메뉴 건너뛰기




Volumn 16, Issue 1, 2015, Pages

Epigenome data release: A participant-centered approach to privacy protection

Author keywords

[No Author keywords available]

Indexed keywords

ACCESS TO INFORMATION; ARTICLE; BASE PAIRING; CASE STUDY; DNA EXTRACTION; DNA METHYLATION; EPIGENETICS; GENE MAPPING; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; HUMAN GENOME; INFORMATION DISSEMINATION; INFORMATION PROCESSING; PRACTICE GUIDELINE; PRIVACY; ANONYMIZATION; DNA SEQUENCE; GENETIC EPIGENESIS; GENETIC PRIVACY; GENETIC VARIATION; HIGH THROUGHPUT SEQUENCING; HUMAN;

EID: 84937215130     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0723-0     Document Type: Article
Times cited : (34)

References (63)
  • 1
    • 84890172667 scopus 로고    scopus 로고
    • Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
    • Grundberg E, Meduri E, Sandling JK, Hedman AK, Keildson S, Buil A, et al. Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. Am J Hum Genet. 2013;93:876-90.
    • (2013) Am J Hum Genet , vol.93 , pp. 876-890
    • Grundberg, E.1    Meduri, E.2    Sandling, J.K.3    Hedman, A.K.4    Keildson, S.5    Buil, A.6
  • 2
    • 84901005679 scopus 로고    scopus 로고
    • Routes for breaching and protecting genetic privacy
    • Erlich Y, Narayanan A. Routes for breaching and protecting genetic privacy. Nat Rev Genet. 2014;15:409-21.
    • (2014) Nat Rev Genet , vol.15 , pp. 409-421
    • Erlich, Y.1    Narayanan, A.2
  • 3
    • 3042849144 scopus 로고    scopus 로고
    • Genetics. Genomic research and human subject privacy
    • Lin Z, Owen AB, Altman RB. Genetics. Genomic research and human subject privacy. Science. 2004;305:183.
    • (2004) Science , vol.305 , pp. 183
    • Lin, Z.1    Owen, A.B.2    Altman, R.B.3
  • 4
    • 11444251712 scopus 로고    scopus 로고
    • Selection of twenty-four highly informative SNP markers for human identification and paternity analysis in Koreans
    • Lee HY, Park MJ, Yoo JE, Chung U, Han GR, Shin KJ. Selection of twenty-four highly informative SNP markers for human identification and paternity analysis in Koreans. Forensic Sci Int. 2005;148:107-12.
    • (2005) Forensic Sci Int , vol.148 , pp. 107-112
    • Lee, H.Y.1    Park, M.J.2    Yoo, J.E.3    Chung, U.4    Han, G.R.5    Shin, K.J.6
  • 5
    • 80053317645 scopus 로고    scopus 로고
    • Genomic databases access agreements: legal validity and possible sanctions
    • Joly Y, Zeps N, Knoppers BM. Genomic databases access agreements: legal validity and possible sanctions. Hum Genet. 2011;130:441-9.
    • (2011) Hum Genet , vol.130 , pp. 441-449
    • Joly, Y.1    Zeps, N.2    Knoppers, B.M.3
  • 6
    • 84855281324 scopus 로고    scopus 로고
    • Genomics and privacy: implications of the new reality of closed data for the field
    • Greenbaum D, Sboner A, Mu XJ, Gerstein M. Genomics and privacy: implications of the new reality of closed data for the field. PLoS Comput Biol. 2011;7:e1002278.
    • (2011) PLoS Comput Biol , vol.7 , pp. e1002278
    • Greenbaum, D.1    Sboner, A.2    Mu, X.J.3    Gerstein, M.4
  • 7
    • 84937206753 scopus 로고    scopus 로고
    • (NOT-OD-14-124)
    • National Institutes of Health. NIH Genomic Data Sharing Policy (NOT-OD-14-124). 2014. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-14-124.html Accessed 1 July 2015.
