-
1
-
-
84903701434
-
The individual and socioeconomic impact of osteoarthritis
-
D. J. Hunter, D. Schofield, E. Callander, The individual and socioeconomic impact of osteoarthritis. Nat. Rev. Rheumatol. 10, 437-441 (2014).
-
(2014)
Nat. Rev. Rheumatol.
, vol.10
, pp. 437-441
-
-
Hunter, D.J.1
Schofield, D.2
Callander, E.3
-
2
-
-
31044436046
-
Projections of US prevalence of arthritis and associated activity limitations
-
J. M. Hootman, C. G. Helmick, Projections of US prevalence of arthritis and associated activity limitations. Arthritis Rheum. 54, 226-229 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 226-229
-
-
Hootman, J.M.1
Helmick, C.G.2
-
3
-
-
73449123799
-
The economic burden of osteoarthritis
-
R. Bitton, The economic burden of osteoarthritis. Am. J. Manag. Care 15, S230-S235 (2009).
-
(2009)
Am. J. Manag. Care
, vol.15
, pp. S230-S235
-
-
Bitton, R.1
-
4
-
-
73249153284
-
Insurer and out-of-pocket costs of osteoarthritis in the US: Evidence from national survey data
-
H. Kotlarz, C. L. Gunnarsson, H. Fang, J. A. Rizzo, Insurer and out-of-pocket costs of osteoarthritis in the US: Evidence from national survey data. Arthritis Rheum. 60, 3546-3553 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3546-3553
-
-
Kotlarz, H.1
Gunnarsson, C.L.2
Fang, H.3
Rizzo, J.A.4
-
5
-
-
84856620553
-
Etiology of osteoarthritis: Genetics and synovial joint development
-
L. J. Sandell, Etiology of osteoarthritis: Genetics and synovial joint development. Nat. Rev. Rheumatol. 8, 77-89 (2012).
-
(2012)
Nat. Rev. Rheumatol.
, vol.8
, pp. 77-89
-
-
Sandell, L.J.1
-
6
-
-
55249086064
-
New insights into osteoarthritis: Early developmental features of an ageing-related disease
-
S. D. Bos, P. E. Slagboom, I. Meulenbelt, New insights into osteoarthritis: Early developmental features of an ageing-related disease. Curr. Opin. Rheumatol. 20, 553-559 (2008).
-
(2008)
Curr. Opin. Rheumatol.
, vol.20
, pp. 553-559
-
-
Bos, S.D.1
Slagboom, P.E.2
Meulenbelt, I.3
-
8
-
-
78650982530
-
The role of the cartilage matrix in osteoarthritis
-
D. Heinegard, T. Saxne, The role of the cartilage matrix in osteoarthritis. Nat. Rev. Rheumatol. 7, 50-56 (2011).
-
(2011)
Nat. Rev. Rheumatol.
, vol.7
, pp. 50-56
-
-
Heinegard, D.1
Saxne, T.2
-
9
-
-
84881541949
-
A current review of molecular mechanisms regarding osteoarthritis and pain
-
A. S. Lee, M. B. Ellman, D. Yan, J. S. Kroin, B. J. Cole, A. J. van Wijnen, H. J. Im, A current review of molecular mechanisms regarding osteoarthritis and pain. Gene 527, 440-447 (2013).
-
(2013)
Gene
, vol.527
, pp. 440-447
-
-
Lee, A.S.1
Ellman, M.B.2
Yan, D.3
Kroin, J.S.4
Cole, B.J.5
Van Wijnen, A.J.6
Im, H.J.7
-
10
-
-
83755182740
-
Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis
-
M. Wang, J. Shen, H. Jin, H. J. Im, J. Sandy, D. Chen, Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis. Ann. N. Y. Acad. Sci. 1240, 61-69 (2011).
-
(2011)
Ann. N. Y. Acad. Sci.
, vol.1240
, pp. 61-69
-
-
Wang, M.1
Shen, J.2
Jin, H.3
Im, H.J.4
Sandy, J.5
Chen, D.6
-
11
-
-
78650983649
-
Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
-
M. Kapoor, J. Martel-Pelletier, D. Lajeunesse, J. P. Pelletier, H. Fahmi, Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat. Rev. Rheumatol. 7, 33-42 (2011).
