메뉴 건너뛰기




Volumn 16, Issue 9, 2015, Pages 997-1013

BDNF/TRKB/P75NTR polymorphisms and their consequences on antidepressant efficacy in depressed patients

Author keywords

antidepressant remission; antidepressant response; BDNF; major depressive disorder; major depressive episode; PNTR75; single nucleotide polymorphism; TRKB

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CITALOPRAM; DESIPRAMINE; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; IMIPRAMINE; LOFEPRAMINE; METHIONINE; MIRTAZAPINE; NEUROTROPHIN RECEPTOR P75; SEROTONIN UPTAKE INHIBITOR; VALINE; VENLAFAXINE; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN; MEMBRANE PROTEIN; NERVE GROWTH FACTOR RECEPTOR; NERVE PROTEIN; NGFR PROTEIN, HUMAN; PROTEIN TYROSINE KINASE; TROPOMYOSIN-RELATED KINASE-B, HUMAN;

EID: 84937000611     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.15.56     Document Type: Review
Times cited : (37)

References (92)
  • 1
    • 30044433660 scopus 로고    scopus 로고
    • Evaluation of outcomes with citalopram for depression using measurement-based care in STARD: Implications for clinical practice
    • Trivedi MH, Rush AJ, Wisniewski SR et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STARD: implications for clinical practice. Am. J. Psychiatry 163(1), 28-40 (2006).
    • (2006) Am. J. Psychiatry , vol.163 , Issue.1 , pp. 28-40
    • Trivedi, M.H.1    Rush, A.J.2    Wisniewski, S.R.3
  • 2
    • 84858440408 scopus 로고    scopus 로고
    • Major depressive disorder: New clinical, neurobiological, and treatment perspectives
    • Kupfer DJ, Frank E, Phillips ML. Major depressive disorder: new clinical, neurobiological, and treatment perspectives. Lancet 379(9820), 1045-1055 (2012).
    • (2012) Lancet , vol.379 , Issue.9820 , pp. 1045-1055
    • Kupfer, D.J.1    Frank, E.2    Phillips, M.L.3
  • 3
    • 65649125633 scopus 로고    scopus 로고
    • Neurogenesis-dependent and-independent effects of fluoxetine in an animal model of anxiety/depression
    • David DJ, Samuels BA, Rainer Q et al. Neurogenesis-dependent and-independent effects of fluoxetine in an animal model of anxiety/depression. Neuron 62(4), 479-493 (2009).
    • (2009) Neuron , vol.62 , Issue.4 , pp. 479-493
    • David, D.J.1    Samuels, B.A.2    Rainer, Q.3
  • 4
    • 81755172044 scopus 로고    scopus 로고
    • Antidepressants recruit new neurons to improve stress response regulation
    • Surget A, Tanti A, Leonardo ED et al. Antidepressants recruit new neurons to improve stress response regulation. Mol. Psychiatry 16(12), 1177-1188 (2011).
    • (2011) Mol. Psychiatry , vol.16 , Issue.12 , pp. 1177-1188
    • Surget, A.1    Tanti, A.2    Leonardo, E.D.3
  • 5
    • 84907483716 scopus 로고    scopus 로고
    • The current state of the neurogenic theory of depression and anxiety
    • Miller BR, Hen R. The current state of the neurogenic theory of depression and anxiety. Curr. Opin. Neurobiol. 30C, 51-58 (2015).
    • (2015) Curr. Opin. Neurobiol. , vol.30 C , pp. 51-58
    • Miller, B.R.1    Hen, R.2
  • 6
    • 84922257150 scopus 로고    scopus 로고
    • Adult neurogenesis in humans-common and unique traits in mammals
    • Ernst A, Frisen J. Adult neurogenesis in humans-common and unique traits in mammals. PLoS Biol. 13(1), e1002045 (2015).
    • (2015) PLoS Biol. , vol.13 , Issue.1 , pp. e1002045
    • Ernst, A.1    Frisen, J.2
  • 7
    • 0020338405 scopus 로고
    • Purification of a new neurotrophic factor from mammalian brain
    • Barde YA, Edgar D, Thoenen H. Purification of a new neurotrophic factor from mammalian brain. EMBO J. 1(5), 549-553 (1982).
    • (1982) EMBO J. , vol.1 , Issue.5 , pp. 549-553
    • Barde, Y.A.1    Edgar, D.2    Thoenen, H.3
  • 8
    • 34547499702 scopus 로고    scopus 로고
    • Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters
    • Pruunsild P, Kazantseva A, Aid T, Palm K, Timmusk T. Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics 90(3), 397-406 (2007).
    • (2007) Genomics , vol.90 , Issue.3 , pp. 397-406
    • Pruunsild, P.1    Kazantseva, A.2    Aid, T.3    Palm, K.4    Timmusk, T.5
  • 9
    • 0041379342 scopus 로고    scopus 로고
    • Pro-region of neurotrophins: Role in synaptic modulation
    • Lu B. Pro-region of neurotrophins: role in synaptic modulation. Neuron 39(5), 735-738 (2003).
    • (2003) Neuron , vol.39 , Issue.5 , pp. 735-738
    • Lu, B.1
  • 10
    • 0012315645 scopus 로고    scopus 로고
    • Neurotrophin secretion: Current facts and future prospects
    • Lessmann V, Gottmann K, Malcangio M. Neurotrophin secretion: current facts and future prospects. Prog. Neurobiol. 69(5), 341-374 (2003).
