Efficient gene transfer to periodontal ligament cells and human gingival fibroblasts by adeno-associated virus vectors

Journal of Dentistry

Volumn 37, Issue 7, 2009, Pages 502-508

  Kunze, Melanie ^a   Huber, Anke ^a   Krajewski, Anna ^a   Lowden, Esther ^a   Schuhmann, Natascha ^a   Buening, Hildegard ^a   Hallek, Michael ^a   Noack, Michael ^a   Perabo, Luca ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Adeno associated virus; Gene transfer; Human gingival fibroblasts; Periodontal ligament cells

Indexed keywords

GREEN FLUORESCENT PROTEIN; SINGLE STRANDED DNA;

ADENO ASSOCIATED VIRUS; ADOLESCENT; ADULT; ARTICLE; CELL CULTURE; CLASSIFICATION; COMPARATIVE STUDY; CYTOLOGY; EPITHELIUM CELL; FIBROBLAST; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE TRANSFER; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; GINGIVA; HUMAN; PERIODONTAL LIGAMENT; PLASMID; REPORTER GENE; SEROTYPING; TIME; TRANSGENE; VIRUS GENOME;

ADOLESCENT; ADULT; CELLS, CULTURED; DEPENDOVIRUS; DNA, SINGLE-STRANDED; EPITHELIAL CELLS; FIBROBLASTS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC VECTORS; GENOME, VIRAL; GINGIVA; GREEN FLUORESCENT PROTEINS; HUMANS; PERIODONTAL LIGAMENT; PLASMIDS; SEROTYPING; TIME FACTORS; TRANSDUCTION, GENETIC; TRANSGENES; YOUNG ADULT;

EID: 67349241919     PISSN: 03005712     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdent.2009.03.001     Document Type: Article

References (40)