-
(2011)
Nat. Rev. Rheumatol.
, vol.7
, pp. 33-42
-
-
Kapoor, M.1
Martel-Pelletier, J.2
Lajeunesse, D.3
Pelletier, J.P.4
Fahmi, H.5
-
12
-
-
57349183076
-
The interleukin 1β pathway in the pathogenesis of osteoarthritis
-
M. Daheshia, J. Q. Yao, The interleukin 1β pathway in the pathogenesis of osteoarthritis. J. Rheumatol. 35, 2306-2312 (2008).
-
(2008)
J. Rheumatol.
, vol.35
, pp. 2306-2312
-
-
Daheshia, M.1
Yao, J.Q.2
-
13
-
-
12344252610
-
Role of interleukin-1 and tumor necrosis factor α in matrix degradation of human osteoarthritic cartilage
-
M. Kobayashi, G. R. Squires, A. Mousa, M. Tanzer, D. J. Zukor, J. Antoniou, U. Feige, A. R. Poole, Role of interleukin-1 and tumor necrosis factor α in matrix degradation of human osteoarthritic cartilage. Arthritis Rheum. 52, 128-135 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 128-135
-
-
Kobayashi, M.1
Squires, G.R.2
Mousa, A.3
Tanzer, M.4
Zukor, D.J.5
Antoniou, J.6
Feige, U.7
Poole, A.R.8
-
14
-
-
84885308609
-
Insights from human genetic studies into the pathways involved in osteoarthritis
-
L. N. Reynard, J. Loughlin, Insights from human genetic studies into the pathways involved in osteoarthritis. Nat. Rev. Rheumatol. 9, 573-583 (2013).
-
(2013)
Nat. Rev. Rheumatol.
, vol.9
, pp. 573-583
-
-
Reynard, L.N.1
Loughlin, J.2
-
15
-
-
84862545919
-
Insights on biology and pathology of HIF-1α/-2α, TGFβ/BMP, Wnt/β-catenin, and NF-κB pathways in osteoarthritis
-
L. Wu, X. Huang, L. Li, H. Huang, R. Xu, W. Luyten, Insights on biology and pathology of HIF-1α/-2α, TGFβ/BMP, Wnt/β-catenin, and NF-κB pathways in osteoarthritis. Curr. Pharm. Des. 18, 3293-3312 (2012).
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 3293-3312
-
-
Wu, L.1
Huang, X.2
Li, L.3
Huang, H.4
Xu, R.5
Luyten, W.6
-
16
-
-
77951229591
-
RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
-
Y. Dong, A. M. Jesse, A. Kohn, L. M. Gunnell, T. Honjo, M. J. Zuscik, R. J. O'Keefe, M. J. Hilton, RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development. Development 137, 1461-1471 (2010).
-
(2010)
Development
, vol.137
, pp. 1461-1471
-
-
Dong, Y.1
Jesse, A.M.2
Kohn, A.3
Gunnell, L.M.4
Honjo, T.5
Zuscik, M.J.6
O'Keefe, R.J.7
Hilton, M.J.8
-
17
-
-
84857304426
-
Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development
-
A. Kohn, Y. Dong, A. J. Mirando, A. M. Jesse, T. Honjo, M. J. Zuscik, R. J. O'Keefe, M. J. Hilton, Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development. Development 139, 1198-1212 (2012).
-
(2012)
Development
, vol.139
, pp. 1198-1212
-
-
Kohn, A.1
Dong, Y.2
Mirando, A.J.3
Jesse, A.M.4
Honjo, T.5
Zuscik, M.J.6
O'Keefe, R.J.7
Hilton, M.J.8
-
18
-
-
70149123248
-
Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development
-
T. J. Mead, K. E. Yutzey, Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development. Proc. Natl. Acad. Sci. U.S.A. 106, 14420-14425 (2009).
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 14420-14425
-
-
Mead, T.J.1
Yutzey, K.E.2
-
19
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
R. Kopan, M. X. Ilagan, The canonical Notch signaling pathway: Unfolding the activation mechanism. Cell 137, 216-233 (2009).
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
21
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
S. Artavanis-Tsakonas, M. D. Rand, R. J. Lake, Notch signaling: Cell fate control and signal integration in development. Science 284, 770-776 (1999).
