Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma

Nature Communications

Volumn 6, Issue , 2015, Pages

  Seki, Masafumi ^a   Nishimura, Riki ^a   Yoshida, Kenichi ^a,b   Shimamura, Teppei ^c,d   Shiraishi, Yuichi ^c   Sato, Yusuke ^a,b   Kato, Motohiro ^a,c,e   Chiba, Kenichi ^c   Tanaka, Hiroko ^c   Hoshino, Noriko ^a   Nagae, Genta ^f   Shiozawa, Yusuke ^a,b   Okuno, Yusuke ^a,d   Hosoi, Hajime ^g   Tanaka, Yukichi ^h   Okita, Hajime ⁱ   Miyachi, Mitsuru ^g   Souzaki, Ryota ^j   Taguchi, Tomoaki ^j   Koh, Katsuyoshi ^e   Hanada, Ryoji ^e   Kato, Keisuke ^k   Nomura, Yuko ^l   Akiyama, Masaharu ^m   Oka, Akira ^a   Igarashi, Takashi ^a,n   Miyano, Satoru ^c   Aburatani, Hiroyuki ^f   Hayashi, Yasuhide ^o   Ogawa, Seishi ^a,b   Takita, Junko ^a   more..

^a UNIVERSITY OF TOKYO   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e SAITAMA CHILDREN'S MEDICAL CENTER   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

^g KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^h KANAGAWA CHILDREN'S MEDICAL CENTER   (Japan)

ⁱ NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^j KYUSHU UNIVERSITY   (Japan)

^k Ibaraki Children's Hospital   (Japan)

^l FUKUOKA UNIVERSITY   (Japan)

^m JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁿ NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^o Gunma Children's Medical Center   (Japan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AKAP9 PROTEIN; ARID1A PROTEIN; BCOR PROTEIN; C15ORF2 PROTEIN; COL5A2 PROTEIN; COLLAGEN; DNAH5 PROTEIN; FBXW7 PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR 4; FREM2 PROTEIN; GAB1 PROTEIN; K RAS PROTEIN; KIF21A PROTEIN; NEB PROTEIN; NLRC5 PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PIK3CA PROTEIN; PROTEIN; PROTEIN KINASE B; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; PTPRO PROTEIN; RAS PROTEIN; ROBO1 PROTEIN; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR PAX7; TRANSCRIPTOME; TTN PROTEIN; UNCLASSIFIED DRUG; BCOR PROTEIN, HUMAN; BETA CATENIN; CELL CYCLE PROTEIN; CTNNB1 PROTEIN, HUMAN; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; FGFR4 PROTEIN, HUMAN; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; MESSENGER RNA; ONCOPROTEIN; PAIRED BOX TRANSCRIPTION FACTOR; PAX3 PROTEIN, HUMAN; PAX7 PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; REPRESSOR PROTEIN; TP53 PROTEIN, HUMAN; TRANSCRIPTION FACTOR FKHR; UBIQUITIN PROTEIN LIGASE;

CANCER; GENE EXPRESSION; GENETIC ANALYSIS; HISTOLOGY; METHYLATION; MOLECULAR ANALYSIS; MUTATION; NUCLEIC ACID ANALYSIS; PHENOTYPE;

ALLELIC IMBALANCE; ARTICLE; CANCER PROGNOSIS; CELL CYCLE REGULATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; EXOME; GENE DOSAGE; GENE FREQUENCY; GENE FUSION; GENE IDENTIFICATION; GENE INACTIVATION; GENOME ANALYSIS; HISTOLOGY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MOLECULAR PATHOLOGY; ONCOGENE H RAS; ONCOGENE N RAS; PROTEIN METHYLATION; RHABDOMYOSARCOMA; RNA SEQUENCE; SOMATIC MUTATION; ADOLESCENT; CHILD; CLASSIFICATION; EMBRYONAL RHABDOMYOSARCOMA; FEMALE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; INFANT; MALE; METABOLISM; MUTATION; PRESCHOOL CHILD; PROGNOSIS; YOUNG ADULT;

ADOLESCENT; BETA CATENIN; CELL CYCLE PROTEINS; CHILD; CHILD, PRESCHOOL; DNA METHYLATION; EPIGENESIS, GENETIC; EXOME; F-BOX PROTEINS; FEMALE; FORKHEAD BOX PROTEIN O1; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INFANT; MALE; MUTATION; PAIRED BOX TRANSCRIPTION FACTORS; PAX3 TRANSCRIPTION FACTOR; PAX7 TRANSCRIPTION FACTOR; PROGNOSIS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RAS PROTEINS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 4; REPRESSOR PROTEINS; RHABDOMYOSARCOMA; RHABDOMYOSARCOMA, ALVEOLAR; RHABDOMYOSARCOMA, EMBRYONAL; RNA, MESSENGER; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES; YOUNG ADULT;

EID: 84936802728     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8557     Document Type: Article

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