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Volumn 4, Issue , 2014, Pages

Higher omega-3 index is associated with increased insulin sensitivity and more favourable metabolic profile in middle-aged overweight men

Author keywords

[No Author keywords available]

Indexed keywords

OMEGA 3 FATTY ACID;

EID: 84937508470     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep06697     Document Type: Article
Times cited : (82)

References (63)
  • 1
    • 0026021161 scopus 로고
    • Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
    • De Fronzo, R. A. & Ferrannini, E. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14, 173-194 (1991).
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • De Fronzo, R.A.1    Ferrannini, E.2
  • 2
    • 79751531393 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2011 update: A report from the American Heart Association
    • Roger, V. L. et al. Heart disease and stroke statistics-2011 update: a report from the American Heart Association. Circulation 123, e18-e209, doi:10.1161/CIR.0b013e3182009701 (2011).
    • (2011) Circulation , vol.123 , pp. e18-e209
    • Roger, V.L.1
  • 3
    • 0142244847 scopus 로고    scopus 로고
    • Risk factors for chronic kidney disease: A prospective study of 23,534 men and women in Washington County, Maryland
    • Haroun, M. K. et al. Risk factors for chronic kidney disease: a prospective study of 23,534 men and women in Washington County, Maryland. J. Am. Soc. Nephrol. 14, 2934-2941 (2003).
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 2934-2941
    • Haroun, M.K.1
  • 4
    • 0037314210 scopus 로고    scopus 로고
    • Risk factors for incident retinopathy in a diabetic and nondiabetic population: The Hoorn study
    • van Leiden, H. A. et al. Risk factors for incident retinopathy in a diabetic and nondiabetic population: the Hoorn study. Arch. Ophthalmol. 121, 245-251 (2003).
    • (2003) Arch. Ophthalmol. , vol.121 , pp. 245-251
    • Van Leiden, H.A.1
  • 5
    • 84863666187 scopus 로고    scopus 로고
    • Insulin resistance and cancer risk: An overview of the pathogenetic mechanisms
    • Arcidiacono, B. et al. Insulin resistance and cancer risk: an overview of the pathogenetic mechanisms. Exp. Diabetes Res. 2012, 789174 (2012).
    • (2012) Exp. Diabetes Res. , vol.2012 , pp. 789174
    • Arcidiacono, B.1
  • 6
    • 0033054725 scopus 로고    scopus 로고
    • Effects of weight loss on regional fat distribution and insulin sensitivity in obesity
    • Goodpaster, B. H., Kelley, D. E., Wing, R. R., Meier, A. & Thaete, F. L. Effects of weight loss on regional fat distribution and insulin sensitivity in obesity. Diabetes 48, 839-847, doi:10.2337/diabetes.48.4.839 (1999).
    • (1999) Diabetes , vol.48 , pp. 839-847
    • Goodpaster, B.H.1    Kelley, D.E.2    Wing, R.R.3    Meier, A.4    Thaete, F.L.5
  • 7
    • 39149131036 scopus 로고    scopus 로고
    • Improved insulin sensitivity and adiponectin level after exercise training in obese Korean youth
    • Kim, E. S. et al. Improved insulin sensitivity and adiponectin level after exercise training in obese Korean youth. Obesity 15, 3023-3030, doi:10.1038/oby.2007.360 (2007).
    • (2007) Obesity , vol.15 , pp. 3023-3030
    • Kim, E.S.1
  • 8
    • 79960884946 scopus 로고    scopus 로고
    • Fish, shellfish, and long-chain n23 fatty acid consumption and risk of incident type 2 diabetes in middle-aged Chinese men and women
    • Villegas, R. et al. Fish, shellfish, and long-chain n23 fatty acid consumption and risk of incident type 2 diabetes in middle-aged Chinese men and women. Am. J. Clin. Nutr. 94, 543-551, doi:10.3945/ajcn.111.013193 (2011).
    • (2011) Am. J. Clin. Nutr. , vol.94 , pp. 543-551
    • Villegas, R.1
  • 9
    • 79960867594 scopus 로고    scopus 로고
    • Plasma omega-3 fatty acids and incident diabetes in older adults
    • Djoussé, L. et al. Plasma omega-3 fatty acids and incident diabetes in older adults. Am. J. Clin. Nutr. 94, 527-533, doi:10.3945/ajcn.111.013334 (2011).
