Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9

Journal of Bone and Mineral Research

Volumn 28, Issue 3, 2013, Pages 649-659

  Chen, Shan ^a   Tao, Jianning ^a   Bae, Yangjin ^a   Jiang, Ming Ming ^a   Bertin, Terry ^a   Chen, Yuqing ^a   Yang, Tao ^a   Lee, Brendan ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

AXIAL SKELETON; CHONDROCYTE; CHONDRODYSPLASIA; GENETIC MOUSE MODEL; NOTCH SIGNALING; SOX9

Indexed keywords

NOTCH RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RBPJ; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AXIS; BINDING SITE; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDRODYSPLASIA; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; GAIN OF FUNCTION MUTATION; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PHENOTYPE; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPINE MALFORMATION; TRANSCRIPTION REGULATION; VERTEBRA;

EID: 84873974298     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1770     Document Type: Article

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