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
22
-
-
0038082454
-
The distribution of Notch receptors and their ligands during articular cartilage development
-
A. J. Hayes, G. P. Dowthwaite, S. V. Webster, C. W. Archer, The distribution of Notch receptors and their ligands during articular cartilage development. J. Anat. 202, 495-502 (2003).
-
(2003)
J. Anat.
, vol.202
, pp. 495-502
-
-
Hayes, A.J.1
Dowthwaite, G.P.2
Webster, S.V.3
Archer, C.W.4
-
23
-
-
12144290483
-
The surface of articular cartilage contains a progenitor cell population
-
G. P. Dowthwaite, J. C. Bishop, S. N. Redman, I. M. Khan, P. Rooney, D. J. Evans, L. Haughton, Z. Bayram, S. Boyer, B. Thomson, M. S. Wolfe, C. W. Archer, The surface of articular cartilage contains a progenitor cell population. J. Cell Sci. 117, 889-897 (2004).
-
(2004)
J. Cell Sci.
, vol.117
, pp. 889-897
-
-
Dowthwaite, G.P.1
Bishop, J.C.2
Redman, S.N.3
Khan, I.M.4
Rooney, P.5
Evans, D.J.6
Haughton, L.7
Bayram, Z.8
Boyer, S.9
Thomson, B.10
Wolfe, M.S.11
Archer, C.W.12
-
24
-
-
84885168922
-
RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance
-
A. J. Mirando, Z. Liu, T. Moore, A. Lang, A. Kohn, A. M. Osinski, R. J. O'Keefe, R. A. Mooney, M. J. Zuscik, M. J. Hilton, RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance. Arthritis Rheum. 65, 2623-2633 (2013).
-
(2013)
Arthritis Rheum
, vol.65
, pp. 2623-2633
-
-
Mirando, A.J.1
Liu, Z.2
Moore, T.3
Lang, A.4
Kohn, A.5
Osinski, A.M.6
O'Keefe, R.J.7
Mooney, R.A.8
Zuscik, M.J.9
Hilton, M.J.10
-
25
-
-
84873156916
-
Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development
-
Y. Hosaka, T. Saito, S. Sugita, T. Hikata, H. Kobayashi, A. Fukai, Y. Taniguchi, M. Hirata, H. Akiyama, U. I. Chung, H. Kawaguchi, Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development. Proc. Natl. Acad. Sci. U.S.A. 110, 1875-1880 (2013).
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 1875-1880
-
-
Hosaka, Y.1
Saito, T.2
Sugita, S.3
Hikata, T.4
Kobayashi, H.5
Fukai, A.6
Taniguchi, Y.7
Hirata, M.8
Akiyama, H.9
Chung, U.I.10
Kawaguchi, H.11
-
26
-
-
84860297897
-
Expression patterns of Notch receptors and their ligands in human osteoarthritic and healthy articular cartilage
-
M. Mahjoub, N. Sassi, M. Driss, L. Laadhar, M. Allouche, M. Hamdoun, K. B. Romdhane, S. Sellami, S. Makni, Expression patterns of Notch receptors and their ligands in human osteoarthritic and healthy articular cartilage. Tissue Cell 44, 182-194 (2012).
-
(2012)
Tissue Cell
, vol.44
, pp. 182-194
-
-
Mahjoub, M.1
Sassi, N.2
Driss, M.3
Laadhar, L.4
Allouche, M.5
Hamdoun, M.6
Romdhane, K.B.7
Sellami, S.8
Makni, S.9
-
27
-
-
51349094632
-
Notch1, Jagged1, and HES5 are abundantly expressed in osteoarthritis
-
C. Karlsson, C. Brantsing, S. Egell, A. Lindahl, Notch1, Jagged1, and HES5 are abundantly expressed in osteoarthritis. Cells Tissues Organs 188, 287-298 (2008).