    • (2003) Prog. Neurobiol. , vol.69 , Issue.5 , pp. 341-374
    • Lessmann, V.1    Gottmann, K.2    Malcangio, M.3
  • 11
    • 0036344505 scopus 로고    scopus 로고
    • Neurotrophin signaling through the p75 neurotrophin receptor
    • Roux PP, Barker PA. Neurotrophin signaling through the p75 neurotrophin receptor. Prog. Neurobiol. 67(3), 203-233 (2002).
    • (2002) Prog. Neurobiol. , vol.67 , Issue.3 , pp. 203-233
    • Roux, P.P.1    Barker, P.A.2
  • 12
    • 77949746666 scopus 로고    scopus 로고
    • The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity
    • Castren E, Rantamaki T. The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity. Dev. Neurobiol. 70(5), 289-297 (2010).
    • (2010) Dev. Neurobiol. , vol.70 , Issue.5 , pp. 289-297
    • Castren, E.1    Rantamaki, T.2
  • 13
    • 0028090302 scopus 로고
    • The Trk family of neurotrophin receptors
    • Barbacid M. The Trk family of neurotrophin receptors. J. Neurobiol. 25(11), 1386-1403 (1994).
    • (1994) J. Neurobiol. , vol.25 , Issue.11 , pp. 1386-1403
    • Barbacid, M.1
  • 14
    • 70450224435 scopus 로고    scopus 로고
    • The lamellar cells in human Meissner corpuscles express TrkB
    • Calavia MG, Feito J, Lopez-Iglesias L et al. The lamellar cells in human Meissner corpuscles express TrkB. Neurosci. Lett. 468(2), 106-109 (2010).
    • (2010) Neurosci. Lett. , vol.468 , Issue.2 , pp. 106-109
    • Calavia, M.G.1    Feito, J.2    Lopez-Iglesias, L.3
  • 15
    • 0028951557 scopus 로고
    • Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2)
    • Nakagawara A, Liu XG, Ikegaki N et al. Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2). Genomics 25(2), 538-546 (1995).
    • (1995) Genomics , vol.25 , Issue.2 , pp. 538-546
    • Nakagawara, A.1    Liu, X.G.2    Ikegaki, N.3
  • 16
    • 70450222707 scopus 로고    scopus 로고
    • Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: Association with major depression and antidepressant response in Mexican-Americans
    • Dong C, Wong ML, Licinio J. Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans. Mol. Psychiatry 14(12), 1105-1118 (2009).
    • (2009) Mol. Psychiatry , vol.14 , Issue.12 , pp. 1105-1118
    • Dong, C.1    Wong, M.L.2    Licinio, J.3
  • 17
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan DR, Miller FD. Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10(3), 381-391 (2000).
    • (2000) Curr. Opin. Neurobiol. , vol.10 , Issue.3 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 18
    • 23044488902 scopus 로고    scopus 로고
    • The yin and yang of neurotrophin action
    • Lu B, Pang PT, Woo NH. The yin and yang of neurotrophin action. Nat. Rev. Neurosci. 6(8), 603-614 (2005).
    • (2005) Nat. Rev. Neurosci. , vol.6 , Issue.8 , pp. 603-614
    • Lu, B.1    Pang, P.T.2    Woo, N.H.3
  • 19
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman RS, Monteggia LM. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry 59(12), 1116-1127 (2006).
    • (2006) Biol. Psychiatry , vol.59 , Issue.12 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 20
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J. Neurosci. 22(8), 3251-3261 (2002).
    • (2002) J. Neurosci. , vol.22 , Issue.8 , pp. 3251-3261
    • Shirayama, Y.1    Chen, A.C.2    Nakagawa, S.3    Russell, D.S.4    Duman, R.S.5
  • 21
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M, Morinobu S, Duman RS. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J. Neurosci. 15(11), 7539-7547 (1995).
    • (1995) J. Neurosci. , vol.15 , Issue.11 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 22
    • 84863380672 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants
    • Yu H, Wang DD, Wang Y, Liu T, Lee FS, Chen ZY. Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants. J. Neurosci. 32(12), 4092-4101 (2012).
    • (2012) J. Neurosci. , vol.32 , Issue.12 , pp. 4092-4101
    • Yu, H.1    Wang, D.D.2    Wang, Y.3    Liu, T.4    Lee, F.S.5    Chen, Z.Y.6
  • 23
    • 35348849104 scopus 로고    scopus 로고
    • Chronic duloxetine treatment induces specific changes in the expression of BDNF transcripts and in the subcellular localization of the neurotrophin protein
    • Calabrese F, Molteni R, Maj PF et al. Chronic duloxetine treatment induces specific changes in the expression of BDNF transcripts and in the subcellular localization of the neurotrophin protein. Neuropsychopharmacology 32(11), 2351-2359 (2007).
    • (2007) Neuropsychopharmacology , vol.32 , Issue.11 , pp. 2351-2359
    • Calabrese, F.1    Molteni, R.2    Maj, P.F.3
  • 24
    • 67949109533 scopus 로고    scopus 로고
    • Venlafaxine treatment stimulates expression of brain-derived neurotrophic factor protein in frontal cortex and inhibits long-term potentiation in hippocampus
    • Cooke JD, Grover LM, Spangler PR. Venlafaxine treatment stimulates expression of brain-derived neurotrophic factor protein in frontal cortex and inhibits long-term potentiation in hippocampus. Neuroscience 162(4), 1411-1419 (2009).
