Omega-3 PUFA docosahexaenoic acid decreases LPS-stimulated MUC5AC production by altering EGFR-related signaling in NCI-H292 cells

Biochemical and Biophysical Research Communications

Volumn 463, Issue 4, 2015, Pages 1047-1052

  Binker, Marcelo G ^a   Binker Cosen, Makena J ^a   Richards, Daniel ^a   Binker Cosen, Andres A ^a   Freedman, Steven D ^b   Cosen Binker, Laura I ^a,b  

^a CBRHC Research Center   (Argentina)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Chronic obstructive pulmonary disease (COPD); Docosahexaenoic acid (DHA); Epidermal growth factor receptor (EGFR); Lipopolysaccharides (LPS); Mucin 5AC (MUC5AC); Polyunsaturated fatty acids (PUFA)

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; ACETYLCYSTEINE; DOCOSAHEXAENOIC ACID; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; ILOMASTAT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MUCIN 5AC; PYRROLIDINE DITHIOCARBAMATE; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; MUC5AC PROTEIN, HUMAN;

ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; DRUG EFFECTS; METABOLISM;

CELL LINE; DOCOSAHEXAENOIC ACIDS; HUMANS; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASE 9; MUCIN 5AC; NF-KAPPA B; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84936985098     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.06.056     Document Type: Article

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