-
1
-
-
77952786601
-
EIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress
-
E. Bevilacqua, X. Wang, M. Majumder, F. Gaccioli, C.L. Yuan, C. Wang, and et al. eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress J Biol Chem 285 2010 17098 17111
-
(2010)
J Biol Chem
, vol.285
, pp. 17098-17111
-
-
Bevilacqua, E.1
Wang, X.2
Majumder, M.3
Gaccioli, F.4
Yuan, C.L.5
Wang, C.6
-
3
-
-
0035231288
-
Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis
-
M.J. Clemens Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis Prog Mol Subcell Biol 27 2001 57 89
-
(2001)
Prog Mol Subcell Biol
, vol.27
, pp. 57-89
-
-
Clemens, M.J.1
-
4
-
-
79955656979
-
The structure of the PERK kinase domain suggests the mechanism for its activation
-
W. Cui, J. Li, D. Ron, and B. Sha The structure of the PERK kinase domain suggests the mechanism for its activation Acta Crystallogr, D Biol Crystallogr 67 2011 423 428
-
(2011)
Acta Crystallogr, D Biol Crystallogr
, vol.67
, pp. 423-428
-
-
Cui, W.1
Li, J.2
Ron, D.3
Sha, B.4
-
5
-
-
25144502820
-
Higher-order substrate recognition of eIF2alpha by the RNA-dependent protein kinase PKR
-
A.C. Dar, T.E. Dever, and F. Sicheri Higher-order substrate recognition of eIF2alpha by the RNA-dependent protein kinase PKR Cell 122 2005 887 900
-
(2005)
Cell
, vol.122
, pp. 887-900
-
-
Dar, A.C.1
Dever, T.E.2
Sicheri, F.3
-
6
-
-
0037031145
-
Activation of GCN2 in UV-irradiated cells inhibits translation
-
J. Deng, H.P. Harding, B. Raught, A.C. Gingras, J.J. Berlanga, D. Scheuner, and et al. Activation of GCN2 in UV-irradiated cells inhibits translation Curr Biol 12 2002 1279 1286
-
(2002)
Curr Biol
, vol.12
, pp. 1279-1286
-
-
Deng, J.1
Harding, H.P.2
Raught, B.3
Gingras, A.C.4
Berlanga, J.J.5
Scheuner, D.6
-
7
-
-
20144386673
-
PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha
-
M. Dey, B. Trieselmann, E.G. Locke, J. Lu, C. Cao, A.C. Dar, and et al. PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha Mol Cell Biol 25 2005 3063 75
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3063-3075
-
-
Dey, M.1
Trieselmann, B.2
Locke, E.G.3
Lu, J.4
Cao, C.5
Dar, A.C.6
-
8
-
-
0242321013
-
The crystal structure of the N-terminal region of the alpha subunit of translation initiation factor 2 (eIF2alpha) from Saccharomyces cerevisiae provides a view of the loop containing serine 51, the target of the eIF2alpha-specific kinases
-
S. Dhaliwal, and D.W. Hoffman The crystal structure of the N-terminal region of the alpha subunit of translation initiation factor 2 (eIF2alpha) from Saccharomyces cerevisiae provides a view of the loop containing serine 51, the target of the eIF2alpha-specific kinases J Mol Biol 334 2003 187 195
-
(2003)
J Mol Biol
, vol.334
, pp. 187-195
-
-
Dhaliwal, S.1
Hoffman, D.W.2
-
10
-
-
77949535720
-
Features and development of Coot
-
P. Emsley, B. Lohkamp, W.G. Scott, and K. Cowtan Features and development of Coot Acta Crystallogr, D Biol Crystallogr 66 2010 486 501
-
(2010)
Acta Crystallogr, D Biol Crystallogr
, vol.66
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
-
11
-
-
0035853762
-
Internal ribosome entry site-mediated translation of a mammalian mRNA is regulated by amino acid availability
-
J. Fernandez, I. Yaman, R. Mishra, W.C. Merrick, M.D. Snider, W.H. Lamers, and et al. Internal ribosome entry site-mediated translation of a mammalian mRNA is regulated by amino acid availability J Biol Chem 276 2001 12285 12291
-
(2001)
J Biol Chem
, vol.276
, pp. 12285-12291
-
-
Fernandez, J.1
Yaman, I.2
Mishra, R.3
Merrick, W.C.4
Snider, M.D.5
Lamers, W.H.6
-
12
-
-
0037166289
-
Regulation of internal ribosomal entry site-mediated translation by phosphorylation of the translation initiation factor eIF2alpha
-