    • (2014) NIH Genomic Data Sharing Policy
  • 10
    • 78149243538 scopus 로고    scopus 로고
    • DataSHIELD: resolving a conflict in contemporary bioscience - performing a pooled analysis of individual-level data without sharing the data
    • Wolfson M, Wallace SE, Masca N, Rowe G, Sheehan NA, Ferretti V, et al. DataSHIELD: resolving a conflict in contemporary bioscience - performing a pooled analysis of individual-level data without sharing the data. Int J Epidemiol. 2010;39:1372-82.
    • (2010) Int J Epidemiol , vol.39 , pp. 1372-1382
    • Wolfson, M.1    Wallace, S.E.2    Masca, N.3    Rowe, G.4    Sheehan, N.A.5    Ferretti, V.6
  • 11
    • 84887100688 scopus 로고    scopus 로고
    • The Cancer Genome Atlas Data Portal
    • Data Levels and Data Types. The Cancer Genome Atlas Data Portal. https://tcga-data.nci.nih.gov/tcga/tcgaDataType.jsp Accessed 1 July 2015.
    • Data Levels and Data Types
  • 12
    • 84887320563 scopus 로고    scopus 로고
    • Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription
    • Kilpinen H, Waszak SM, Gschwind AR, Raghav SK, Witwicki RM, Orioli A, et al. Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription. Science. 2013;342:744-7.
    • (2013) Science , vol.342 , pp. 744-747
    • Kilpinen, H.1    Waszak, S.M.2    Gschwind, A.R.3    Raghav, S.K.4    Witwicki, R.M.5    Orioli, A.6
  • 14
    • 84887322043 scopus 로고    scopus 로고
    • Identification of genetic variants that affect histone modifications in human cells
    • McVicker G, van de Geijn B, Degner JF, Cain CE, Banovich NE, Raj A, et al. Identification of genetic variants that affect histone modifications in human cells. Science. 2013;342:747-9.
    • (2013) Science , vol.342 , pp. 747-749
    • McVicker, G.1    Geijn, B.2    Degner, J.F.3    Cain, C.E.4    Banovich, N.E.5    Raj, A.6
  • 16
    • 84866853818 scopus 로고    scopus 로고
    • BSmooth: from whole genome bisulfite sequencing reads to differentially methylated regions
    • Hansen KD, Langmead B, Irizarry RA. BSmooth: from whole genome bisulfite sequencing reads to differentially methylated regions. Genome Biol. 2012;13:R83.
    • (2012) Genome Biol , vol.13 , pp. R83
    • Hansen, K.D.1    Langmead, B.2    Irizarry, R.A.3
  • 17
    • 77954362183 scopus 로고    scopus 로고
    • Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine
    • Jin SG, Kadam S, Pfeifer GP. Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine. Nucleic Acids Res. 2010;38:e125.
    • (2010) Nucleic Acids Res , vol.38 , pp. e125
    • Jin, S.G.1    Kadam, S.2    Pfeifer, G.P.3
  • 18
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • Guo JU, Su Y, Zhong C, Ming GL, Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell. 2011;145:423-34.
    • (2011) Cell , vol.145 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 19
    • 84863565553 scopus 로고    scopus 로고
    • Bis-SNP: combined DNA methylation and SNP calling for Bisulfite-seq data
    • Liu Y, Siegmund KD, Laird PW, Berman BP. Bis-SNP: combined DNA methylation and SNP calling for Bisulfite-seq data. Genome Biol. 2012;13:R61.
    • (2012) Genome Biol , vol.13 , pp. R61
    • Liu, Y.1    Siegmund, K.D.2    Laird, P.W.3    Berman, B.P.4
  • 20
    • 84914817989 scopus 로고    scopus 로고
    • MethylExtract: high-quality methylation maps and SNV calling from whole genome bisulfite sequencing data
    • Barturen G, Rueda A, Oliver JL, Hackenberg M. MethylExtract: high-quality methylation maps and SNV calling from whole genome bisulfite sequencing data. F1000Res. 2013;2:217.
