Indexed keywords
2 (2 CHLOROPHENYL) 5 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 1,3,4 OXADIAZOLE;
2 (3 CHLOROPHENYL) 5 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 1,3,4 OXADIAZOLE;
2 (3,4 DIMETHOXYPHENYL) 5 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 1,3,4 OXADIAZOLE;
2 (4 CHLOROPHENYL) 5 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 5 (2 FLUOROPHENYL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 5 (3 FLUOROPHENYL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 5 (4 FLUOROPHENYL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 5 (4 METHOXYPHENYL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 5 (4 NITROPHENYL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 5 (M TOLYL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 5 (O TOLYL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 5 (PYRIDIN 2 YL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 5 (PYRIDIN 4 YL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL]5 (3 NITROPHENYL) 1,3,4 OXADIAZOLE;
2 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL]5 (PYRIDIN 3 YL) 1,3,4 OXADIAZOLE;
2 [5 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 1,3,4 OXADIAZOL 2 YL]PHENOL;
3 [5 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 1,3,4 OXADIAZOL 2 YL]PHENOL;
4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)BENZOHYDRAZIDE;
4 [5 [4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)PHENYL] 1,3,4 OXADIAZOL 2YL]PHENOL;
BETA GLUCURONIDASE;
GLYCOSIDASE INHIBITOR;
METHYL 4 (5,6 DIMETHYL 1H BENZO[D]IMIDAZOL 2 YL)BENZOATE;
SACCHARIC ACID;
UNCLASSIFIED DRUG;
BENZIMIDAZOLE DERIVATIVE;
ENZYME INHIBITOR;
OXADIAZOLE DERIVATIVE;
PROTEIN BINDING;
ARTICLE;
COMPUTER MODEL;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG BINDING;
DRUG POTENCY;
DRUG SELECTIVITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME ACTIVE SITE;
ENZYME INHIBITION;
IC50;
MOLECULAR DOCKING;
ANTAGONISTS AND INHIBITORS;
CHEMISTRY;
HUMAN;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
BENZIMIDAZOLES;
CATALYTIC DOMAIN;
ENZYME INHIBITORS;
GLUCURONIDASE;
HUMANS;
MOLECULAR DOCKING SIMULATION;
OXADIAZOLES;
PROTEIN BINDING;
STRUCTURE-ACTIVITY RELATIONSHIP;
2
0002712988
β-glucuronidases in metabolic hydrolysis
Fishman W.H. (Ed.) Academic Press Inc: New York
Wakabayashi, M. β-glucuronidases in metabolic hydrolysis. in: Fishman W.H. (Ed.) Metabolic conjugation and metabolic hydrolysis. Vol. 2. Academic Press Inc: New York; 1970, 519.
(1970)
Metabolic conjugation and metabolic hydrolysis
, vol.2
, pp. 519
Wakabayashi, M.1
9
0015075950
A.R. Ronald, F. Silverblatt, H. Clark, R.E. Cutler, and M. Turck Appl. Microbiol. 21 1971 990
(1971)
Appl. Microbiol.
, vol.21
, pp. 990
Ronald, A.R.1
Silverblatt, F.2
Clark, H.3
Cutler, R.E.4
Turck, M.5
16
84879718744
K.M. Khan, M. Khan, M. Saleem, M. Taha, S. Perveen, and M.I. Choudhary J. Pak. Chem Soc. 35 2013 901
(2013)
J. Pak. Chem Soc.
, vol.35
, pp. 901
Khan, K.M.1
Khan, M.2
Saleem, M.3
Taha, M.4
Perveen, S.5
Choudhary, M.I.6
17
85027926278
Z.S. Saify, A. Kamil, S. Akhtar, M. Taha, A. Khan, K.M. Khan, S. Jahan, F. Rahim, S. Perveen, and M.I. Choudhary Med. Chem. Res. 23 2014 4447
(2014)
Med. Chem. Res.
