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Volumn 92, Issue 6, 2015, Pages

Enalapril normalizes endothelium-derived hyperpolarizing factor-mediated relaxation in mesenteric artery of adult hypertensive rats prenatally exposed to testosterone

Author keywords

Blood pressure; EDHF; Enalapril; Endothelium; Kcnn3 channel; Mesenteric arteries; Pregnancy; Testosterone

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; DIPEPTIDYL CARBOXYPEPTIDASE; ENALAPRIL; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; TESTOSTERONE; BIOLOGICAL FACTOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION FACTOR;

EID: 84936934962     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.115.130468     Document Type: Article
Times cited : (10)

References (52)
  • 1
    • 0034789020 scopus 로고    scopus 로고
    • Ion channels and their functional role in vascular endothelium
    • Nilius B, Droogmans G. Ion channels and their functional role in vascular endothelium. Physiol Rev 2001; 81:1415-1459.
    • (2001) Physiol Rev , vol.81 , pp. 1415-1459
    • Nilius, B.1    Droogmans, G.2
  • 2
    • 0344896757 scopus 로고    scopus 로고
    • + channels provide different facets of endothelium-dependent hyperpolarization in rat mesenteric artery
    • + channels provide different facets of endothelium-dependent hyperpolarization in rat mesenteric artery. J Physiol 2003; 553:183-189.
    • (2003) J Physiol , vol.553 , pp. 183-189
    • Crane, G.J.1    Gallagher, N.2    Dora, K.A.3    Garland, C.J.4
  • 5
    • 0037363729 scopus 로고    scopus 로고
    • +-channel inhibitors in rat isolated mesenteric arteries
    • +-channel inhibitors in rat isolated mesenteric arteries. Br J Pharmacol 2003; 138:1031-1035.
    • (2003) Br J Pharmacol , vol.138 , pp. 1031-1035
    • Hinton, J.M.1    Langton, P.D.2
  • 6
    • 81555204267 scopus 로고    scopus 로고
    • Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endotheliumderived hyperpolarizing factor in small arteries from rat
    • Stankevicius E, Dalsgaard T, Kroigaard C, Beck L, Boedtkjer E, Misfeldt MW, Nielsen G, Schjorring O, Hughes A, Simonsen U. Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endotheliumderived hyperpolarizing factor in small arteries from rat. J Pharmacol Exp Ther 2011; 339:842-850.
    • (2011) J Pharmacol Exp Ther , vol.339 , pp. 842-850
    • Stankevicius, E.1    Dalsgaard, T.2    Kroigaard, C.3    Beck, L.4    Boedtkjer, E.5    Misfeldt, M.W.6    Nielsen, G.7    Schjorring, O.8    Hughes, A.9    Simonsen, U.10
  • 7
    • 33748421398 scopus 로고    scopus 로고
    • Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture)
    • Feletou M, Vanhoutte PM. Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). Am J Physiol Heart Circ Physiol 2006; 291:H985-1002.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , pp. H985-H1002
    • Feletou, M.1    Vanhoutte, P.M.2
  • 12
    • 59449098672 scopus 로고    scopus 로고
    • Naphtho1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure
    • Sankaranarayanan A, Raman G, Busch C, Schultz T, Zimin PI, Hoyer J, Kohler R, Wulff H. Naphtho1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure. Mol Pharmacol 2009; 75:281-295.
    • (2009) Mol Pharmacol , vol.75 , pp. 281-295
    • Sankaranarayanan, A.1    Raman, G.2    Busch, C.3    Schultz, T.4    Zimin, P.I.5    Hoyer, J.6    Kohler, R.7    Wulff, H.8
  • 14
    • 77953112713 scopus 로고    scopus 로고
    • Low birth weight infants and the developmental programming of hypertension: a focus on vascular factors
    • Ligi I, Grandvuillemin I, Andres V, Dignat-George F, Simeoni U. Low birth weight infants and the developmental programming of hypertension: a focus on vascular factors. Semin Perinatol 2010; 34:188-192.
    • (2010) Semin Perinatol , vol.34 , pp. 188-192
    • Ligi, I.1    Grandvuillemin, I.2    Andres, V.3    Dignat-George, F.4    Simeoni, U.5
  • 15
    • 84859332979 scopus 로고    scopus 로고
    • Impaired vasodilation in the pathogenesis of hypertension: focus on nitric oxide, endothelialderived hyperpolarizing factors, and prostaglandins
    • Giles TD, Sander GE, Nossaman BD, Kadowitz PJ. Impaired vasodilation in the pathogenesis of hypertension: focus on nitric oxide, endothelialderived hyperpolarizing factors, and prostaglandins. J Clin Hypertens (Greenwich) 2012; 14:198-205.
