Pseudomonas aeruginosa autoinducer modulates host cell responses through calcium signalling

Cellular Microbiology

Volumn 8, Issue 10, 2006, Pages 1601-1610

  Shiner, E K ^a,c   Terentyev, D ^d   Bryan, A ^a   Sennoune, S ^a,c   Martinez zaguilan, R ^a,c   Li, G ^a   Gyorke, S ^d   Williams, S C ^a,c   Rumbaugh, Kendra P ^a,b  

^a TEXAS TECH UNIVERSITY   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c UMC   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; INOSITOL TRISPHOSPHATE; LACTONE DERIVATIVE; PHOSPHOLIPASE C;

ANIMAL CELL; APOPTOSIS; ARTICLE; BACTERIAL VIRULENCE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; FIBROBLAST; HOST CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; INCUBATION TIME; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SIGNAL TRANSDUCTION; UPREGULATION; VASCULAR ENDOTHELIUM;

4-BUTYROLACTONE; ANIMALS; APOPTOSIS; CALCIUM SIGNALING; CYTOSOL; ENDOPLASMIC RETICULUM; ENDOTHELIAL CELLS; FIBROBLASTS; FLOW CYTOMETRY; HOMOSERINE; HUMANS; INFLAMMATION; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MICE; NIH 3T3 CELLS; PSEUDOMONAS AERUGINOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VIRULENCE FACTORS;

MAMMALIA; MURINAE; PSEUDOMONAS AERUGINOSA;

EID: 33748476988     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2006.00734.x     Document Type: Article

References (28)