    • (2011) Am. J. Clin. Nutr. , vol.94 , pp. 527-533
    • Djoussé, L.1
  • 10
    • 84892419206 scopus 로고    scopus 로고
    • Serum omega-3 polyunsaturated fatty acids and risk of incident type 2 diabetes in men: The Kuopio Ischemic Heart Disease Risk Factor study
    • Virtanen, J. K., Mursu, J., Voutilainen, S., Uusitupa, M. & Tuomainen, T. P. Serum omega-3 polyunsaturated fatty acids and risk of incident type 2 diabetes in men: the Kuopio Ischemic Heart Disease Risk Factor study. Diabetes Care 37, 189-196, doi:10.2337/dc13-1504 (2014).
    • (2014) Diabetes Care , vol.37 , pp. 189-196
    • Virtanen, J.K.1    Mursu, J.2    Voutilainen, S.3    Uusitupa, M.4    Tuomainen, T.P.5
  • 11
    • 77956165390 scopus 로고    scopus 로고
    • GPR120 is an omega-3 fatty acid receptor mediating potent antiinflammatory and insulin-sensitizing effects
    • Oh, D. Y. et al. GPR120 is an omega-3 fatty acid receptor mediating potent antiinflammatory and insulin-sensitizing effects. Cell 142, 687-698, doi:10.1016/j.cell.2010.07.041 (2010).
    • (2010) Cell , vol.142 , pp. 687-698
    • Oh, D.Y.1
  • 12
    • 33745222339 scopus 로고    scopus 로고
    • Defining high-fat-diet rat models: Metabolic and molecular effects of different fat types
    • Buettner, R. et al. Defining high-fat-diet rat models: metabolic and molecular effects of different fat types. J. Mol. Endocrinol. 36, 485-501 (2006).
    • (2006) J. Mol. Endocrinol. , vol.36 , pp. 485-501
    • Buettner, R.1
  • 13
    • 31544471650 scopus 로고    scopus 로고
    • Dietary (n-3) long chain polyunsaturated fatty acids prevent sucrose-induced insulin resistance in rats
    • Ghafoorunissa, I. A., Rajkumar, L. & Acharya, V. Dietary (n-3) long chain polyunsaturated fatty acids prevent sucrose-induced insulin resistance in rats. J. Nutr. 135, 2634-2638 (2005).
    • (2005) J. Nutr. , vol.135 , pp. 2634-2638
    • Ghafoorunissa, I.A.1    Rajkumar, L.2    Acharya, V.3
  • 14
    • 82255179405 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acid and insulin sensitivity: A meta-analysis of randomized controlled trials
    • Akinkuolie, A. O., Ngwa, J. S., Meigs, J. B. & Djousse, L. Omega-3 polyunsaturated fatty acid and insulin sensitivity: a meta-analysis of randomized controlled trials. Clin. Nutr. 30, 702-707, doi:10.1016/j.clnu.2011.08.013 (2011).
    • (2011) Clin. Nutr. , vol.30 , pp. 702-707
    • Akinkuolie, A.O.1    Ngwa, J.S.2    Meigs, J.B.3    Djousse, L.4
  • 15
    • 82855171050 scopus 로고    scopus 로고
    • Supplementation of n3 long-chain polyunsaturated fatty acid synergistically decreases insulin resistance with weight loss of obese prepubertal and pubertal children
    • López-Alarcón, M., Martínez-Coronado, A., Velarde-Castro, O., Rendón-Macías, E. & Fernández, J. Supplementation of n3 long-chain polyunsaturated fatty acid synergistically decreases insulin resistance with weight loss of obese prepubertal and pubertal children. Arch. Med. Res. 42, 502-508 (2011).
