Oxysophocarpine Ameliorates Carrageenan-induced Inflammatory Pain via Inhibiting Expressions of Prostaglandin E2 and Cytokines in Mice

Planta Medica

Volumn 81, Issue 10, 2015, Pages 791-797

  Yang, Yang ^a   Li, Yu Xiang ^a   Wang, Hong Ling ^a   Jin, Shao Ju ^b   Zhou, Ru ^a   Qiao, Hai Qi ^a   Du, Juan ^a   Wu, Jing ^a   Zhao, Cheng Jun ^a   Niu, Yang ^a   Sun, Tao ^a   Yu, Jian Qiang ^a,c  

^a NINGXIA MEDICAL UNIVERSITY   (China)

^b Luohe Medical College   (China)

^c Ningxia Engineering and Technology Research Center for Modernization of Hui Medicine   (China)

Author keywords

inflammation pain; Leguminosae; oxysophocarpine; pro inflammatory cytokines; prostaglandin E2; Sophora alopecuroides

Indexed keywords

ALKALOID; ANALGESIC AGENT; CARRAGEENAN; CYCLOOXYGENASE 2; CYTOKINE; EOSIN; HEMATOXYLIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYSOPHOCARPINE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; MAPK1 PROTEIN, MOUSE; NONSTEROID ANTIINFLAMMATORY AGENT; PTGS2 PROTEIN, MOUSE;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARRAGEENAN-INDUCED PAW EDEMA; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; INFLAMMATORY PAIN; MECHANICAL HYPERALGESIA; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DRUG EFFECTS; EDEMA; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; METABOLISM; PAIN;

FABACEAE; MUS; SOPHORA ALOPECUROIDES;

ALKALOIDS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; EDEMA; GENE EXPRESSION REGULATION; INFLAMMATION; INTERLEUKIN-1BETA; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PAIN;

EID: 84936985903     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0035-1546153     Document Type: Article

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