Clonal expansion of hepatocytes with a selective advantage occurs during all stages of chronic hepatitis B virus infection

Journal of Viral Hepatitis

Volumn 22, Issue 9, 2015, Pages 737-753

  Tu, T ^a,b,c   Mason, W S ^d   Clouston, A D ^e   Shackel, N A ^b,c,f   McCaughan, G W ^b,c,f   Yeh, M M ^g   Schiff, E R ^h   Ruszkiewicz, A R ⁱ   Chen, J W ^j   Harley, H A J ^k   Stroeher, U H ^a   Jilbert, A R ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b CENTENARY INSTITUTE   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d FOX CHASE CANCER CENTER   (United States)

^e UNIVERSITY OF QUEENSLAND   (Australia)

^f ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^g UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

ⁱ CENTRE FOR CANCER BIOLOGY   (Australia)

^j FLINDERS MEDICAL CENTRE   (Australia)

^k ROYAL ADELAIDE HOSPITAL   (Australia)

more..

Author keywords

clonal expansion of hepatocytes; hepatitis B virus; hepatocellular carcinoma; inverse nested PCR; laser microdissection; virus cell DNA junction

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; HEPATITIS E ANTIGEN; VIRUS DNA;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER INCIDENCE; CELL DEATH; CELL DIVISION; CELL EXPANSION; CELL JUNCTION; CELL SURVIVAL; CHRONIC HEPATITIS B; CLINICAL ARTICLE; CLONAL CELL LINE; COMPUTER SIMULATION; CONTROLLED STUDY; DISEASE COURSE; DNA EXTRACTION; DNA INTEGRATION; DNA SEQUENCE; FEMALE; GENE AMPLIFICATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LASER MICRODISSECTION; LIVER CELL; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; SEROCONVERSION; TISSUE FIXATION; VERY ELDERLY; VIRUS CELL INTERACTION; AGE; CELL PROLIFERATION; CLONAL EVOLUTION; GENETICS; HEPATITIS B; HEPATITIS B VIRUS; LASER CAPTURE MICRODISSECTION; LIVER; LIVER TUMOR; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; TIME; VIRUS DNA CELL DNA INTERACTION; YOUNG ADULT;

ADULT; AGE FACTORS; AGED; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CLONAL EVOLUTION; DNA, VIRAL; FEMALE; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HEPATOCYTES; HUMANS; LASER CAPTURE MICRODISSECTION; LIVER; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; TIME FACTORS; VIRUS INTEGRATION; YOUNG ADULT;

EID: 84936846131     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12380     Document Type: Article

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