    • (2011) Arch. Med. Res. , vol.42 , pp. 502-508
    • López-Alarcón, M.1    Martínez-Coronado, A.2    Velarde-Castro, O.3    Rendón-Macías, E.4    Fernández, J.5
  • 16
    • 44649201088 scopus 로고    scopus 로고
    • Beneficial effects of long-chain n-3 fatty acids included in an energy-restricted diet on insulin resistance in overweight and obese European young adults
    • Ramel, A. et al. Beneficial effects of long-chain n-3 fatty acids included in an energy-restricted diet on insulin resistance in overweight and obese European young adults. Diabetologia 51, 1261-1268, doi:10.1007/s00125-008-1035-7 (2008).
    • (2008) Diabetologia , vol.51 , pp. 1261-1268
    • Ramel, A.1
  • 17
    • 0032692793 scopus 로고    scopus 로고
    • Dietary fish as amajor component of a weight-loss diet: Effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects
    • Mori, T. A. et al. Dietary fish as amajor component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects. Am. J. Clin. Nutr. 70, 817-825 (1999).
    • (1999) Am. J. Clin. Nutr. , vol.70 , pp. 817-825
    • Mori, T.A.1
  • 18
    • 4544288392 scopus 로고    scopus 로고
    • Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome
    • Esposito, K. et al. Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome. JAMA 292, 1440-1446 (2004).
    • (2004) JAMA , vol.292 , pp. 1440-1446
    • Esposito, K.1
  • 19
    • 43249090355 scopus 로고    scopus 로고
    • High omega-3 fat intake improves insulin sensitivity and reduces CRP and IL6, but does not affect other endocrine axes in healthy older adults
    • Tsitouras, P., Gucciardo, F., Salbe, A., Heward, C. & Harman, S. High omega-3 fat intake improves insulin sensitivity and reduces CRP and IL6, but does not affect other endocrine axes in healthy older adults. Horm. Metab. Res. 40, 199-205 (2008).
    • (2008) Horm. Metab. Res. , vol.40 , pp. 199-205
    • Tsitouras, P.1    Gucciardo, F.2    Salbe, A.3    Heward, C.4    Harman, S.5
  • 20
    • 0035081372 scopus 로고    scopus 로고
    • Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study
    • Vessby, B. et al. Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study. Diabetologia 44, 312-319 (2001).
    • (2001) Diabetologia , vol.44 , pp. 312-319
    • Vessby, B.1
  • 21
    • 2942724415 scopus 로고    scopus 로고
    • The Omega-3 index: A new risk factor for death from coronary heart disease?
    • Harris, W. S. & Von Schacky, C. The Omega-3 Index: a new risk factor for death from coronary heart disease? Prev. Med. 39, 212-220, doi:10.1016/j.ypmed.2004.02.030 (2004).
    • (2004) Prev. Med. , vol.39 , pp. 212-220
    • Harris, W.S.1    Von Schacky, C.2
  • 22
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
    • Matsuda, M. & De Fronzo, R. A. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22, 1462-1470 (1999).
    • (1999) Diabetes Care , vol.22 , pp. 1462-1470
    • Matsuda, M.1    De Fronzo, R.A.2
  • 23
    • 78049519084 scopus 로고    scopus 로고
    • Relation of direct and surrogate measures of insulin resistance to cardiovascular risk factors in nondiabetic Finnish offspring of type 2 diabetic individuals
    • Lorenzo, C., Haffner, S. M., Stancakova, A. & Laakso, M. Relation of direct and surrogate measures of insulin resistance to cardiovascular risk factors in nondiabetic Finnish offspring of type 2 diabetic individuals. J. Clin. Endocrinol. Metab. 95, 5082-5090 (2010).
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 5082-5090
    • Lorenzo, C.1    Haffner, S.M.2    Stancakova, A.3    Laakso, M.4
  • 24
    • 78649388428 scopus 로고    scopus 로고
    • Repeatability of indices of insulin sensitivity and secretion from standard liquid meal tests in subjects with type 2 diabetes mellitus or normal or impaired fasting glucose
    • Maki, K. C., Rains, T. M., Dicklin, M. R. & Bell, M. Repeatability of indices of insulin sensitivity and secretion from standard liquid meal tests in subjects with type 2 diabetes mellitus or normal or impaired fasting glucose. Diabetes Technol. Ther. 12, 895-900 (2010).
