The tyrosine kinase c-Abl promotes homeodomaininteracting protein kinase 2 (HIPK2) accumulation and activation in response to DNA damage

Journal of Biological Chemistry

Volumn 290, Issue 27, 2015, Pages 16478-16488

  Reuven, Nina ^a   Adler, Julia ^a   Porat, Ziv ^a   Polonio Vallon, Tilman ^b   Hofmann, Thomas G ^b   Shaul, Yosef ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL DEATH; DNA; PHOSPHORYLATION;

APOPTOTIC RESPONSE; DNA DAMAGES; HOMEODOMAIN-INTERACTING PROTEIN KINASE 2; KINASE ACTIVITY; TYROSINE KINASE;

ENZYMES;

ABELSON KINASE; DNA; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; SIAH 1 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CARRIER PROTEIN; HIPK2 PROTEIN, HUMAN; PROTEIN BINDING;

APOPTOSIS; ARTICLE; BIOACCUMULATION; CELL DENSITY; CELL FATE; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GAMMA RADIATION; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; CHEMISTRY; DIMERIZATION; GENETICS; METABOLISM; PHOSPHORYLATION; RADIATION RESPONSE; TUMOR CELL LINE; ULTRAVIOLET RADIATION;

APOPTOSIS; CARRIER PROTEINS; CELL LINE, TUMOR; DIMERIZATION; DNA DAMAGE; ENZYME ACTIVATION; GAMMA RAYS; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-ABL; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 84936791656     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.628982     Document Type: Article

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