Lysophosphatidylcholine induces rapid recruitment and activation of macrophages in the adult mouse spinal cord

GLIA

Volumn 30, Issue 1, 2000, Pages 92-104

  Ousman, Shalina S ^a   David, Samuel ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

Demyelination; Lysolecithin; Microglia; Monocytes; Neutrophils; Spinal cord; T Cells

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; LYSOPHOSPHATIDYLCHOLINE; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BLOOD BRAIN BARRIER; CAPILLARY PERMEABILITY; CYTOLOGY; DRUG EFFECT; FEMALE; MACROPHAGE; METABOLISM; MICROINJECTION; MOUSE; PHYSIOLOGY; SPINAL CORD; T LYMPHOCYTE; TIME;

ANIMALS; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; FEMALE; INTERCELLULAR ADHESION MOLECULE-1; LYSOPHOSPHATIDYLCHOLINES; MACROPHAGES; MICE; MICE, INBRED BALB C; MICROINJECTIONS; SPINAL CORD; T-LYMPHOCYTES; TIME FACTORS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0034022189     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(200003)30:1<92::AID-GLIA10>3.0.CO;2-W     Document Type: Article

References (46)

1. Acarin L, Gonzalez B, Castellano B, Castro AJ. 1996. Microglial response to N-methyl-D-aspartate-mediated excitotoxicity in the immature rat brain. J Comp Neurol 367:361-374.
2. Allen SJ, Baker D, O'Neill JK, Davison AN, Turk JL. 1993. Isolation and characterization of cells infiltrating the spinal cord during the course of chronic relapsing experimental allergic encephalomyelitis in the Biozzi AB/H mouse. Cell Immunol 146:335-350.
3. Avellino AM, Hart D, Dailey AT, MacKinnon M, Ellegala D, Kliot M. 1995. Differential macrophage responses in the peripheral and central nervous system during Wallerian degeneration of axons. Exp Neurol 136:183-198.
4. Bauer J, Huitinga I, Zhao W, Lassmann H, Hickey WF, Dijkstra CD. 1995. The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis. Glia 15:437-446.
5. Begolka WS, Miller SD. 1998. Cytokines as intrinsic and exogenous regulators of pathogenesis in experimental autoimmune encephalomyelitis. Res Immunol 149:771-781.
6. Beuche W, Friede RL. 1984. The role of non-resident cells in Wallerian degeneration. J Neurocytol 13:767-796.
7. Bignami A, Ralston HJ III. 1969. The cellular reaction to Wallerian degeneration in the central nervous system of the cat. Brain Res 13:444-461.
8. Blakemore WF, Eames RA, Smith KJ, McDonald WI. 1977. Remyelination in the spinal cord of the cat after intraspinal injections of lysolecithin. J Neurol Sci 33:31-43.
9. Blakemore WF. 1978. Observations on remyelination in the rabbit spinal cord following demyelination induced by lysolecithin. Neuropathol App Neurobiol 4:47-59.
10. Bruck W. 1997. The role of macrophages in Wallerian degeneration. Brain Pathol 7:741-752.
11. Crang AJ, Blakemore WF. 1986. Observations on Wallerian degeneration in explant cultures of cat sciatic nerve. J Neurocytol 15:471-482.
12. Frank M, Wolburg H. 1996. Cellular reactions at the lesion site after crushing of the rat optic nerve. Glia 16:227-240.
13. Franson P, Ronnevi L-O. 1984. Myelin breakdown and elimination in the posterior funiculus of the adult cat after dorsal rhizotomy: a light and electron microscopic qualitative and quantitative study. J Comp Neurol 223:138-151.
14. George R, Griffin JW. 1994. Delayed macrophage responses and myelin clearance during Wallerian degeneration in the central nervous system: the dorsal radiculotomy model. Exp Neurol 129: 225-236.
15. Giulian D, Chen J, Ingeman JE, George JK, Noponen M. 1989. The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain. J Neurosci 9:4416-4429.
16. Gregson NA. 1989. Lysolipids and membrane damage: lysolecithin and its interaction with myelin. Biochem Soc Trans 17:280-283.
17. Griffin JW, George R, Lobato C, Tyor WR, Yan LC, Glass JD. 1992. Macrophage responses and myelin clearance during Wallerian degeneration: relevance to immune-mediated demyelination. J Neuroimmunol 40:153-166.
18. Hall SM. 1972. The effect of injections of lysophosphatidylcholine into white matter of the adult mouse spinal cord. J Cell Sci 10:535-546.
19. Hirschberg DL, Schwartz M. 1995. Macrophage recruitment to acutely injured central nervous system is inhibited by a resident factor: a basis for an immune-brain barrier. J Neuroimmunol 61: 89-96.
