Palmitate induces cisternal ER expansion via the activation of XBP-1/CCTα-mediated phospholipid accumulation in RAW 264.7 cells

Lipids in Health and Disease

Volumn 14, Issue 1, 2015, Pages

  Kim, Seong Keun ^a   Oh, Eunhye ^a   Yun, Mihee ^a   Lee, Seong Beom ^a   Chae, Gue Tae ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

CCT ; ER expansion; Palmitate; Phospholipid accumulation; RAW 264.7 cell; XBP 1

Indexed keywords

4 PHENYLBUTYRIC ACID; CHOLINE CYTIDYLYLTRANSFERASE ALPHA; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; NUCLEOTIDYLTRANSFERASE; PALMITIC ACID; PHOSPHOLIPID; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; DNA BINDING PROTEIN; REGULATORY FACTOR X TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; TUNICAMYCIN; XBP1 PROTEIN, HUMAN; XBP1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CCTA GENE; CELL DEATH; CELL EXPANSION; CISTERNAL ENDOPLASMIC RETICULUM EXPANSION; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME PHOSPHORYLATION; GENE EXPRESSION; LIPID STORAGE; MACROPHAGE; MOUSE; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PROTEIN EXPRESSION; RNA SPLICING; ANIMAL; DRUG EFFECTS; ENDOPLASMIC RETICULUM; METABOLISM; NECROSIS; RAW 264.7 CELL LINE; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

ANIMALS; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE; DNA-BINDING PROTEINS; DOWN-REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; MICE; NECROSIS; PALMITIC ACID; PHOSPHOLIPIDS; RAW 264.7 CELLS; REGULATORY FACTOR X TRANSCRIPTION FACTORS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUNICAMYCIN; X-BOX BINDING PROTEIN 1;

EID: 84937036039     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/s12944-015-0077-3     Document Type: Article

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