    • (2013) F1000Res , vol.2 , pp. 217
    • Barturen, G.1    Rueda, A.2    Oliver, J.L.3    Hackenberg, M.4
  • 22
    • 84937227658 scopus 로고    scopus 로고
    • McGill Epigenomics Mapping Centre Portal. Accessed 1 July 2015.
    • McGill Epigenomics Mapping Centre Portal. http://epigenomesportal.ca Accessed 1 July 2015.
  • 23
    • 84931274676 scopus 로고    scopus 로고
    • Characterization of functional methylomes by next-generation capture sequencing identifies novel disease associated variants
    • Allum F, Shao X, Guénard F, Simon MM, Busche S, Caron M, et al. Characterization of functional methylomes by next-generation capture sequencing identifies novel disease associated variants. Nat Commun. 2015;6:7211.
    • (2015) Nat Commun , vol.6 , pp. 7211
    • Allum, F.1    Shao, X.2    Guénard, F.3    Simon, M.M.4    Busche, S.5    Caron, M.6
  • 24
    • 84880909300 scopus 로고    scopus 로고
    • Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia
    • Busche S, Ge B, Vidal R, Spinella JF, Saillour V, Richer C, et al. Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia. Cancer Res. 2013;73:4323-36.
    • (2013) Cancer Res , vol.73 , pp. 4323-4336
    • Busche, S.1    Ge, B.2    Vidal, R.3    Spinella, J.F.4    Saillour, V.5    Richer, C.6
  • 25
  • 26
    • 0035753329 scopus 로고    scopus 로고
    • Re-identification of DNA through an automated linkage process
    • Malin B, Sweeney L. Re-identification of DNA through an automated linkage process. Proc AMIA Symp. 2001:423-7.
    • (2001) Proc AMIA Symp. , pp. 423-427
    • Malin, B.1    Sweeney, L.2
  • 28
    • 84937227659 scopus 로고    scopus 로고
    • Protecting sensitive health information in the context of health information technology. June 2010. Accessed 1 July 2015.
    • Consumer Partnership for eHealth. Protecting sensitive health information in the context of health information technology. June 2010. http://www.nationalpartnership.org/research-library/health-care/HIT/protecting-sensitive-health.pdf Accessed 1 July 2015.
    • Consumer Partnership for eHealth
  • 29
    • 84902032340 scopus 로고    scopus 로고
    • Pagon RA, Adam MP, Ardinger HH, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington; 1993-2015.
    • Kaback MM, Desnick RJ. Hexosaminidase A Deficiency. In: Pagon RA, Adam MP, Ardinger HH, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington; 1993-2015.
    • Hexosaminidase A Deficiency
    • Kaback, M.M.1    Desnick, R.J.2
  • 31
    • 84896718645 scopus 로고    scopus 로고
    • Aging of blood can be tracked by DNA methylation changes at just three CpG sites
    • Weidner CI, Lin Q, Koch CM, Eisele L, Beier F, Ziegler P, et al. Aging of blood can be tracked by DNA methylation changes at just three CpG sites. Genome Biol. 2014;15:R24.
    • (2014) Genome Biol , vol.15 , pp. R24
    • Weidner, C.I.1    Lin, Q.2    Koch, C.M.3    Eisele, L.4    Beier, F.5    Ziegler, P.6
  • 33
    • 77953149045 scopus 로고    scopus 로고
    • Evaluating re-identification risks with respect to the HIPAA privacy rule
    • Benitez K, Malin B. Evaluating re-identification risks with respect to the HIPAA privacy rule. J Am Med Inform Assoc. 2010;17:169-77.
