Selective blockade of endothelial Ca 2+-activated small- and intermediate-conductance K +-channels suppresses EDHF-mediated vasodilation

British Journal of Pharmacology

Volumn 138, Issue 4, 2003, Pages 594-601

  Eichler, Ines ^a   Wibawa, Judith ^a   Grgic, Ivica ^a   Knorr, Andrea ^a   Brakemeier, Susanne ^a   Pries, Axel R ^b   Hoyer, Joachim ^a   Köhler, Ralf ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Ca 2+ activated K + channels; Clotrimazole; EDHF; Endothelium; TRAM 34

Indexed keywords

1 [(2 CHLOROPHENYL)DIPHENYL] 1H PYRAZOLE; 2 (2 CHLOROPHENYL) 2,2 DIPHENYLACETONITRILE; ACETYLCHOLINE; APAMIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; CHARYBDOTOXIN; CLOTRIMAZOLE; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; NITRIC OXIDE; PHENYLEPHRINE; POTASSIUM CHANNEL BLOCKING AGENT; PROSTACYCLIN; TRAM 34; TRAM 39; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; CAROTID ARTERY; CONTROLLED STUDY; CORONARY ARTERY DILATATION; ENDOTHELIUM CELL; HYPERPOLARIZATION; INHIBITION KINETICS; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VOLTAGE CLAMP;

ANIMALS; BIOLOGICAL FACTORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; MALE; MEMBRANE POTENTIALS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; RATS, SPRAGUE-DAWLEY; VASODILATION;

EID: 0037295387     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705075     Document Type: Article

References (34)

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