, vol.23
, pp. 4447
Saify, Z.S.1
Kamil, A.2
Akhtar, S.3
Taha, M.4
Khan, A.5
Khan, K.M.6
Jahan, S.7
Rahim, F.8
Perveen, S.9
Choudhary, M.I.10
20
0022485065
R. Iemura, T. Kawashima, T. Fukuda, K. Ito, and G. Tsukamoto J. Med. Chem. 29 1986 1178
(1986)
J. Med. Chem.
, vol.29
, pp. 1178
Iemura, R.1
Kawashima, T.2
Fukuda, T.3
Ito, K.4
Tsukamoto, G.5
21
0032554878
T.C. Kuhler, M. Swanson, V. Shcherbuchin, H. Larsson, B. Mellgard, and J.E. Sjostrom J. Med. Chem. 41 1998 1777
(1998)
J. Med. Chem.
, vol.41
, pp. 1777
Kuhler, T.C.1
Swanson, M.2
Shcherbuchin, V.3
Larsson, H.4
Mellgard, B.5
Sjostrom, J.E.6
24
0034194347
Z. Zhao, D.O. Arnaiz, B. Griedel, S. Sakata, J.L. Dallas, M. Whitlow, L. Trinh, J. Post, A. Liang, M.M. Morrissey, and K.J. Shaw Bioorg. Med. Chem. Lett. 10 2000 963
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 963
Zhao, Z.1
Arnaiz, D.O.2
Griedel, B.3
Sakata, S.4
Dallas, J.L.5
Whitlow, M.6
Trinh, L.7
Post, J.8
Liang, A.9
Morrissey, M.M.10
Shaw, K.J.11
25
41849101471
A. Kamal, P.P. Kumar, K. Sreekanth, B.N. Seshadri, and P. Ramulu Bioorg. Med. Chem. Lett. 18 2008 2594
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 2594
Kamal, A.1
Kumar, P.P.2
Sreekanth, K.3
Seshadri, B.N.4
Ramulu, P.5
26
33144486131
T. Ishida, T. Suzuki, S. Hirashima, K. Mizutani, A. Yoshida, I. Ando, S. Ikeda, T. Adachi, and H. Hashimoto Bioorg. Med. Chem. Lett. 16 2006 1859
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 1859
Ishida, T.1
Suzuki, T.2
Hirashima, S.3
Mizutani, K.4
Yoshida, A.5
Ando, I.6
Ikeda, S.7
Adachi, T.8
Hashimoto, H.9
27
84937485958
United States patent
Hohard, A.H.; John, A.R. United States patent. Patent number 3146240, 1964.
(1964)
Hohard, A.H.1
John, A.R.2
30
0036501101
S.G. Kucukguzel, E.E. Oruc, S. Rollas, F. Sahin, and A. Ozbek Eur. J. Med. Chem. 37 2002 197
(2002)
Eur. J. Med. Chem.
, vol.37
, pp. 197
Kucukguzel, S.G.1
Oruc, E.E.2
Rollas, S.3
Sahin, F.4
Ozbek, A.5
31
0037234373
D. Chauhan, J.S. Chauhan, J. Singh, S.K. Bajpai, and M.N. Joshi Indian J. Chem. 42B 2003 215
(2003)
Indian J. Chem.
, vol.42 B
, pp. 215
Chauhan, D.1
Chauhan, J.S.2
Singh, J.3
Bajpai, S.K.4
Joshi, M.N.5
35
0027949227
M. Santagati, M. Modica, A. Santagati, F. Russo, A. Caruso, and V. Cutuli Pharmazie 49 1994 880
(1994)
Pharmazie
, vol.49
, pp. 880
Santagati, M.1
Modica, M.2
Santagati, A.3
Russo, F.4
Caruso, A.5
Cutuli, V.6
36
0027221539
M.D. Mullican, M.W. Wilson, D.T. Connor, C.R. Kostlan, D.J. Schrier, and R.D. Dyer J. Med. Chem. 36 1993 1090
(1993)
J. Med. Chem.
, vol.36
, pp. 1090
Mullican, M.D.1
Wilson, M.W.2
Connor, D.T.3
Kostlan, C.R.4
Schrier, D.J.5
Dyer, R.D.6
39
3743125601
French Pat
Maillard, J.; Vincent, M.; Morin, R.; Bernard, M. French Pat M379; Chem Abstr. 1962, 57,15251g.