    • (2010) Diabetes Technol. Ther. , vol.12 , pp. 895-900
    • Maki, K.C.1    Rains, T.M.2    Dicklin, M.R.3    Bell, M.4
  • 25
    • 0027375768 scopus 로고
    • Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function
    • Kahn, S. et al. Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes 42, 1663-1672 (1993).
    • (1993) Diabetes , vol.42 , pp. 1663-1672
    • Kahn, S.1
  • 26
    • 36849067841 scopus 로고    scopus 로고
    • Comparison of the effects of fish and fish-oil capsules on the n-3 fatty acid content of blood cells and plasma phospholipids
    • Harris, W. S., Pottala, J. V., Sands, S. A. & Jones, P. G. Comparison of the effects of fish and fish-oil capsules on the n-3 fatty acid content of blood cells and plasma phospholipids. Am. J. Clin. Nutr. 86, 1621-1625 (2007).
    • (2007) Am. J. Clin. Nutr. , vol.86 , pp. 1621-1625
    • Harris, W.S.1    Pottala, J.V.2    Sands, S.A.3    Jones, P.G.4
  • 27
    • 0030711745 scopus 로고    scopus 로고
    • Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: An 18-month controlled study
    • Katan, M. B., Deslypere, J. P., van Birgelen, A. P., Penders, M. & Zegwaard, M. Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: an 18-month controlled study. J. Lipid Res. 38, 2012-2022 (1997).
    • (1997) J. Lipid Res. , vol.38 , pp. 2012-2022
    • Katan, M.B.1    Deslypere, J.P.2    Van Birgelen, A.P.3    Penders, M.4    Zegwaard, M.5
  • 28
    • 0008568930 scopus 로고    scopus 로고
    • Use and interpretation of ambulatory blood pressure monitoring: Recommendations of the British Hypertension Society
    • O'Brien, E. et al. Use and interpretation of ambulatory blood pressure monitoring: recommendations of the British Hypertension Society. BMJ 320, 1128-1134 (2000).
    • (2000) BMJ , vol.320 , pp. 1128-1134
    • O'Brien, E.1
  • 30
    • 50449097768 scopus 로고    scopus 로고
    • A practical protocol to measure common carotid artery intimamedia thickness
    • Casella, I. B. et al. A practical protocol to measure common carotid artery intimamedia thickness. Clinics 63, 515-520 (2008).
    • (2008) Clinics , vol.63 , pp. 515-520
    • Casella, I.B.1
  • 31
    • 33846850165 scopus 로고    scopus 로고
    • The International Physical Activity Questionnaire (IPAQ): A study of concurrent and construct validity
    • Hagstromer, M., Oja, P. & Sjostrom, M. The International Physical Activity Questionnaire (IPAQ): a study of concurrent and construct validity. Public Health Nutr. 9, 755-762 (2006).
    • (2006) Public Health Nutr. , vol.9 , pp. 755-762
    • Hagstromer, M.1    Oja, P.2    Sjostrom, M.3
  • 33
    • 0022548964 scopus 로고
    • Direct transesterification of all classes of lipids in a one-step reaction
    • Lepage, G. & Roy, C. Direct transesterification of all classes of lipids in a one-step reaction. J. Lipid Res. 27, 114-120 (1986).
    • (1986) J. Lipid Res. , vol.27 , pp. 114-120
    • Lepage, G.1    Roy, C.2
  • 34
    • 84874725861 scopus 로고    scopus 로고
    • Collinearity: A review of methods to deal with it and a simulation study evaluating their performance
    • Dormann, C. F. et al. Collinearity: a review of methods to deal with it and a simulation study evaluating their performance. Ecography 36, 027-046 (2013).
    • (2013) Ecography , vol.36 , pp. 027-046
    • Dormann, C.F.1
  • 35
    • 79960125209 scopus 로고    scopus 로고
    • Omega-3 index, obesity and insulin resistance in children
    • Burrows, T., Collins, C. E. & Garg, M. L. Omega-3 index, obesity and insulin resistance in children. Int. J. Pediatr. Obes. 6, e532-539, doi:10.3109/17477166.2010.549489 (2011).