    • (2009) Neuroscience , vol.162 , Issue.4 , pp. 1411-1419
    • Cooke, J.D.1    Grover, L.M.2    Spangler, P.R.3
  • 25
    • 80052563683 scopus 로고    scopus 로고
    • Vulnerability to depression: From brain neuroplasticity to identification of biomarkers
    • Blugeot A, Rivat C, Bouvier E et al. Vulnerability to depression: from brain neuroplasticity to identification of biomarkers. J. Neurosci. 31(36), 12889-12899 (2011).
    • (2011) J. Neurosci. , vol.31 , Issue.36 , pp. 12889-12899
    • Blugeot, A.1    Rivat, C.2    Bouvier, E.3
  • 26
    • 79958150004 scopus 로고    scopus 로고
    • Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade
    • Rantamaki T, Vesa L, Antila H et al. Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade. PLoS ONE 6(6), e20567 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.6 , pp. e20567
    • Rantamaki, T.1    Vesa, L.2    Antila, H.3
  • 27
    • 48749115329 scopus 로고    scopus 로고
    • TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment
    • Li Y, Luikart BW, Birnbaum S et al. TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron 59(3), 399-412 (2008).
    • (2008) Neuron , vol.59 , Issue.3 , pp. 399-412
    • Li, Y.1    Luikart, B.W.2    Birnbaum, S.3
  • 28
    • 84867352628 scopus 로고    scopus 로고
    • Optimization of a small tropomyosin-related kinase B (TrkB) agonist 7. 8-dihydroxyflavone active in mouse models of depression
    • Liu X, Chan CB, Qi Q et al. Optimization of a small tropomyosin-related kinase B (TrkB) agonist 7, 8-dihydroxyflavone active in mouse models of depression. J. Med. Chem. 55(19), 8524-8537 (2012).
    • (2012) J. Med. Chem. , vol.55 , Issue.19 , pp. 8524-8537
    • Liu, X.1    Chan, C.B.2    Qi, Q.3
  • 29
    • 58349088923 scopus 로고    scopus 로고
    • Neurotrophin receptor activation and expression in human postmortem brain: Effect of suicide
    • Dwivedi Y, Rizavi HS, Zhang H et al. Neurotrophin receptor activation and expression in human postmortem brain: effect of suicide. Biol. Psychiatry 65(4), 319-328 (2009).
    • (2009) Biol. Psychiatry , vol.65 , Issue.4 , pp. 319-328
    • Dwivedi, Y.1    Rizavi, H.S.2    Zhang, H.3
  • 30
    • 33845635596 scopus 로고    scopus 로고
    • Low plasma BDNF is associated with suicidal behavior in major depression
    • Kim YK, Lee HP, Won SD et al. Low plasma BDNF is associated with suicidal behavior in major depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 31(1), 78-85 (2007).
    • (2007) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.31 , Issue.1 , pp. 78-85
    • Kim, Y.K.1    Lee, H.P.2    Won, S.D.3
  • 31
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • Chen B, Dowlatshahi D, Macqueen GM, Wang JF, Young LT. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol. Psychiatry 50(4), 260-265 (2001).
    • (2001) Biol. Psychiatry , vol.50 , Issue.4 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    Macqueen, G.M.3    Wang, J.F.4    Young, L.T.5
  • 32
    • 49749101642 scopus 로고    scopus 로고
    • Serum brain-derived neurotrophic factor, depression, and antidepressant medications: Meta-analyses and implications
    • Sen S, Duman R, Sanacora G. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol. Psychiatry 64(6), 527-532 (2008).
    • (2008) Biol. Psychiatry , vol.64 , Issue.6 , pp. 527-532
    • Sen, S.1    Duman, R.2    Sanacora, G.3
  • 33
    • 84903584769 scopus 로고    scopus 로고
    • Serum BDNF concentrations as peripheral manifestations of depression: Evidence from a systematic review and meta-analyses on 179 associations (N=9484)
    • Molendijk ML, Spinhoven P, Polak M, Bus BA, Penninx BW, Elzinga BM. Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484). Mol. Psychiatry 19(7), 791-800 (2014).
    • (2014) Mol. Psychiatry , vol.19 , Issue.7 , pp. 791-800
    • Molendijk, M.L.1    Spinhoven, P.2    Polak, M.3    Bus, B.A.4    Penninx, B.W.5    Elzinga, B.M.6
  • 34
    • 0142219372 scopus 로고    scopus 로고
    • Association study of a brain-derived neurotrophic-factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response
    • Tsai SJ, Cheng CY, Yu YW, Chen TJ, Hong CJ. Association study of a brain-derived neurotrophic-factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response. Am. J. Med. Genet. B Neuropsychiatr. Genet. 123B(1), 19-22 (2003).
    • (2003) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.123 B , Issue.1 , pp. 19-22
    • Tsai, S.J.1    Cheng, C.Y.2    Yu, Y.W.3    Chen, T.J.4    Hong, C.J.5
  • 35
    • 33750371336 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder
    • Choi MJ, Kang RH, Lim SW, Oh KS, Lee MS. Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder. Brain Res. 1118(1), 176-182 (2006).
    • (2006) Brain Res. , vol.1118 , Issue.1 , pp. 176-182
    • Choi, M.J.1    Kang, R.H.2    Lim, S.W.3    Oh, K.S.4    Lee, M.S.5
  • 36
    • 34247576658 scopus 로고    scopus 로고
    • A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression
    • Wilkie MJ, Smith D, Reid IC et al. A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression. Pharmacogenet. Genomics 17(3), 207-215 (2007).