    • (2010) J Am Med Inform Assoc , vol.17 , pp. 169-177
    • Benitez, K.1    Malin, B.2
  • 34
    • 0037111868 scopus 로고    scopus 로고
    • Genetics. Toward a new vocabulary of human genetic variation
    • Sankar P, Cho MK. Genetics. Toward a new vocabulary of human genetic variation. Science. 2002;298:1337-8.
    • (2002) Science , vol.298 , pp. 1337-1338
    • Sankar, P.1    Cho, M.K.2
  • 37
    • 3142773390 scopus 로고    scopus 로고
    • Integrating ethics and science in the International HapMap Project
    • International HapMap Consortium. Integrating ethics and science in the International HapMap Project. Nat Rev Genet. 2004;5:467-75.
    • (2004) Nat Rev Genet , vol.5 , pp. 467-475
  • 38
    • 43949132118 scopus 로고    scopus 로고
    • The standardization of race and ethnicity in biomedical science editorials and UK biobanks
    • Smart A, Tutton R, Martin P, Ellison GT, Ashcroft R. The standardization of race and ethnicity in biomedical science editorials and UK biobanks. Soc Stud Sci. 2008;38:407-23.
    • (2008) Soc Stud Sci , vol.38 , pp. 407-423
    • Smart, A.1    Tutton, R.2    Martin, P.3    Ellison, G.T.4    Ashcroft, R.5
  • 39
    • 62649102411 scopus 로고    scopus 로고
    • Inferential genotyping of Y chromosomes in Latter-Day Saints founders and comparison to Utah samples in the HapMap project
    • Gitschier J. Inferential genotyping of Y chromosomes in Latter-Day Saints founders and comparison to Utah samples in the HapMap project. Am J Hum Genet. 2009;84:251-8.
    • (2009) Am J Hum Genet , vol.84 , pp. 251-258
    • Gitschier, J.1
  • 40
    • 84860329478 scopus 로고    scopus 로고
    • Bayesian method to predict individual SNP genotypes from gene expression data
    • Schadt EE, Woo S, Hao K. Bayesian method to predict individual SNP genotypes from gene expression data. Nat Genet. 2012;44:603-8.
    • (2012) Nat Genet , vol.44 , pp. 603-608
    • Schadt, E.E.1    Woo, S.2    Hao, K.3
  • 41
    • 84866919003 scopus 로고    scopus 로고
    • Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging
    • Miura F, Enomoto Y, Dairiki R, Ito T. Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging. Nucleic Acids Res. 2012;40:e136.
    • (2012) Nucleic Acids Res , vol.40 , pp. e136
    • Miura, F.1    Enomoto, Y.2    Dairiki, R.3    Ito, T.4
  • 42
    • 70450169678 scopus 로고    scopus 로고
    • Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns
    • Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, et al. Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet. 2009;18:4808-17.
    • (2009) Hum Mol Genet , vol.18 , pp. 4808-4817
    • Byun, H.M.1    Siegmund, K.D.2    Pan, F.3    Weisenberger, D.J.4    Kanel, G.5    Laird, P.W.6    Yang, A.S.7
  • 43
    • 84874353239 scopus 로고    scopus 로고
    • Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray
    • Chen YA, Lemire M, Choufani S, Butcher DT, Grafodatskaya D, Zanke BW, et al. Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray. Epigenetics. 2013;8:203-9.
    • (2013) Epigenetics , vol.8 , pp. 203-209
    • Chen, Y.A.1    Lemire, M.2    Choufani, S.3    Butcher, D.T.4    Grafodatskaya, D.5    Zanke, B.W.6
  • 44
    • 84937227660 scopus 로고    scopus 로고
    • US-EU Safe Harbor Framework Documents. Accessed 3 July 2015.
    • US-EU Safe Harbor Framework Documents. http://www.export.gov/safeharbor/eu/ Accessed 3 July 2015.
