Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

Human Molecular Genetics

Volumn 21, Issue 15, 2012, Pages 3500-3512

  Coppola, Giovanni ^a,b   Chinnathambi, Subashchandrabose ^f   Lee, Jason JiYong ^a   Dombroski, Beth A ^g   Baker, Matt C ^h   Soto Ortolaza, Alexandra I ^h   Lee, Suzee E ^c   Klein, Eric ^a   Huang, Alden Y ^a   Sears, Renee ^a   Lane, Jessica R ^a   Karydas, Anna M ^c   Kenet, Robert O ⁱ   Biernat, Jacek ^f   Wang, Li San ^g   Cotman, Carl W ^d,bj   DeCarli, Charles S ^e   Levey, Allan I ^j   Ringman, John ^a   Mendez, Mario F ^a   Chui, Helena C ^k   Le Ber, Isabelle ^m,n   Brice, Alexis ^m,o   Lupton, Michelle K ^p   Preza, Elisavet ^p   Lovestone, Simon ^p   Powell, John ^p   Graff Radford, Neill ^h   Petersen, Ronald C ^q,aw   Boeve, Bradley F ^q,aw   Lippa, Carol F ^r   Bigio, Eileen H ^s   Mackenzie, Ian ^t   Finger, Elizabeth ^u   Kertesz, Andrew ^u   Caselli, Richard J ^v   Gearing, Marla ^j,bs   Juncos, Jorge L ^j   Ghetti, Bernardino ^w,bp   Spina, Salvatore ^w,bp   Bordelon, Yvette M ^a   W Tourtellotte, Wallace ^x   Frosch, Matthew P ^y,av   Vonsattel, Jean Paul G ^z,aa   Zarow, Chris ^l   Beach, Thomas G ^ab   Albin, Roger L ^ac,ad   Lieberman, Andrew P ^ac,ad   Lee, Virginia M ^g   Trojanowsk, John Q ^g   Van Deerlin, Vivianna M ^g   Bird, Thomas D ^ae,af   Galasko, Douglas R ^ag,ah   Masliah, Eliezer ^ag,ah   White, Charles L ^ai   Troncoso, Juan C ^aj   Hannequin, Didier ^ak   Boxer, Adam L ^c,ay   Geschwind, Michael D ^c   Kumar, Satish ^f   Mandelkow, Eva Maria ^f   Wszolek, Zbigniew K ^h   Uitti, Ryan J ^h   Dickson, Dennis W ^h,bf   Haines, Jonathan L ^al   Mayeux, Richard ^z,aa   Pericak Vance, Margaret A ^am   Farrer, Lindsay A ^an,ao,ap   Apostolova, Liana G ^a,ap   Arnold, Steven E ^g   T Baldwin, Clinton ^ao   Barber, Robert ^aq   Barmada, Michael M ^ar   Beach, Thomas ^ab   Beecham, Gary W ^am   Beekly, Duane ^af   Bennett, David A ^as,at   Blacker, Deborah ^au,av   Bowen, James D ^ax   Burke, James R ^az   Buros, Jacqueline ^ao   Buxbaum, Joseph D ^ba   Cairns, Nigel J ^bb   Cantwell, Laura B ^g   Cao, Chuanhai ^bc   Carlson, Chris S ^bd   Carney, Regina M ^be   Carrasquillo, Minerva M ^bf   Carroll, Steven L ^bg   Clark, David G ^bh   Corneveaux, Jason ^bi   Crane, Paul K ^ae   Cruchaga, Carlos ^bb   Cummings, Jeffrey L ^a   De Jager, Philip L ^bk,bl   DeCarli, Charles ^e   DeKosky, Steven T ^bm   Demirci, F Yesim ^ar   Diaz Arrastia, Ramon ^ai   Dick, Malcolm ^bj   Duara, Ranjan ^bn   Ellis, William G ^e   