Prenatal testosterone induces sex-specific dysfunction in endothelium-dependent relaxation pathways in adult male and female rats

Biology of Reproduction

Volumn 89, Issue 4, 2013, Pages

  Chinnathambi, Vijayakumar ^a   Yallampalli, Chandrasekhar ^a   Sathishkumar, Kunju ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Blood pressure; EDHF; Endothelium; Kcnn3 channels; NO; NOS3; Prenatal testosterone; Sex specific; Vascular function

Indexed keywords

ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; LEMAKALIM; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNN3; POTASSIUM CHANNEL KCNN4; TESTOSTERONE; UNCLASSIFIED DRUG;

ADULT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; ENDOTHELIUM; FEMALE; MALE; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEXUAL DYSFUNCTION; VASODILATATION;

BLOOD PRESSURE; EDHF; ENDOTHELIUM; KCNN3 CHANNELS; NO; NOS3; PRENATAL TESTOSTERONE; SEX-SPECIFIC; VASCULAR FUNCTION;

ANDROGENS; ANIMALS; BIOLOGICAL FACTORS; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; FEMALE; FETAL DEVELOPMENT; HYPERTENSION; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; MESENTERIC ARTERIES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; TESTOSTERONE; TESTOSTERONE PROPIONATE; VASODILATION;

EID: 84899831306     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.111542     Document Type: Article

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