    • (2007) Pharmacogenet. Genomics , vol.17 , Issue.3 , pp. 207-215
    • Wilkie, M.J.1    Smith, D.2    Reid, I.C.3
  • 37
    • 40949152013 scopus 로고    scopus 로고
    • A brain-derived neurotrophic factor (BDNF) haplotype is associated with antidepressant treatment outcome in mood disorders
    • Gratacos M, Soria V, Urretavizcaya M et al. A brain-derived neurotrophic factor (BDNF) haplotype is associated with antidepressant treatment outcome in mood disorders. Pharmacogenomics J. 8(2), 101-112 (2008).
    • (2008) Pharmacogenomics J. , vol.8 , Issue.2 , pp. 101-112
    • Gratacos, M.1    Soria, V.2    Urretavizcaya, M.3
  • 38
    • 69549111780 scopus 로고    scopus 로고
    • Association study of a brain-derived neurotrophic-factor polymorphism and short-term antidepressant response in major depressive disorders
    • Lin E, Chen PS, Huang LC, Hsu SY. Association study of a brain-derived neurotrophic-factor polymorphism and short-term antidepressant response in major depressive disorders. Pharmgenomics Pers. Med. 1, 1-6 (2008).
    • (2008) Pharmgenomics Pers. Med. , vol.1 , pp. 1-6
    • Lin, E.1    Chen, P.S.2    Huang, L.C.3    Hsu, S.Y.4
  • 39
    • 34249317809 scopus 로고    scopus 로고
    • The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine
    • Yoshida K, Higuchi H, Kamata M et al. The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine. J. Psychopharmacol. 21(6), 650-656 (2007).
    • (2007) J. Psychopharmacol. , vol.21 , Issue.6 , pp. 650-656
    • Yoshida, K.1    Higuchi, H.2    Kamata, M.3
  • 40
    • 46949110138 scopus 로고    scopus 로고
    • Evidence for association between genetic variants of p75 neurotrophin receptor (p75NTR) gene and antidepressant treatment response in Chinese major depressive disorder
    • Gau YT, Liou YJ, Yu YW et al. Evidence for association between genetic variants of p75 neurotrophin receptor (p75NTR) gene and antidepressant treatment response in Chinese major depressive disorder. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B(5), 594-599 (2008).
    • (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.147 B , Issue.5 , pp. 594-599
    • Gau, Y.T.1    Liou, Y.J.2    Yu, Y.W.3
  • 41
    • 65549105390 scopus 로고    scopus 로고
    • Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response
    • Licinio J, Dong C, Wong ML. Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response. Arch. Gen. Psychiatry 66(5), 488-497 (2009).
    • (2009) Arch. Gen. Psychiatry , vol.66 , Issue.5 , pp. 488-497
    • Licinio, J.1    Dong, C.2    Wong, M.L.3
  • 42
    • 77955553377 scopus 로고    scopus 로고
    • BDNF val66met polymorphism, white matter abnormalities and remission of geriatric depression
    • Alexopoulos GS, Glatt CE, Hoptman MJ et al. BDNF val66met polymorphism, white matter abnormalities and remission of geriatric depression. J. Affect. Disord. 125(1-3), 262-268 (2010).
    • (2010) J. Affect. Disord. , vol.125 , Issue.1-3 , pp. 262-268
    • Alexopoulos, G.S.1    Glatt, C.E.2    Hoptman, M.J.3
  • 43
    • 77950297985 scopus 로고    scopus 로고
    • No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment
    • Bukh JD, Bock C, Vinberg M, Werge T, Gether U, Kessing LV. No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment. Eur. Neuropsychopharmacol. 20(5), 327-335 (2010).
    • (2010) Eur. Neuropsychopharmacol. , vol.20 , Issue.5 , pp. 327-335
    • Bukh, J.D.1    Bock, C.2    Vinberg, M.3    Werge, T.4    Gether, U.5    Kessing, L.V.6
  • 44
    • 77949580959 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) gene: No major impact on antidepressant treatment response
    • Domschke K, Lawford B, Laje G et al. Brain-derived neurotrophic factor (BDNF) gene: no major impact on antidepressant treatment response. Int. J. Neuropsychopharmacol. 13(1), 93-101 (2010).
    • (2010) Int. J. Neuropsychopharmacol. , vol.13 , Issue.1 , pp. 93-101
    • Domschke, K.1    Lawford, B.2    Laje, G.3
  • 45
    • 78650079772 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene polymorphisms and mirtazapine responses in Koreans with major depression
    • Kang RH, Chang HS, Wong ML et al. Brain-derived neurotrophic factor gene polymorphisms and mirtazapine responses in Koreans with major depression. J. Psychopharmacol. 24(12), 1755-1763 (2010).
    • (2010) J. Psychopharmacol. , vol.24 , Issue.12 , pp. 1755-1763
    • Kang, R.H.1    Chang, H.S.2    Wong, M.L.3
  • 46
    • 77953628065 scopus 로고    scopus 로고
    • Genetic predictors of response to treatment with citalopram in depression secondary to traumatic brain injury
    • Lanctot KL, Rapoport MJ, Chan F et al. Genetic predictors of response to treatment with citalopram in depression secondary to traumatic brain injury. Brain Inj. 24(7-8), 959-969 (2010).