J.M. Fernandez, I. Yaman, P. Sarnow, M.D. Snider, and M. Hatzoglou Regulation of internal ribosomal entry site-mediated translation by phosphorylation of the translation initiation factor eIF2alpha J Biol Chem 277 2002 19198 19205
-
(2002)
J Biol Chem
, vol.277
, pp. 19198-19205
-
-
Fernandez, J.M.1
Yaman, I.2
Sarnow, P.3
Snider, M.D.4
Hatzoglou, M.5
-
13
-
-
34347225099
-
The dsRNA protein kinase PKR: Virus and cell control
-
M.A. Garcia, E.F. Meurs, and M. Esteban The dsRNA protein kinase PKR: virus and cell control Biochimie 89 2007 799 811
-
(2007)
Biochimie
, vol.89
, pp. 799-811
-
-
Garcia, M.A.1
Meurs, E.F.2
Esteban, M.3
-
14
-
-
84899714318
-
Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2alpha
-
B.J. Guan, D. Krokowski, M. Majumder, C.L. Schmotzer, S.R. Kimball, W.C. Merrick, and et al. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2alpha J Biol Chem 289 2014 12593 12611
-
(2014)
J Biol Chem
, vol.289
, pp. 12593-12611
-
-
Guan, B.J.1
Krokowski, D.2
Majumder, M.3
Schmotzer, C.L.4
Kimball, S.R.5
Merrick, W.C.6
-
15
-
-
84861413619
-
Genetic evidence of a long-range RNA-RNA interaction between the genomic 5′ untranslated region and the nonstructural protein 1 coding region in murine and bovine coronaviruses
-
B.J. Guan, Y.P. Su, H.Y. Wu, and D.A. Brian Genetic evidence of a long-range RNA-RNA interaction between the genomic 5′ untranslated region and the nonstructural protein 1 coding region in murine and bovine coronaviruses J Virol 86 2012 4631 4643
-
(2012)
J Virol
, vol.86
, pp. 4631-4643
-
-
Guan, B.J.1
Su, Y.P.2
Wu, H.Y.3
Brian, D.A.4
-
16
-
-
17944362905
-
Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency
-
A.P. Han, C. Yu, L. Lu, Y. Fujiwara, C. Browne, G. Chin, and et al. Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency EMBO J 20 2001 6909 6918
-
(2001)
EMBO J
, vol.20
, pp. 6909-6918
-
-
Han, A.P.1
Yu, C.2
Lu, L.3
Fujiwara, Y.4
Browne, C.5
Chin, G.6
-
17
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
H.P. Harding, Y. Zhang, and D. Ron Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase Nature 397 1999 271 274
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
18
-
-
3943080710
-
The molecular mechanics of eukaryotic translation
-
L.D. Kapp, and J.R. Lorsch The molecular mechanics of eukaryotic translation Annu Rev Biochem 73 2004 657 704
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 657-704
-
-
Kapp, L.D.1
Lorsch, J.R.2
-
19
-
-
1542316306
-
Regulation of mRNA translation by protein folding in the endoplasmic reticulum
-
R.J. Kaufman Regulation of mRNA translation by protein folding in the endoplasmic reticulum Trends Biochem Sci 29 2004 152 158
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 152-158
-
-
Kaufman, R.J.1
-
20
-
-
0026244229
-
MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
-
P. Kraulis MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures J Appl Crystallogr 24 1991 946 950
-
(1991)
J Appl Crystallogr
, vol.24
, pp. 946-950
-
-
Kraulis, P.1
-
21
-
-
84879037139
-
A self-defeating anabolic program leads to beta-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux
-
D. Krokowski, J. Han, M. Saikia, M. Majumder, C.L. Yuan, B.J. Guan, and et al. A self-defeating anabolic program leads to beta-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux J Biol Chem 288 2013 17202 17213
-
(2013)
J Biol Chem
, vol.288
, pp. 17202-17213
-
-
Krokowski, D.1
Han, J.2
Saikia, M.3
Majumder, M.4
Yuan, C.L.5
Guan, B.J.6
-
22
-
-
84863115336
-
A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation
-
M. Majumder, C. Huang, M.D. Snider, A.A. Komar, J. Tanaka, R.J. Kaufman, and et al. A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation Mol Cell Biol 32 2012 992 1003
-
(2012)
Mol Cell Biol
, vol.32
, pp. 992-1003
-
-
Majumder, M.1
Huang, C.2
Snider, M.D.3
Komar, A.A.4
Tanaka, J.5
