Self-assembling bubble carriers for oral protein delivery

Biomaterials

Volumn 64, Issue , 2015, Pages 115-124

  Chuang, Er Yuan ^a   Lin, Kun Ju ^b,c   Lin, Po Yen ^a   Chen, Hsin Lung ^a   Wey, Shiaw Pyng ^b   Mi, Fwu Long ^d   Hsiao, Hsu Chan ^a   Chen, Chiung Tong ^e   Sung, Hsing Wen ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Biodistribution; Colloidal carrier; Foaming agent; Oral protein delivery; Surfactant

Indexed keywords

BLOWING AGENTS; BUBBLES (IN FLUIDS); CARBON DIOXIDE; COLLOIDS; CONTROLLED DRUG DELIVERY; DRUG PRODUCTS; INSULIN; MOLECULES; PROTEINS; SODIUM BICARBONATE; SULFUR COMPOUNDS; SURFACE ACTIVE AGENTS; TARGETED DRUG DELIVERY;

ABSORPTION-ENHANCERS; BIODISTRIBUTIONS; COLLOIDAL CARRIERS; EPITHELIAL PERMEABILITY; ORAL PROTEIN DELIVERY; SELF ASSEMBLED FILMS; SURFACTANT MOLECULES; SYSTEMIC CIRCULATION;

SODIUM DODECYL SULFATE;

BICARBONATE; CARBON DIOXIDE; DODECYL SULFATE SODIUM; DRUG CARRIER; FOAMING AGENT; GELATIN; INSULIN; NANOBUBBLE; PENTETIC ACID; SURFACTANT; ENTERIC COATED TABLET; MICROCAPSULE; PROTEIN;

ACIDITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; COLLOID; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CAPSULE; DRUG DECOMPOSITION; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG TRANSPORT; FEMALE; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; INTESTINE FLUID; LEAF AREA; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; SYSTEMIC CIRCULATION; ANIMAL; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; ENTERIC COATED TABLET; INTESTINE ABSORPTION; MICROBUBBLE; MICROCAPSULE; ORAL DRUG ADMINISTRATION; PERMEABILITY; PROTEIN DEGRADATION; RANDOMIZATION; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOLUBILITY; TISSUE DISTRIBUTION; TOXICITY; TUMOR CELL LINE; WISTAR RAT;

RATTUS;

ADMINISTRATION, ORAL; ANIMALS; CAPSULES; CELL LINE, TUMOR; DIABETES MELLITUS, EXPERIMENTAL; DRUG CARRIERS; GELATIN; INSULIN; INTESTINAL ABSORPTION; MICROBUBBLES; PENTETIC ACID; PERMEABILITY; PROTEINS; PROTEOLYSIS; RANDOM ALLOCATION; RATS; RATS, WISTAR; SODIUM DODECYL SULFATE; SOLUBILITY; TABLETS, ENTERIC-COATED; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 84937434579     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.06.035     Document Type: Article

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