The antinociceptive effects of the tetracyclic triterpene euphol in inflammatory and neuropathic pain models: The potential role of PKCε

Neuroscience

Volumn 303, Issue , 2015, Pages 126-137

  Dutra, R C ^a,d   Bicca, M A ^a   Segat, G C ^a   Silva, K A B S ^a   Motta, E M ^a   Pianowski, L F ^b   Costa, R ^a,c   Calixto, J B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b Kyolab Ltda   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d Departmento de Biotecnologia Farmaceutica Universidade Federal do Rio de Janeiro ^*  (Brazil)

Author keywords

Euphol; Inflammation; Persistent pain; PKC

Indexed keywords

CANNABINOID; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; EUPHOL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOENZYME; PACLITAXEL; PROSTAGLANDIN E2; PROTEIN KINASE C EPSILON; PROTEIN KINASE C INHIBITOR; TRITERPENOID; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; AUTACOID; LANOSTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTIVE EFFECT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME INDUCTION; INFLAMMATORY PAIN; MALE; MECHANICS; MELANOMA CELL; MOUSE; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RAT; RODENT; SINGLE DRUG DOSE; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PAIN; PAIN THRESHOLD; SIGNAL TRANSDUCTION; WISTAR RAT;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; DINOPROSTONE; INFLAMMATION MEDIATORS; LANOSTEROL; MALE; MICE; PAIN; PAIN THRESHOLD; PROTEIN KINASE C-EPSILON; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 84936885462     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.06.051     Document Type: Article

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