(1962)
Chem Abstr.
, vol.52
, pp. 15251g
Maillard, J.1
Vincent, M.2
Morin, R.3
Bernard, M.4
40
20044362923
K.A. Jessen, N.M. English, J.Y. Wang, S.K. Maliartenou, S.P. Archer, and L. Qiu Mol. Cancer Ther. 4 2005 761
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 761
Jessen, K.A.1
English, N.M.2
Wang, J.Y.3
Maliartenou, S.K.4
Archer, S.P.5
Qiu, L.6
42
0037227705
S. Cao, X.H. Qian, G. Song, B. Chai, and Z. Jiang J. Agric. Food Chem. 15 2003 152
(2003)
J. Agric. Food Chem.
, vol.15
, pp. 152
Cao, S.1
Qian, X.H.2
Song, G.3
Chai, B.4
Jiang, Z.5
43
84937485959
K.M. Khan, F. Rahim, A. Wadood, M. Taha, M. Khan, S. Naureen, N. Ambreen, S. Hussain, S. Perveen, and M.I. Choudhary Bioorg. Med. Chem. Lett. 2014 1825 24
(1825)
Bioorg. Med. Chem. Lett.
, vol.2014
, pp. 24
Khan, K.M.1
Rahim, F.2
Wadood, A.3
Taha, M.4
Khan, M.5
Naureen, S.6
Ambreen, N.7
Hussain, S.8
Perveen, S.9
Choudhary, M.I.10
44
84893344425
K.M. Khan, F. Naz, M. Taha, A. Khan, S. Perveen, M.I. Choudhary, and W. Voelter Eur. J. Med. Chem. 74 2014 314
(2014)
Eur. J. Med. Chem.
, vol.74
, pp. 314
Khan, K.M.1
Naz, F.2
Taha, M.3
Khan, A.4
Perveen, S.5
Choudhary, M.I.6
Voelter, W.7
45
84901047505
K.M. Khan, F. Rahim, A. Wadood, N. Kosar, M. Taha, S. Lalani, A. Khan, M.I. Fakhri, M. Junaid, W. Rehman, M. Khan, S. Perveen, M. Sajid, and M.I. Choudhary Eur. J. Med. Chem. 81 2014 245
(2014)
Eur. J. Med. Chem.
, vol.81
, pp. 245
Khan, K.M.1
Rahim, F.2
Wadood, A.3
Kosar, N.4
Taha, M.5
Lalani, S.6
Khan, A.7
Fakhri, M.I.8
Junaid, M.9
Rehman, W.10
Khan, M.11
Perveen, S.12
Sajid, M.13
Choudhary, M.I.14
46
84919941245
F. Rahim, K. Ullah, H. Ullah, A. Wadood, M. Taha, A.U. Rehman, M. Ashraf, A. Shaukat, W. Rehman, S. Hussain, and K.M. Khan Bioorg. Chem. 58 2015 81
(2015)
Bioorg. Chem.
, vol.58
, pp. 81
Rahim, F.1
Ullah, K.2
Ullah, H.3
Wadood, A.4
Taha, M.5
Rehman, A.U.6
Ashraf, M.7
Shaukat, A.8
Rehman, W.9
Hussain, S.10
Khan, K.M.11
47
84920848432
M. Taha, N.H. Ismail, S. Lalani, M.Q. Fatmi, Atia-tul-Wahab, S. Siddiqui, K.M. Khan, S. Imran, and M.I. Choudhary Eur. J. Med. Chem. 92 2015 387
(2015)
Eur. J. Med. Chem.
