-
1
-
-
77958529521
-
Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens
-
Alexander B, Warner-Schmidt J, Eriksson T, Tamminga C, Arango-Lievano M, Ghose S, et al. Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens. Sci Transl Med. 2010 ; 2: 54ra76
-
(2010)
Sci Transl Med
, vol.2
-
-
Alexander, B.1
Warner-Schmidt, J.2
Eriksson, T.3
Tamminga, C.4
Arango-Lievano, M.5
Ghose, S.6
-
2
-
-
38849127573
-
Cathepsin K-dependent Toll-like receptor 9 signaling revealed in experimental arthritis
-
Asagiri M, Hirai T, Kunigami T, Kamano S, Gober HJ, Okamoto K, et al. Cathepsin K-dependent Toll-like receptor 9 signaling revealed in experimental arthritis. Science. 2008 ; 319: 624-627
-
(2008)
Science
, vol.319
, pp. 624-627
-
-
Asagiri, M.1
Hirai, T.2
Kunigami, T.3
Kamano, S.4
Gober, H.J.5
Okamoto, K.6
-
3
-
-
77952425348
-
IL-10 delivery by AAV5 vector attenuates inflammation in mice with Pseudomonas pneumonia
-
Buff SM, Yu H, McCall JN, Caldwell SM, Ferkol TW, Flotte TR, et al. IL-10 delivery by AAV5 vector attenuates inflammation in mice with Pseudomonas pneumonia. Gene Ther. 2010 ; 17: 567-576
-
(2010)
Gene Ther
, vol.17
, pp. 567-576
-
-
Buff, S.M.1
Yu, H.2
McCall, J.N.3
Caldwell, S.M.4
Ferkol, T.W.5
Flotte, T.R.6
-
4
-
-
19644368252
-
Adeno-associated virus vectors in clinical trials
-
Carter BJ. Adeno-associated virus vectors in clinical trials. Hum Gene Ther. 2005 ; 16: 541-550
-
(2005)
Hum Gene Ther
, vol.16
, pp. 541-550
-
-
Carter, B.J.1
-
5
-
-
33847283606
-
Novel pycnodysostosis mouse model uncovers cathepsin K function as a potential regulator of osteoclast apoptosis and senescence
-
Chen W, Yang S, Abe Y, Li M, Wang Y, Shao J, et al. Novel pycnodysostosis mouse model uncovers cathepsin K function as a potential regulator of osteoclast apoptosis and senescence. Hum Mol Genet. 2007 ; 16: 410-423
-
(2007)
Hum Mol Genet
, vol.16
, pp. 410-423
-
-
Chen, W.1
Yang, S.2
Abe, Y.3
Li, M.4
Wang, Y.5
Shao, J.6
-
6
-
-
62549149852
-
AAV2/1-TNFR:Fc gene delivery prevents periodontal disease progression
-
Cirelli JA, Park CH, MacKool K, Taba M, Lustig KH, Burstein H, et al. AAV2/1-TNFR:Fc gene delivery prevents periodontal disease progression. Gene Ther. 2009 ; 16: 426-436
-
(2009)
Gene Ther
, vol.16
, pp. 426-436
-
-
Cirelli, J.A.1
Park, C.H.2
MacKool, K.3
Taba, M.4
Lustig, K.H.5
Burstein, H.6
-
7
-
-
0033676265
-
Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritis
-
Cottard V, Mulleman D, Bouille P, Mezzina M, Boissier MC, Bessis N. Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritis. Gene Ther. 2000 ; 7: 1930-1939
-
(2000)
Gene Ther
, vol.7
, pp. 1930-1939
-
-
Cottard, V.1
Mulleman, D.2
Bouille, P.3
Mezzina, M.4
Boissier, M.C.5
Bessis, N.6
-
8
-
-
58249089414
-
Atp6v1c1 is an essential component of the osteoclast proton pump and in F-actin ring formation in osteoclasts
-
Feng S, Deng L, Chen W, Shao J, Xu G, Li YP. Atp6v1c1 is an essential component of the osteoclast proton pump and in F-actin ring formation in osteoclasts. Biochem J. 2009 ; 417: 195-203
-
(2009)
Biochem J
, vol.417
, pp. 195-203
-
-
Feng, S.1
Deng, L.2
Chen, W.3
Shao, J.4
Xu, G.5
Li, Y.P.6
-
9
-
-
0029809357
-
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
-
Gelb BD, Shi GP, Chapman HA, Desnick RJ. Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency. Science. 1996 ; 273: 1236-1238
-
(1996)
Science
, vol.273
, pp. 1236-1238
-
-
Gelb, B.D.1
Shi, G.P.2
Chapman, H.A.3
Desnick, R.J.4
-
10
-
-
0346216853
-
Local gene knockdown in the brain using viral-mediated RNA interference
-
Hommel JD, Sears RM, Georgescu D, Simmons DL, DiLeone RJ. Local gene knockdown in the brain using viral-mediated RNA interference. Nat Med. 2003 ; 9: 1539-1544
-
(2003)
Nat Med
, vol.9
, pp. 1539-1544
-
-
Hommel, J.D.1
Sears, R.M.2
Georgescu, D.3
Simmons, D.L.4
Dileone, R.J.5
-
11
-
-
0000060335
-
The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats
-
Kakehashi S, Stanley HR, Fitzgerald RJ. The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats. Oral Surg Oral Med Oral Pathol. 1965 ; 20: 340-349
-
(1965)
Oral Surg Oral Med Oral Pathol
, vol.20
, pp. 340-349
-
-
Kakehashi, S.1
Stanley, H.R.2
Fitzgerald, R.J.3
-
12
-
-
16544378960
-
IL-1alpha stimulates cathepsin K expression in osteoclasts via the tyrosine kinase-NF-kappaB pathway
-
Kamolmatyakul S, Chen W, Yang S, Abe Y, Moroi R, Ashique AM, et al. IL-1alpha stimulates cathepsin K expression in osteoclasts via the tyrosine kinase-NF-kappaB pathway. J Dent Res. 2004 ; 83: 791-796
-
(2004)
J Dent Res
, vol.83
, pp. 791-796
-
-
Kamolmatyakul, S.1
Chen, W.2
Yang, S.3
Abe, Y.4
Moroi, R.5
Ashique, A.M.6
-
13
-
-
34250683023
-
Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: An open label, phase i trial
-
Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA, et al. Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet. 2007 ; 369: 2097-2105
-
(2007)
Lancet
, vol.369
, pp. 2097-2105
-
-
Kaplitt, M.G.1
Feigin, A.2
Tang, C.3
Fitzsimons, H.L.4
Mattis, P.5
Lawlor, P.A.6
-
14
-
-
33748788554
-
B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease
-
Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux NY, et al. B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease. Am J Pathol. 2006 ; 169: 987-998
-
(2006)
Am J Pathol
, vol.169
, pp. 987-998
-
-
Kawai, T.1
Matsuyama, T.2
Hosokawa, Y.3
Makihira, S.4
Seki, M.5
Karimbux, N.Y.6
-
15
-
-
33645801215
-
Substance P stimulates release of RANKL via COX-2 expression in human dental pulp cells
-
Kojima T, Yamaguchi M, Kasai K. Substance P stimulates release of RANKL via COX-2 expression in human dental pulp cells. Inflamm Res. 2006 ; 55: 78-84
-
(2006)
Inflamm Res
, vol.55
, pp. 78-84
-
-
Kojima, T.1
Yamaguchi, M.2
Kasai, K.3
-
16
-
-
79251502922
-
Antibody to receptor activator of NF-kappaB ligand ameliorates T cell-mediated periodontal bone resorption
-
Lin X, Han X, Kawai T, Taubman MA. Antibody to receptor activator of NF-kappaB ligand ameliorates T cell-mediated periodontal bone resorption. Infect Immun. 2011 ; 79: 911-917
-
(2011)
Infect Immun
, vol.79
, pp. 911-917
-
-
Lin, X.1
Han, X.2
Kawai, T.3
Taubman, M.A.4
-
17
-
-
33745907268
-
RNAi-mediated silencing of estrogen receptor A in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors
-
Musatov S, Chen W, Pfaff DW, Kaplitt MG, Ogawa S. RNAi-mediated silencing of estrogen receptor A in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors. Proc Natl Acad Sci USA. 2006 ; 103: 10456-10460
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10456-10460
-
-
Musatov, S.1
Chen, W.2
Pfaff, D.W.3
Kaplitt, M.G.4
Ogawa, S.5
-
18
-
-
0031061790
-
Apical periodontitis: A dynamic encounter between root canal infection and host response
-
121-148
-
Nair PN. Apical periodontitis: a dynamic encounter between root canal infection and host response. Periodontol. 1997 ; 2000: 13 121-148
-
(1997)
Periodontol
, vol.2000
, pp. 13
-
-
Nair, P.N.1
-
19
-
-
22544468953
-
Pathogenesis of apical periodontitis and the causes of endodontic failures
-
Nair PN. Pathogenesis of apical periodontitis and the causes of endodontic failures. Crit Rev Oral Biol Med. 2004 ; 15: 348-381
-
(2004)
Crit Rev Oral Biol Med
, vol.15
, pp. 348-381
-
-
Nair, P.N.1
-
20
-
-
66849115049
-
IL-17 is involved in bone resorption in mouse periapical lesions
-
Oseko F, Yamamoto T, Akamatsu Y, Kanamura N, Iwakura Y, Imanishi J, et al. IL-17 is involved in bone resorption in mouse periapical lesions. Microbiol Immunol. 2009 ; 53: 287-294
-
(2009)
Microbiol Immunol
, vol.53
, pp. 287-294
-
-
Oseko, F.1
Yamamoto, T.2
Akamatsu, Y.3
Kanamura, N.4
Iwakura, Y.5
Imanishi, J.6
-
21
-
-
17444424970
-
Experimental arthritis in rats induces biomarkers of periodontitis which are ameliorated by gene therapy with tissue inhibitor of matrix metalloproteinases
-