Ertekin Taner, Nilufer N ^h,bf   Evans, Denis ^bo   Faber, Kelley M ^bp   Fallon, Kenneth B ^bg   Farlow, Martin R ^bp   Ferris, Steven ^bq   Foroud, Tatiana M ^bp   Gallins, Paul J ^am   Ganguli, Mary ^br   Gilbert, John R ^am   Gilman, Sid ^ac   Giordani, Bruno ^bu   Glass, Jonathan D ^j   Goate, Alison M ^bb   Graff Radford, Neill R ^h,bf   Green, Robert C ^ao,ap   Growdon, John H ^av   Hakonarson, Hakon ^bv   Hamilton, Ronald L ^br   Hardy, John ^bw   Harrell, Lindy E ^bh   Head, Elizabeth ^bj   Honig, Lawrence S ^z   Huentelman, Matthew J ^bi   Hulette, Christine M ^az   Hyman, Bradley T ^av   Jarvik, Gail P ^af   Jicha, Gregory A ^bx   Jin, Lee Way ^e   Johnson, Nancy ^s   Jun, Gyungah ^an,ao   Kamboh, M Ilyas ^ar   Karlawish, Jason ^g   Karydas, Anna ^ay   Kauwe, John S K ^by   Kaye, Jeffrey A ^bz,ca   Kim, Ronald ^d   Koo, Edward H ^ah   Kowall, Neil W ^ao   Kramer, Patricia ^bz,cb   Kukull, Walter A ^af   Lah, James J ^j   Larson, Eric B ^cc   Lopez, Oscar L ^ar   Lunetta, Kathryn L ^an   Mack, Wendy J ^k   Marson, Daniel C ^bh   Martin, Eden R ^am   Martiniuk, Frank ^cd   Mash, Deborah C ^am   McCormick, Wayne C ^ae   McCurry, Susan M ^af   McDavid, Andrew N ^bd   McKee, Ann C ^ao   Mesulam, Marsel ^ce   Miller, Bruce L ^c,ay   Miller, Carol A ^k   Miller, Joshua W ^e   Montine, Thomas J ^af   Morris, John C ^bb   Myers, Amanda J ^cf   Naj, Adam C ^am   Nowotny, Petra ^bb   Parisi, Joseph E ^aw   Perl, Daniel P ^ba   Peskind, Elaine ^ae   Poon, Wayne W ^bj   Potter, Huntington ^bc   Quinn, Joseph F ^bz   Raj, Ashok ^bc   Rajbhandary, Ruchita A ^am   Raskind, Murray ^ae   Reiman, Eric M ^bi,cg,ch,ci   Reisberg, Barry ^bq,cd   Reitz, Christiane ^z,cj   Roberson, Erik D ^bh   Rogaeva, Ekaterina ^ck   Rosenberg, Roger N ^ai   Sano, Mary ^ba   Saykin, Andrew J ^bp   Schneider, Julie A ^as   Schneider, Lon S ^k   Seeley, William ^ay   Shelanski, Michael L ^z   Slifer, Michael A ^am   Smith, Charles D ^bx   Sonnen, Joshua A ^af   George Hyslop, Peter St ^ck,cl   Stern, Robert A ^ao   Tanzi, Rudolph E ^av   Trojanowski, John Q ^g   Tsuang, Debby W ^ae   Vardarajan, Badri Narayan ^ao   Vinters, Harry V ^a   Paul Vonsattel, Jean ^z   Weintraub, Sandra ^ce   Welsh Bohmer, Kathleen A ^az   Williamson, Jennifer ^z   Woltjer, Randall L ^bz   Younkin, Steven G ^bf   Ross, Owen A ^h   Rademakers, Rosa ^h   Schellenberg, Gerard D ^g   Mandelkow, Eckhard ^f   Geschwind, Daniel H ^a,b,bt   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h MAYO CLINIC   (United States)