    • (2010) Brain Inj. , vol.24 , Issue.7-8 , pp. 959-969
    • Lanctot, K.L.1    Rapoport, M.J.2    Chan, F.3
  • 47
    • 84980053687 scopus 로고    scopus 로고
    • Influence of BDNF variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia
    • Pae CU, Chiesa A, Porcelli S et al. Influence of BDNF variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia. Neuropsychobiology 65(1), 1-11 (2012).
    • (2012) Neuropsychobiology , vol.65 , Issue.1 , pp. 1-11
    • Pae, C.U.1    Chiesa, A.2    Porcelli, S.3
  • 48
    • 72049090168 scopus 로고    scopus 로고
    • Association of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patients
    • Zou YF, Wang Y, Liu P et al. Association of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patients. Neuropsychobiology 61(2), 71-78 (2010).
    • (2010) Neuropsychobiology , vol.61 , Issue.2 , pp. 71-78
    • Zou, Y.F.1    Wang, Y.2    Liu, P.3
  • 49
    • 78650814423 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene polymorphisms: Influence on treatment response phenotypes of major depressive disorder
    • Kocabas NA, Antonijevic I, Faghel C et al. Brain-derived neurotrophic factor gene polymorphisms: influence on treatment response phenotypes of major depressive disorder. Int. Clin. Psychopharmacol. 26(1), 1-10 (2011).
    • (2011) Int. Clin. Psychopharmacol. , vol.26 , Issue.1 , pp. 1-10
    • Kocabas, N.A.1    Antonijevic, I.2    Faghel, C.3
  • 50
    • 80052839502 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor is associated with alcohol dependence-related depression and antidepressant response
    • Su N, Zhang L, Fei F et al. The brain-derived neurotrophic factor is associated with alcohol dependence-related depression and antidepressant response. Brain Res. 1415, 119-126 (2011).
    • (2011) Brain Res. , vol.1415 , pp. 119-126
    • Su, N.1    Zhang, L.2    Fei, F.3
  • 51
    • 79953031271 scopus 로고    scopus 로고
    • BDNF Val66Met genotype and 6-month remission rates in late-life depression
    • Taylor WD, Mcquoid DR, Ashley-Koch A et al. BDNF Val66Met genotype and 6-month remission rates in late-life depression. Pharmacogenomics J. 11(2), 146-154 (2011).
    • (2011) Pharmacogenomics J. , vol.11 , Issue.2 , pp. 146-154
    • Taylor, W.D.1    McQuoid, D.R.2    Ashley-Koch, A.3
  • 52
    • 79956009846 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor (BDNF) polymorphism Val66Met is associated with neither serum BDNF level nor response to selective serotonin reuptake inhibitors in depressed Japanese patients
    • Yoshimura R, Kishi T, Suzuki A et al. The brain-derived neurotrophic factor (BDNF) polymorphism Val66Met is associated with neither serum BDNF level nor response to selective serotonin reuptake inhibitors in depressed Japanese patients. Prog. Neuropsychopharmacol. Biol. Psychiatry 35(4), 1022-1025 (2011).
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , Issue.4 , pp. 1022-1025
    • Yoshimura, R.1    Kishi, T.2    Suzuki, A.3
  • 53
    • 84869232094 scopus 로고    scopus 로고
    • Serum levels of brain-derived neurotrophic factor (BDNF), BDNF gene Val66Met polymorphism, or plasma catecholamine metabolites, and response to mirtazapine in Japanese patients with major depressive disorder (MDD)
    • Katsuki A, Yoshimura R, Kishi T et al. Serum levels of brain-derived neurotrophic factor (BDNF), BDNF gene Val66Met polymorphism, or plasma catecholamine metabolites, and response to mirtazapine in Japanese patients with major depressive disorder (MDD). CNS Spectr. 17(3), 155-163 (2012).
    • (2012) CNS Spectr. , vol.17 , Issue.3 , pp. 155-163
    • Katsuki, A.1    Yoshimura, R.2    Kishi, T.3
  • 54
    • 84881314342 scopus 로고    scopus 로고
    • No influence of brain-derived neurotrophic factor (BDNF) polymorphisms on treatment response in a naturalistic sample of patients with major depression
    • Musil R, Zill P, Seemuller F et al. No influence of brain-derived neurotrophic factor (BDNF) polymorphisms on treatment response in a naturalistic sample of patients with major depression. Eur. Arch. Psychiatry Clin. Neurosci. 263(5), 405-412 (2013).
    • (2013) Eur. Arch. Psychiatry Clin. Neurosci. , vol.263 , Issue.5 , pp. 405-412
    • Musil, R.1    Zill, P.2    Seemuller, F.3
  • 55
    • 84863422630 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene polymorphism (Val66Met) and the early response to antidepressant in Chinese Han population
    • Xu G, Lin K, Rao D et al. Brain-derived neurotrophic factor gene polymorphism (Val66Met) and the early response to antidepressant in Chinese Han population. Psychiatr. Genet. 22(4), 214-215 (2012).
    • (2012) Psychiatr. Genet. , vol.22 , Issue.4 , pp. 214-215
    • Xu, G.1    Lin, K.2    Rao, D.3
  • 56
    • 84878653433 scopus 로고    scopus 로고
    • Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: Findings from an extended tag SNP approach
    • Hennings JM, Kohli MA, Czamara D et al. Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach. PLoS ONE 8(6), e64947 (2013).