20. Hirschberg DL, Moalem G, He J, Mor F, Cohen IR, Schwartz M. 1998. Accumulation of passively transferred primed T cells independently of their antigen specificity following central nervous system trauma. J Neuroimmunol 89:88-96.
21. Hoffman LM, Karpus WJ. 1998. Chemokine regulation of CNS T-cell infiltration in experimental autoimmune encephalomyelitis. Res Immunol 149:790-794.
22. Huitinga I, van Rooijen N, de Groot CJA, Uitdehaag BMJ, Dijkstra CD. 1990. Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J Exp Med 172: 1025-1033.
23. Huitinga I, Ruuls SR, Jung S, van Rooijen N, Hartung H-P, Dijkstra CD. 1995. Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats. Clin Exp Immunol 100:344-351.
24. Jeffrey ND, Blakemore WF. 1995. Remyelination of mouse spinal cord axons demyelinated by local injection of lysolecithin. J Neurocytol 24:775-781.
25. Kaji A, Imai H, Maeda T, Watanabe S. 1986. Demonstration of sensory cutaneous nerve fibers in guinea pig lip using endogenous oxidase histochemistry. Histochemistry 85:203-208.
26. Karpus WJ, Ransohoff RM. 1998. Cutting edge commentary: chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis. J Immunol 161:2667-2671.
27. Klusman I, Schwab ME. 1997. Effects of pro-inflammatory cytokines in experimental spinal cord injury. Brain Res 762:173-184.
28. Kume N, Cybulsky MI, Gimbrone MA Jr. 1992. Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest 90:1138-1144.
29. Lawson LJ, Perry VH, Dri P, Gordon S. 1990. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 39:151-170.
30. Lawson LJ, Perry VH, Gordon S. 1992. Turnover of resident microglia in the normal adult mouse brain. Neuroscience 48:405-415.
31. Lawson LJ, Frost L, Risbridger J, Fearn S, Perry VH. 1994. Quantification of the mononuclear phagocyte response to Wallerian degeneration of the optic nerve. J Neurocytol 23:729-744.
32. Liu KM, Shen CL. 1985. Ultrastructural sequence of myelin breakdown during Wallerian degeneration in the rat optic nerve. Cell Tissue Res 242:245-256.
33. Maatta JA, Sjoholm UR, Nygardas PT, Salmi AA, Hinkkanen AE. 1998. Neutrophils secreting tumour necrosis factor alpha infiltrate the central nervous system of BALB/c mice with experimental autoimmune encephalomyelitis. J Neuroimmunol 90:162-175.
34. Perry VH, Brown MC, Gordon S. 1987. The macrophage response to central and peripheral nerve injury. J Exp Med 165:1218-1223.
35. Perry VH, Andersson P-B, Gordon S. 1993. Macrophages and inflammation in the central nervous system. TINS 16:268-273.
36. Quinn MT, Parthasarathy S, Steinberg D. 1988. Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis. Proc Natl Acad Sci USA 85:2805-2809.
37. Reichert F, Rotshenker S. 1996. Deficient activation of microglia during optic nerve degeneration. J Neuroimmunol 70:153-161.
38. Schnell L, Fearn S, Schwab ME, Perry VH, Anthony DC. 1999. Cytokine-induced acute inflammation in the brain and spinal cord. J Neuropathol Exp Neurol 58:245-254.
39. Stoll G, Trapp BD, Griffin JW. 1989. Macrophage function during Wallerian degeneration of rat optic nerve: clearance of degenerating myelin and Ia expression. J Neurosci 9:2327-2335.
40. Swanborg RH. 1995. Experimental autoimmune encephalomyelitis in rodents as a model for human demyelinating disease. Clin Immunol Immunopathol 77:4-13.
41. Tran EH, Hoekstra K, van Rooijen N, Dijkstra CD, Owens T. 1998. Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J Immunol 161:3767-3775.
42. Triarhou LC, Herndon RM. 1985. Effect of macrophage inactivation on the neuropathology of lysolecithin-induced demyelination. Br J Exp Pathol 66:293-301.
43. Triarhou LC, Herndon RM. 1986. The effect of dexamethasone on L-alpha-lysophosphatidylcholine (lysolecithin)-induced demyelination of the rat spinal cord. Arch Neurol 43:121-125.
44. Wekerle H, Schwab M, Linington C, Meyermann R. 1986. Antigen presentation in the peripheral nervous system: Schwann cells present endogenous myelin autoantigens to lymphocytes. Eur J Immunol 16:1551-1557.
45. Zeev-Brann AB, Lazarov-Spiegler O, Brenner T, Schwartz M. 1998. Differential effects of central and peripheral nerves on macrophages and microglia. Glia 23:181-190.
46. Zeine R, Owens T. 1992. Direct demonstration of the infiltration of murine central nervous system by Pgp-1/CD44 high CD45RB (low) CD4+ T cells that induce experimental allergic encephalomyelitis. J Neuroimmunol 40:57-69.