Synthesis of novel derivatives of 4-methylbenzimidazole and evaluation of their biological activities

European Journal of Medicinal Chemistry

Volumn 84, Issue , 2014, Pages 731-738

  Taha, Muhammad ^a,b   Ismail, Nor Hadiani ^a,b   Jamil, Waqas ^c   Rashwan, Hesham ^a   Kashif, Syed Muhammad ^c   Sain, Amyra Amat ^d   Adenan, Mohd Ilham ^a,d,e   Anouar, El Hassane ^a   Ali, Muhammad ^f   Rahim, Fazal ^h   Khan, Khalid M ^g  

^a UNIVERSITI TEKNOLOGI MARA   (Malaysia)

^b Faculty of Civil Engineering (UiTM)   (Malaysia)

^c UNIVERSITY OF SINDH   (Pakistan)

^d Kemeneterian Sains Teknologi dan Inovasi   (Malaysia)

^e FOREST RESEARCH INSTITUTE MALAYSIA   (Malaysia)

^f Forest Research Institute Malaysia ^*  (Pakistan)

^g UNIVERSITY OF KARACHI   (Pakistan)

^h HAZARA UNIVERSITY   (Pakistan)

Author keywords

Antiglycation; Antileishmanial; Antioxidant; Benzimidazole; Stereoisomers

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 4 METHYLBENZIMIDAZOLE DERIVATIVE; ANTIDIABETIC AGENT; ANTILEISHMANIAL AGENT; ANTIOXIDANT; BENZIMIDAZOLE DERIVATIVE; CYTOTOXIC AGENT; GALLIC ACID PROPYL ESTER; RUTOSIDE; SUPEROXIDE; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; DISULFIDE; HYDRAZIDE DERIVATIVE; HYDRAZONE DERIVATIVE; HYDROXYL GROUP; MORPHINE;

ANTIGLYCATION ACTIVITY; ANTILEISHMANIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CYTOTOXICITY ACTIVITY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; GLYCATION; HYDROGEN BOND; IC 50; STEREOCHEMISTRY; STEREOSPECIFICITY; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SENSITIVITY; GLYCOSYLATION; HUMAN; LEISHMANIA; SYNTHESIS; CONTROLLED STUDY; CYTOTOXICITY; DPPH RADICAL SCAVENGING ASSAY; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; IC50; LEISHMANIASIS; STRUCTURE ACTIVITY RELATION; THP 1 CELL LINE;

ANTIOXIDANTS; ANTIPROTOZOAL AGENTS; BENZIMIDAZOLES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOSYLATION; HUMANS; LEISHMANIA; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS;

EID: 84905161829     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.07.078     Document Type: Article

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