    • (2013) PLoS ONE , vol.8 , Issue.6 , pp. e64947
    • Hennings, J.M.1    Kohli, M.A.2    Czamara, D.3
  • 57
    • 84871771037 scopus 로고    scopus 로고
    • No support for a role for BDNF gene polymorphisms rs11030101 and rs61888800 in major depressive disorder or antidepressant response in patients of Finnish origin
    • Illi A, Viikki M, Poutanen O et al. No support for a role for BDNF gene polymorphisms rs11030101 and rs61888800 in major depressive disorder or antidepressant response in patients of Finnish origin. Psychiatr. Genet. 23(1), 33-35 (2013).
    • (2013) Psychiatr. Genet. , vol.23 , Issue.1 , pp. 33-35
    • Illi, A.1    Viikki, M.2    Poutanen, O.3
  • 58
    • 84869878797 scopus 로고    scopus 로고
    • The role of BDNF, NTRK2 gene and their interaction in development of treatment-resistant depression: Data from multicenter, prospective, longitudinal clinic practice
    • Li Z, Zhang Y, Wang Z et al. The role of BDNF, NTRK2 gene and their interaction in development of treatment-resistant depression: data from multicenter, prospective, longitudinal clinic practice. J. Psychiatr. Res. 47(1), 8-14 (2013).
    • (2013) J. Psychiatr. Res. , vol.47 , Issue.1 , pp. 8-14
    • Li, Z.1    Zhang, Y.2    Wang, Z.3
  • 59
    • 84922149634 scopus 로고    scopus 로고
    • The BDNF ValMet polymorphism is associated with escitalopram response in depressed patients
    • El-Hage W, Vourc'h P, Gaillard P et al. The BDNF ValMet polymorphism is associated with escitalopram response in depressed patients. Psychopharmacology 232(3), 575-581 (2014).
    • (2014) Psychopharmacology , vol.232 , Issue.3 , pp. 575-581
    • El-Hage, W.1    Vourc'h, P.2    Gaillard, P.3
  • 60
    • 84914146666 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor gene polymorphisms are associated with coronary artery diseaserelated depression and antidepressant response
    • Liu YQ, Su GB, Duan CH et al. Brainderived neurotrophic factor gene polymorphisms are associated with coronary artery diseaserelated depression and antidepressant response. Mol. Med. Rep. 10(6), 3247-3253 (2014).
    • (2014) Mol. Med. Rep. , vol.10 , Issue.6 , pp. 3247-3253
    • Liu, Y.Q.1    Su, G.B.2    Duan, C.H.3
  • 61
    • 84933048474 scopus 로고    scopus 로고
    • Serotonin transporter gene: A new polymorphism may affect response to antidepressant treatments in major depressive disorder
    • Matsumoto Y, Fabbri C, Pellegrini S et al. Serotonin transporter gene: a new polymorphism may affect response to antidepressant treatments in major depressive disorder. Mol. Diagn. Ther. 18(5), 567-577 (2014).
    • (2014) Mol. Diagn. Ther. , vol.18 , Issue.5 , pp. 567-577
    • Matsumoto, Y.1    Fabbri, C.2    Pellegrini, S.3
  • 62
    • 84964239589 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor Val66Met polymorphism and 6-month antidepressant remission in depressed Caucasian patients
    • Colle R, Gressier F, Verstuyft C et al. Brain-derived neurotrophic factor Val66Met polymorphism and 6-month antidepressant remission in depressed Caucasian patients. J. Affect. Disord. 175C, 233-240 (2015).
    • (2015) J. Affect. Disord. , vol.175 C , pp. 233-240
    • Colle, R.1    Gressier, F.2    Verstuyft, C.3
  • 64
    • 77951779878 scopus 로고    scopus 로고
    • Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    • Uher R, Perroud N, Ng MY et al. Genome-wide pharmacogenetics of antidepressant response in the GENDEP project. Am. J. Psychiatry 167(5), 555-564 (2010).
    • (2010) Am. J. Psychiatry , vol.167 , Issue.5 , pp. 555-564
    • Uher, R.1    Perroud, N.2    Ng, M.Y.3
  • 65
    • 69949184308 scopus 로고    scopus 로고
    • A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    • Ising M, Lucae S, Binder EB et al. A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Arch. Gen. Psychiatry 66(9), 966-975 (2009).
    • (2009) Arch. Gen. Psychiatry , vol.66 , Issue.9 , pp. 966-975
    • Ising, M.1    Lucae, S.2    Binder, E.B.3
  • 66
    • 71649105262 scopus 로고    scopus 로고
    • A genomewide association study of citalopram response in major depressive disorder
    • Garriock HA, Kraft JB, Shyn SI et al. A genomewide association study of citalopram response in major depressive disorder. Biol. Psychiatry 67(2), 133-138 (2010).
    • (2010) Biol. Psychiatry , vol.67 , Issue.2 , pp. 133-138
    • Garriock, H.A.1    Kraft, J.B.2    Shyn, S.I.3
  • 67
    • 84884592615 scopus 로고    scopus 로고
    • Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: Genome-wide associations and functional genomics
    • Ji Y, Biernacka JM, Hebbring S et al. Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics. Pharmacogenomics J. 13(5), 456-463 (2013).
