Ac45 silencing mediated by AAV-sh-Ac45-RNAi prevents both bone loss and inflammation caused by periodontitis

Journal of Clinical Periodontology

Volumn 42, Issue 7, 2015, Pages 599-608

  Zhu, Zheng ^a,b   Chen, Wei ^b   Hao, Liang ^b   Zhu, Guochun ^b   Lu, Yun ^b   Li, Sheng ^a,b   Wang, Lin ^a   Li, Yi Ping ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b University of Alabama at Birmingham   (United States)

Author keywords

AAV mediated RNAi knockdown; Ac45; alveolar bone resorption; gene therapy; gingival inflammation; osteoclast immunology; periodontal disease

Indexed keywords

ATP6AP1 PROTEIN, MOUSE; AUTACOID; CYTOKINE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SMALL INTERFERING RNA;

ALVEOLAR BONE LOSS; ANIMAL; BACTEROIDACEAE INFECTION; BAGG ALBINO MOUSE; COMPARATIVE STUDY; DENDRITIC CELL; DEPENDOPARVOVIRUS; DISEASE MODEL; FEMALE; GENE SILENCING; GENETICS; GINGIVITIS; IMMUNOLOGY; INBRED MOUSE STRAIN; MACROPHAGE; MICROBIOLOGY; MOUSE; OSTEOCLAST; PERIODONTITIS; PHYSIOLOGY; PORPHYROMONAS GINGIVALIS; RNA INTERFERENCE; T LYMPHOCYTE;

ALVEOLAR BONE LOSS; ANIMALS; BACTEROIDACEAE INFECTIONS; CYTOKINES; DENDRITIC CELLS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; FEMALE; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; GINGIVITIS; INFLAMMATION MEDIATORS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED STRAINS; OSTEOCLASTS; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; RNA INTERFERENCE; RNA, SMALL INTERFERING; T-LYMPHOCYTES; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84937557211     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/jcpe.12415     Document Type: Article

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