Increase in the frequency of hepadnavirus DNA integrations by oxidative DNA damage and inhibition of DNA repair

Journal of Virology

Volumn 71, Issue 7, 1997, Pages 5455-5463

  Petersen, Joerg ^a   Dandri, Maura ^a   Bürkle, Alexander ^b   Zhang, Lunli ^a   Rogler, Charles E ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OXYGEN RADICAL; VIRUS DNA;

ANIMAL CELL; ARTICLE; DNA DAMAGE; DNA INTEGRATION; DNA REPAIR; DNA STRAND BREAKAGE; DNA VIRUS; HEPATITIS B VIRUS; LIVER CARCINOGENESIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; VIRUS GENOME;

EID: 0031007369     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.7.5455-5463.1997     Document Type: Article

References (56)

1. Brechot, C., M. Hadchouel, J. Scotto, M. Fonck, F. Potet, G. N. Vyas, and P. Tiollais. 1981. State of hepatitis B virus DNA in hepatocytes of patients with hepatitis B surface antigen-positive and -negative liver disease. Proc. Natl. Acad. Sci. USA 78:3906-3910.
2. Buendia, M. A. 1992. Hepatitis B viruses and hepatocellular carcinoma. Adv. Cancer Res. 59:167-226.
3. Bürkle, A., K. Grube, and J. H. Küpper. 1992. Poly(ADP-ribosyl)ation: its role in inducible DNA amplification, and its correlation with the longevity of mammalian species. Exp. Clin. Immunogenet. 9:230-240.
4. Bürkle, A., R. Heilbronn, and H. zur Hausen. 1990. Potentiation of carcinogen-induced methotrexate resistance and dihydrofolate reductase gene amplification by inhibitors of poly(adenosine diphosphate-ribose) polymerase. Cancer Res. 50:5756-5760.
5. Bürkle, A., T. Meyer, H. Hilz, and H. zur Hausen. 1987. Enhancement of N-methyl,N′-nitro-N-nitrosoguanidine-induced DNA amplification in a simian virus 40-transformed Chinese hamster cell line by 3-aminobenzamide. Cancer Res. 47:3632-3636.
6. Chang, M. H., H. C. Hsu, C. Y. Lee, D. S. Chen, C. H. Lee, and K. S. Lin. 1984. Fraternal hepatocellular carcinoma in young children in two families. Cancer 53:1807-1810.
7. Condreay, L., C. Aldrich, L. Coates, W. Mason, and T. T. Wu. 1990. Efficient duck hepatitis B virus production by an avian tumor cell line. J. Virol. 64:3249-3258.
8. De The, H., A. Marchio, P. Tiollais, and A. Dejean. 1987. A novel thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma. Nature 330:667-670.
9. Durkacz, B., O. Omidiji, D. A. Gray, and S. Shall. 1980. (ADPR) participates in DNA excision repair. Nature 283:593-596.
10. Feitelson, M. 1992. Hepatitis B virus infection and hepatocellular carcinoma. Clin. Microbiol. Rev. 5:275-301.
11. Fourel, G., C. Trepo, L. Bougueleret, B. Henglein, A. Ponzetto, P. Tiollais, and M. A. Buendia. 1990. Frequent activation of N-myc genes by hepadnaviral insertion in woodchuck liver tumors. Nature 347:294-298.
12. Fourel, G., J. Conturier, Y. Wei, F. Apiou, P. Tiollais, and M. A. Buendia. 1994. Evidence for long-range oncogene activation by hepadnavirus insertion. EMBO J. 13:2526-2534.
13. Gaken, J. A., M. Tavassoli, S. U. Gan, S. Vallian, I. Giddings, D. C. Darling, J. Galea-Lauri, M. G. Thomas, H. Abedi, V. Schreiber, J. M. deMurcia, M. K. Collins, S. Shall, and F. Farzaneh. 1996. Efficient retroviral infection of mammalian cells is blocked by inhibition of poly(ADP-ribose) polymerase activity. J. Virol. 70:3992-4000.
14. Ganem, D., and H. E. Varmus. 1987. The molecular biology of the hepatitis B viruses. Annu. Rev. Biochem. 56:651-693.
15. Gong, S. S., A. D. Jensen, and C. E. Rogler. 1996. Loss and acquisition of duck hepatitis B virus integrations in lineages of LMH-D2 chicken hepatoma cells. J. Virol. 70:2000-2007.
16. Gong, S. S., A. D. Jensen, H. Wang, and C. E. Rogler. 1995. Duck hepatitis B virus integrations in LMH chicken hepatoma cells: identification and characterization of new episomally derived integrations. J. Virol. 69:8102-8108.