    • (2013) Pharmacogenomics J. , vol.13 , Issue.5 , pp. 456-463
    • Ji, Y.1    Biernacka, J.M.2    Hebbring, S.3
  • 68
    • 84873348443 scopus 로고    scopus 로고
    • Common genetic variation and antidepressant efficacy in major depressive disorder: A meta-analysis of three genome-wide pharmacogenetic studies
    • GENDEP Investigators1; MARS Investigators; STARD Investigators
    • GENDEP Investigators1; MARS Investigators; STARD Investigators. Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. Am. J. Psychiatry 170(2), 207-217 (2013).
    • (2013) Am. J. Psychiatry , vol.170 , Issue.2 , pp. 207-217
  • 69
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    • Egan MF, Kojima M, Callicott JH et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112(2), 257-269 (2003).
    • (2003) Cell , vol.112 , Issue.2 , pp. 257-269
    • Egan, M.F.1    Kojima, M.2    Callicott, J.H.3
  • 70
    • 77951844279 scopus 로고    scopus 로고
    • Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder
    • Kato M, Serretti A. Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder. Mol. Psychiatry 15(5), 473-500 (2010).
    • (2010) Mol. Psychiatry , vol.15 , Issue.5 , pp. 473-500
    • Kato, M.1    Serretti, A.2
  • 71
    • 84922127622 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor Val66Met polymorphism association with antidepressant efficacy: A systematic review and meta-analysis
    • Yan T, Wang L, Kuang W et al. Brain-derived neurotrophic factor Val66Met polymorphism association with antidepressant efficacy: a systematic review and meta-analysis. Asia Pac. Psychiatry 6(3), 241-251 (2014).
    • (2014) Asia Pac. Psychiatry , vol.6 , Issue.3 , pp. 241-251
    • Yan, T.1    Wang, L.2    Kuang, W.3
  • 72
    • 77953962523 scopus 로고    scopus 로고
    • Meta-analysis of BDNF Val66Met polymorphism association with treatment response in patients with major depressive disorder
    • Zou YF, Ye DQ, Feng XL, Su H, Pan FM, Liao FF. Meta-analysis of BDNF Val66Met polymorphism association with treatment response in patients with major depressive disorder. Eur. Neuropsychopharmacol. 20(8), 535-544 (2010).
    • (2010) Eur. Neuropsychopharmacol. , vol.20 , Issue.8 , pp. 535-544
    • Zou, Y.F.1    Ye, D.Q.2    Feng, X.L.3    Su, H.4    Pan, F.M.5    Liao, F.F.6
  • 74
    • 77957336025 scopus 로고    scopus 로고
    • Brain derived neurotrophic factor gene polymorphism (Val66Met) and short-term antidepressant response in major depressive disorder
    • Chi MH, Chang HH, Lee SY et al. Brain derived neurotrophic factor gene polymorphism (Val66Met) and short-term antidepressant response in major depressive disorder. J. Affect. Disord. 126(3), 430-435 (2010).
    • (2010) J. Affect. Disord. , vol.126 , Issue.3 , pp. 430-435
    • Chi, M.H.1    Chang, H.H.2    Lee, S.Y.3
  • 75
    • 68049127796 scopus 로고    scopus 로고
    • Genetic variation in brain-derived neurotrophic factor is associated with serotonin transporter but not serotonin-1A receptor availability in men
    • Henningsson S, Borg J, Lundberg J et al. Genetic variation in brain-derived neurotrophic factor is associated with serotonin transporter but not serotonin-1A receptor availability in men. Biol. Psychiatry 66(5), 477-485 (2009).
    • (2009) Biol. Psychiatry , vol.66 , Issue.5 , pp. 477-485
    • Henningsson, S.1    Borg, J.2    Lundberg, J.3
  • 76
    • 84906957542 scopus 로고    scopus 로고
    • Exploring the impact of BDNF Val66Met genotype on serotonin transporter and serotonin-1A receptor binding
    • Kraus C, Baldinger P, Rami-Mark C et al. Exploring the impact of BDNF Val66Met genotype on serotonin transporter and serotonin-1A receptor binding. PLoS ONE 9(9), e106810 (2014).
    • (2014) PLoS ONE , vol.9 , Issue.9 , pp. e106810
    • Kraus, C.1    Baldinger, P.2    Rami-Mark, C.3
  • 77
    • 84893862320 scopus 로고    scopus 로고
    • From pharmacogenetics to pharmacogenomics: The way toward the personalization of antidepressant treatment
    • Fabbri C, Porcelli S, Serretti A. From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment. Can. J. Psychiatry 59(2), 62-75 (2014).
    • (2014) Can. J. Psychiatry , vol.59 , Issue.2 , pp. 62-75
    • Fabbri, C.1    Porcelli, S.2    Serretti, A.3
  • 78
    • 79961126893 scopus 로고    scopus 로고
    • Genome-wide association studies of antidepressant outcome: A brief review
    • Laje G, Mcmahon FJ. Genome-wide association studies of antidepressant outcome: a brief review. Prog. Neuropsychopharmacol. Biol. Psychiatry 35(7), 1553-1557 (2011).
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , Issue.7 , pp. 1553-1557
    • Laje, G.1    McMahon, F.J.2
  • 79
    • 84903897703 scopus 로고    scopus 로고
    • How to read a systematic review and meta-analysis and apply the results to patient care: Users' guides to the medical literature
    • Murad MH, Montori VM, Ioannidis JP et al. How to read a systematic review and meta-analysis and apply the results to patient care: users' guides to the medical literature. JAMA 312(2), 171-179 (2014).