    • (2011) Int. J. Pediatr. Obes. , vol.6 , pp. e532-539
    • Burrows, T.1    Collins, C.E.2    Garg, M.L.3
  • 36
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and b-cell dysfunction
    • Boden, G. & Shulman, G. I. Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and b-cell dysfunction. Eur. J. Clin. Invest. 32, 14-23, doi:10.1046/j.1365-2362.32.s3.3.x (2002).
    • (2002) Eur. J. Clin. Invest. , vol.32 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 37
    • 58049219012 scopus 로고    scopus 로고
    • Adipose tissue dysfunction in obesity, diabetes, and vascular diseases
    • Hajer, G. R., van Haeften, T. W. & Visseren, F. L. J. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. Eur. Heart J. 29, 2959-2971, doi:10.1093/eurheartj/ehn387 (2008).
    • (2008) Eur. Heart J. , vol.29 , pp. 2959-2971
    • Hajer, G.R.1    Van Haeften, T.W.2    Visseren, F.L.J.3
  • 38
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu, H. et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112, 1821-1830 (2003).
    • (2003) J. Clin. Invest. , vol.112 , pp. 1821-1830
    • Xu, H.1
  • 39
    • 0345275811 scopus 로고    scopus 로고
    • Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects
    • Tripathy, D. et al. Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects. Diabetes 52, 2882-2887 (2003).
    • (2003) Diabetes , vol.52 , pp. 2882-2887
    • Tripathy, D.1
  • 40
    • 34047166373 scopus 로고    scopus 로고
    • N-3 fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-α-dependent manner
    • Neschen, S. et al. n-3 fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-α-dependent manner. Diabetes 56, 1034-1041, doi:10.2337/db06-1206 (2007).
    • (2007) Diabetes , vol.56 , pp. 1034-1041
    • Neschen, S.1
  • 41
    • 84655174598 scopus 로고    scopus 로고
    • (n-3) Fatty acids alleviate adipose tissue inflammation and insulin resistance: Mechanistic insights
    • Kalupahana, N. S., Claycombe, K. J. & Moustaid-Moussa, N. (n-3) fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights. Adv. Nutr. 2, 304-316, doi:10.3945/an.111.000505 (2011).
    • (2011) Adv. Nutr. , vol.2 , pp. 304-316
    • Kalupahana, N.S.1    Claycombe, K.J.2    Moustaid-Moussa, N.3
  • 42
    • 33751181461 scopus 로고    scopus 로고
    • Pioglitazone increases secretion of high-molecular-weight adiponectin from adipocytes
    • Bodles, A. M. et al. Pioglitazone increases secretion of high-molecular-weight adiponectin from adipocytes. Am. J. Physiol. Endocrinol. Metab. 291, E1100-E1105 (2006).
    • (2006) Am. J. Physiol. Endocrinol. Metab. , vol.291 , pp. E1100-E1105
    • Bodles, A.M.1
  • 43
    • 0033659881 scopus 로고    scopus 로고
    • Unraveling the mechanism of action of thiazolidinediones
    • Kahn, C. R., Chen, L. & Cohen, S. E. Unraveling the mechanism of action of thiazolidinediones. J. Clin. Invest. 106, 1305-1307, doi:10.1172/jci11705 (2000).
    • (2000) J. Clin. Invest. , vol.106 , pp. 1305-1307
    • Kahn, C.R.1    Chen, L.2    Cohen, S.E.3
  • 44
    • 84860575447 scopus 로고    scopus 로고
    • Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs
    • Im, D. S. Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs. Prog. Lipid Res. 51, 232-237, doi:10.1016/j.plipres.2012.02.003 (2012).
    • (2012) Prog. Lipid Res. , vol.51 , pp. 232-237
    • Im, D.S.1
  • 45
    • 67349173942 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale
    • Calder, P. C. Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale. Biochimie 91, 791-795, doi:10.1016/j.biochi.2009.01.008 (2009).