  • 45
    • 84902208232 scopus 로고    scopus 로고
    • The International Cancer Genome Consortium's evolving data-protection policies
    • Milius D, Dove ES, Chalmers D, Dyke SO, Kato K, Nicolas P, et al. The International Cancer Genome Consortium's evolving data-protection policies. Nat Biotechnol. 2014;32:519-23.
    • (2014) Nat Biotechnol , vol.32 , pp. 519-523
    • Milius, D.1    Dove, E.S.2    Chalmers, D.3    Dyke, S.O.4    Kato, K.5    Nicolas, P.6
  • 46
    • 84873033894 scopus 로고    scopus 로고
    • Genetic discrimination and life insurance: a systematic review of the evidence
    • Joly Y, Ngueng Feze I, Simard J. Genetic discrimination and life insurance: a systematic review of the evidence. BMC Med. 2013;11:25.
    • (2013) BMC Med , vol.11 , pp. 25
    • Joly, Y.1    Ngueng Feze, I.2    Simard, J.3
  • 47
    • 84889067060 scopus 로고    scopus 로고
    • Reflections on the cost of 'low-cost' whole genome sequencing: framing the health policy debate
    • Caulfield T, Evans J, McGuire A, McCabe C, Bubela T, Cook-Deegan R, et al. Reflections on the cost of 'low-cost' whole genome sequencing: framing the health policy debate. PLoS Biol. 2013;11:e1001699.
    • (2013) PLoS Biol , vol.11 , pp. e1001699
    • Caulfield, T.1    Evans, J.2    McGuire, A.3    McCabe, C.4    Bubela, T.5    Cook-Deegan, R.6
  • 48
    • 34147149098 scopus 로고    scopus 로고
    • Factors associated with an individual's decision to withdraw from genetic testing for breast and ovarian cancer susceptibility: implications for counseling
    • Godard B, Pratte A, Dumont M, Simard-Lebrun A, Simard J. Factors associated with an individual's decision to withdraw from genetic testing for breast and ovarian cancer susceptibility: implications for counseling. Genet Test. 2007;11:45-54.
    • (2007) Genet Test , vol.11 , pp. 45-54
    • Godard, B.1    Pratte, A.2    Dumont, M.3    Simard-Lebrun, A.4    Simard, J.5
  • 49
    • 84904100925 scopus 로고    scopus 로고
    • Office of the Privacy Commissioner of Canada Ottawa, Canada. Accessed 1 July 2015.
    • Phoenix Strategic Perspectives Inc. Survey of Canadians on privacy-related issues. Office of the Privacy Commissioner of Canada Ottawa, Canada. 2013. https://www.priv.gc.ca/information/por-rop/2013/por_2013_01_e.asp Accessed 1 July 2015.
    • (2013) Survey of Canadians on privacy-related issues
  • 50
    • 77952307453 scopus 로고    scopus 로고
    • Is uptake of genetic testing for colorectal cancer influenced by knowledge of insurance implications?
    • Keogh LA, van Vliet CM, Studdert DM, Maskiell JA, Macrae FA, St John DJ, et al. Is uptake of genetic testing for colorectal cancer influenced by knowledge of insurance implications? Med J Aust. 2009;191:255-8.
    • (2009) Med J Aust , vol.191 , pp. 255-258
    • Keogh, L.A.1    Vliet, C.M.2    Studdert, D.M.3    Maskiell, J.A.4    Macrae, F.A.5    St John, D.J.6
  • 51
    • 84866556451 scopus 로고    scopus 로고
    • Unravelling fears of genetic discrimination: an exploratory study of Dutch HCM families in an era of genetic non-discrimination acts
    • Geelen E, Horstman K, Marcelis CL, Doevendans PA, Van Hoyweghen I. Unravelling fears of genetic discrimination: an exploratory study of Dutch HCM families in an era of genetic non-discrimination acts. Eur J Hum Genet. 2012;20:1018-23.
