Puerarin suppresses angiotensin II-induced cardiac hypertrophy by inhibiting NADPH oxidase activation and oxidative stress-triggered AP-1 signaling pathways

Journal of Pharmacy and Pharmaceutical Sciences

Volumn 18, Issue 2, 2015, Pages 235-248

  Chen, Gang ^a   Cao, Qiang ^b   Cui, Xiangli ^a   Pan, Shifen ^a   Shen, Chong ^c   Liu, Lihong ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b GANSU UNIVERSITY OF CHINESE MEDICINE   (China)

^c INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; MITOGEN ACTIVATED PROTEIN KINASE 1; PUERARIN; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; ISOFLAVONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CARDIOVASCULAR RESPONSE; CELL VIABILITY; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; ENZYME ACTIVITY; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; MALE; MOUSE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SYSTOLIC BLOOD PRESSURE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CARDIOMEGALY; DOSE RESPONSE; DRUG EFFECTS; ENZYME ACTIVATION; METABOLISM; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANGIOTENSIN II; ANIMALS; CARDIOMEGALY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ISOFLAVONES; MICE; MICE, INBRED C57BL; NADPH OXIDASE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTOR AP-1;

EID: 84936856674     PISSN: None     EISSN: 14821826     Source Type: Journal    
DOI: 10.18433/j3n318     Document Type: Article

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