    • (2012) J Clin Hypertens (Greenwich) , vol.14 , pp. 198-205
    • Giles, T.D.1    Sander, G.E.2    Nossaman, B.D.3    Kadowitz, P.J.4
  • 16
    • 84872160315 scopus 로고    scopus 로고
    • Pre-weaning growth hormone treatment reverses hypertension and endothelial dysfunction in adult male offspring of mothers undernourished during pregnancy
    • Gray C, Li M, Reynolds CM, Vickers MH. Pre-weaning growth hormone treatment reverses hypertension and endothelial dysfunction in adult male offspring of mothers undernourished during pregnancy. PLoS One 2013; 8:e53505.
    • (2013) PLoS One , vol.8
    • Gray, C.1    Li, M.2    Reynolds, C.M.3    Vickers, M.H.4
  • 17
    • 84899831306 scopus 로고    scopus 로고
    • Prenatal testosterone induces sex-specific dysfunction in endothelium-dependent relaxation pathways in adult male and female rats
    • Chinnathambi V, Yallampalli C, Sathishkumar K. Prenatal testosterone induces sex-specific dysfunction in endothelium-dependent relaxation pathways in adult male and female rats. Biol Reprod 2013; 89:1-9.
    • (2013) Biol Reprod , vol.89 , pp. 1-9
    • Chinnathambi, V.1    Yallampalli, C.2    Sathishkumar, K.3
  • 18
    • 77952816888 scopus 로고    scopus 로고
    • Impairment of endothelial SK(Ca) channels and of downstream hyperpolarizing pathways in mesenteric arteries from spontaneously hypertensive rats
    • Weston AH, Porter EL, Harno E, Edwards G. Impairment of endothelial SK(Ca) channels and of downstream hyperpolarizing pathways in mesenteric arteries from spontaneously hypertensive rats. Br J Pharmacol 2010; 160:836-843.
    • (2010) Br J Pharmacol , vol.160 , pp. 836-843
    • Weston, A.H.1    Porter, E.L.2    Harno, E.3    Edwards, G.4
  • 19
    • 4944267105 scopus 로고    scopus 로고
    • Changes in endothelium-derived hyperpolarizing factor in hypertension and ageing: response to chronic treatment with renin-angiotensin system inhibitors
    • Goto K, Fujii K, Kansui Y, Iida M. Changes in endothelium-derived hyperpolarizing factor in hypertension and ageing: response to chronic treatment with renin-angiotensin system inhibitors. Clin Exp Pharmacol Physiol 2004; 31:650-655.
    • (2004) Clin Exp Pharmacol Physiol , vol.31 , pp. 650-655
    • Goto, K.1    Fujii, K.2    Kansui, Y.3    Iida, M.4
  • 20
    • 33646496604 scopus 로고    scopus 로고
    • Endothelial dysfunction and impaired L-arginine transport in hypertension and genetically predisposed normotensive subjects
    • Yang Z, Kaye DM. Endothelial dysfunction and impaired L-arginine transport in hypertension and genetically predisposed normotensive subjects. Trends Cardiovasc Med 2006; 16:118-124.
    • (2006) Trends Cardiovasc Med , vol.16 , pp. 118-124
    • Yang, Z.1    Kaye, D.M.2
  • 21
    • 59649090735 scopus 로고    scopus 로고
    • Angiotensin II-induced hypertension is associated with a selective inhibition of endothelium-derived hyperpolarizing factormediated responses in the rat mesenteric artery
    • Dal-Ros S, Bronner C, Schott C, Kane MO, Chataigneau M, Schini-Kerth VB, Chataigneau T. Angiotensin II-induced hypertension is associated with a selective inhibition of endothelium-derived hyperpolarizing factormediated responses in the rat mesenteric artery. J Pharmacol Exp Ther 2009; 328:478-486.