-
(2008)
Cells Tissues Organs
, vol.188
, pp. 287-298
-
-
Karlsson, C.1
Brantsing, C.2
Egell, S.3
Lindahl, A.4
-
28
-
-
67650032606
-
Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford study
-
G. Livshits, G. Zhai, D. J. Hart, B. S. Kato, H. Wang, F. M. Williams, T. D. Spector, Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford study. Arthritis Rheum. 60, 2037-2045 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2037-2045
-
-
Livshits, G.1
Zhai, G.2
Hart, D.J.3
Kato, B.S.4
Wang, H.5
Williams, F.M.6
Spector, T.D.7
-
29
-
-
84861712626
-
Interleukin-6, its role in fibrosing conditions
-
S. O'Reilly, M. Ciechomska, R. Cant, T. Hugle, J. M. van Laar, Interleukin-6, its role in fibrosing conditions. Cytokine Growth Factor Rev. 23, 99-107 (2012).
-
(2012)
Cytokine Growth Factor Rev.
, vol.23
, pp. 99-107
-
-
O'Reilly, S.1
Ciechomska, M.2
Cant, R.3
Hugle, T.4
Van Laar, J.M.5
-
30
-
-
84555205600
-
IL-6/IL-6 receptor system and its role in physiological and pathological conditions
-
M. Mihara, M. Hashizume, H. Yoshida, M. Suzuki, M. Shiina, IL-6/IL-6 receptor system and its role in physiological and pathological conditions. Clin. Sci. 122, 143-159 (2012).
-
(2012)
Clin. Sci.
, vol.122
, pp. 143-159
-
-
Mihara, M.1
Hashizume, M.2
Yoshida, H.3
Suzuki, M.4
Shiina, M.5
-
31
-
-
54449101331
-
IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-α and IL-17
-
M. Hashizume, N. Hayakawa, M. Mihara, IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-α and IL-17. Rheumatology 47, 1635-1640 (2008).
-
(2008)
Rheumatology
, vol.47
, pp. 1635-1640
-
-
Hashizume, M.1
Hayakawa, N.2
Mihara, M.3
-
32
-
-
78649906037
-
High molecular weight hyaluronic acid inhibits IL-6-induced MMP production from human chondrocytes by up-regulating the ERK inhibitor, MKP-1
-
M. Hashizume, M. Mihara, High molecular weight hyaluronic acid inhibits IL-6-induced MMP production from human chondrocytes by up-regulating the ERK inhibitor, MKP-1. Biochem. Biophys. Res. Commun. 403, 184-189 (2010).
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.403
, pp. 184-189
-
-
Hashizume, M.1
Mihara, M.2
-
33
-
-
20944436579
-
Osteoarthritis development in novel experimental mouse models induced by knee joint instability
-
S. Kamekura, K. Hoshi, T. Shimoaka, U. Chung, H. Chikuda, T. Yamada, M. Uchida, N. Ogata, A. Seichi, K. Nakamura, H. Kawaguchi, Osteoarthritis development in novel experimental mouse models induced by knee joint instability. Osteoarthritis Cartilage 13, 632-641 (2005).
-
(2005)
Osteoarthritis Cartilage
, vol.13
, pp. 632-641
-
-
Kamekura, S.1
Hoshi, K.2
Shimoaka, T.3
Chung, U.4
Chikuda, H.5
Yamada, T.6
Uchida, M.7
Ogata, N.8
Seichi, A.9
Nakamura, K.10
Kawaguchi, H.11
-
34
-
-
79958846369
-
Establishment of an index with increased sensitivity for assessing murine arthritis
-
E. R. Sampson, C. A. Beck, J. Ketz, K. L. Canary, M. J. Hilton, H. Awad, E. M. Schwarz, D. Chen, R. J. O'Keefe, R. N. Rosier, M. J. Zuscik, Establishment of an index with increased sensitivity for assessing murine arthritis. J. Orthop. Res. 29, 1145-1151 (2011).
-
(2011)
J. Orthop. Res.
, vol.29
, pp. 1145-1151
-
-
Sampson, E.R.1
Beck, C.A.2
Ketz, J.3
Canary, K.L.4
Hilton, M.J.5
Awad, H.6
Schwarz, E.M.7
Chen, D.8
O'Keefe, R.J.9
Rosier, R.N.10
Zuscik, M.J.11
-
35
-
-
0036901970
-
Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140 TrkA) in human osteoarthritic chondrocytes
-
F. Iannone, C. De Bari, F. Dell'Accio, M. Covelli, V. Patella, G. Lo Bianco, G. Lapadula, Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140 TrkA) in human osteoarthritic chondrocytes. Rheumatology 41, 1413-1418 (2002).