Kaufman, R.J.6
-
23
-
-
80053285628
-
Akt determines cell fate through inhibition of the PERK-eIF2alpha phosphorylation pathway
-
Z. Mounir, J.L. Krishnamoorthy, S. Wang, B. Papadopoulou, S. Campbell, W.J. Muller, and et al. Akt determines cell fate through inhibition of the PERK-eIF2alpha phosphorylation pathway Sci Signal 4 2011 ra62
-
(2011)
Sci Signal
, vol.4
, pp. ra62
-
-
Mounir, Z.1
Krishnamoorthy, J.L.2
Wang, S.3
Papadopoulou, B.4
Campbell, S.5
Muller, W.J.6
-
24
-
-
0037053309
-
Crystal structure of the N-terminal segment of human eukaryotic translation initiation factor 2alpha
-
M.C. Nonato, J. Widom, and J. Clardy Crystal structure of the N-terminal segment of human eukaryotic translation initiation factor 2alpha J Biol Chem 277 2002 17057 17061
-
(2002)
J Biol Chem
, vol.277
, pp. 17057-17061
-
-
Nonato, M.C.1
Widom, J.2
Clardy, J.3
-
25
-
-
23844554840
-
Structural basis for autoinhibition and mutational activation of eukaryotic initiation factor 2alpha protein kinase GCN2
-
A.K. Padyana, H. Qiu, A. Roll-Mecak, A.G. Hinnebusch, and S.K. Burley Structural basis for autoinhibition and mutational activation of eukaryotic initiation factor 2alpha protein kinase GCN2 J Biol Chem 280 2005 29289 29299
-
(2005)
J Biol Chem
, vol.280
, pp. 29289-29299
-
-
Padyana, A.K.1
Qiu, H.2
Roll-Mecak, A.3
Hinnebusch, A.G.4
Burley, S.K.5
-
26
-
-
84871107922
-
Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress
-
M. Saikia, D. Krokowski, B.J. Guan, P. Ivanov, M. Parisien, G.F. Hu, and et al. Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress J Biol Chem 287 2012 42708 42725
-
(2012)
J Biol Chem
, vol.287
, pp. 42708-42725
-
-
Saikia, M.1
Krokowski, D.2
Guan, B.J.3
Ivanov, P.4
Parisien, M.5
Hu, G.F.6
-
27
-
-
0030783310
-
Homologous regions of the alpha subunit of eukaryotic translational initiation factor 2 (eIF2alpha) and the vaccinia virus K3L gene product interact with the same domain within the dsRNA-activated protein kinase (PKR)
-
T.V. Sharp, J.E. Witzel, and R. Jagus Homologous regions of the alpha subunit of eukaryotic translational initiation factor 2 (eIF2alpha) and the vaccinia virus K3L gene product interact with the same domain within the dsRNA-activated protein kinase (PKR) Eur J Biochem 250 1997 85 91
-
(1997)
Eur J Biochem
, vol.250
, pp. 85-91
-
-
Sharp, T.V.1
Witzel, J.E.2
Jagus, R.3
-
28
-
-
0027186435
-
Mutations in the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2 alpha) that overcome the inhibitory effect of eIF-2 alpha phosphorylation on translation initiation
-
C.R. Vazquez de Aldana, T.E. Dever, and A.G. Hinnebusch Mutations in the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2 alpha) that overcome the inhibitory effect of eIF-2 alpha phosphorylation on translation initiation Proc Natl Acad Sci USA 90 1993 7215 7219
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7215-7219
-
-
Vazquez De Aldana, C.R.1
Dever, T.E.2
Hinnebusch, A.G.3
-
29
-
-
69949167078
-
Genome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2p
-
J.M. Zaborske, J. Narasimhan, L. Jiang, S.A. Wek, K.A. Dittmar, F. Freimoser, and et al. Genome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2p J Biol Chem 284 2009 25254 25267
-
(2009)
J Biol Chem
, vol.284
, pp. 25254-25267
-
-
Zaborske, J.M.1
Narasimhan, J.2
Jiang, L.3
Wek, S.A.4
Dittmar, K.A.5
Freimoser, F.6
-
30
-
-
0036771638
-
The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice
-
P. Zhang, B.C. McGrath, J. Reinert, D.S. Olsen, L. Lei, S. Gill, and et al. The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice Mol Cell Biol 22 2002 6681 6688
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6681-6688
-
-
Zhang, P.1
McGrath, B.C.2
Reinert, J.3
Olsen, D.S.4
Lei, L.5
Gill, S.6
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