ⁱ NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^j EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^l UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^m INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

ⁿ Department of Neurology   (France)

^o PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^p KING'S COLLEGE LONDON   (United Kingdom)

^q MAYO CLINIC ROCHESTER   (United States)

^r DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^s NORTHWESTERN UNIVERSITY   (United States)

^t UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^u UNIVERSITY OF WESTERN ONTARIO   (Canada)

^v MAYO CLINIC   (United States)

^w INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^x VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^y HARVARD MEDICAL SCHOOL   (United States)

^z Och Spine at New York Presbyterian Hospitals   (United States)

^aa NewYork Presbyterian Hospital   (United States)

^ab SUN HEALTH RESEARCH INSTITUTE   (United States)

^ac UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^ad VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^ae UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^af UNIVERSITY OF WASHINGTON   (United States)

^ag UNIVERSITY OF CALIFORNIA   (United States)

^ah UNIVERSITY OF CALIFORNIA   (United States)

^ai UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^aj JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^ak HÔPITAL CHARLES NICOLLE   (France)

^al VANDERBILT UNIVERSITY   (United States)

^am UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^an BOSTON UNIVERSITY   (United States)

^ao BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^ap BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^aq UNIVERSITY OF TEXAS AT ARLINGTON   (United States)

^ar UNIVERSITY OF PITTSBURGH   (United States)

^as RUSH UNIVERSITY MEDICAL CENTER   (United States)

^at RUSH UNIVERSITY MEDICAL CENTER   (United States)

^au HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^av MASSACHUSETTS GENERAL HOSPITAL   (United States)

^aw MAYO CLINIC   (United States)

^ax SWEDISH MEDICAL CENTER   (United States)

^ay UNIVERSITY OF CALIFORNIA   (United States)

^az DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^ba MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^bb WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bc UNIVERSITY OF SOUTH FLORIDA   (United States)

^bd Fred Hutchinson Cancer Research Center   (United States)

^be VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^bf MAYO GRADUATE SCHOOL   (United States)

^bg University of Alabama at Birmingham   (United States)

^bh The University of Alabama at Birmingham   (United States)

^bi TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^bj UNIVERSITY OF CALIFORNIA   (United States)

^bk BRIGHAM AND WOMEN S HOSPITAL   (United States)

^bl BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^bm UNIVERSITY OF VIRGINIA   (United States)

^bn MOUNT SINAI MEDICAL CENTER   (United States)

^bo RUSH UNIVERSITY MEDICAL CENTER   (United States)

^bp INDIANA UNIVERSITY   (United States)

^bq NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^br UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^bs EMORY UNIVERSITY   (United States)

^bt UNIVERSITY OF CALIFORNIA   (United States)

^bu UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^bv CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^bw UNIVERSITY COLLEGE LONDON   (United Kingdom)

^bx UNIVERSITY OF KENTUCKY   (United States)

^by BRIGHAM YOUNG UNIVERSITY   (United States)

^bz OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^ca Oregon Health and Science University Department of Biomedical Engineering   (United States)

^cb OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^cc GROUP HEALTH RESEARCH INSTITUTE   (United States)

^cd NEW YORK UNIVERSITY   (United States)

^ce NORTHWESTERN UNIVERSITY   (United States)

^cf FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^cg UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^ch ARIZONA ALZHEIMER S CONSORTIUM   (United States)

^ci BANNER ALZHEIMER S INSTITUTE   (United States)

^cj Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^ck UNIVERSITY OF TORONTO   (Canada)

^cl UNIVERSITY OF CAMBRIDGE   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

OLIGOMER; PROTEIN VARIANT; TAU PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CAUCASIAN; CELL AGGREGATION; CELL FUNCTION; CELL INTERACTION; CONTROLLED STUDY; FEMALE; FOLLOW UP; FRONTOTEMPORAL DEMENTIA; GENE FREQUENCY; GENE LOCUS; GENE MUTATION; GENETIC CODE; GENETIC RISK; GENETIC SCREENING; GENETIC VARIABILITY; HAPLOTYPE; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROTUBULE; MICROTUBULE ASSEMBLY; ONSET AGE; PROGRESSIVE SUPRANUCLEAR PALSY; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RISK FACTOR; TAUOPATHY;

EID: 84864505483     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds161     Document Type: Article

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