, vol.92
, pp. 387
Taha, M.1
Ismail, N.H.2
Lalani, S.3
Fatmi, M.Q.4
Atia-Tul-Wahab5
Siddiqui, S.6
Khan, K.M.7
Imran, S.8
Choudhary, M.I.9
48
84863395182
K.M. Khan, Z. Shah, V.U. Ahmad, N. Ambreen, M. Khan, M. Taha, F. Rahim, S. Noreen, S. Perveen, M.I. Choudhary, and W. Voelter Bioorg. Med. Chem. 20 2012 1521
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 1521
Khan, K.M.1
Shah, Z.2
Ahmad, V.U.3
Ambreen, N.4
Khan, M.5
Taha, M.6
Rahim, F.7
Noreen, S.8
Perveen, S.9
Choudhary, M.I.10
Voelter, W.11
49
84905161829
M. Taha, N.H. Ismail, W. Jamil, H. Rashwan, S.M. Kashif, A.A. Sain, M.I. Adenan, E.H. Anouar, M. Ali, F. Rahim, and K.M. Khan Eur. J. Med. Chem. 84 2014 731
(2014)
Eur. J. Med. Chem.
, vol.84
, pp. 731
Taha, M.1
Ismail, N.H.2
Jamil, W.3
Rashwan, H.4
Kashif, S.M.5
Sain, A.A.6
Adenan, M.I.7
Anouar, E.H.8
Ali, M.9
Rahim, F.10
Khan, K.M.11
51
0031394840
R.A. Collins, T.B. Ng, W.P. Fong, C.C. Wan, and H.W. Yeung Biochem. Mol. Biol. Int. 42 1997 1163
(1997)
Biochem. Mol. Biol. Int.
, vol.42
, pp. 1163
Collins, R.A.1
Ng, T.B.2
Fong, W.P.3
Wan, C.C.4
Yeung, H.W.5
52
84898829844
K.M. Khan, A. Karim, S. Saied, N. Ambreen, X. Rustamova, S. Naureen, S. Mansoor, M. Ali, S. Perveen, M.I. Choudhary, and G.A. Morales Mol. Divers. 18 2014 295
(2014)
Mol. Divers.
, vol.18
, pp. 295
Khan, K.M.1
Karim, A.2
Saied, S.3
Ambreen, N.4
Rustamova, X.5
Naureen, S.6
Mansoor, S.7
Ali, M.8
Perveen, S.9
Choudhary, M.I.10
Morales, G.A.11
53
84904816945
W. Jamil, S. Perveen, S.A.A. Shah, M. Taha, N.H. Ismail, S. Perveen, N. Ambreen, K.M. Khan, and M.I. Choudhary Molecules 19 2014 8788
(2014)
Molecules
, vol.19
, pp. 8788
Jamil, W.1
Perveen, S.2
Shah, S.A.A.3
Taha, M.4
Ismail, N.H.5
Perveen, S.6
Ambreen, N.7
Khan, K.M.8
Choudhary, M.I.9
54
84901927895
K.M. Khan, S.M. Saad, N.N. Shaikh, S. Hussain, M.I. Fakhri, S. Perveen, M. Taha, and M.I. Choudhary Bioorg. Med. Chem. 22 2014 3449
(2014)
Bioorg. Med. Chem.
, vol.22
, pp. 3449
Khan, K.M.1
Saad, S.M.2
Shaikh, N.N.3
Hussain, S.4
Fakhri, M.I.5
Perveen, S.6
Taha, M.7
Choudhary, M.I.8
55
84904440676
K.M. Khan, N. Ambreen, M. Taha, S.A. Halim, Zaheer-ul-Haq, S. Naureen, S. Rasheed, S. Perveen, S. Ali, and M.I. Choudhary J. Comput. Aided Mol. Des. 28 2014 577
(2014)
J. Comput. Aided Mol. Des.
, vol.28
, pp. 577
Khan, K.M.1
Ambreen, N.2
Taha, M.3
Halim, S.A.4
Zaheer-Ul-Haq5
Naureen, S.6
Rasheed, S.7
Perveen, S.8
Ali, S.9
Choudhary, M.I.10