajj, P. Lesimple, B. Nawrocki-Raby, P. Birembaut, E. Puchelle, and C. Coraux Human airway surface epithelial regeneration is delayed and abnormal in cystic fibrosis J Pathol 211 2007 340 350 (Pubitemid 46172710)
15. K.U. Hong, S.D. Reynolds, S. Watkins, E. Fuchs, and B.R. Stripp In vivo differentiation potential of tracheal basal cells evidence for multipotent and unipotent subpopulations Am J Physiol Cell Mol Physiol 286 2004 L643 L649
16. E. Kardami, X. Danga, D.A. Iacobas, B.E. Nickel, M. Jeyaraman, and W. Srisakuldee et al. The role of connexins in controlling cell growth and gene expression Prog Biophys Mol Biol 94 2007 245 264 (Pubitemid 46782981)
17. P.A. Kumar, Y. Hu, Y. Yamamoto, N.B. Hoe, T.S. Wei, and D. Mu et al. Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection Cell 147 2011 525 538
18. D.W. Laird The gap junction proteome and its relationship to disease Trends Cell Biol 20 2010 92 101
19. P.K. Lim, S.A. Bliss, S.A. Patel, M. Taborga, M.A. Dave, and L.A. Gregory et al. Gap junction-mediated import of microRNA from bone marrow stromal cells can eleicit cell cycle quiescence in breast cancer cells Cancer Res 71 2011 1550 1560
20. B.B. McConnell, and V.W. Yang Mammalian Krüppel-like factors in health and diseases Physiol Rev 90 2010 1337 1381
21. J.L. McQualter, and I. Bertoncello Concise review deconstructing the lung to reveal its regenerative potential stem cells Stem Cells 2012 10.1002/stem.1055
22. A. Nursat, J.A. Chen, C.S. Foley, T.W. Liang, J. Tom, and M. Cromwell et al. The coiled-coil domain of occludin cana ct to organize structural and functional elements of the epithelial tight junction J Biol Chem 275 2000 29816 29822 (Pubitemid 32043866)
23. S.H. Randell Airway epithelial stem cells and the pathophysiology of chronic obstructive pulmonary disease Proc Am Thorac Soc 3 2006 718 725 (Pubitemid 44788231)
24. J.R. Rock, X. Gao, Y. Xue, S.H. Randell, Y.Y. Kong, and B.L. Hogan Notch-dependent differentiation of adult airway basal stem cells Cell Stem Cell 8 2011 639 648
25. J.R. Rock, M.W. Onaitis, E.L. Rawlins, Y. Lu, C.P. Clark, and Y. Xue et al. Basal cells as stem cells of the mouse trachea and human airway epithelium Proc Natl Acad Sci U S A 106 2009 12771 12775
26. J.-A. Segre, C. Bauer, and E. Fuchs Klf4 is a transcription factor required for establishing the barrier function of the skin Nat Genet 22 1999 356 360 (Pubitemid 29369526)
27. K.R. Schiller, P.J. Maniak, and S.M. O'Grady Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair Am J Physiol Cell Physiol 299 2010 C912 C921
28. V.H. Teixeira, P. Nadarajan, T.A. Graham, V.H. Teixeira, P. Nadarajan, and T.A. Graham et al. Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors eLife 2 2013 e00966
29. N.T. Trinh, O. Bardou, A. Privé, E. Maillé, D. Adam, and S. Lingée et al. Improvement of defective cystic fibrosis airway epithelial wound repair after CFTR rescue Eur Respir J 40 2012 1390 1400
30. M. Vinken, E. Decrock, E. De Vuyst, R. Ponsaerts, C. D'hondt, and G. Bultynck et al. Connexins: sensors and regulators of cell cycling Biochim Biophys Acta 1815 2011 13 25
31. J.A. Voynow, B.M. Fischer, B.C. Roberts, and A.D. Proia Basal-like cells constitute the proliferating cell population in cystic fibrosis airways Am J Respir Crit Care Med 172 2005 1013 1018 (Pubitemid 41476539)
32. X. Wang, A. Ramurez, and I. Budunova Overexpression of Connexin26 in the basal keratinocytes reduces sensitivity to tumor promoter TPA Exp Dermatol. 19 2010 633 640
33. M.A. Wani, S.E. Wert, and J.B. Lingrel Lung Kruppel-like factor, a zinc finger transcription factor, is essential for normal lung development J Biol Chem 274 1999 21180 21185
34. C. Wansleeben, C.E. Barkauskas, J.R. Rock, and B.L.M. Hogan Stem Cells of the adult lung: their development and role in homeostasis, regeneration and disease WIREs Dev Biol 2 2013 131 148
35. L. Wiszniewski, L. Jornot, T. Dudez, A. Pagano, T. Rochat, and J.S. Lacroix et al. Long-term cultures of polarized airway epithelial cells from CF patients Am J Respir Cell Mol Biol 34 2006 39 48 (Pubitemid 43042855)
36. L. Wiszniewski, J. Sanz, I. Scerri, E. Gasparotto, T. Dudet, and J.S. Lacroix et al. Functional expression of connexin30 and connexin31 in the polarized human airway epithelium Differentiation 75 2007 382 392 (Pubitemid 46802160)