Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses

Science Signaling

Volumn 7, Issue 309, 2014, Pages

  Maruyama, Takeshi ^a   Araki, Toshihiro ^a   Kawarazaki, Yosuke ^a   Naguro, Isao ^a   Heynen, Susanne ^b   Aza Blanc, Pedro ^b   Ronai, Ze'ev ^b   Matsuzawa, Atsushi ^a   Ichijo, Hidenori ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 14; REACTIVE OXYGEN METABOLITE; ROQUIN 2; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; MAP3K5 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; REPRESSOR PROTEIN; ROQUIN 2, HUMAN; ROQUIN-2, HUMAN; UBIQUITIN;

ARTICLE; CAENORHABDITIS ELEGANS; CELL DEATH; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DEFENSE MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE MUTATION; HELA CELL; IMMUNE RESPONSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PSEUDOMONAS INFECTION; UBIQUITINATION; ANIMAL; CELL LINE; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

ANIMALS; CAENORHABDITIS ELEGANS; CELL DEATH; CELL LINE; ENZYME ACTIVATION; HUMANS; HYDROGEN PEROXIDE; MAP KINASE KINASE KINASE 5; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PROTEOLYSIS; REACTIVE OXYGEN SPECIES; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; UBIQUITIN; UBIQUITINATION;

EID: 84893134469     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2004822     Document Type: Article

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