Regulation of mouse GADD34 gene transcription after DNA damaging agent methylmethane sulfonate

Gene

Volumn 336, Issue 1, 2004, Pages 139-146

  Haneda, Masataka ^a,b   Xiao, Hengyi ^a   Hasegawa, Tadao ^a   Kimura, Yuko ^a   Nakashima, Izumi ^b   Isobe, Ken Ichi ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

c Jun; DNA damage; GADD; GADD34; growth arrest and DNA damage; methylmethane sulfonate; MMS; Stress response; Transcription

Indexed keywords

DNA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; LUCIFERASE; METHYLMETHANE SULFONATE; STRESS ACTIVATED PROTEIN KINASE; SULFONIC ACID DERIVATIVE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; EMBRYO; ENZYME PHOSPHORYLATION; FIBROBLAST; GENE MUTATION; GENETIC REGULATION; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; TRANSCRIPTION REGULATION;

ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; ANTIGENS, DIFFERENTIATION; BINDING SITES; CELL CYCLE PROTEINS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; LUCIFERASES; MAP KINASE KINASE 4; METHYL METHANESULFONATE; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUTAGENS; MUTATION; NIH 3T3 CELLS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEINS; PROTO-ONCOGENE PROTEINS C-JUN; RECOMBINANT FUSION PROTEINS; RESPONSE ELEMENTS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 3242773749     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2004.04.008     Document Type: Article

References (17)

1. Abdollahi A, Lord K.A, Hoffman-Liebermann B, Liebermann D.A. Interferon regulatory factor 1 is a myeloid differentiation primary response gene induced by interleukin 6 and leukemia inhibitory factor: role in growth inhibition. Cell Growth Differ. 2:1991;401-407
2. Chou J, Roizman B. Herpes simplex virus 1 gamma(1)34.5 gene function, which blocks the host response to infection, maps in the homologous domain of the genes expressed during growth arrest and DNA damage. Proc. Natl. Acad. Sci. U. S. A. 91:1994;5247-5251
3. Derijard B, Hibi M, Wu I.H, Barrett T, Su B, Deng T, Karin M, Davis R.J. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell. 76:1994;1025-1037
4. Fawcett T.W, Martindale J.L, Guyton K.Z, Hai T, Holbrook N.J. Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response. Biochem. J. 339:1999;135-141
5. Fornace A.J Jr., Nebert D.W, Hollander M.C, Luethy J.D, Papathanasiou M, Fargnoli J, Holbrook N.J. Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents. Mol. Cell. Biol. 9:1989;4196-4203
6. Hasegawa T, Xiao H, Isobe K. Cloning of a GADD34-like gene that interacts with the zinc-finger transcription factor which binds to the p21(WAF) promoter. Biochem. Biophys. Res. Commun. 256:1999;249-254
7. He B, Chou J, Liebermann D.A, Hoffman B, Roizman B. The carboxyl terminus of the murine MyD116 gene substitutes for the corresponding domain of the gamma(1)34.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells. J. Virol. 70:1996;84-90
8. Hollander M.C, Zhan Q, Bae I, Fornace A.J Jr. Mammalian, 1997. GADD34, an apoptosis- and DNA damage-inducible gene. J. Biol. Chem. 272:1997;13731-13737
9. Jiang H.Y, Wek S.A, McGrath B.C, Lu D, Hai T, Harding H.P, Wang X, Ron D, Cavener D.R, Wek R.C. Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response. Mol. Cell. Biol. 24:2004;1365-1377
10. Kojima E, Takeuchi A, Haneda M, Yagi A, Hasegawa T, Yamaki K, Takeda K, Akira S, Shimokata K, Isobe K. The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice. FASEB J. 17:2003;1573-1575
11. Kyriakis J.M, Banerjee P, Nikolakaki E, Dai T, Rubie E.A, Ahmad M.F, Avruch J, Woodgett J.R. The stress-activated protein kinase subfamily of c-Jun kinases. Nature. 369:1994;156-160
12. Novoa I, Zeng H, Harding H.P, Ron D. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J. Cell Biol. 153:2001;1011-1022
13. Novoa I, Zhang Y, Zeng H, Jungreis R, Harding H.P, Ron D. Stress-induced gene expression requires programmed recovery from translational repression. EMBO J. 22:2003;1180-1187
14. Wilhelm D, Bender K, Knebel A, Angel P. The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents. Mol. Cell. Biol. 17:1997;4792-4800
15. Xiao H, Hasegawa T, Isobe K. Both Sp1 and Sp3 are responsible for p21waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells. J. Cell. Biochem. 73:1999;291-302
16. Yagi A, Hasegawa Y, Xiao H, Haneda M, Kojima E, Nishikimi A, Hasegawa T, Shimokata K, Isobe K. GADD34 induces p53 phosphorylation and p21/WAF1 transcription. J. Cell. Biochem. 90:2003;1242-1249
17. Zhan Q, Lord K.A, Alamo I Jr., Hollander M.C, Carrier F, Ron D, Kohn K.W, Hoffman B, Liebermann D.A, Fornace A.J Jr. The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Mol. Cell. Biol. 14:1994;2361-2371