-
(2002)
Rheumatology
, vol.41
, pp. 1413-1418
-
-
Iannone, F.1
De Bari, C.2
Dell'Accio, F.3
Covelli, M.4
Patella, V.5
Lo Bianco, G.6
Lapadula, G.7
-
36
-
-
84861810351
-
Relationship between placenta growth factor 1 and vascularization, dehydroepiandrosterone sulfate to dehydroepiandrosterone conversion, or aromatase expression in patients with rheumatoid arthritis and patients with osteoarthritis
-
T. Lowin, C. Weidler, Z. Jenei-Lanzl, S. Capellino, C. G. Baerwald, F. Buttgereit, R. H. Straub, Relationship between placenta growth factor 1 and vascularization, dehydroepiandrosterone sulfate to dehydroepiandrosterone conversion, or aromatase expression in patients with rheumatoid arthritis and patients with osteoarthritis. Arthritis Rheum. 64, 1799-1808 (2012).
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1799-1808
-
-
Lowin, T.1
Weidler, C.2
Jenei-Lanzl, Z.3
Capellino, S.4
Baerwald, C.G.5
Buttgereit, F.6
Straub, R.H.7
-
37
-
-
84892464877
-
Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: Possible involvement in osteoarthritis pain
-
E. Pecchi, S. Priam, M. Gosset, A. Pigenet, L. Sudre, M. C. Laiguillon, F. Berenbaum, X. Houard, Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: Possible involvement in osteoarthritis pain. Arthritis Res. Ther. 16, R16 (2014).
-
(2014)
Arthritis Res. Ther.
, vol.16
, pp. R16
-
-
Pecchi, E.1
Priam, S.2
Gosset, M.3
Pigenet, A.4
Sudre, L.5
Laiguillon, M.C.6
Berenbaum, F.7
Houard, X.8
-
38
-
-
84904659936
-
Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study
-
Y. F. Ramos, W. den Hollander, J. V. Bovee, N. Bomer, R. van der Breggen, N. Lakenberg, J. C. Keurentjes, J. J. Goeman, P. E. Slagboom, R. G. Nelissen, S. D. Bos, I. Meulenbelt, Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study. PLOS One 9, e103056 (2014).
-
(2014)
PLOS One
, vol.9
-
-
Ramos, Y.F.1
Den Hollander, W.2
Bovee, J.V.3
Bomer, N.4
Van Der Breggen, R.5
Lakenberg, N.6
Keurentjes, J.C.7
Goeman, J.J.8
Slagboom, P.E.9
Nelissen, R.G.10
Bos, S.D.11
Meulenbelt, I.12
-
39
-
-
59649090734
-
Role of placenta growth factor and its receptor flt-1 in rheumatoid inflammation: A link between angiogenesis and inflammation
-
S. A. Yoo, H. J. Yoon, H. S. Kim, C. B. Chae, S. De Falco, C. S. Cho, W. U. Kim, Role of placenta growth factor and its receptor flt-1 in rheumatoid inflammation: A link between angiogenesis and inflammation. Arthritis Rheum. 60, 345-354 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 345-354
-
-
Yoo, S.A.1
Yoon, H.J.2
Kim, H.S.3
Chae, C.B.4
De Falco, S.5
Cho, C.S.6
Kim, W.U.7
-
40
-
-
33646362269
-
Regulator of G-protein signaling (RGS) proteins differentially control chondrocyte differentiation
-
C. T. Appleton, C. G. James, F. Beier, Regulator of G-protein signaling (RGS) proteins differentially control chondrocyte differentiation. J. Cell. Physiol. 207, 735-745 (2006).
-
(2006)
J. Cell. Physiol.
, vol.207
, pp. 735-745
-
-
Appleton, C.T.1
James, C.G.2
Beier, F.3
-
42
-
-
0035656866
-
Nitric oxide and inflammatory mediators in the perpetuation of osteoarthritis
-
S. B. Abramson, M. Attur, A. R. Amin, R. Clancy, Nitric oxide and inflammatory mediators in the perpetuation of osteoarthritis. Curr. Rheumatol. Rep. 3, 535-541 (2001).
-
(2001)
Curr. Rheumatol. Rep.
