V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption

Journal of Bone and Mineral Research

Volumn 27, Issue 8, 2012, Pages 1695-1707

  Yang, De Qin ^a,b,c,d   Feng, Shengmei ^a,b,e   Chen, Wei ^a,b   Zhao, Haibo ^f   Paulson, Christie ^a,b   Li, Yi Ping ^a,b  

^a University of Alabama at Birmingham   (United States)

^b FORSYTH INSTITUTE   (United States)

^c ZUNYI MEDICAL UNIVERSITY   (China)

^d CHONGQING MEDICAL UNIVERSITY   (China)

^e SHANGHAI JIAO TONG UNIVERSITY   (China)

^f UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

BONE RESORPTION; LYSOSOMAL TRAFFICKING; OSTEOCLAST; PROTEASE EXOCYTOSIS; V ATPase SUBUNIT ATP6AP1 (Ac45)

Indexed keywords

ACTIN; COLONY STIMULATING FACTOR 1; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN AC45; PROTEIN C FOS; PROTEINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; RAB7 PROTEIN; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL FUSION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; EXOCYTOSIS; LYSOSOME; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION;

ACIDS; ACTINS; ANIMALS; APOPTOSIS; BONE RESORPTION; CATHEPSIN K; CELL DIFFERENTIATION; CELL MEMBRANE; CELL PROLIFERATION; EXOCYTOSIS; EXTRACELLULAR SPACE; GENE KNOCKDOWN TECHNIQUES; LENTIVIRUS; LYSOSOMES; MICE; OSTEOCLASTS; OSTEOGENESIS; PROTEIN BINDING; PROTEIN SUBUNITS; PROTEIN TRANSPORT; RAB GTP-BINDING PROTEINS; RNA, SMALL INTERFERING; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84863989753     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1623     Document Type: Article

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