The Immune Modulation of B-Cell Responses by Porphyromonas gingivalis and Interleukin-10

Journal of Periodontology

Volumn 71, Issue 3, 2000, Pages 468-475

  Champaiboon, Chantrakorn ^a   Yongvanitchit, Kosol ^b   Pichyangkul, Sathit ^b   Mahanonda, Rangsini ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b ARMED FORCES RESEARCH INSTITUTE OF MEDICAL SCIENCES   (Thailand)

Author keywords

B lymphocytes; Interleukin 10; Killer cells, natural; Periodontal diseases microbiology; Porphyromonas gingivalis; T lymphocytes

Indexed keywords

CD69 ANTIGEN; DIAGNOSTIC AGENT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 15; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; RADIOPHARMACEUTICAL AGENT; T LYMPHOCYTE ANTIGEN; THYMIDINE; TRITIUM;

ADULT; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL DIVISION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; MACROPHAGE; MICROBIOLOGY; MONOCYTE; MONONUCLEAR CELL; NATURAL KILLER CELL; PERIODONTAL DISEASE; PORPHYROMONAS GINGIVALIS;

ADULT; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; B-LYMPHOCYTES; CELL DIVISION; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-15; KILLER CELLS, NATURAL; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MACROPHAGES; MONOCYTES; PERIODONTAL DISEASES; PORPHYROMONAS GINGIVALIS; RADIOPHARMACEUTICALS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; THYMIDINE; TRITIUM;

EID: 0034153216     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2000.71.3.468     Document Type: Article

References (45)