, vol.3
, pp. 535-541
-
-
Abramson, S.B.1
Attur, M.2
Amin, A.R.3
Clancy, R.4
-
43
-
-
0033166769
-
Reduction in the structural changes of experimental osteoarthritis by a nitric oxide inhibitor
-
J. Pelletier, D. Jovanovic, J. C. Fernandes, P. Manning, J. R. Connor, M. G. Currie, J. Martel-Pelletier, Reduction in the structural changes of experimental osteoarthritis by a nitric oxide inhibitor. Osteoarthritis Cartilage 7, 416-418 (1999).
-
(1999)
Osteoarthritis Cartilage
, vol.7
, pp. 416-418
-
-
Pelletier, J.1
Jovanovic, D.2
Fernandes, J.C.3
Manning, P.4
Connor, J.R.5
Currie, M.G.6
Martel-Pelletier, J.7
-
44
-
-
0033405584
-
Selective inhibition of inducible nitric oxide synthase in experimental osteoarthritis is associated with reduction in tissue levels of catabolic factors
-
J. P. Pelletier, V. Lascau-Coman, D. Jovanovic, J. C. Fernandes, P. Manning, J. R. Connor, M. G. Currie, J. Martel-Pelletier, Selective inhibition of inducible nitric oxide synthase in experimental osteoarthritis is associated with reduction in tissue levels of catabolic factors. J. Rheumatol. 26, 2002-2014 (1999).
-
(1999)
J. Rheumatol.
, vol.26
, pp. 2002-2014
-
-
Pelletier, J.P.1
Lascau-Coman, V.2
Jovanovic, D.3
Fernandes, J.C.4
Manning, P.5
Connor, J.R.6
Currie, M.G.7
Martel-Pelletier, J.8
-
45
-
-
0033166185
-
Nitric oxide in osteoarthritis
-
R. Studer, D. Jaffurs, M. Stefanovic-Racic, P. D. Robbins, C. H. Evans, Nitric oxide in osteoarthritis. Osteoarthritis Cartilage 7, 377-379 (1999).
-
(1999)
Osteoarthritis Cartilage
, vol.7
, pp. 377-379
-
-
Studer, R.1
Jaffurs, D.2
Stefanovic-Racic, M.3
Robbins, P.D.4
Evans, C.H.5
-
46
-
-
48549106755
-
The immunohistochemical localization of notch receptors and ligands in human articular cartilage, chondroprogenitor culture and ultrastructural characteristics of these progenitor cells
-
I. Ustunel, A. M. Ozenci, Z. Sahin, O. Ozbey, N. Acar, G. Tanriover, C. Celik-Ozenci, R. Demir, The immunohistochemical localization of notch receptors and ligands in human articular cartilage, chondroprogenitor culture and ultrastructural characteristics of these progenitor cells. Acta Histochem. 110, 397-407 (2008).
-
(2008)
Acta Histochem
, vol.110
, pp. 397-407
-
-
Ustunel, I.1
Ozenci, A.M.2
Sahin, Z.3
Ozbey, O.4
Acar, N.5
Tanriover, G.6
Celik-Ozenci, C.7
Demir, R.8
-
47
-
-
67649479387
-
Mesenchymal progenitor cell markers in human articular cartilage: Normal distribution and changes in osteoarthritis
-
S. P. Grogan, S. Miyaki, H. Asahara, D. D. Dlima, M. K. Lotz, Mesenchymal progenitor cell markers in human articular cartilage: Normal distribution and changes in osteoarthritis. Arthritis Res. Ther. 11, R85 (2009).
-
(2009)
Arthritis Res. Ther.
