Coordinated regulation of the neutral amino acid transporter SNAT2 and the protein phosphatase subunit GADD34 promotes adaptation to increased extracellular osmolarity

Journal of Biological Chemistry

Volumn 290, Issue 29, 2015, Pages 17822-17837

  Krokowski, Dawid ^a   Jobava, Raul ^a   Guan, Bo Jhih ^a   Farabaugh, Kenneth ^a   Wu, Jing ^a   Majumder, Mithu ^a   Bianchi, Massimiliano G ^b   Snider, Martin D ^a   Bussolati, Ovidio ^b   Hatzoglou, Maria ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PARMA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL DEATH; GENES; PHOSPHATASES; PHOSPHORYLATION; PROTEINS;

ACTIVATING TRANSCRIPTION FACTOR; AMINO ACID TRANSPORTER; CAMP-RESPONSE ELEMENTS; EXTRACELLULAR OSMOLARITY; HYPEROSMOTIC STRESS; POST-TRANSCRIPTIONAL; PROTEIN PHOSPHATASE-1; TRANSCRIPTIONAL CONTROL;

TRANSCRIPTION;

ACTIVATING TRANSCRIPTION FACTOR 2; ACTIVATING TRANSCRIPTION FACTOR 3; ACTIVATING TRANSCRIPTION FACTOR 4; AMINO ACID TRANSPORTER; CYCLIC AMP; INITIATION FACTOR 2ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN C JUN; PROTEIN GADD34; PROTEIN SNAT2; STRESS ACTIVATED PROTEIN KINASE 1; TUBULIN; UNCLASSIFIED DRUG; INITIATION FACTOR 2; PPP1R15A PROTEIN, HUMAN; PPP1R15A PROTEIN, MOUSE; SLC38A2 PROTEIN, HUMAN; SLC38A2 PROTEIN, MOUSE;

ADAPTATION; AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; EXTRACELLULAR SPACE; GADD34 GENE; GENE; HYPEROSMOTIC STRESS; MOUSE; NONHUMAN; OSMOLARITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; METABOLISM; OSMOTIC PRESSURE; PHOSPHORYLATION;

AMINO ACID TRANSPORT SYSTEM A; ANIMALS; CELL LINE; CELL SURVIVAL; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; HEK293 CELLS; HELA CELLS; HUMANS; MICE; OSMOTIC PRESSURE; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN PHOSPHATASE 1;

EID: 84937458769     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.636217     Document Type: Article

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