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 478-486
    • Dal-Ros, S.1    Bronner, C.2    Schott, C.3    Kane, M.O.4    Chataigneau, M.5    Schini-Kerth, V.B.6    Chataigneau, T.7
  • 22
    • 34250860659 scopus 로고    scopus 로고
    • Reduced expression of SKCa and IKCa channel proteins in rat small mesenteric arteries during angiotensin II-induced hypertension
    • Hilgers RH, Webb RC. Reduced expression of SKCa and IKCa channel proteins in rat small mesenteric arteries during angiotensin II-induced hypertension. Am J Physiol Heart Circ Physiol 2007; 292:H2275-H2284.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , pp. H2275-H2284
    • Hilgers, R.H.1    Webb, R.C.2
  • 23
  • 24
    • 0030482532 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition restores flow-dependent and cold pressor test-induced dilations in coronary arteries of hypertensive patients
    • Antony I, Lerebours G, Nitenberg A. Angiotensin-converting enzyme inhibition restores flow-dependent and cold pressor test-induced dilations in coronary arteries of hypertensive patients. Circulation 1996; 94: 3115-3122.
    • (1996) Circulation , vol.94 , pp. 3115-3122
    • Antony, I.1    Lerebours, G.2    Nitenberg, A.3
  • 25
    • 0042594673 scopus 로고    scopus 로고
    • Perindopril augments ecto-ATP diphosphohydrolase activity and enhances endothelial anti-platelet function in human umbilical vein endothelial cells
    • Kishi Y, Ohta S, Kasuya N, Sakita SY, Ashikaga T, Isobe M. Perindopril augments ecto-ATP diphosphohydrolase activity and enhances endothelial anti-platelet function in human umbilical vein endothelial cells. J Hypertens 2003; 21:1347-1353.
    • (2003) J Hypertens , vol.21 , pp. 1347-1353
    • Kishi, Y.1    Ohta, S.2    Kasuya, N.3    Sakita, S.Y.4    Ashikaga, T.5    Isobe, M.6
  • 26
    • 0029028797 scopus 로고
    • Vascular protective effects of ACE inhibitors and calcium antagonists: theoretical basis for a combination therapy in hypertension and other cardiovascular diseases
    • Luscher TF, Wenzel RR, Moreau P, Takase H. Vascular protective effects of ACE inhibitors and calcium antagonists: theoretical basis for a combination therapy in hypertension and other cardiovascular diseases. Cardiovasc Drugs Ther 1995; 9(suppl 3):509-523.
    • (1995) Cardiovasc Drugs Ther , vol.9 , pp. 509-523
    • Luscher, T.F.1    Wenzel, R.R.2    Moreau, P.3    Takase, H.4
  • 27
    • 85047694275 scopus 로고    scopus 로고
    • Vascular protection of ACE inhibitors
    • Messerli FH. Vascular protection of ACE inhibitors. Arch Intern Med 2003; 163:2791-2792.
    • (2003) Arch Intern Med , vol.163 , pp. 2791-2792
    • Messerli, F.H.1
  • 28
    • 77149139148 scopus 로고    scopus 로고
    • Protection of retinal vasculature by losartan against apoptosis and vasculopathy in rats with spontaneous hypertension
    • Yang D, Zhang M, Huang X, Fang F, Chen B, Wang S, Cai J, Shi X, Qu J, Geng YJ. Protection of retinal vasculature by losartan against apoptosis and vasculopathy in rats with spontaneous hypertension. J Hypertens 2010; 28:510-519.
    • (2010) J Hypertens , vol.28 , pp. 510-519
    • Yang, D.1    Zhang, M.2    Huang, X.3    Fang, F.4    Chen, B.5    Wang, S.6    Cai, J.7    Shi, X.8    Qu, J.9    Geng, Y.J.10
  • 31
    • 84906256475 scopus 로고    scopus 로고
    • Gestational exposure to elevated testosterone levels induces hypertension via heightened vascular angiotensin II type 1 receptor signaling in rats
    • Chinnathambi V, More AS, Hankins GD, Yallampalli C, Sathishkumar K. Gestational exposure to elevated testosterone levels induces hypertension via heightened vascular angiotensin II type 1 receptor signaling in rats. Biol Reprod 2014; 91:6.
    • (2014) Biol Reprod , vol.91 , pp. 6
    • Chinnathambi, V.1    More, A.S.2    Hankins, G.D.3    Yallampalli, C.4    Sathishkumar, K.5
  • 32
    • 84904503892 scopus 로고    scopus 로고
    • Elevated testosterone levels during rat pregnancy cause hypersensitivity to angiotensin II and attenuation of endothelium-dependent vasodilation in uterine arteries
    • Chinnathambi V, Selvanesan BC, Vincent KL, Saade GR, Hankins GD, Yallampalli C, Sathishkumar K. Elevated testosterone levels during rat pregnancy cause hypersensitivity to angiotensin II and attenuation of endothelium-dependent vasodilation in uterine arteries. Hypertension 2014; 64:405-414.