    • (2009) Biochimie , vol.91 , pp. 791-795
    • Calder, P.C.1
  • 46
    • 84864219466 scopus 로고    scopus 로고
    • N-3 fatty acids and cardiovascular outcomes in patients with dysglycaemia
    • ORIGIN Trial Investigators et al. n-3 fatty acids and cardiovascular outcomes in patients with dysglycaemia. N. Engl. J. Med. 367, 309-318 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , pp. 309-318
  • 47
    • 0033851158 scopus 로고    scopus 로고
    • Fish oil supplementation in type 2 diabetes: A quantitative systematic review
    • Montori, V. M., Farmer, A., Wollan, P. C. & Dinneen, S. F. Fish oil supplementation in type 2 diabetes: a quantitative systematic review. Diabetes Care 23, 1407-1415 (2000).
    • (2000) Diabetes Care , vol.23 , pp. 1407-1415
    • Montori, V.M.1    Farmer, A.2    Wollan, P.C.3    Dinneen, S.F.4
  • 48
    • 44949173089 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids (PUFA) for type 2 diabetes mellitus
    • Hartweg, J. et al. Omega-3 polyunsaturated fatty acids (PUFA) for type 2 diabetes mellitus. Cochrane Database Syst. Rev. 1, CD003205 (2008).
    • (2008) Cochrane Database Syst. Rev. , vol.1 , pp. CD003205
    • Hartweg, J.1
  • 49
    • 61849106040 scopus 로고    scopus 로고
    • Oral disposition index predicts the development of future diabetes above and beyond fasting and 2-h glucose levels
    • Utzschneider, K. M. et al. Oral disposition index predicts the development of future diabetes above and beyond fasting and 2-h glucose levels. Diabetes Care 32, 335-341 (2009).
    • (2009) Diabetes Care , vol.32 , pp. 335-341
    • Utzschneider, K.M.1
  • 50
    • 80955180014 scopus 로고    scopus 로고
    • Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders
    • Hara, T., Hirasawa, A., Ichimura, A., Kimura, I. & Tsujimoto, G. Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders. J. Pharm. Sci. 100, 3594-3601 (2011).
    • (2011) J. Pharm. Sci. , vol.100 , pp. 3594-3601
    • Hara, T.1    Hirasawa, A.2    Ichimura, A.3    Kimura, I.4    Tsujimoto, G.5
  • 51
    • 0037434991 scopus 로고    scopus 로고
    • Free fatty acids regulate insulin secretion from pancreatic b-cells through GPR40
    • Itoh, Y. et al. Free fatty acids regulate insulin secretion from pancreatic b-cells through GPR40. Nature 422, 173-176 (2003).
    • (2003) Nature , vol.422 , pp. 173-176
    • Itoh, Y.1
  • 52
    • 70349988797 scopus 로고    scopus 로고
    • G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell
    • Morgan, N. G. & Dhayal, S. G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell. Biochem. Pharmacol. 78, 1419-1427 (2009).
    • (2009) Biochem. Pharmacol. , vol.78 , pp. 1419-1427
    • Morgan, N.G.1    Dhayal, S.2
  • 53
    • 0036853641 scopus 로고    scopus 로고
    • Prognostic significance of the nocturnal decline in blood pressure in individuals with and without high 24-h blood pressure: The Ohasama study
    • Ohkubo, T. et al. Prognostic significance of the nocturnal decline in blood pressure in individuals with and without high 24-h blood pressure: the Ohasama study. J. Hypertens. 20, 2183-2189 (2002).
    • (2002) J. Hypertens. , vol.20 , pp. 2183-2189
    • Ohkubo, T.1
  • 54
    • 0036668195 scopus 로고    scopus 로고
    • Blood pressure response to fish oil supplementation: Metaregression analysis of randomized trials
    • Geleijnse, J. M., Giltay, E. J., Grobbee, D. E., Donders, A. R. T. & Kok, F. J. Blood pressure response to fish oil supplementation: metaregression analysis of randomized trials. J. Hypertens. 20, 1493-1499 (2002).
    • (2002) J. Hypertens. , vol.20 , pp. 1493-1499
    • Geleijnse, J.M.1    Giltay, E.J.2    Grobbee, D.E.3    Donders, A.R.T.4    Kok, F.J.5
  • 55
    • 0037061915 scopus 로고    scopus 로고
    • Blood levels of long-chain n-3 fatty acids and the risk of sudden death
    • Albert, C. M. et al. Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N. Engl. J. Med. 346, 1113-1118, doi:10.1056/NEJMoa012918 (2002).
