Activation of lysophosphatidic acid receptor type 1 contributes to pathophysiology of spinal cord injury

Journal of Neuroscience

Volumn 35, Issue 28, 2015, Pages 10224-102035

  Santos Nogueira, Eva ^a   López Serrano, Clara ^a   Hernández, Joaquim ^a   Lago, Natalia ^b   Astudillo, Alma M ^c   Balsinde, Jesús ^c   Estivill Torrús, Guillermo ^d   de Fonseca, Fernando Rodriguez ^d   Chun, Jerold ^e   López Vales, Rubèn ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

^c University of Valladolid   (Spain)

^d HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Demyelination; Lysophosphatidic acid; Microglia; Neuroprotection; Oligodendrocytes; Spinal cord injury

Indexed keywords

LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHATIDIC ACID RECEPTOR 1; RECEPTOR BLOCKING AGENT; SODIUM {4’ [3 METHYL 4 ((R) 1 PHENYL ETHOXYCARBONYLAMINO) ISOXAZOL 5 YL] BIPHENYL 4 YL} ACETATE; UNCLASSIFIED DRUG; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHOLIPID;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL ISOLATION; CELL SURVIVAL; CONTROLLED STUDY; DEMYELINATION; ELECTRON MICROSCOPY; EVOKED MUSCLE RESPONSE; FEMALE; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOFLUORESCENCE MICROSCOPY; LOCOMOTION; MACROPHAGE ACTIVATION; MASS SPECTROMETRY; MICROGLIA; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OLIGODENDROGLIA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN CORTEX; C57BL MOUSE; CELL DEATH; COMPLICATION; CYTOLOGY; DEFICIENCY; DEMYELINATING DISEASES; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; MOTOR ACTIVITY; NEWBORN; PATHOLOGY; SPINAL CORD; SPINAL CORD INJURIES; TIME; TRANSGENIC MOUSE; ULTRASTRUCTURE;

ANIMALS; ANIMALS, NEWBORN; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; EVOKED POTENTIALS, MOTOR; FEMALE; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MOTOR ACTIVITY; OLIGODENDROGLIA; RECEPTORS, LYSOPHOSPHATIDIC ACID; SPINAL CORD; SPINAL CORD INJURIES; TIME FACTORS;

EID: 84937551043     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4703-14.2015     Document Type: Article

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