1. Charlton, T.S., de Nys, R., Netting, A., Kumar, N., Hentzer, M., Givskov, M., and Kjelleberg, S. (2000) A novel and sensitive method for the quantification of N -3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: Application to a model bacterial biofilm. Environ Microbiol 2: 530-541.
2. Chhabra, S.R., Harty, C., Hooi, D.S., Daykin, M., Williams, P., Telford, G., et al. (2003) Synthetic analogues of the bacterial signal (quorum sensing) molecule N -(3-oxododecanoyl)- l -homoserine lactone as immune modulators. J Med Chem 46: 97-104.
3. Clapham, D.E. (1995) Calcium signaling. Cell 80: 259-268.
4. Erickson, D.L., Endersby, R., Kirkham, A., Stuber, K., Vollman, D.D., Rabin, H.R., et al. (2002) Pseudomonas aeruginosa quorum-sensing systems may control virulence factor expression in the lungs of patients with cystic fibrosis. Infect Immun 70: 1783-1790.
5. Ferri, K.F., and Kroemer, G. (2001) Organelle-specific initiation of cell death pathways. Nat Cell Biol 3: E255-E263.
6. Galione, A., and Churchill, G.C. (2002) Interactions between calcium release pathways: Multiple messengers and multiple stores. Cell Calcium 32: 343-354.
7. Gardiner, S.M., Chhabra, S.R., Harty, C., Williams, P., Pritchard, D.I., Bycroft, B.W., and Bennett, T. (2001) Haemodynamic effects of the bacterial quorum sensing signal molecule, N-(3-oxododecanoyl)-l-homoserine lactone, in conscious, normal and endotoxaemic rats. Br J Pharmacol 133: 1047-1054.
8. Haynes, A., III, Ruda, F., Oliver, J., Hamood, A.N., Griswold, J.A., Park, P.W. and Rumbaugh, K.P. (2005) Syndecan 1 shedding contributes to Pseudomonas aeruginosa sepsis. Infect Immun 73: 7914-7921.
9. Heist, E.K., and Schulman, H. (1998) The role of Ca2+/ calmodulin-dependent protein kinases within the nucleus. Cell Calcium 23: 103-114.
10. Lawrence, R.N., Dunn, W.R., Bycroft, B., Camara, M., Chhabra, S.R., Williams, P., and Wilson, V.G. (1999) The Pseudomonas aeruginosa quorum-sensing signal molecule, N-(3-oxododecanoyl)-l-homoserine lactone, inhibits porcine arterial smooth muscle contraction. Br J Pharmacol 128: 845-848.
11. Lazdunski, A.M., Ventre, I., and Sturgis, J.N. (2004) Regulatory circuits and communication in Gram-negative bacteria. Nat Rev Microbiol 2: 581-592.
12. Lee, Y.H., Kim, S.Y., Kim, J.R., Yoh, K.T., Baek, S.H., Kim, M.J., et al. (2000) Overexpression of phospholipase Cbeta-1 protects NIH3T3 cells from oxidative stress-induced cell death. Life Sci 67: 827-837.
13. Li, L., Hooi, D., Chhabra, S.R., Pritchard, D., and Shaw, P.E. (2004) Bacterial N -acylhomoserine lactone-induced apoptosis in breast carcinoma cells correlated with down-modulation of STAT3. Oncogene 23: 4894-4902.
14. Lodish, H., Berk, A., Zipursky, S., Matsudaira, P., Baltimore, D., and Darnell, J. (2000) Molecular Cell Biology. New York: W.H. Freeman and Company.
15. Orrenius, S., Zhivotovsky, B., and Nicotera, P. (2003) Regulation of cell death: The calcium-apoptosis link. Nat Rev Mol Cell Biol 4: 552-565.
16. Parsek, M.R., and Greenberg, E.P. (2000) Acyl-homoserine lactone quorum sensing in Gram-negative bacteria: A signaling mechanism involved in associations with higher organisms. Proc Natl Acad Sci USA 97: 8789-8793.
17. Rumbaugh, K.P., Griswold, J.A., and Hamood, A.N. (2000) The role of quorum sensing in the in vivo virulence of Pseudomonas aeruginosa. Microbes Infect 2: 1721-1731.
18. Shiner, E.K., Reddy, S., Timmons, C., Li, G., Williams, S.C., and Rumbaugh, K.P. (2004) Construction of a bacterial autoinducer detection system in mammalian cells. Biol Proced Online 6: 268-276.
19. Shiner, E.K., Rumbaugh, K.P., and Williams, S.C. (2005) Interkingdom signaling: Deciphering the language of acyl homoserine lactones. FEMS Microbiol Rev 29: 935-947.
20. Smith, R.S., Fedyk, E.R., Springer, T.A., Mukaida, N., Iglewski, B.H., and Phipps, R.P. (2001) IL-8 production in human lung fibroblasts and epithelial cells activated by the Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone is transcriptionally regulated by NF-kappa B and activator protein-2. J Immunol 167: 366-374.
21. Smith, R.S., Kelly, R., Iglewski, B.H., and Phipps, R.P. (2002a) The Pseudomonas autoinducer N -(3-oxododecanoyl) homoserine lactone induces cyclooxygenase-2 and prostaglandin E2 production in human lung fibroblasts: Implications for inflammation. J Immunol 169: 2636-2642.
22. Smith, R.S., Harris, S.G., Phipps, R., and Iglewski, B. (2002b) The Pseudomonas aeruginosa quorum-sensing molecule N -(3-oxododecanoyl) homoserine lactone contributes to virulence and induces inflammation in vivo. J Bacteriol 184: 1132-1139.
23. Sugano, M., Tsuchida, K., and Makino, N. (2002) Nifedipine prevents apoptosis of endothelial cells induced by oxidized low-density lipoproteins. J Cardiovasc Pharmacol 40: 146-152.
24. Tateda, K., Ishii, Y., Horikawa, M., Matsumoto, T., Miyairi, S., Pechere, J.C., et al. (2003) The Pseudomonas aeruginosa autoinducer N -3-oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils. Infect Immun 71: 5785-5793.
25. Telford, G., Wheeler, D., Williams, P., Tomkins, P.T., Appleby, P., Sewell, H., et al. (1998) The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-l-homoserine lactone has immunomodulatory activity. Infect Immun 66: 36-42.
26. Vannini, A., Volpari, C., Gargioli, C., Muraglia, E., Cortese, R., De Francesco, R., et al. (2002) The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA. EMBO J 21: 4393-4401.
27. Vicencio, J.M., Ibarra, C., Estrada, M., Chiong, M., Soto, D., Parra, V., et al. (2005) Testosterone induces an intracellular calcium increase by a non-genomic mechanism in cultured rat cardiac myocytes. Endocrinology 147: 1386-1395.
28. Williams, S.C., Patterson, E.K., Carty, N.L., Griswold, J.A., Hamood, A.N., and Rumbaugh, K.P. (2004) Pseudomonas aeruginosa autoinducer enters and functions in mammalian cells. J Bacteriol 186: 2281-2287.