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1113-1118
    • Albert, C.M.1
  • 56
    • 0024532492 scopus 로고
    • Insulin secretion and insulin action related to the serum phospholipid fatty acid pattern in healthy men
    • Pelikánová, T., Kohout, M., Válek, J. í., Baše, J. í. & Kazdová, L. Insulin secretion and insulin action related to the serum phospholipid fatty acid pattern in healthy men. Metabolism. 38, 188-192 (1989).
    • (1989) Metabolism , vol.38 , pp. 188-192
    • Pelikánová, T.1    Kohout, M.2    Válek, J.I.3    Baše J.I..4    Kazdová, L.5
  • 57
    • 0027395358 scopus 로고
    • The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids
    • Borkman, M. et al. The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. N. Engl. J. Med. 328, 238-244 (1993).
    • (1993) N. Engl. J. Med. , vol.328 , pp. 238-244
    • Borkman, M.1
  • 58
    • 0028071690 scopus 로고
    • Insulin sensitivity is related to the fatty acid composition of serum lipids and skeletal muscle phospholipids in 70-year-old men
    • Vessby, B., Tengblad, S. & Lithell, H. Insulin sensitivity is related to the fatty acid composition of serum lipids and skeletal muscle phospholipids in 70-year-old men. Diabetologia 37, 1044-1050, doi:10.1007/bf00400468 (1994).
    • (1994) Diabetologia , vol.37 , pp. 1044-1050
    • Vessby, B.1    Tengblad, S.2    Lithell, H.3
  • 59
    • 0029087640 scopus 로고
    • Relationships of generalized and regional adiposity to insulin sensitivity in men
    • Abate, N., Garg, A., Peshock, R. M., Stray-Gundersen, J. & Grundy, S. M. Relationships of generalized and regional adiposity to insulin sensitivity in men. J. Clin. Invest. 96, 88-98, doi:10.1172/jci118083 (1995).
    • (1995) J. Clin. Invest. , vol.96 , pp. 88-98
    • Abate, N.1    Garg, A.2    Peshock, R.M.3    Stray-Gundersen, J.4    Grundy, S.M.5
  • 60
    • 73349085284 scopus 로고    scopus 로고
    • Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity
    • Micallef, M., Munro, I., Phang, M. & Garg, M. Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity. Br. J. Nutr. 102, 1370-1374, doi:10.1017/s0007114509382173 (2009).
    • (2009) Br. J. Nutr. , vol.102 , pp. 1370-1374
    • Micallef, M.1    Munro, I.2    Phang, M.3    Garg, M.4
  • 61
    • 79960125209 scopus 로고    scopus 로고
    • Omega-3 index, obesity and insulin resistance in children
    • Burrows, T., Collins, C. E. & Garg, M. L. Omega-3 index, obesity and insulin resistance in children. Int. J. Pediatr. Obes. 6, e532-e539, doi:doi:10.3109/17477166.2010.549489 (2011).
    • (2011) Int. J. Pediatr. Obes. , vol.6 , pp. e532-e539
    • Burrows, T.1    Collins, C.E.2    Garg, M.L.3
  • 62
    • 84950170977 scopus 로고    scopus 로고
    • Anti-obesity effects of long-chain omega-3 polyunsaturated fatty acids
    • Buckley, J. D. & Howe, P. R. Anti-obesity effects of long-chain omega-3 polyunsaturated fatty acids. Obes. Rev. 10, 648-659, doi:10.1111/j.1467-789X.2009.00584.x (2009).
    • (2009) Obes. Rev. , vol.10 , pp. 648-659
    • Buckley, J.D.1    Howe, P.R.2
  • 63
    • 84904424681 scopus 로고    scopus 로고
    • Fish or n3-PUFA intake and body composition: A systematic review and meta-analysis
    • Bender, N. et al. Fish or n3-PUFA intake and body composition: a systematic review and meta-analysis. Obes. Rev. 15, 657-665, doi:10.1111/obr.12189 (2014).
    • (2014) Obes. Rev. , vol.15 , pp. 657-665
    • Bender, N.1


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