Ramamurthy NS, Greenwald RA, Celiker MY, Shi EY. Experimental arthritis in rats induces biomarkers of periodontitis which are ameliorated by gene therapy with tissue inhibitor of matrix metalloproteinases. J Periodontol. 2005 ; 76: 229-233
-
(2005)
J Periodontol
, vol.76
, pp. 229-233
-
-
Ramamurthy, N.S.1
Greenwald, R.A.2
Celiker, M.Y.3
Shi, E.Y.4
-
22
-
-
0034292422
-
IL-10, but not IL-4, suppresses infection-stimulated bone resorption in vivo
-
Sasaki H, Hou L, Belani A, Wang CY, Uchiyama T, Muller R, et al. IL-10, but not IL-4, suppresses infection-stimulated bone resorption in vivo. J Immunol. 2000 ; 165: 3626-3630
-
(2000)
J Immunol
, vol.165
, pp. 3626-3630
-
-
Sasaki, H.1
Hou, L.2
Belani, A.3
Wang, C.Y.4
Uchiyama, T.5
Muller, R.6
-
23
-
-
0025448374
-
Role of immune cytokines in the pathogenesis of periapical lesions
-
Stashenko P. Role of immune cytokines in the pathogenesis of periapical lesions. Endod Dent Traumatol. 1990 ; 6: 89-96
-
(1990)
Endod Dent Traumatol
, vol.6
, pp. 89-96
-
-
Stashenko, P.1
-
24
-
-
68249152387
-
Dental pulp and periodontal ligament cells support osteoclastic differentiation
-
Uchiyama M, Nakamichi Y, Nakamura M, Kinugawa S, Yamada H, Udagawa N, et al. Dental pulp and periodontal ligament cells support osteoclastic differentiation. J Dent Res. 2009 ; 88: 609-614
-
(2009)
J Dent Res
, vol.88
, pp. 609-614
-
-
Uchiyama, M.1
Nakamichi, Y.2
Nakamura, M.3
Kinugawa, S.4
Yamada, H.5
Udagawa, N.6
-
25
-
-
34248580633
-
Gene therapy methods in bone and joint disorders. Evaluation of the adeno-associated virus vector in experimental models of articular cartilage disorders, periprosthetic osteolysis and bone healing
-
Ulrich-Vinther M. Gene therapy methods in bone and joint disorders. Evaluation of the adeno-associated virus vector in experimental models of articular cartilage disorders, periprosthetic osteolysis and bone healing. Acta Orthop Suppl. 2007 ; 78: 1-64
-
(2007)
Acta Orthop Suppl
, vol.78
, pp. 1-64
-
-
Ulrich-Vinther, M.1
-
26
-
-
0027568358
-
Characterization of bone-resorbing activity in human periapical lesions
-
Wang CY, Stashenko P. Characterization of bone-resorbing activity in human periapical lesions. J Endod. 1993 ; 19: 107-111
-
(1993)
J Endod
, vol.19
, pp. 107-111
-
-
Wang, C.Y.1
Stashenko, P.2
-
27
-
-
33748080101
-
RANKL increase in compressed periodontal ligament cells from root resorption
-
Yamaguchi M, Aihara N, Kojima T, Kasai K. RANKL increase in compressed periodontal ligament cells from root resorption. J Dent Res. 2006 ; 85: 751-756
-
(2006)
J Dent Res
, vol.85
, pp. 751-756
-
-
Yamaguchi, M.1
Aihara, N.2
Kojima, T.3
Kasai, K.4
-
28
-
-
34447514412
-
RGS10-null mutation impairs osteoclast differentiation resulting from the loss of [Ca2+]i oscillation regulation
-
Yang S, Li YP. RGS10-null mutation impairs osteoclast differentiation resulting from the loss of [Ca2+]i oscillation regulation. Genes Dev. 2007 ; 21: 1803-1816
-
(2007)
Genes Dev
, vol.21
, pp. 1803-1816
-
-
Yang, S.1
Li, Y.P.2
-
29
-
-
79953774682
-
Anti-inflammatory effect of MAPK phosphatase-1 local gene transfer in inflammatory bone loss
-
Yu H, Li Q, Herbert B, Zinna R, Martin K, Junior CR, et al. Anti-inflammatory effect of MAPK phosphatase-1 local gene transfer in inflammatory bone loss. Gene Ther. 2011 ; 18: 344-353
-
(2011)
Gene Ther
, vol.18
, pp. 344-353
-
-
Yu, H.1
Li, Q.2
Herbert, B.3
Zinna, R.4
Martin, K.5
Junior, C.R.6
-
30
-
-
77957990313
-
Cell-based osteoprotegerin therapy for debris-induced aseptic prosthetic loosening on a murine model
-
Zhang L, Jia TH, Chong AC, Bai L, Yu H, Gong W, et al. Cell-based osteoprotegerin therapy for debris-induced aseptic prosthetic loosening on a murine model. Gene Ther. 2010 ; 17: 1262-1269
-
(2010)
Gene Ther
, vol.17
, pp. 1262-1269
-
-
Zhang, L.1
Jia, T.H.2
Chong, A.C.3
Bai, L.4
Yu, H.5
Gong, W.6
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