    • (2012) Eur J Hum Genet , vol.20 , pp. 1018-1023
    • Geelen, E.1    Horstman, K.2    Marcelis, C.L.3    Doevendans, P.A.4    Hoyweghen, I.5
  • 52
    • 33746921634 scopus 로고    scopus 로고
    • The personal genome project
    • 2005.0030
    • Church GM. The personal genome project. Mol Syst Biol. 2005;1:2005.0030.
    • (2005) Mol Syst Biol , vol.1
    • Church, G.M.1
  • 56
    • 67649395905 scopus 로고    scopus 로고
    • The ghost in our genes: legal and ethical implications of epigenetics
    • Rothstein MA, Cai Y, Marchant GE. The ghost in our genes: legal and ethical implications of epigenetics. Health Matrix Clevel. 2009;19:1-62.
    • (2009) Health Matrix Clevel , vol.19 , pp. 1-62
    • Rothstein, M.A.1    Cai, Y.2    Marchant, G.E.3
  • 57
    • 84885135978 scopus 로고    scopus 로고
    • Epigenetic exceptionalism
    • Rothstein MA. Epigenetic exceptionalism. J Law Med Ethics. 2013;41:733-6.
    • (2013) J Law Med Ethics , vol.41 , pp. 733-736
    • Rothstein, M.A.1
  • 58
    • 84937227661 scopus 로고    scopus 로고
    • The Genetic Information Nondiscrimination Act (GINA) of 2008
    • Accessed 1 July 2015.
    • U.S. Equal Employment Opportunity Commission. The Genetic Information Nondiscrimination Act (GINA) of 2008. Section 201(7). http://www.eeoc.gov/laws/statutes/gina.cfm Accessed 1 July 2015.
    • Section , vol.201 , Issue.7
  • 59
    • 84864628956 scopus 로고    scopus 로고
    • Data sharing in the post-genomic world: the experience of the International Cancer Genome Consortium (ICGC) Data Access Compliance Office (DACO)
    • Joly Y, Dove ES, Knoppers BM, Bobrow M, Chalmers D. Data sharing in the post-genomic world: the experience of the International Cancer Genome Consortium (ICGC) Data Access Compliance Office (DACO). PLoS Comput Biol. 2012;8:e1002549.
    • (2012) PLoS Comput Biol , vol.8 , pp. e1002549
    • Joly, Y.1    Dove, E.S.2    Knoppers, B.M.3    Bobrow, M.4    Chalmers, D.5
  • 60
    • 84986333488 scopus 로고    scopus 로고
    • Methylation array data can simultaneously identify individuals and convey protected health information: an unrecognized ethical concern
    • Philibert RA, Terry N, Erwin C, Philibert WJ, Beach SRH, Brody GH. Methylation array data can simultaneously identify individuals and convey protected health information: an unrecognized ethical concern. Clin Epigenet. 2014;6:28.
    • (2014) Clin Epigenet , vol.6 , pp. 28
    • Philibert, R.A.1    Terry, N.2    Erwin, C.3    Philibert, W.J.4    Beach, S.R.H.5    Brody, G.H.6
  • 61
    • 84937227662 scopus 로고    scopus 로고
    • Accessed 1 July 2015.
    • NIH Roadmap Epigenomics Project GEO Repository. ftp://ftp.ncbi.nlm.nih.gov/pub/geo/DATA/roadmapepigenomics/by_experiment/Bisulfite-Seq/ Accessed 1 July 2015.
  • 63
    • 84868134071 scopus 로고    scopus 로고
    • Single nucleotide analysis of cytosine methylation by whole-genome shotgun bisulfite sequencing
    • Chapter 21, Unit21.23
    • Johnson MD, Mueller M, Game L, Aitman TJ. Single nucleotide analysis of cytosine methylation by whole-genome shotgun bisulfite sequencing. Curr Protoc Mol Biol. 2012;Chapter 21:Unit21.23.
    • (2012) Curr Protoc Mol Biol
    • Johnson, M.D.1    Mueller, M.2    Game, L.3    Aitman, T.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.