1. Seymour GJ, Gemmell E, Reinhardt RA, Eastcoot J, Taubman MA. Immunopathogenesis of chronic inflammatory periodontal disease: Cellular and molecular mechanisms. J Periodont Res 1993;28:478-486.
2. Ishikawa I, Nakashima K, Koseki T, et al. Induction of the immune response to periodontopathic bacteria and its role in the pathogenesis of periodontitis. Periodontol 2000 1997;14:79-111.
3. Gemmell E, Seymour GJ. Phenotypic analysis of B cells extracted from human periodontal disease tissue. Oral Microbiol Immunol 1991;6:356-362.
4. Bick PH, Carpenter AB, Holdeman LV, et al. Polyclonal B cell activation induced by extracts of Gram-negative bacteria isolated from periodontally diseased sites. Infect Immun 1981;34:43-49.
5. Tew J, Engel D, Mangan D. Polyclonal B-cell activation in periodontitis. J Periodont Res 1989;24:225-241.
6. Zambon JJ, Reynold HS, Slots J. Black-pigmented Bacteroides spp. in the human oral cavity. Infect Immun 1981;32:198-203.
7. Moore WEC, Holdeman LV, Smibert RM, Hash DE, Burmeister JA, Ranney RR. Bacteriology of severe periodontitis in young adult humans. Infect Immun 1982; 38:1137-1148.
8. Slots J, Listgarten MA. Bacteroides gingivalis, Bacteroides intermedius and Actinobacillus actinomycetemcomitans in human periodontal diseases. J Clin Periodontol 1988; 15:85-93.
9. Donaldson SL, Bick PH, Moore WC, Ranney RR, Burmeister JA, Tew JG. Polyclonal B cell activating capacities of gram-positive bacteria frequently isolated from periodontally diseased sites. J Periodont Res 1982;17:569-575.
10. Mangan DF, Won T, Lopatin DE. Non-specific induction of immunoglobulin M antibodies to periodontal disease-associated microorganisms after polyclonal human B-lymphocyte activation by Fusobacterium nucleatum. Infect Immun 1983;41:1038-1045.
11. Ftis A, Singh G, Dolby AE. Antibody to collagen type I in periodontal disease. J Periodontol 1986;57:693-698.
12. Hirsch HZ, Tarkowski A, Miller EJ, Gay S, Koopman WJ, Mestecky J. Autoimmunity to collagen in adult periodontal disease. J Oral Pathol 1988;17:456-459.
13. Fujihashi K, Beagley KW, Kono Y, et al. Gingival mononuclear cells from chronic inflammatory periodontal tissues produce interleukin (IL)-5 and IL-6 but not IL-2 and IL-4. Am J Pathol 1993;142:1239-1251.
14. Manhart SS, Reinhart RA, Payne JB, et al. Gingival cell IL-2 and IL-4 in early-onset periodontitis. J Periodontol 1994;65:807-813.
15. Yamazaki K, Nakajima T, Kubota Y, Gemmell E, Seymour GJ, Hara K. Cytokine messenger RNA expression in chronic inflammatory periodontal disease. Oral Microbiol Immunol 1997;12:281-287.
16. Fujihashi K, Yamamoto M, Hiroi T, Bamberg TV, McGhee JR, Kiyono H. Selected Th1 and Th2 cytokine mRNA expression by CD4+ T cells isolated from inflamed human gingival tissues. Clin Exp Med 1996;103:422-428.
17. Prabhu A, Michalowicz BS, Mathur A. Detection of local and systemic cytokines in adult periodontitis. J Periodontol 1996;67:515-522.
18. Gemmell E, Kjeldsen M, Yamazaki K, Nakajima T, Aldred MJ, Seymour GJ. Cytokine profiles of Porphyromonas gingivalis reactive T lymphocyte lines and clones derived from Porphyromonas gingivalis-infected subjects. Oral Dis 1995;1:139-146.
19. Salvi GE, Brown CE, Fujihashi H, et al. Inflammatory mediators of the terminal dentition in adult and early onset periodontitis. J Periodont Res 1998;33:212-225.
20. Aramaki M, Nagasawa T, Koseki T, Ishikawa I. Presence of activated B-1 cells in chronic inflamed gingival tissue. J Clin Immunol 1998;6:421-429.
21. De Waal Malefyt R, Yssel H, Roncarolo MG, Splits H, de Vries JE. Interleukin-10. Curr Opin Immunol 1992;4:314-320.
22. Rousset F, Garcia E, Defrance T, et al. Interleukin-10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci (USA) 1992; 89:1890-1893.
23. Boyum A. Isolation of leukocytes from human blood. Further observations. Scand J Clin Lab Invest 1968; 97(Suppl.):31-50.
24. Itoh K, Hirohata S. The role of IL-10 in human B cell activation, proliferation, and differentiation. J Immunol 1995;154:4341-4350.
25. Testi R, Phillips JH, Lanier LL. T cell activation via Leu23 (CD69). J Immunol 1989;143:1123-1128.
26. Maino VC, Sunti MA, Ruitenberg JJ. Rapid flow cytometric method for measuring lymphocyte subset activation. Cytometry 1995;20:127-133.
27. Santis AG, Lopez-Cabrera M, Sanchez-Madrid F, Proudfoot N. Expression of the early lymphocyte activation antigen CD69, a C-type lectin, is regulated by mRMA degradation associated with AU-rich sequence motifs. Eur J Immunol 1995;25:2142-2146.
28. Fujihashi K, Kono Y, Beagley KW, et al. Cytokines and periodontal disease: lmmunopathological role of interleukins for B cell responses in chronic inflamed gingival tissues. J Periodontol 1993;64(Suppl.):400-406.
29. Yamamoto M, Fujihashi K, Hiroi T, McGhee JR, Van Dyke TE, Kiyono H. Molecular and cellular mechanisms for periodontal diseases: Role of Th 1 and Th2 type cytokines in induction of mucosal inflammation. J Periodont Res 1997;32:115-119.
30. Moore KW, Vieira P, Fiorentino DF, Trounstine ML, Khan TA, Mosmann TR. Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science 1990;248:1230-1234.
31. De Waal Malefyt R, Hannen J, Splits H, et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 1991;174:915-924.
32. Mosmann TM. Properties and function of interleukin-10. Adv Immunol 1994;56:1-26.
33. Llorente L, Richaud-Patin Y, Wijdenes J, et al. Spontaneous production of interleukin-10 by B lymphocytes and monocytes in systemic lupus erythematosus. Eur Cytokine Netw 1993;4:421-430.
34. Llorente L, Richaud-Patin Y, Fio R, et al. In vivo production of interleukin-10 by non T cells in rheumatoid arthritis, Sjogren's syndrome, and systemic lupus erythematosus: A potential mechanism of B lymphocyte hyperactivity and autoimmunity. Arthritis Rheum 1994; 37:1647-1655.
35. Stein SH, Hart TE, Hoffman WH, Hendrix CL, Gustke CJ, Watson SC. Interleukin-10 promotes anticollagen antibody production in type I diabetic peripheral B lymphocytes. J Periodont Res 1997;32:189-195.
36. Laichalk LL, Danforth JM, Standiford TJ. Interleukin-10 inhibits neutrophil phagocytic and bactericidal activity. FEMS Immunol Med Microbiol 1996;15:181-187.
37. Jonsson R, Pitts A, Lue C, Gay S, Mestecky J. Immunoglobulin isotype distribution of locally produced autoantibodies to collagen type I in adult periodontitis. J Clin Periodontol 1991;18:703-707.
38. Hodgkin PD, Basten A. B cell activation, tolerance and antigen-presenting function. Curr Opin Immunol 1995; 7:121-129.
39. Serreze DV, Chapman HD, Varnum DS, et al. B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: Analysis of a new "speed congenic" stock of NOD.Ig mu null mice. J Exp Med 1996;184:2049-2053.
40. Moorchashm H, Noorchashm N, Kern J, Rostami SY, Barker CF, Naji A. B cells required for the initiation of insulitis and sialitis in nonobese diabetic mice. Diabetes 1997;46:941-946.
41. Falcone M, Lee J, Patstone G, Yeung B, Sarvetnick N. B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice. J Immunol 1998;161:1163-1168.
42. Wassenaar A, Reinhardus C, Thepen T, Abraham-Inpun L, Kievits F. Cloning, characterization, and antigen specificity of T-lymphocyte subsets extracted from gingival tissue of chronic adult periodontitis patients. Infect Immun 1995;63:2147-2153.
43. O'Neill PA, Woodson DL, Mackler BF. Functional characterization of human gingival lymphocytes: Cytotoxic activity. J Periodont Res 1982;17(1):50-59.
44. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996; 17:138-146.
45. Guery JC, Ria F, Galbiati F, Adorini L. Normal B cells fail to secrete interleukin-12. Eur J Immunol 1997; 27:1632-1639.