, vol.11
, pp. R85
-
-
Grogan, S.P.1
Miyaki, S.2
Asahara, H.3
Dlima, D.D.4
Lotz, M.K.5
-
48
-
-
40449084522
-
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
-
M. J. Hilton, X. Tu, X. Wu, S. Bai, H. Zhao, T. Kobayashi, H. M. Kronenberg, S. L. Teitelbaum, F. P. Ross, R. Kopan, F. Long, Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat. Med. 14, 306-314 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 306-314
-
-
Hilton, M.J.1
Tu, X.2
Wu, X.3
Bai, S.4
Zhao, H.5
Kobayashi, T.6
Kronenberg, H.M.7
Teitelbaum, S.L.8
Ross, F.P.9
Kopan, R.10
Long, F.11
-
49
-
-
59649088326
-
Involvement of the Notch pathway in the regulation of matrix metalloproteinase 13 and the dedifferentiation of articular chondrocytes in murine cartilage
-
R. Blaise, M. Mahjoub, C. Salvat, U. Barbe, C. Brou, M. T. Corvol, J. F. Savouret, F. Rannou, F. Berenbaum, P. Bausero, Involvement of the Notch pathway in the regulation of matrix metalloproteinase 13 and the dedifferentiation of articular chondrocytes in murine cartilage. Arthritis Rheum. 60, 428-439 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 428-439
-
-
Blaise, R.1
Mahjoub, M.2
Salvat, C.3
Barbe, U.4
Brou, C.5
Corvol, M.T.6
Savouret, J.F.7
Rannou, F.8
Berenbaum, F.9
Bausero, P.10
-
50
-
-
9144241202
-
Suppression of differentiation and proliferation of early chondrogenic cells by Notch
-
N. Watanabe, Y. Tezuka, K. Matsuno, S. Miyatani, N. Morimura, M. Yasuda, R. Fujimaki, K. Kuroda, Y. Hiraki, N. Hozumi, K. Tezuka, Suppression of differentiation and proliferation of early chondrogenic cells by Notch. J. Bone Miner. Metab. 21, 344-352 (2003).
-
(2003)
J. Bone Miner. Metab.
, vol.21
, pp. 344-352
-
-
Watanabe, N.1
Tezuka, Y.2
Matsuno, K.3
Miyatani, S.4
Morimura, N.5
Yasuda, M.6
Fujimaki, R.7
Kuroda, K.8
Hiraki, Y.9
Hozumi, N.10
Tezuka, K.11
-
51
-
-
84873974298
-
Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9
-
S. Chen, J. Tao, Y. Bae, M. M. Jiang, T. Bertin, Y. Chen, T. Yang, B. Lee, Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9. J. Bone Miner. Res. 28, 649-659 (2013).
-
(2013)
J. Bone Miner. Res.
, vol.28
, pp. 649-659
-
-
Chen, S.1
Tao, J.2
Bae, Y.3
Jiang, M.M.4
Bertin, T.5
Chen, Y.6
Yang, T.7
Lee, B.8
-
52
-
-
84857061462
-
Notch1 signaling regulates chondrogenic lineage determination through Sox9 activation
-
R. Haller, R. Schwanbeck, S. Martini, K. Bernoth, J. Kramer, U. Just, J. Rohwedel, Notch1 signaling regulates chondrogenic lineage determination through Sox9 activation. Cell Death Differ. 19, 461-469 (2012).
-
(2012)
Cell Death Differ
, vol.19
, pp. 461-469
-
-
Haller, R.1
Schwanbeck, R.2
Martini, S.3
Bernoth, K.4
Kramer, J.5
Just, U.6
Rohwedel, J.7
-
53
-
-
0032571268
-
Transcriptional roles of CCAAT/enhancer binding protein-β, nuclear factor-κB, and C-promoter binding factor 1 in interleukin (IL)-1β-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes
-
K. Miyazawa, A. Mori, K. Yamamoto, H. Okudaira, Transcriptional roles of CCAAT/enhancer binding protein-β, nuclear factor-κB, and C-promoter binding factor 1 in interleukin (IL)-1β-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes. J. Biol. Chem. 273, 7620-7627 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7620-7627
-
-
Miyazawa, K.1
Mori, A.2
Yamamoto, K.3
Okudaira, H.4
-
54
-
-
84858122464
-
Direct regulation of interleukin-6 expression by Notch signaling in macrophages
-
W. Wongchana, T. Palaga, Direct regulation of interleukin-6 expression by Notch signaling in macrophages. Cell. Mol. Immunol. 9, 155-162 (2012).
-
(2012)
Cell. Mol. Immunol.
, vol.9
, pp. 155-162
-
-
Wongchana, W.1
Palaga, T.2
-
55
-
-
84884973957
-
Interleukin 6 mediates selected effects of Notch in chondrocytes
-
S. Zanotti, E. Canalis, Interleukin 6 mediates selected effects of Notch in chondrocytes. Osteoarthritis Cartilage 21, 1766-1773 (2013).