17. Gracef, E., W. H. Caselmann, J. Wells, and R. Koshy. 1994. Insertional activation of mevalonate kinase by hepatitis B virus DNA in a human hepatoma cell line. Oncogene 3:537-540.
18. Hagen, T. M., S. Huang, J. Curnutte, P. Fowler, V. Martinez, C. M. Wehr, B. N. Ames, and F. V. Chisari. 1994. Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma. Proc. Natl. Acad. Sci. USA 91:12808-12812.
19. Hansen, L. J., B. C. Tennant, C. Seeger, and D. Ganem. 1993. Differential activation of myc gene family members in hepatic carcinogenesis by closely related hepatitis B viruses. Mol. Cell. Biol. 13:659-667.
20. Hino, O., T. B. Shows, and C. E. Rogler. 1986. Hepatitis B virus integration site in hepatocellular carcinoma at chromosome 17:18 translocation. Proc. Natl. Acad. Sci. USA 83:8338-8342.
21. Hsu, H. C., M. Z. Wu, M. H. Chang, I. J. Su, and D. S. Chen. 1987. Childhood hepatocellular carcinoma develops exclusively in hepatitis B surface antigen carriers in three decades in Taiwan. Report of 51 cases strongly associated with rapid development of liver cirrhosis. J. Hepatol. 5:260-267.
22. Huang, S. N., and F. V. Chisari. 1995. Strong, sustained hepatocellular proliferation precedes hepatocarcinogenesis in hepatitis B surface antigen transgenic mice. Hepatology 21:620-626.
23. Kasi, H., and S. Nishimura. 1984. Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents. Nucleic Acids Res 12:2137-2145.
24. Kawaguchi, T., K. Nomura, Y. Hirayama, and T. Kitagawa. 1987. Establish ment and characterization of a chicken hepatocellular carcinoma cell line, LMH. Cancer Res. 47:4460-4464.
25. Kew, M. C., J. Hodkinson, A. C. Paterson, and E. Song. 1982. Hepatitis B virus infection in black children with hepatocellular carcinoma. J. Med. Virol. 9:201-207.
26. Küpper, J.-H., M. Müller, M. K. Jacobson, J. Tatsumi-Miyajima, D. L. Coyle, E. L. Jacobson, and A. Bürkle. 1995. trans-dominant inhibition of poly(ADP-ribosyl)ation sensitizes cells against γ-irradiation and N-methyl-N′-nitro-N-nitrosoguanidine but does not limit DNA replication of a polyomavirus replicon. Mol. Cell. Biol. 15:3154-3163.
27. Küpper, J. H., L. van Gool, and A. Bürkle. 1995. Molecular genetic systems to study the role of poly(ADP-ribosyl)ation in the cellular response to DNA damage. Biochimie 77:450-455.
28. Lindahl-Kiessling, K., and S. Shall. 1987. Nicotinamide deficiency and benzamide-induced sister chromatid exchanges. Carcinogenesis 8:1185-1188.
29. Mandart, E., A. Kay, and F. Galibert. 1984. Nucleotide sequence of a cloned duck hepatitis B virus genome: comparison with woodchuck and human hepatitis B virus sequences. J. Virol. 49:782-792.
30. Mels, G. C., G. Bellati, G. Leandro, M. R. Brunetto, O. Vicari, M. Borzio, P. Piantino, G. Fornaciari, G. Scudeller, G. Angeli, et al. 1994. Fluctuations in viremia, aminotransferases and IgM antibody to hepatitis B core antigen in chronic hepatitis B patients with disease exacerbations. Liver 14:175-181.
31. Molinete, M., W. Vermeulen, A. Burkle, J. Menissier-de Murcia, J. H. Kupper, J. H. Hoeijmakers, and G. de Murcia. 1993. Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells. EMBO J. 12:2109-2117.
32. Ohashi, Y., K. Ueda, M. Kawaichi, and O. Hayaishi. 1983. Activation of DNA ligase by poly(ADP-ribose) in chromatin. Proc. Natl. Acad. Sci. USA 80:3604-3607.
33. Popper, H., D. A. Shafritz, and J. H. Hoofnagle. 1987. Relation of the hepatitis B virus carrier state to hepatocellular carcinoma. Hepatology 7:764-772.
34. Rogler, C. E. 1991. Cellular and molecular mechanisms of hepatocarcinogenesis associated with hepadnavirus infection. Curr. Top. Microbiol. Immunol. 168:103-141.