    • (2014) Hypertension , vol.64 , pp. 405-414
    • Chinnathambi, V.1    Selvanesan, B.C.2    Vincent, K.L.3    Saade, G.R.4    Hankins, G.D.5    Yallampalli, C.6    Sathishkumar, K.7
  • 33
    • 79961012666 scopus 로고    scopus 로고
    • Prenatal testosterone-induced fetal growth restriction is associated with down-regulation of rat placental amino acid transport
    • Sathishkumar K, Elkins R, Chinnathambi V, Gao H, Hankins GD, Yallampalli C. Prenatal testosterone-induced fetal growth restriction is associated with down-regulation of rat placental amino acid transport. Reprod Biol Endocrinol 2011; 9:1-12.
    • (2011) Reprod Biol Endocrinol , vol.9 , pp. 1-12
    • Sathishkumar, K.1    Elkins, R.2    Chinnathambi, V.3    Gao, H.4    Hankins, G.D.5    Yallampalli, C.6
  • 35
    • 84861578588 scopus 로고    scopus 로고
    • Protein restriction during pregnancy induces hypertension in adult female rat offspring-influence of oestradiol
    • Sathishkumar K, Elkins R, Yallampalli U, Yallampalli C. Protein restriction during pregnancy induces hypertension in adult female rat offspring-influence of oestradiol. Br J Nutr 2011; 1-9.
    • (2011) Br J Nutr , pp. 1-9
    • Sathishkumar, K.1    Elkins, R.2    Yallampalli, U.3    Yallampalli, C.4
  • 36
  • 37
    • 65349151303 scopus 로고    scopus 로고
    • Calcium-activated potassium channels and endothelial dysfunction: therapeutic options?
    • Feletou M. Calcium-activated potassium channels and endothelial dysfunction: therapeutic options? Br J Pharmacol 2009; 156:545-562.
    • (2009) Br J Pharmacol , vol.156 , pp. 545-562
    • Feletou, M.1
  • 38
    • 70349895458 scopus 로고    scopus 로고
    • + channels in normal and impaired EDHF-dilator responses-relevance to cardiovascular pathologies and drug discovery
    • + channels in normal and impaired EDHF-dilator responses-relevance to cardiovascular pathologies and drug discovery. Br J Pharmacol 2009; 157: 509-526.
    • (2009) Br J Pharmacol , vol.157 , pp. 509-526
    • Grgic, I.1    Kaistha, B.P.2    Hoyer, J.3    Kohler, R.4
  • 40
    • 78149243708 scopus 로고    scopus 로고
    • Obesity up-regulates intermediate conductance calciumactivated potassium channels and myoendothelial gap junctions to maintain endothelial vasodilator function
    • Chadha PS, Haddock RE, Howitt L, Morris MJ, Murphy TV, Grayson TH, Sandow SL. Obesity up-regulates intermediate conductance calciumactivated potassium channels and myoendothelial gap junctions to maintain endothelial vasodilator function. J Pharmacol Exp Ther 2010; 335:284-293.
    • (2010) J Pharmacol Exp Ther , vol.335 , pp. 284-293
    • Chadha, P.S.1    Haddock, R.E.2    Howitt, L.3    Morris, M.J.4    Murphy, T.V.5    Grayson, T.H.6    Sandow, S.L.7
  • 41
    • 84863996281 scopus 로고    scopus 로고
    • Prenatal testosterone exposure leads to hypertension that is gonadal hormone-dependent in adult rat male and female offspring
    • Chinnathambi V, Balakrishnan M, Yallampalli C, Sathishkumar K. Prenatal testosterone exposure leads to hypertension that is gonadal hormone-dependent in adult rat male and female offspring. Biol Reprod 2012; 206(507):e1-507.e10.