-
(2013)
Osteoarthritis Cartilage
, vol.21
, pp. 1766-1773
-
-
Zanotti, S.1
Canalis, E.2
-
56
-
-
2942709503
-
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
-
S. Kamakura, K. Oishi, T. Yoshimatsu, M. Nakafuku, N. Masuyama, Y. Gotoh, Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat. Cell Biol. 6, 547-554 (2004).
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 547-554
-
-
Kamakura, S.1
Oishi, K.2
Yoshimatsu, T.3
Nakafuku, M.4
Masuyama, N.5
Gotoh, Y.6
-
57
-
-
84864374820
-
Attenuation of osteoarthritis via blockade of the SDF-1/CXCR4 signaling pathway
-
F. Wei, D. C. Moore, L. Wei, Y. Li, G. Zhang, X. Wei, J. K. Lee, Q. Chen, Attenuation of osteoarthritis via blockade of the SDF-1/CXCR4 signaling pathway. Arthritis Res. Ther. 14, R177 (2012).
-
(2012)
Arthritis Res. Ther.
, vol.14
, pp. R177
-
-
Wei, F.1
Moore, D.C.2
Wei, L.3
Li, Y.4
Zhang, G.5
Wei, X.6
Lee, J.K.7
Chen, Q.8
-
58
-
-
73649135324
-
Generation of aggrecan-CreERT2 knockin mice for inducible Cre activity in adult cartilage
-
S. P. Henry, C. W. Jang, J. M. Deng, Z. Zhang, R. R. Behringer, B. de Crombrugghe, Generation of aggrecan-CreERT2 knockin mice for inducible Cre activity in adult cartilage. Genesis 47, 805-814 (2009).
-
(2009)
Genesis
, vol.47
, pp. 805-814
-
-
Henry, S.P.1
Jang, C.W.2
Deng, J.M.3
Zhang, Z.4
Behringer, R.R.5
De Crombrugghe, B.6
-
59
-
-
0344736673
-
Notch signaling controls multiple steps of pancreatic differentiation
-
L. C. Murtaugh, B. Z. Stanger, K. M. Kwan, D. A. Melton, Notch signaling controls multiple steps of pancreatic differentiation. Proc. Natl. Acad. Sci. U.S.A. 100, 14920-14925 (2003).
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 14920-14925
-
-
Murtaugh, L.C.1
Stanger, B.Z.2
Kwan, K.M.3
Melton, D.A.4
-
60
-
-
0035691559
-
Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation
-
F. Long, X. M. Zhang, S. Karp, Y. Yang, A. P. McMahon, Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development 128, 5099-5108 (2001).
-
(2001)
Development
, vol.128
, pp. 5099-5108
-
-
Long, F.1
Zhang, X.M.2
Karp, S.3
Yang, Y.4
McMahon, A.P.5
-
61
-
-
24644494243
-
Direct regulation of intestinal fate by Notch
-
B. Z. Stanger, R. Datar, L. C. Murtaugh, D. A. Melton, Direct regulation of intestinal fate by Notch. Proc. Natl. Acad. Sci. U.S.A. 102, 12443-12448 (2005).
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 12443-12448
-
-
Stanger, B.Z.1
Datar, R.2
Murtaugh, L.C.3
Melton, D.A.4
-
62
-
-
26444545103
-
Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction
-
G. Belteki, J. Haigh, N. Kabacs, K. Haigh, K. Sison, F. Costantini, J. Whitsett, S. E. Quaggin, A. Nagy, Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Res. 33, e51 (2005).
-
(2005)
Nucleic Acids Res
, vol.33
, pp. e51
-
-
Belteki, G.1
Haigh, J.2
Kabacs, N.3
Haigh, K.4
Sison, K.5
Costantini, F.6
Whitsett, J.7
Quaggin, S.E.8
Nagy, A.9
-
63
-
-
34447639266
-
Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage
-
M. J. Hilton, X. Tu, F. Long, Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage. Dev. Biol. 308, 93-105 (2007).
-
(2007)
Dev. Biol.
, vol.308
, pp. 93-105
-
-
Hilton, M.J.1
Tu, X.2
Long, F.3
|