Puerarin inhibits the retinal pericyte apoptosis induced by advanced glycation end products in vitro and in vivo by inhibiting NADPH oxidase-related oxidative stress

Free Radical Biology and Medicine

Volumn 53, Issue 2, 2012, Pages 357-365

  Kim, Junghyun ^a   Kim, Ki Mo ^a   Kim, Chan Sik ^a   Sohn, Eunjin ^a   Lee, Yun Mi ^a   Jo, Kyuhyung ^a   Kim, Jin Sook ^a  

^a Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

Advanced glycation end products; Apoptosis; Iso flavones; NADPH oxidase; Oxidative stress; Puerarin; Retinal pericyte

Indexed keywords

ADVANCED GLYCATION END PRODUCT; BOVINE SERUM ALBUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P47; PUERARIN; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DENSITY; CELL LOSS; CONTROLLED STUDY; DNA BINDING; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROVASCULARIZATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PERICYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RETINA BLOOD VESSEL; RETINA CELL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; CATTLE; CELLS, CULTURED; GENE EXPRESSION REGULATION; GLYCOSYLATION END PRODUCTS, ADVANCED; INTRAVITREAL INJECTIONS; ISOFLAVONES; NADPH OXIDASE; NF-KAPPA B; OXIDATIVE STRESS; PERICYTES; PHOSPHORYLATION; RAC1 GTP-BINDING PROTEIN; RATS; REACTIVE OXYGEN SPECIES; RETINA; SERUM ALBUMIN, BOVINE; SIGNAL TRANSDUCTION;

BOVINAE; RATTUS;

EID: 84862282700     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.04.030     Document Type: Article

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