    • (2014) JAMA , vol.312 , Issue.2 , pp. 171-179
    • Murad, M.H.1    Montori, V.M.2    Ioannidis, J.P.3
  • 80
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • Martinowich K, Hattori D, Wu H et al. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 302(5646), 890-893 (2003).
    • (2003) Science , vol.302 , Issue.5646 , pp. 890-893
    • Martinowich, K.1    Hattori, D.2    Wu, H.3
  • 81
    • 84914106962 scopus 로고    scopus 로고
    • Clinical outcomes and genome-wide association for a brain methylation site in an antidepressant pharmacogenetics study in mexican americans
    • Wong ML, Dong C, Flores DL et al. Clinical outcomes and genome-wide association for a brain methylation site in an antidepressant pharmacogenetics study in mexican americans. Am. J. Psychiatry 171(12), 1297-1309 (2014).
    • (2014) Am. J. Psychiatry , vol.171 , Issue.12 , pp. 1297-1309
    • Wong, M.L.1    Dong, C.2    Flores, D.L.3
  • 82
    • 79955594736 scopus 로고    scopus 로고
    • Child health, developmental plasticity, and epigenetic programming
    • Hochberg Z, Feil R, Constancia M et al. Child health, developmental plasticity, and epigenetic programming. Endocr. Rev. 32(2), 159-224 (2011).
    • (2011) Endocr. Rev. , vol.32 , Issue.2 , pp. 159-224
    • Hochberg, Z.1    Feil, R.2    Constancia, M.3
  • 83
    • 3342989681 scopus 로고    scopus 로고
    • Epigenetic programming by maternal behavior
    • Weaver IC, Cervoni N, Champagne FA et al. Epigenetic programming by maternal behavior. Nat. Neurosci. 7(8), 847-854 (2004).
    • (2004) Nat. Neurosci. , vol.7 , Issue.8 , pp. 847-854
    • Weaver, I.C.1    Cervoni, N.2    Champagne, F.A.3
  • 84
    • 60749105468 scopus 로고    scopus 로고
    • Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
    • Mcgowan PO, Sasaki A, D'Alessio AC et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat. Neurosci. 12(3), 342-348 (2009).
    • (2009) Nat. Neurosci. , vol.12 , Issue.3 , pp. 342-348
    • McGowan, P.O.1    Sasaki, A.2    D'alessio, A.C.3
  • 85
    • 47149100122 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
    • Oberlander TF, Weinberg J, Papsdorf M, Grunau R, Misri S, Devlin AM. Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 3(2), 97-106 (2008).
    • (2008) Epigenetics , vol.3 , Issue.2 , pp. 97-106
    • Oberlander, T.F.1    Weinberg, J.2    Papsdorf, M.3    Grunau, R.4    Misri, S.5    Devlin, A.M.6
  • 86
    • 42349112088 scopus 로고    scopus 로고
    • Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
    • McCarthy MI, Abecasis GR, Cardon LR et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat. Rev. Genet. 9(5), 356-369 (2008).
    • (2008) Nat. Rev. Genet. , vol.9 , Issue.5 , pp. 356-369
    • McCarthy, M.I.1    Abecasis, G.R.2    Cardon, L.R.3
  • 87
    • 79953057217 scopus 로고    scopus 로고
    • Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia
    • Vacic V, McCarthy S, Malhotra D et al. Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia. Nature 471(7339), 499-503 (2011).
    • (2011) Nature , vol.471 , Issue.7339 , pp. 499-503
    • Vacic, V.1    McCarthy, S.2    Malhotra, D.3
  • 88
    • 78049303903 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: A genome-wide analysis
    • Williams NM, Zaharieva I, Martin A et al. Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis. Lancet 376(9750), 1401-1408 (2010).
    • (2010) Lancet , vol.376 , Issue.9750 , pp. 1401-1408
    • Williams, N.M.1    Zaharieva, I.2    Martin, A.3
  • 89
    • 84873056939 scopus 로고    scopus 로고
    • Genome-wide association analysis of copy number variation in recurrent depressive disorder
    • Rucker JJ, Breen G, Pinto D et al. Genome-wide association analysis of copy number variation in recurrent depressive disorder. Mol. Psychiatry 18(2), 183-189 (2013).
    • (2013) Mol. Psychiatry , vol.18 , Issue.2 , pp. 183-189
    • Rucker, J.J.1    Breen, G.2    Pinto, D.3
  • 90
    • 84904960520 scopus 로고    scopus 로고
    • Copy number variants and therapeutic response to antidepressant medication in major depressive disorder
    • Tansey KE, Rucker JJ, Kavanagh DH et al. Copy number variants and therapeutic response to antidepressant medication in major depressive disorder. Pharmacogenomics J. 14(4), 395-399 (2014).
    • (2014) Pharmacogenomics J. , vol.14 , Issue.4 , pp. 395-399
    • Tansey, K.E.1    Rucker, J.J.2    Kavanagh, D.H.3
  • 91
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia C
    • International Schizophrenia C, Purcell SM, Wray NR et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460(7256), 748-752 (2009).
    • (2009) Nature , vol.460 , Issue.7256 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2
  • 92
    • 77956192737 scopus 로고    scopus 로고
    • Genomic imprinting and human disease
    • Hirasawa R, Feil R. Genomic imprinting and human disease. Essays Biochem. 48(1), 187-200 (2010).
    • (2010) Essays Biochem. , vol.48 , Issue.1 , pp. 187-200
    • Hirasawa, R.1    Feil, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.