    • (2012) Biol Reprod , vol.206 , Issue.507 , pp. e1-e507+e10
    • Chinnathambi, V.1    Balakrishnan, M.2    Yallampalli, C.3    Sathishkumar, K.4
  • 43
    • 11144285411 scopus 로고    scopus 로고
    • Maternal low-protein diet in rat pregnancy programs blood pressure through sex-specific mechanisms
    • McMullen S, Langley-Evans SC. Maternal low-protein diet in rat pregnancy programs blood pressure through sex-specific mechanisms. Am J Physiol Regul Integr Comp Physiol 2005; 288:R85-R90.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288 , pp. R85-R90
    • McMullen, S.1    Langley-Evans, S.C.2
  • 44
    • 0037340172 scopus 로고    scopus 로고
    • Placental insufficiency leads to development of hypertension in growth-restricted offspring
    • Alexander BT. Placental insufficiency leads to development of hypertension in growth-restricted offspring. Hypertension 2003; 41:457-462.
    • (2003) Hypertension , vol.41 , pp. 457-462
    • Alexander, B.T.1
  • 46
    • 0141893558 scopus 로고    scopus 로고
    • Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery
    • Bussemaker E, Popp R, Fisslthaler B, Larson CM, Fleming I, Busse R, Brandes RP. Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery. Hypertension 2003; 42: 562-568.
    • (2003) Hypertension , vol.42 , pp. 562-568
    • Bussemaker, E.1    Popp, R.2    Fisslthaler, B.3    Larson, C.M.4    Fleming, I.5    Busse, R.6    Brandes, R.P.7
  • 47
    • 21844438514 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors reveal non-NO-, non-prostacycline-mediated endothelium-dependent relaxation in internal thoracic artery of hypertensive patients
    • Deja MA, Golba KS, Widenka K, Mrozek R, Biernat J, Kolowca M, Malinowski M, Wos S. Angiotensin-converting enzyme inhibitors reveal non-NO-, non-prostacycline-mediated endothelium-dependent relaxation in internal thoracic artery of hypertensive patients. Int J Cardiol 2005; 102: 455-460.
    • (2005) Int J Cardiol , vol.102 , pp. 455-460
    • Deja, M.A.1    Golba, K.S.2    Widenka, K.3    Mrozek, R.4    Biernat, J.5    Kolowca, M.6    Malinowski, M.7    Wos, S.8
  • 48
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone
    • Rajagopalan S, Kurz S, Munzel T, Tarpey M, Freeman BA, Griendling KK, Harrison DG. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J Clin Invest 1996; 97:1916-1923.
    • (1996) J Clin Invest , vol.97 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Munzel, T.3    Tarpey, M.4    Freeman, B.A.5    Griendling, K.K.6    Harrison, D.G.7
  • 50
    • 84890670674 scopus 로고    scopus 로고
    • Oxidative stress impairs IKCaand SKCa-mediated vasodilatation in mesenteric arteries from diabetic rats
    • Zhao L, Wang Y, Ma X, Wang Y, Deng X. Oxidative stress impairs IKCaand SKCa-mediated vasodilatation in mesenteric arteries from diabetic rats. Nan Fang Yi Ke Da Xue Xue Bao 2013; 33:939-944.
    • (2013) Nan Fang Yi Ke Da Xue Xue Bao , vol.33 , pp. 939-944
    • Zhao, L.1    Wang, Y.2    Ma, X.3    Wang, Y.4    Deng, X.5
  • 51
    • 84893864668 scopus 로고    scopus 로고
    • Advanced glycation end products impair K(Ca)3.1-and K(Ca)2.3-mediated vasodilatation via oxidative stress in rat mesenteric arteries
    • Zhao LM, Wang Y, Ma XZ, Wang NP, Deng XL. Advanced glycation end products impair K(Ca)3.1-and K(Ca)2.3-mediated vasodilatation via oxidative stress in rat mesenteric arteries. Pflugers Arch 2014; 466: 307-317.
    • (2014) Pflugers Arch , vol.466 , pp. 307-317
    • Zhao, L.M.1    Wang, Y.2    Ma, X.Z.3    Wang, N.P.4    Deng, X.L.5
  • 52
    • 0029869932 scopus 로고    scopus 로고
    • Endothelium-dependent relaxation in resistance arteries from spontaneously hypertensive rats: effect of longterm treatment with perindopril, quinapril, hydralazine or amlodipine
    • Bennett MA, Hillier C, Thurston H. Endothelium-dependent relaxation in resistance arteries from spontaneously hypertensive rats: effect of longterm treatment with perindopril, quinapril, hydralazine or amlodipine. J Hypertens 1996; 14:389-397.
    • (1996) J Hypertens , vol.14 , pp. 389-397
    • Bennett, M.A.1    Hillier, C.2    Thurston, H.3


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