35. Rogler, C. E., and J. Summers. 1984. Cloning and structural analysis of integrated woodchuck hepatitis virus sequences from a chronically infected liver. J. Virol. 50:832-837.
36. Rogler, C. E., M. Sherman, C. Y. Su, and D. A. Shafritz. 1985. Deletion in chromosome 11p associated with a hepatitis B integration site in hepatocelluar carcinoma. Science 230:319-322.
37. - release by activated Kupffer cells upon hypoxia-reoxygenation. Am. J. Physiol. 261:G601-G607.
38. Satoh, M. S., and T. Lindahl. 1992. Role of poly(ADP-ribose) formation in DNA repair. Nature 356:356-358.
39. Satoh, M. S., G. G. Poivier, and T. Lindahl. 1993. NAD (+)-dependent repair of damaged DNA by human cell extracts. J. Biol. Chem. 268:5480-5487.
40. Schraufstatter, I. U., P. A. Hyslop, D. B. Hinshaw, R. G. Spragg, L. A. Sklar, and C. G. Cochrane. 1986. Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase. Proc. Natl. Acad. Sci. USA 83:4908-4912.
41. Schraufstatter, I. U., D. B. Hinshaw, P. A. Hyslop, R. G. Spragg, and C. G. Cochrane. 1986. Oxidant injury of cells. J. Clin. Invest. 77:1312-1320.
42. Shafritz, D. A. 1982. Integration of HBV-DNA into liver and hepatocellular carcinoma cells during persistent HBV infection. J. Cell. Biochem. 20:303-316.
43. Shafritz, D. A., D. Shouval, H. I. Sherman, S. J. Hadziyannis, and M. C. Kew. 1981. Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous liver biopsies and post-mortem tissue specimens. N. Engl. J. Med. 305:1067-1073.
44. Shall, S. 1995. ADP-ribosylation reactions. Biochimie 77:313-318.
45. Shall, S. 1994. The function of poly(ADP-ribosylation) in DNA breakage and rejoining. Mol. Cell. Biochem. 138:71-75.
46. Shibutani, S., M. Takeshita, and A. P. Grollmann. 1991. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature 349:431-434.
47. Shih, C., K. Burke, M. J. Chou, J. B. Zeldis, C. S. Yang, C. S. Lee, K. J. Isselbacher, J. R. Wands, and H. Goodmann. 1987. Tight clustering of human hepatitis B virus integration sites in hepatomas near a triple-stranded region. J. Virol. 61:3491-3498.
48. Shimoda, R., M. Nagashima, M. Sakamoto, N. Yamaguchi, S. Hirohashi, J. Yokota, and H. Kasai. 1994. Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis. Cancer Res. 54:3171-3172.
49. Single, B. L., Y. Zhou, and J. Butel. 1991. Hepatitis B virus integration in human chromosome 17p near the p53 gene identifies the region of the chromosome commonly deleted in virus-positive hepatocellular carcinomas. Cancer Res. 51:49-54.
50. Southern, E. M. 1975. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:503-517.
51. Waldmann, A. S., and B. C. Waldmann. 1991. Stimulation of intrachromosomal homologous recombination in mammalian cells by an inhibitor of poly(ADP-ribosylation). Nucleic Acids Res. 19:5943-5947.
52. Wang, J., F. Zindy, X. Chenivesse, E. Lamas, B. Henglein, and C. Brechot. 1992. Modification of cyclin A expression by hepatitis B virus DNA integration in a hepatocellular carcinoma. Oncogcne 7:1653-1656.
53. Wei, Y., G. Fourel, A. Ponzetto, M. Silvestro, P. Tiollais, and M.-A. Buendia. 1992. Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors. J. Virol. 66:5265-5276.
54. Wood, M. L., M. Dizdaroglu, E. Gajewski, and J. M. Essigmann. 1990. Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome. Biochemistry 29:7024-7032.
55. Wroblewski, F. 1959. The clinical significance of transaminase activities of serum. Am. J. Med. 27:911-913.
56. Yaginuma, K., H. Kobayashi, M. Kobayashi, T. Morishima, K. Matsuyama, and K. Koike. 1987. Multiple integration sites of hepatitis B virus DNA in hepatocellular carcinoma and chronic active hepatitis tissue from children. J. Virol. 61:1808-1813.