1. Baum B.J., and O'Connell B.C. The impact of gene therapy on dentistry. Journal of the American Dental Association 126 (1995) 179-189
2. Verma I.M., and Weitzman M.D. Gene therapy: twenty-first century medicine. Annual Review of Biochemistry 74 (2005) 711-738
3. Anusaksathien O., Webb S.A., Jin Q.M., and Giannobile W.V. Platelet-derived growth factor gene delivery stimulates ex vivo gingival repair. Tissue Engineering 9 (2003) 745-756
4. Anusaksathien O., Jin Q., Zhao M., Somerman M.J., and Giannobile W.V. Effect of sustained gene delivery of platelet-derived growth factor or its antagonist (PDGF-1308) on tissue-engineered cementum. Journal of Periodontology 75 (2004) 429-440
5. Chen Q.P., and Giannobile W.V. Adenoviral gene transfer of PDGF downregulates gas gene product PDGFalphaR and prolongs ERK and Akt/PKB activation. American Journal of Physiology: Cell Physiology 282 (2002) C538-C544
6. Zhu Z., Lee C.S., Tejeda K.M., and Giannobile W.V. Gene transfer and expression of platelet-derived growth factors modulate periodontal cellular activity. Journal of Dental Research 80 (2001) 892-897
7. Giannobile W.V., Lee C.S., Tomala M.P., Tejeda K.M., and Zhu Z. Platelet-derived growth factor (PDGF) gene delivery for application in periodontal tissue engineering. Journal of Periodontology 72 (2001) 815-823
8. Jin Q., Anusaksathien O., Webb S.A., Printz M.A., and Giannobile W.V. Engineering of tooth-supporting structures by delivery of PDGF gene therapy vectors. Molecular Therapy 9 (2004) 519-526
9. Jin Q.M., Anusaksathien O., Webb S.A., Rutherford R.B., and Giannobile W.V. Gene therapy of bone morphogenetic protein for periodontal tissue engineering. Journal of Periodontology 74 (2003) 202-213
10. Dunn C.A., Jin Q., Taba Jr. M., Franceschi R.T., Bruce Rutherford R., and Giannobile W.V. BMP gene delivery for alveolar bone engineering at dental implant defects. Molecular Therapy 11 (2005) 294-299
11. Kanzaki H., Chiba M., Takahashi I., Haruyama N., Nishimura M., and Mitani H. Local OPG gene transfer to periodontal tissue inhibits orthodontic tooth movement. Journal of Dental Research 83 (2004) 920-925
12. Chen R., Kanzaki H., Chiba M., Nishimura M., Kanzaki R., and Igarashi K. Local osteoprotegerin gene transfer to periodontal tissue inhibits lipopolysaccharide-induced alveolar bone resorption. Journal of Periodontal Research 43 (2008) 237-245
13. Wu Z., Asokan A., and Samulski R.J. Adeno-associated virus serotypes: vector toolkit for human gene therapy. Molecular Therapy 14 (2006) 316-327
14. Grimm D., and Kay M.A. From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy. Current Gene Therapy 3 (2003) 281-304
15. Le Bec C., and Douar A.M. Gene therapy progress and prospects-vectorology: design and production of expression cassettes in AAV vectors. Gene Therapy 13 (2006) 805-813
16. Buning H., Perabo L., Coutelle O., Quadt-Humme S., and Hallek M. Recent developments in adeno-associated virus vector technology. Journal of Gene Medicine 10 (2008) 717-733
17. Grieger J.C., Choi V.W., and Samulski R.J. Production and characterization of adeno-associated viral vectors. Nature Protocols 1 (2006) 1412-1428
18. Monahan P.E., Jooss K., and Sands M.S. Safety of adeno-associated virus gene therapy vectors: a current evaluation. Expert Opinion on Drug Safety 1 (2002) 79-91
19. Coura Rdos S., and Nardi N.B. The state of the art of adeno-associated virus-based vectors in gene therapy. Virology Journal 4 (2007) 99
20. Mueller C., and Flotte T.R. Clinical gene therapy using recombinant adeno-associated virus vectors. Gene Therapy 15 (2008) 858-863
21. Jennings K., Miyamae T., Traister R., Marinov A., Katakura S., Sowders D., et al. Proteasome inhibition enhances AAV-mediated transgene expression in human synoviocytes in vitro and in vivo. Molecular Therapy 11 (2005) 600-607
22. Katakura S., Jennings K., Watanabe S., Adachi E., Thornton S., Gao G.P., et al. Recombinant adeno-associated virus preferentially transduces human, compared to mouse, synovium: implications for arthritis therapy. Moder Rheumatology 14 (2004) 18-24
23. Boissier M.C., Lemeiter D., Clavel C., Valvason C., Laroche L., Beque T., et al. Synoviocyte infection with adeno-associated virus (AAV) is neutralized by human synovial fluid from arthritis patients and depends on AAV serotype. Human Gene Therapy 18 (2007) 525-535
24. Adriaansen J., Vervoordeldonk M.J., and Tak P.P. Gene therapy as a therapeutic approach for the treatment of rheumatoid arthritis: innovative vectors and therapeutic genes. Rheumatology (Oxford) 45 (2006) 656-668
25. McCarty D.M. Self-complementary AAV vectors; advances and applications. Molecular Therapy 16 (2008) 1648-1656
26. Xiao X., Li J., and Samulski R.J. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. Journal of Virology 72 (1998) 2224-2232
27. Rabinowitz J.E., Rolling F., Li C., Conrath H., Xiao W., Xiao X., et al. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity. Journal of Virology 76 (2002) 791-801
28. Hacker U.T., Wingenfeld L., Kofler D.M., Schuhmann N.K., Lutz S., Herold T., et al. Adeno-associated virus serotypes 1 to 5 mediated tumor cell directed gene transfer and improvement of transduction efficiency. Journal of Gene Medicine 7 (2005) 1429-1438
29. Ramseier C.A., Abramson Z.R., Jin Q., and Giannobile W.V. Gene therapeutics for periodontal regenerative medicine. Dental Clinics of North America 50 (2006) 245-263
30. Karthikeyan B.V., and Pradeep A.R. Gene therapy in periodontics: a review and future implications. Journal of Contemporary Dental Practice 7 (2006) 83-91
31. Girod A., Ried M., Wobus C., Lahm H., Leike K., Kleinschmidt J., et al. Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2. Nature Medicine 5 (1999) 1438
32. Perabo L., Buning H., Kofler D.M., Ried M., Girod A., Wendtner C.M., et al. In vitro selection of viral vectors with modified tropism: the adeno-associated virus display. Molecular Therapy 8 (2003) 151-157
33. Muller O.J., Kaul F., Weitzman M.D., Pasqualini R., Arap W., Kleinschmidt J.A., et al. Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors. Nature Biotechnology 21 (2003) 1040-1046
34. Ghosh A., Yue Y., Lai Y., and Duan D. A hybrid vector system expands adeno-associated viral vector packaging capacity in a transgene-independent manner. Molecular Therapy 16 (2008) 124-130
35. Perabo L., Endell J., King S., Lux K., Goldnau D., Hallek M., et al. Combinatorial engineering of a gene therapy vector: directed evolution of adeno-associated virus. Journal of Gene Medicine 8 (2006) 155-162
36. Maheshri N., Koerber J.T., Kaspar B.K., and Schaffer D.V. Directed evolution of adeno-associated virus yields enhanced gene delivery vectors. Nature Biotechnology 24 (2006) 198-204
37. Erles K., Sebokova P., and Schlehofer J.R. Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV). Journal of Medical Virology 59 (1999) 406-411
38. Chirmule N., Propert K., Magosin S., Qian Y., Qian R., and Wilson J. Immune responses to adenovirus and adeno-associated virus in humans. Gene Therapy 6 (1999) 1574-1583
39. Moskalenko M., Chen L., van Roey M., Donahue B.A., Snyder R.O., McArthur J.G., et al. Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure. Journal of Virology 74 (2000) 1761-1766
40. Hauck B., Zhao W., High K., and Xiao W. Intracellular viral processing, not single-stranded DNA accumulation, is crucial for recombinant adeno-associated virus transduction. Journal of Virology 78 (2004) 13678-13686