LPS-stimulated MUC5AC production involves Rac1-dependent MMP-9 secretion and activation in NCI-H292 cells

Biochemical and Biophysical Research Communications

Volumn 386, Issue 1, 2009, Pages 124-129

  Binker, Marcelo G ^a   Binker Cosen, Andres A ^a   Richards, Daniel ^a   Oliver, Brenda ^a   Cosen Binker, Laura I ^a  

^a CBRHC Research Center   (Argentina)

Author keywords

Chronic obstructive pulmonary disease (COPD); Lipopolysaccharides (LPS); Matrix metalloproteinase 9 (MMP 9); MUC5AC, mucin 5AC; Mucin; NCI H292 cells; Rac1; Reactive oxygen species (ROS)

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; LIPOPOLYSACCHARIDE; MUCIN 5AC; PHOSPHATIDYLINOSITOL 3 KINASE; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

AIRWAY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL LINE, TUMOR; HUMANS; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASE 9; MUCIN 5AC; MUCUS; NADP; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RAC1 GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION;

EID: 67649170384     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.05.136     Document Type: Article

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